Panama Canal, Central America Cruises : Best Cruise Prices

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Ports

Miami, Florida
George Town, Grand Cayman
Cartagena, Colombia
Panama Canal (Cruise Into Canal)
Colon, Panama
Puerto Limon, Costa Rica
Harvest Caye, Belize
Cozumel, Mexico

Ports

Miami, Florida - George Town, Grand Cayman - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - Harvest Caye, Belize - Cozumel, Mexico - View more ports

11 Night Panama Canal: Mexico Costa Rica & Belize (Miami Roundtrip)

Norwegian Gem L

3.8

(2493 Reviews)

2025 sail dates: Jan 03

$1091*

$99/night*

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Ports

New York, New York
Ft. Lauderdale (Port Everglades), Florida
Philipsburg, St. Maarten
Castries, St. Lucia
Bridgetown, Barbados
Devils Island, French Guiana
Cruise Amazon River
CRUISE BARRA NORTE RIVER
Macapa, Brazil
Cross The Equator
Santarem, Brazil
Boca Da Valeria, Brazil
Manaus, Brazil
Parintins, Brazil
Alter Do Chao, Brazil
Port of Spain
Willemstad, Curacao
Oranjestad, Aruba

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Ports

New York, New York - Ft. Lauderdale (Port Everglades), Florida - Philipsburg, St. Maarten - Castries, St. Lucia - Bridgetown, Barbados - Devils Island, French Guiana - Cruise Amazon River - CRUISE BARRA NORTE RIVER - Macapa, Brazil - Cross The Equator - Santarem, Brazil - Boca Da Valeria, Brazil - Manaus, Brazil - Parintins, Brazil - Alter Do Chao, Brazil - Port of Spain - Willemstad, Curacao - Oranjestad, Aruba - View more ports

30 Night Amazon Explorer (New York To Ft. Lauderdale)

Volendam M

4.0

(296 Reviews)

2025 sail dates: Nov 21

$5284*

$176/night*

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Ports

Ft. Lauderdale (Port Everglades), Florida
George Town, Grand Cayman
Cartagena, Colombia
Colon, Panama
Panama Canal Transit
Puntarenas, Costa Rica
Puerto Quetzal, Guatemala
Puerto Vallarta, Mexico
Mazatlan, Mexico
San Pedro (Los Angeles), California

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Ports

Ft. Lauderdale (Port Everglades), Florida - George Town, Grand Cayman - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Puerto Vallarta, Mexico - Mazatlan, Mexico - San Pedro (Los Angeles), California - View more ports

17 Night Panama Canal Westward (Ft. Lauderdale To Los Angeles)

Celebrity Summit M

4.1

(2235 Reviews)

2026 sail dates: Apr 13

$2636*

$155/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$2636*	$2969*	$3635*	$8971*
See Offers	$2773*	$3107*	$3772*	$9057*
See Offers	$2774*	$3107*	$3773*	$9057*
	$2773*	$3107*	$3772*	$9057*
See Offers	$2774*	$3107*	$3773*	$9057*
See Offers	$2773*	$3107*	$3772*	$9057*

Ports

Ft. Lauderdale (Port Everglades), Florida
Cartagena, Colombia
Panama Canal Transit
PANAMA CITY (FUERTE AMADOR), PANAMA
Puntarenas, Costa Rica
Puerto Quetzal, Guatemala
Manzanillo, Mexico
San Francisco, California

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Ports

Ft. Lauderdale (Port Everglades), Florida - Cartagena, Colombia - Panama Canal Transit - PANAMA CITY (FUERTE AMADOR), PANAMA - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Manzanillo, Mexico - San Francisco, California - View more ports

16 Night Panama Canal - Ocean To Ocean (Ft. Lauderdale To San Francisco)

Ruby Princess L

4.1

(1571 Reviews)

2026 sail dates: Oct 07

$1399*

$87/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1399*	$1699*	$2699*	$5699*
See Offers	$1399*	$1539*	$2699*	$3799*
See Offers	$1399*	$1539*	$2699*	$3799*
	$1399*	$1539*	$2699*	$3799*
See Offers	$1399*	$1539*	$2699*	$3799*
See Offers	$1399*	$1539*	$2699*	$3799*
See Offers	$1399*	$1539*	$2699*	$3799*

Ports

Miami, Florida
Falmouth, Jamaica
Cartagena, Colombia
Cruise Gatun Lake (Inside Panama Canal)
Colon, Panama
Puerto Limon, Costa Rica
Harvest Caye, Belize
Cozumel, Mexico

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Ports

Miami, Florida - Falmouth, Jamaica - Cartagena, Colombia - Cruise Gatun Lake (Inside Panama Canal) - Colon, Panama - Puerto Limon, Costa Rica - Harvest Caye, Belize - Cozumel, Mexico - View more ports

11 Night Panama Canal Partial Transit: Mexico Jamaica & Costa Rica (Miami Roundtrip)

Norwegian Sun M

3.7

(2010 Reviews)

2026 sail dates: Dec 10

2027 sail dates: Jan 02, Mar 13

$1561*

$142/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1561*	$2011*	$3061*	$7411*
See Offers	$1346*	$1796*	$2846*	$3846*
See Offers	$1561*	$2011*	$3061*	$4061*
	$1346*	$1796*	$2846*	$3846*
See Offers	$1561*	$2011*	$3061*	$4061*
See Offers	$1561*	$2011*	$3061*	$4061*
See Offers	$1346*	$1796*	$2846*	$3846*
See Offers	$1561*	$2011*	$3061*	$4061*
See Offers	$1346*	$1796*	$2846*	$3846*
See Offers	$1661*	$2111*	$3361*	$7711*
See Offers	$1446*	$1896*	$3146*	$4146*
See Offers	$1661*	$2111*	$3361*	$4361*
	$1446*	$1896*	$3146*	$4146*
See Offers	$1661*	$2111*	$3361*	$4361*
See Offers	$1661*	$2111*	$3361*	$4361*
See Offers	$1446*	$1896*	$3146*	$4146*
See Offers	$1661*	$2111*	$3361*	$4361*
See Offers	$1446*	$1896*	$3146*	$4146*
See Offers	$1811*	$2261*	$3511*	$7861*
See Offers	$1596*	$2046*	$3296*	$4296*
See Offers	$1811*	$2261*	$3511*	$4511*
	$1596*	$2046*	$3296*	$4296*
See Offers	$1811*	$2261*	$3511*	$4511*
See Offers	$1811*	$2261*	$3511*	$4511*
See Offers	$1596*	$2046*	$3296*	$4296*
See Offers	$1811*	$2261*	$3511*	$4511*
See Offers	$1596*	$2046*	$3296*	$4296*

Ports

Ft. Lauderdale (Port Everglades), Florida
Oranjestad, Aruba
Cartagena, Colombia
Panama Canal (Cruise Into Canal)
Colon, Panama
Puerto Limon, Costa Rica
George Town, Grand Cayman

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Ports

Ft. Lauderdale (Port Everglades), Florida - Oranjestad, Aruba - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports

12 Night Panama Canal With Costa Rica & Caribbean Holiday (Ft. Lauderdale Roundtrip)

Caribbean Princess L

3.9

(1889 Reviews)

2026 sail dates: Dec 17, Dec 29

$1349*

$112/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1349*	$1549*	$2299*	$4499*
See Offers	$1349*	$1489*	$2299*	$3099*
See Offers	$1349*	$1489*	$2299*	$3099*
See Offers	$1349*	$1489*	$2299*	$3099*
	$1349*	$1549*	$2299*	$4499*
See Offers	$1349*	$1509*	$2299*	$3099*
See Offers	$1349*	$1509*	$2299*	$3099*
	$1349*	$1509*	$2299*	$3099*
See Offers	$1349*	$1509*	$2299*	$3099*
See Offers	$1349*	$1509*	$2299*	$3099*
See Offers	$1349*	$1509*	$2299*	$3099*

Ports

Ft. Lauderdale (Port Everglades), Florida
Kralendijk, Bonaire
Willemstad, Curacao
Cartagena, Colombia
Panama Canal (Cruise Into Canal)
Colon, Panama
Puerto Limon, Costa Rica
George Town, Grand Cayman

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Ports

Ft. Lauderdale (Port Everglades), Florida - Kralendijk, Bonaire - Willemstad, Curacao - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports

12 Night Panama Canal With Costa Rica & Caribbean (Ft. Lauderdale Roundtrip)

Emerald Princess L

4.0

(1206 Reviews)

2025 sail dates: Feb 28

$1248*

$104/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1248*	$1898*	$2648*	$5029*
See Offers	$1248*	$1354*	$2648*	$4018*
See Offers	$1248*	$1354*	$2648*	$4018*
	$1248*	$1354*	$2648*	$4018*
See Offers	$1248*	$1354*	$2549*	$3799*
See Offers	$1248*	$1354*	$2648*	$4018*
See Offers	$1248*	$1354*	$2648*	$4018*

Ports

San Antonio, Chile
Coquimbo (La Serena), Chile
General San Martin (Pisco), Peru
Callao (Lima), Peru
Salaverry (Trujillo), Peru
Manta, Ecuador
Fuerte Amador, Panama
Panama Canal Transit
George Town, Grand Cayman
Ft. Lauderdale (Port Everglades), Florida

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Ports

San Antonio, Chile - Coquimbo (La Serena), Chile - General San Martin (Pisco), Peru - Callao (Lima), Peru - Salaverry (Trujillo), Peru - Manta, Ecuador - Fuerte Amador, Panama - Panama Canal Transit - George Town, Grand Cayman - Ft. Lauderdale (Port Everglades), Florida - View more ports

17 Night Inca & Panama Canal Discovery (San Antonio To Ft. Lauderdale)

Oosterdam M

4.1

(889 Reviews)

2025 sail dates: Mar 19

2026 sail dates: Mar 22

$1694*

$100/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1694*	$2094*	$3694*	$4494*
See Offers	$1759*	$2159*	$3759*	$4559*
See Offers	$1759*	$2159*	$3592*	$4559*
	N/A	N/A	N/A	$4534*
	$1759*	$2159*	$3759*	$4559*
See Offers	$1759*	$2159*	$3759*	$4559*
See Offers	$1759*	$2159*	$3759*	$4559*
See Offers	$1759*	$2159*	$3759*	$4559*
	$2509*	$2709*	$3849*	$5159*
See Offers	$2579*	$2779*	$3799*	$5229*
See Offers	$2579*	$2779*	$3919*	$5229*
	N/A	N/A	N/A	$5204*
	$2579*	$2779*	$3799*	$5229*
See Offers	$2579*	$2779*	$3799*	$5229*
See Offers	$2579*	$2779*	$3789*	$5229*
See Offers	$2579*	$2779*	$3789*	$5229*

Ports

Tampa, Florida
Puerto Limon, Costa Rica
Colon, Panama
George Town, Grand Cayman

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Ports

Tampa, Florida - Puerto Limon, Costa Rica - Colon, Panama - George Town, Grand Cayman - View more ports

8 Night Panama Canal - Partial Transit (Tampa Roundtrip)

Carnival Legend L

3.9

(2185 Reviews)

2024 sail dates: Dec 21

2025 sail dates: Feb 15

$1313*

$164/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1653*	N/A	$2053*	$3741*
	$1645*	$1891*	$2045*	$3733*
	$1653*	N/A	$2053*	$3741*
See Offers	$1653*	N/A	$2053*	$3741*
See Offers	$1653*	N/A	$2053*	$3741*
	$1313*	N/A	$1953*	$3325*
	$1305*	N/A	$1945*	$3317*
	$1313*	N/A	$1953*	$3325*
See Offers	$1313*	N/A	$1953*	$3325*
See Offers	$1313*	N/A	$1953*	$3325*

Ports

Baltimore, Maryland
Half Moon Cay, Bahamas (Private Island)
Ocho Rios, Jamaica
Puerto Limon, Costa Rica
Colon, Panama
Grand Turk Island

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Ports

Baltimore, Maryland - Half Moon Cay, Bahamas (Private Island) - Ocho Rios, Jamaica - Puerto Limon, Costa Rica - Colon, Panama - Grand Turk Island - View more ports

14 Night Panama Canal: Carnival Journeys (Baltimore Roundtrip)

Carnival Pride L

4.0

(3004 Reviews)

2025 sail dates: Jan 12

$2425*

$173/night*

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Partners	Bonus Offers	Inside	Oceanview	Balcony	Suite
		N/A	N/A	$2425*	$4341*

Ports

San Francisco, California
San Pedro (Los Angeles), California
Cabo San Lucas, Mexico
Acapulco, Mexico
Puerto Quetzal, Guatemala
Puerto Caldera, Costa Rica
Panama City, Panama
Panama Canal Transit
Cartagena, Colombia
Miami, Florida

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Ports

San Francisco, California - San Pedro (Los Angeles), California - Cabo San Lucas, Mexico - Acapulco, Mexico - Puerto Quetzal, Guatemala - Puerto Caldera, Costa Rica - Panama City, Panama - Panama Canal Transit - Cartagena, Colombia - Miami, Florida - View more ports

18 Night Panama Canal: Mexico Costa Rica & Colombia (San Francisco To Miami)

Norwegian Joy L

4.2

(944 Reviews)

2025 sail dates: Oct 02

$2404*

$134/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$2404*	$3054*	$3504*	$9954*
See Offers	$2404*	$3054*	$3504*	$4104*
See Offers	$2404*	$3054*	$3504*	$4104*
	$2404*	$3054*	$3504*	$4104*
See Offers	$2404*	$3054*	$3504*	$4104*
See Offers	$2404*	$3054*	$3504*	$4104*
See Offers	$2404*	$3054*	$3504*	$4104*
See Offers	$2404*	$3054*	$3504*	$4104*
See Offers	$2404*	$3054*	$3504*	$4104*

Ports

Seattle, Washington
Vancouver (Canada Place), British Columbia
Santa Barbara, California
San Diego, California
Puerto Vallarta, Mexico
Huatulco, Mexico
Puerto Chiapas (Tapachula), Mexico
Puerto Quetzal, Guatemala
Acajutla
Puntarenas, Costa Rica
Panama Canal Transit
Oranjestad, Aruba
Ft. Lauderdale (Port Everglades), Florida

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Ports

Seattle, Washington - Vancouver (Canada Place), British Columbia - Santa Barbara, California - San Diego, California - Puerto Vallarta, Mexico - Huatulco, Mexico - Puerto Chiapas (Tapachula), Mexico - Puerto Quetzal, Guatemala - Acajutla - Puntarenas, Costa Rica - Panama Canal Transit - Oranjestad, Aruba - Ft. Lauderdale (Port Everglades), Florida - View more ports

22 Night Panama Canal (Seattle To Ft. Lauderdale)

Eurodam L

4.1

(1100 Reviews)

2025 sail dates: Oct 04

$2704*

$123/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$2704*	$3204*	$4204*	$6979*
See Offers	$2879*	$3379*	$4379*	$7154*
See Offers	$2879*	$3379*	$4379*	$7154*
	N/A	N/A	N/A	$7129*
	$2879*	$3379*	$4379*	$7154*
See Offers	$2879*	$3379*	$4379*	$7154*
See Offers	$2879*	$3379*	$4379*	$7154*
See Offers	$2879*	$3379*	$4379*	$7154*

Panama Canal, Central America cruises 385 Panama Canal, Central America Cruises Found

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