Norwegian Cruise Line to Panama Canal, Central America

Sponsored cruise

Ports

Miami, Florida
George Town, Grand Cayman
Cartagena, Colombia
Panama Canal (Cruise Into Canal)
Colon, Panama
Puerto Limon, Costa Rica
Harvest Caye, Belize
Cozumel, Mexico

Ports

Miami, Florida - George Town, Grand Cayman - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - Harvest Caye, Belize - Cozumel, Mexico - View more ports

11 Night Panama Canal: Mexico Costa Rica & Belize (Miami Roundtrip)

Norwegian Gem L

3.8

(2493 Reviews)

2025 sail dates: Jan 03

$1091*

$99/night*

Inside

View Deal

Loading itinerary...

Loading reviews...

Read all 2493 Norwegian Gem reviews

Ports

San Pedro (Los Angeles), California
Cabo San Lucas, Mexico
Acapulco, Mexico
Puerto Quetzal, Guatemala
Puerto Caldera, Costa Rica
Panama City, Panama
Panama Canal Transit
Cartagena, Colombia
Miami, Florida

View more ports

Ports

San Pedro (Los Angeles), California - Cabo San Lucas, Mexico - Acapulco, Mexico - Puerto Quetzal, Guatemala - Puerto Caldera, Costa Rica - Panama City, Panama - Panama Canal Transit - Cartagena, Colombia - Miami, Florida - View more ports

15 Night Panama Canal: Mexico & Costa Rica (Los Angeles To Miami)

Norwegian Bliss XL

4.1

(1347 Reviews)

2025 sail dates: Dec 05

2026 sail dates: Feb 01

$1804*

$120/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 1347 Norwegian Bliss reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1804*	$2374*	$2954*	$8674*
See Offers	$1804*	$2374*	$2954*	$3424*
See Offers	$1804*	$2374*	$2954*	$3424*
See Offers	$1804*	$2374*	$2954*	$3424*
See Offers	$1804*	$2374*	$2954*	$3424*
See Offers	$1804*	$2374*	$2954*	$3424*
	$1804*	$2374*	$2954*	$3424*
See Offers	$1682*	$2195*	$2717*	$3140*
See Offers	$1682*	$2195*	$2717*	$3140*
See Offers	$2024*	$2734*	$3454*	$8724*
See Offers	$2024*	$2734*	$3373*	$3923*
See Offers	$2024*	$2734*	$3454*	$3924*
See Offers	$2024*	$2734*	$3373*	$3923*
See Offers	$2024*	$2734*	$3373*	$3923*
See Offers	$2024*	$2734*	$3454*	$3924*
	$2024*	$2734*	$3373*	$3923*
See Offers	$2024*	$2734*	$3454*	$3924*
See Offers	$2024*	$2734*	$3454*	$3924*

Ports

Miami, Florida
Great Stirrup Cay (Cruise Line Private Island), Bahamas
CABO ROJO, DOMINICAN REPUBLIC
Oranjestad, Aruba
Willemstad, Curacao
Cartagena, Colombia
Colon, Panama
Cruise Gatun Lake (Inside Panama Canal)
Puerto Limon, Costa Rica

View more ports

Ports

Miami, Florida - Great Stirrup Cay (Cruise Line Private Island), Bahamas - CABO ROJO, DOMINICAN REPUBLIC - Oranjestad, Aruba - Willemstad, Curacao - Cartagena, Colombia - Colon, Panama - Cruise Gatun Lake (Inside Panama Canal) - Puerto Limon, Costa Rica - View more ports

12 Night Panama Canal Partial Transit: Bahamas & Costa Rica (Miami Roundtrip)

Norwegian Sun M

3.7

(2010 Reviews)

2026 sail dates: Dec 21

2027 sail dates: Jan 25, Mar 01

$1882*

$157/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 2010 Norwegian Sun reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$2532*	$3082*	$4582*	$10182*
See Offers	$2532*	$3082*	$4582*	$6082*
See Offers	$2532*	$3082*	$4582*	$6082*
See Offers	$2532*	$3082*	$4582*	$6082*
See Offers	$2532*	$3082*	$4582*	$6082*
See Offers	$2532*	$3082*	$4582*	$6082*
	$2532*	$3082*	$4582*	$6082*
See Offers	$2532*	$3082*	$4582*	$6082*
See Offers	$2532*	$3082*	$4582*	$6082*
See Offers	$1882*	$2432*	$3782*	$8532*
See Offers	$1882*	$2432*	$3782*	$4882*
See Offers	$1882*	$2432*	$3782*	$4882*
See Offers	$1882*	$2432*	$3782*	$4882*
See Offers	$1882*	$2432*	$3782*	$4882*
See Offers	$1882*	$2432*	$3782*	$4882*
	$1882*	$2432*	$3782*	$4882*
See Offers	$1882*	$2432*	$3782*	$4882*
See Offers	$1882*	$2432*	$3782*	$4882*
See Offers	$1932*	$2482*	$3832*	$8582*
See Offers	$1932*	$2482*	$3832*	$4932*
See Offers	$1932*	$2482*	$3832*	$4932*
See Offers	$1932*	$2482*	$3832*	$4932*
See Offers	$1932*	$2482*	$3832*	$4932*
See Offers	$1932*	$2482*	$3832*	$4932*
	$1932*	$2482*	$3832*	$4932*
See Offers	$1932*	$2482*	$3832*	$4932*
See Offers	$1932*	$2482*	$3832*	$4932*

Ports

Miami, Florida
Cartagena, Colombia
Colon, Panama
Panama Canal Transit
Puerto Caldera, Costa Rica
Puerto Quetzal, Guatemala
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Pedro (Los Angeles), California

View more ports

Ports

Miami, Florida - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Puerto Caldera, Costa Rica - Puerto Quetzal, Guatemala - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - View more ports

15 Night Panama Canal: Mexico & Colombia (Miami To Los Angeles)

Norwegian Bliss XL

4.1

(1347 Reviews)

2025 sail dates: Feb 22

$1588*

$106/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 1347 Norwegian Bliss reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1588*	$1788*	$2338*	$9428*
See Offers	$1588*	$1888*	$2338*	$2488*
See Offers	$1588*	$1788*	$2338*	$2488*
See Offers	$1588*	$1888*	$2338*	$2488*
See Offers	$1588*	$1888*	$2338*	$2488*
See Offers	$1588*	$1788*	$2338*	$2488*
	$1588*	$1888*	$2338*	$2488*
See Offers	$1588*	$1788*	$2338*	$2488*
See Offers	$1588*	$1788*	$2338*	$2488*

Ports

Miami, Florida
Cartagena, Colombia
Panama City, Panama
Panama Canal Transit
Puntarenas, Costa Rica
Puerto Quetzal, Guatemala
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Pedro (Los Angeles), California
San Francisco, California

View more ports

Ports

Miami, Florida - Cartagena, Colombia - Panama City, Panama - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - San Francisco, California - View more ports

17 Night Panama Canal: Mexico & Costa Rica (Miami To San Francisco)

Norwegian Encore XL

4.3

(691 Reviews)

2025 sail dates: Mar 30

$2046*

$120/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 691 Norwegian Encore reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$2046*	$2286*	$2816*	$10016*
See Offers	$2046*	$2286*	$2816*	$2916*
See Offers	$2046*	$2286*	$2816*	$2916*
See Offers	$2046*	$2286*	$2816*	$2916*
See Offers	$2046*	$2286*	$2816*	$2916*
See Offers	$2046*	$2286*	$2816*	$2916*
	$2046*	$2286*	$2816*	$2916*
See Offers	$2046*	$2286*	$2816*	$2916*
See Offers	$2036*	$2286*	$2816*	$2916*

Ports

Miami, Florida
Cartagena, Colombia
Panama Canal Transit
Panama City, Panama
Puerto Caldera, Costa Rica
Puerto Quetzal, Guatemala
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Pedro (Los Angeles), California

View more ports

Ports

Miami, Florida - Cartagena, Colombia - Panama Canal Transit - Panama City, Panama - Puerto Caldera, Costa Rica - Puerto Quetzal, Guatemala - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - View more ports

15 Night Panama Canal: Mexico Colombia & Costa Rica (Miami To Seattle)

Norwegian Encore XL

4.3

(691 Reviews)

2025 sail dates: Mar 30

$1872*

$125/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 691 Norwegian Encore reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1872*	$2222*	$2752*	$9952*
See Offers	$1872*	$2222*	$2752*	$2852*
See Offers	$1872*	$2222*	$2752*	$2852*
See Offers	$1872*	$2222*	$2752*	$2852*
See Offers	$1872*	$2222*	$2752*	$2852*
See Offers	$1872*	$2222*	$2752*	$2852*
	$1872*	$2222*	$2752*	$2852*
See Offers	$1872*	$2222*	$2752*	$2852*
See Offers	$1872*	$2222*	$2752*	$2852*

Ports

Miami, Florida
Cartagena, Colombia
Colon, Panama
Panama Canal Transit
Puerto Caldera, Costa Rica
Puerto Quetzal, Guatemala
Acapulco, Mexico
Cabo San Lucas, Mexico
San Pedro (Los Angeles), California

View more ports

Ports

Miami, Florida - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Puerto Caldera, Costa Rica - Puerto Quetzal, Guatemala - Acapulco, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - View more ports

15 Night Panama Canal: Mexico & Costa Rica (Miami To Los Angeles)

Norwegian Encore XL

4.3

(691 Reviews)

2025 sail dates: Nov 29

$1915*

$128/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 691 Norwegian Encore reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1915*	$2505*	$3175*	$9075*
See Offers	$1915*	$2505*	$3175*	$3465*
See Offers	$1915*	$2505*	$3175*	$3465*
See Offers	$1915*	$2505*	$3175*	$3465*
See Offers	$1915*	$2505*	$3175*	$3465*
See Offers	$1915*	$2505*	$3175*	$3465*
	$1915*	$2505*	$3175*	$3465*
See Offers	$1915*	$2505*	$3175*	$3465*
See Offers	$1915*	$2505*	$3175*	$3465*

Ports

San Pedro (Los Angeles), California
Cabo San Lucas, Mexico
Mazatlan, Mexico
Puerto Vallarta, Mexico
Puerto Quetzal, Guatemala
Puerto Caldera, Costa Rica
Panama Canal Transit
Colon, Panama
Cartagena, Colombia
Miami, Florida

View more ports

Ports

San Pedro (Los Angeles), California - Cabo San Lucas, Mexico - Mazatlan, Mexico - Puerto Vallarta, Mexico - Puerto Quetzal, Guatemala - Puerto Caldera, Costa Rica - Panama Canal Transit - Colon, Panama - Cartagena, Colombia - Miami, Florida - View more ports

16 Night Panama Canal: Mexico & Colombia (Los Angeles To Miami)

Norwegian Joy L

4.2

(944 Reviews)

2025 sail dates: Jan 05

$1204*

$75/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 944 Norwegian Joy reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1204*	$1654*	$1704*	$4954*
See Offers	$1204*	$1654*	$1704*	$1884*
See Offers	$1204*	$1654*	$1704*	$1884*
See Offers	$1204*	$1654*	$1704*	$1884*
See Offers	$1204*	$1654*	$1704*	$1884*
See Offers	$1204*	$1654*	$1704*	$1884*
	$1204*	$1654*	$1704*	$1884*
See Offers	$1204*	$1654*	$1704*	$1884*
See Offers	$1204*	$1654*	$1704*	$1884*

Ports

Miami, Florida
Cartagena, Colombia
Panama Canal Transit
Panama City, Panama
Puntarenas, Costa Rica
Puerto Quetzal, Guatemala
Acapulco, Mexico
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Pedro (Los Angeles), California
San Francisco, California
Victoria, British Columbia
Seattle, Washington

View more ports

Ports

Miami, Florida - Cartagena, Colombia - Panama Canal Transit - Panama City, Panama - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Acapulco, Mexico - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - San Francisco, California - Victoria, British Columbia - Seattle, Washington - View more ports

22 Night Panama Canal: Mexico & Costa Rica (Miami To Seattle)

Norwegian Encore XL

4.3

(691 Reviews)

2026 sail dates: Apr 11

$2929*

$133/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 691 Norwegian Encore reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$2929*	$3819*	$4789*	$12379*
See Offers	$2873*	$3819*	$4673*	$5473*
See Offers	$2929*	$3819*	$4789*	$5479*
See Offers	$2873*	$3819*	$4673*	$5473*
See Offers	$2873*	$3819*	$4673*	$5473*
See Offers	$2929*	$3819*	$4789*	$5479*
	$2873*	$3819*	$4673*	$5473*
See Offers	$2929*	$3819*	$4789*	$5479*
See Offers	$2929*	$3819*	$4789*	$5479*

Ports

Miami, Florida
Great Stirrup Cay (Cruise Line Private Island), Bahamas
Cartagena, Colombia
Colon, Panama
Cruise Gatun Lake (Inside Panama Canal)
Puerto Limon, Costa Rica
Falmouth, Jamaica
George Town, Grand Cayman

View more ports

Ports

Miami, Florida - Great Stirrup Cay (Cruise Line Private Island), Bahamas - Cartagena, Colombia - Colon, Panama - Cruise Gatun Lake (Inside Panama Canal) - Puerto Limon, Costa Rica - Falmouth, Jamaica - George Town, Grand Cayman - View more ports

11 Night Panama Canal Partial Transit: Mexico Jamaica & Costa Rica (Miami Roundtrip)

Norwegian Sun M

3.7

(2010 Reviews)

2026 sail dates: Nov 18, Nov 29

$1561*

$142/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 2010 Norwegian Sun reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1981*	$2431*	$3481*	$7831*
See Offers	$1981*	$2431*	$3481*	$4481*
See Offers	$1981*	$2431*	$3481*	$4481*
See Offers	$1981*	$2431*	$3481*	$4481*
See Offers	$1981*	$2431*	$3481*	$4481*
See Offers	$1981*	$2431*	$3481*	$4481*
	$1981*	$2431*	$3481*	$4481*
See Offers	$1981*	$2431*	$3481*	$4481*
See Offers	$1981*	$2431*	$3481*	$4481*
See Offers	$1561*	$2011*	$3061*	$7411*
See Offers	$1561*	$2011*	$3061*	$4061*
See Offers	$1561*	$2011*	$3061*	$4061*
See Offers	$1561*	$2011*	$3061*	$4061*
See Offers	$1561*	$2011*	$3061*	$4061*
See Offers	$1561*	$2011*	$3061*	$4061*
	$1561*	$2011*	$3061*	$4061*
See Offers	$1561*	$2011*	$3061*	$4061*
See Offers	$1561*	$2011*	$3061*	$4061*

Ports

San Pedro (Los Angeles), California
Cabo San Lucas, Mexico
Puerto Vallarta, Mexico
Puerto Quetzal, Guatemala
Puerto Caldera, Costa Rica
Panama City, Panama
Panama Canal Transit
Cartagena, Colombia
Miami, Florida

View more ports

Ports

San Pedro (Los Angeles), California - Cabo San Lucas, Mexico - Puerto Vallarta, Mexico - Puerto Quetzal, Guatemala - Puerto Caldera, Costa Rica - Panama City, Panama - Panama Canal Transit - Cartagena, Colombia - Miami, Florida - View more ports

15 Night Panama Canal: Mexico & Colombia (Los Angeles To Miami)

Norwegian Joy L

4.2

(944 Reviews)

2025 sail dates: Feb 06

$1386*

$92/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 944 Norwegian Joy reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1386*	$1786*	$1906*	$4786*
See Offers	$1386*	$1886*	$1906*	$2106*
See Offers	$1386*	$1786*	$1906*	$2106*
See Offers	$1386*	$1886*	$1906*	$2106*
See Offers	$1386*	$1886*	$1906*	$2106*
See Offers	$1386*	$1786*	$1906*	$2106*
	$1386*	$1886*	$1906*	$2106*
See Offers	$1269*	$1609*	$1711*	$1881*
See Offers	$1269*	$1609*	$1711*	$1881*

Norwegian Cruise Line Cruises to Panama Canal, Central America 59 cruises on Norwegian Cruise Line found

Your search Clear selections

59 cruises found

Sort by

Filter by

More popular destinations for Norwegian Cruise Line

More popular cruise lines that sail to Panama Canal, Central America

More popular departure ports with sailings to Panama Canal, Central America