Panama Canal, Central America cruises 373 Panama Canal, Central America Cruises Found
Your search Clear selections
373 cruises found
Sort by
Filter by
Ports
- New York, New York
- Ft. Lauderdale (Port Everglades), Florida
- Philipsburg, St. Maarten
- Castries, St. Lucia
- Bridgetown, Barbados
- Devils Island, French Guiana
- Cruise Amazon River
- CRUISE BARRA NORTE RIVER
- Macapa, Brazil
- Cross The Equator
- Santarem, Brazil
- Boca Da Valeria, Brazil
- Manaus, Brazil
- Parintins, Brazil
- Alter Do Chao, Brazil
- Port of Spain
- Willemstad, Curacao
- Oranjestad, Aruba
Ports
New York, New York - Ft. Lauderdale (Port Everglades), Florida - Philipsburg, St. Maarten - Castries, St. Lucia - Bridgetown, Barbados - Devils Island, French Guiana - Cruise Amazon River - CRUISE BARRA NORTE RIVER - Macapa, Brazil - Cross The Equator - Santarem, Brazil - Boca Da Valeria, Brazil - Manaus, Brazil - Parintins, Brazil - Alter Do Chao, Brazil - Port of Spain - Willemstad, Curacao - Oranjestad, Aruba - View more ports
Ports
- Miami, Florida
- George Town, Grand Cayman
- Cartagena, Colombia
- Panama Canal (Cruise Into Canal)
- Colon, Panama
- Puerto Limon, Costa Rica
- Harvest Caye, Belize
- Cozumel, Mexico
Ports
Miami, Florida - George Town, Grand Cayman - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - Harvest Caye, Belize - Cozumel, Mexico - View more ports
11 Night Panama Canal: Mexico Costa Rica & Belize (Miami Roundtrip)
2025 sail dates:
Ports
- Seattle, Washington
- Vancouver (Canada Place), British Columbia
- Santa Barbara, California
- San Diego, California
- Puerto Vallarta, Mexico
- Huatulco, Mexico
- Puerto Chiapas (Tapachula), Mexico
- Puerto Quetzal, Guatemala
- Acajutla
- Puntarenas, Costa Rica
- Panama Canal Transit
- Oranjestad, Aruba
- Ft. Lauderdale (Port Everglades), Florida
Ports
Seattle, Washington - Vancouver (Canada Place), British Columbia - Santa Barbara, California - San Diego, California - Puerto Vallarta, Mexico - Huatulco, Mexico - Puerto Chiapas (Tapachula), Mexico - Puerto Quetzal, Guatemala - Acajutla - Puntarenas, Costa Rica - Panama Canal Transit - Oranjestad, Aruba - Ft. Lauderdale (Port Everglades), Florida - View more ports
Ports
- Vancouver (Canada Place), British Columbia
- Santa Barbara, California
- San Diego, California
- Puerto Vallarta, Mexico
- Huatulco, Mexico
- Puerto Chiapas (Tapachula), Mexico
- Puerto Quetzal, Guatemala
- Acajutla
- Puntarenas, Costa Rica
- Panama Canal Transit
- Oranjestad, Aruba
- Ft. Lauderdale (Port Everglades), Florida
- Grand Turk Island
- San Juan, Puerto Rico
- Charlotte Amalie, St. Thomas
- Half Moon Cay, Bahamas (Private Island)
Ports
Vancouver (Canada Place), British Columbia - Santa Barbara, California - San Diego, California - Puerto Vallarta, Mexico - Huatulco, Mexico - Puerto Chiapas (Tapachula), Mexico - Puerto Quetzal, Guatemala - Acajutla - Puntarenas, Costa Rica - Panama Canal Transit - Oranjestad, Aruba - Ft. Lauderdale (Port Everglades), Florida - Grand Turk Island - San Juan, Puerto Rico - Charlotte Amalie, St. Thomas - Half Moon Cay, Bahamas (Private Island) - View more ports
Ports
- San Pedro (Los Angeles), California
- Cabo San Lucas, Mexico
- Acapulco, Mexico
- Puerto Quetzal, Guatemala
- Puerto Caldera, Costa Rica
- Panama City, Panama
- Panama Canal Transit
- Cartagena, Colombia
- Miami, Florida
Ports
San Pedro (Los Angeles), California - Cabo San Lucas, Mexico - Acapulco, Mexico - Puerto Quetzal, Guatemala - Puerto Caldera, Costa Rica - Panama City, Panama - Panama Canal Transit - Cartagena, Colombia - Miami, Florida - View more ports
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
See Offers |
$2336* |
$2986* |
$3436* |
$9886* |
|
|
|
See Offers |
$2336* |
$2986* |
$3436* |
$4036* |
|
|
|
See Offers |
$2336* |
$2986* |
$3436* |
$4036* |
|
|
|
See Offers |
$2336* |
$2986* |
$3436* |
$4036* |
|
|
|
See Offers |
$2336* |
$2986* |
$3436* |
$4036* |
|
|
|
See Offers |
$2336* |
$2986* |
$3436* |
$4036* |
|
|
|
See Offers |
$2336* |
$2986* |
$3436* |
$4036* |
|
|
|
$2336* |
$2986* |
$3436* |
$4036* |
Ports
- Ft. Lauderdale (Port Everglades), Florida
- Cartagena, Colombia
- Panama Canal Transit
- Puntarenas, Costa Rica
- Acajutla
- Puerto Quetzal, Guatemala
- Puerto Vallarta, Mexico
- Cabo San Lucas, Mexico
- San Diego, California
- Catalina Island, California
- Vancouver (Canada Place), British Columbia
- Seattle, Washington
Ports
Ft. Lauderdale (Port Everglades), Florida - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Acajutla - Puerto Quetzal, Guatemala - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Diego, California - Catalina Island, California - Vancouver (Canada Place), British Columbia - Seattle, Washington - View more ports
Ports
- Ft. Lauderdale (Port Everglades), Florida
- Oranjestad, Aruba
- Cartagena, Colombia
- Colon, Panama
- Panama Canal (Cruise Into Canal)
- Puerto Limon, Costa Rica
- George Town, Grand Cayman
Ports
Ft. Lauderdale (Port Everglades), Florida - Oranjestad, Aruba - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports
12 Night Panama Canal With Costa Rica & Caribbean (Ft. Lauderdale Roundtrip)
2026 sail dates: Nov 11
2027 sail dates: Feb 03,
Ports
- Ft. Lauderdale (Port Everglades), Florida
- Cartagena, Colombia
- Panama Canal Transit
- Puntarenas, Costa Rica
- Puerto Quetzal, Guatemala
- Puerto Vallarta, Mexico
- San Pedro (Los Angeles), California
Ports
Ft. Lauderdale (Port Everglades), Florida - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Puerto Vallarta, Mexico - San Pedro (Los Angeles), California - View more ports
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
$1099* |
$1309* |
$1709* |
N/A |
||
|
|
See Offers |
$1298* |
$1350* |
$1908* |
$2663* |
|
|
|
See Offers |
$1099* |
$1151* |
$1709* |
$2463* |
|
|
|
See Offers |
$1099* |
$1151* |
$1709* |
$2463* |
|
|
|
See Offers |
$1298* |
$1350* |
$1908* |
$2663* |
|
|
|
See Offers |
$1099* |
$1151* |
$1709* |
$2463* |
|
|
|
$1298* |
$1350* |
$1908* |
$2663* |
Ports
- Miami, Florida
- Cartagena, Colombia
- Colon, Panama
- Panama Canal Transit
- Puerto Caldera, Costa Rica
- Puerto Quetzal, Guatemala
- Acapulco, Mexico
- Puerto Vallarta, Mexico
- Cabo San Lucas, Mexico
- San Pedro (Los Angeles), California
Ports
Miami, Florida - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Puerto Caldera, Costa Rica - Puerto Quetzal, Guatemala - Acapulco, Mexico - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - View more ports
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
See Offers |
$1282* |
$1632* |
$1982* |
$4912* |
|
|
|
See Offers |
$1282* |
$1632* |
$1982* |
$2262* |
|
|
|
See Offers |
$1185* |
$1483* |
$1780* |
$2018* |
|
|
|
See Offers |
$1185* |
$1483* |
$1780* |
$2018* |
|
|
|
See Offers |
$1282* |
$1632* |
$1982* |
$2262* |
|
|
|
See Offers |
$1282* |
$1632* |
$1982* |
$2262* |
|
|
|
See Offers |
$1282* |
$1632* |
$1982* |
$2262* |
|
|
|
$1282* |
$1632* |
$1982* |
$2262* |
Ports
- Ft. Lauderdale (Port Everglades), Florida
- Oranjestad, Aruba
- Willemstad, Curacao
- Cartagena, Colombia
- Cristobal, Panama
- Panama Canal (Cruise Into Canal)
- Puerto Limon, Costa Rica
- George Town, Grand Cayman
Ports
Ft. Lauderdale (Port Everglades), Florida - Oranjestad, Aruba - Willemstad, Curacao - Cartagena, Colombia - Cristobal, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports
Ports
- Ft. Lauderdale (Port Everglades), Florida
- Oranjestad, Aruba
- Cartagena, Colombia
- Colon, Panama
- Panama Canal (Cruise Into Canal)
- Puerto Limon, Costa Rica
- Ocho Rios, Jamaica
Ports
Ft. Lauderdale (Port Everglades), Florida - Oranjestad, Aruba - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - Ocho Rios, Jamaica - View more ports
Ports
- Ft. Lauderdale (Port Everglades), Florida
- Half Moon Cay, Bahamas (Private Island)
- Falmouth, Jamaica
- Mahogany Bay, Roatan, Bay Islands, Honduras
- Belize City, Belize
- Cozumel, Mexico
- Key West, Florida
- Cartagena, Colombia
- Panama Canal Transit
- Puntarenas, Costa Rica
- Puerto Quetzal, Guatemala
- Huatulco, Mexico
- Puerto Vallarta, Mexico
- San Diego, California
Ports
Ft. Lauderdale (Port Everglades), Florida - Half Moon Cay, Bahamas (Private Island) - Falmouth, Jamaica - Mahogany Bay, Roatan, Bay Islands, Honduras - Belize City, Belize - Cozumel, Mexico - Key West, Florida - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Huatulco, Mexico - Puerto Vallarta, Mexico - San Diego, California - View more ports
All prices are per person based on double occupancy and do not include port/government fees and gratuities.
More popular cruise lines sailing to Panama Canal, Central America
More popular departure ports with sailings to Panama Canal, Central America
- Ft. Lauderdale (Port Everglades), Florida Cruises to Panama Canal, Central America
- Miami, Florida Cruises to Panama Canal, Central America
- Tampa, Florida Cruises to Panama Canal, Central America
- Seattle, Washington Cruises to Panama Canal, Central America
- New York, New York Cruises to Panama Canal, Central America