Panama Canal, Central America Cruises : Best Cruise Prices

Ports

Ft. Lauderdale (Port Everglades), Florida
Kralendijk, Bonaire
Oranjestad, Aruba
Cartagena, Colombia
Colon, Panama
Panama Canal (Cruise Into Canal)
Puerto Limon, Costa Rica
Ocho Rios, Jamaica

Ports

Ft. Lauderdale (Port Everglades), Florida - Kralendijk, Bonaire - Oranjestad, Aruba - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - Ocho Rios, Jamaica - View more ports

12 Night Panama Canal With Costa Rica & Caribbean (Ft. Lauderdale Roundtrip)

Emerald Princess L

4.0

(1179 Reviews)

2025 sail dates: Feb 16

$797*

$66/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$797*	$1497*	$2047*	$4790*
See Offers	$798*	$919*	$2048*	$2878*
See Offers	$798*	$919*	$2048*	$2878*
	$798*	$919*	$2048*	$2878*
See Offers	$798*	$919*	$2048*	$2878*
	$798*	$919*	$2048*	$2878*
See Offers	$798*	$919*	$2048*	$2878*
See Offers	$798*	$919*	$2048*	$2878*
	$810*	$931*	$2060*	$2890*
See Offers	$798*	$919*	$2048*	$2878*

Ports

Ft. Lauderdale (Port Everglades), Florida
Kralendijk, Bonaire
Oranjestad, Aruba
Cartagena, Colombia
Colon, Panama
Panama Canal (Cruise Into Canal)
Puerto Limon, Costa Rica
George Town, Grand Cayman

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Ports

Ft. Lauderdale (Port Everglades), Florida - Kralendijk, Bonaire - Oranjestad, Aruba - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports

12 Night Panama Canal With Costa Rica & Caribbean (Ft. Lauderdale Roundtrip)

Emerald Princess L

4.0

(1179 Reviews)

2025 sail dates: Feb 28

$797*

$66/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$797*	$1297*	$1897*	$5178*
See Offers	$798*	$919*	$1898*	$2398*
See Offers	$798*	$919*	$1898*	$2398*
	$798*	$919*	$1898*	$2398*
See Offers	$798*	$919*	$1898*	$2398*
	$798*	$919*	$1898*	$2398*
See Offers	$798*	$919*	$1898*	$2398*
See Offers	$798*	$919*	$1898*	$2398*
	$810*	$931*	$1910*	$2410*

Ports

Miami, Florida
George Town, Grand Cayman
Cartagena, Colombia
Colon, Panama
Cruise Gatun Lake And Panama Canal
Puerto Limon, Costa Rica
Harvest Caye, Belize
Cozumel, Mexico

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Ports

Miami, Florida - George Town, Grand Cayman - Cartagena, Colombia - Colon, Panama - Cruise Gatun Lake And Panama Canal - Puerto Limon, Costa Rica - Harvest Caye, Belize - Cozumel, Mexico - View more ports

11 Night Panama Canal: Mexico Costa Rica & Belize (Miami Roundtrip)

Norwegian Jade L

3.9

(1366 Reviews)

2025 sail dates: Nov 20, Dec 01

$1199*

$109/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1299*	$1599*	$2579*	$7869*
See Offers	$1259*	$1599*	$2529*	$2829*
	$1259*	$1599*	$2529*	$2829*
	$1259*	$1599*	$2529*	$2829*
See Offers	$1299*	$1599*	$2579*	$2829*
	$1259*	$1599*	$2529*	$2829*
See Offers	$1299*	$1599*	$2579*	$2829*
	$1311*	$1611*	$2591*	$2841*
See Offers	$1299*	$1599*	$2579*	$2829*
See Offers	$1299*	$1599*	$2579*	$2829*
See Offers	$1199*	$1549*	$2449*	$7669*
See Offers	$1199*	$1549*	$2449*	$2779*
See Offers	$1199*	$1549*	$2449*	$2779*
	$1199*	$1549*	$2449*	$2779*
See Offers	$1199*	$1549*	$2449*	$2779*
	$1199*	$1549*	$2449*	$2779*
See Offers	$1199*	$1549*	$2449*	$2779*
	$1211*	$1561*	$2461*	$2791*
See Offers	$1199*	$1549*	$2449*	$2779*
See Offers	$1199*	$1549*	$2449*	$2779*

Ports

Miami, Florida
Ocho Rios, Jamaica
Cartagena, Colombia
Colon, Panama
Cruise Gatun Lake And Panama Canal
Puerto Limon, Costa Rica
Harvest Caye, Belize
Cozumel, Mexico

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Ports

Miami, Florida - Ocho Rios, Jamaica - Cartagena, Colombia - Colon, Panama - Cruise Gatun Lake And Panama Canal - Puerto Limon, Costa Rica - Harvest Caye, Belize - Cozumel, Mexico - View more ports

11 Night Panama Canal: Mexico Costa Rica & Belize (Miami Roundtrip)

Norwegian Pearl L

3.8

(2035 Reviews)

2025 sail dates: Dec 22

2026 sail dates: Jan 02

$1229*

$112/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1649*	$2049*	$3529*	$13209*
See Offers	$1609*	$1999*	$3329*	$4049*
See Offers	$1609*	$1999*	$3329*	$4049*
	$1609*	$1999*	$3329*	$4049*
See Offers	$1649*	$2049*	$3529*	$4049*
	$1609*	$1999*	$3329*	$4049*
See Offers	$1649*	$2049*	$3529*	$4049*
	$1661*	$2061*	$3541*	$4061*
See Offers	$1649*	$2049*	$3529*	$4049*
See Offers	$1649*	$2049*	$3529*	$4049*
See Offers	$1229*	$1599*	$2679*	$7519*
See Offers	$1209*	$1549*	$2629*	$2879*
	$1209*	$1549*	$2629*	$2879*
	$1209*	$1549*	$2629*	$2879*
See Offers	$1229*	$1599*	$2679*	$2879*
	$1209*	$1549*	$2629*	$2879*
See Offers	$1229*	$1599*	$2679*	$2879*
	$1241*	$1611*	$2691*	$2891*
See Offers	$1229*	$1599*	$2679*	$2879*
See Offers	$1229*	$1599*	$2679*	$2879*

Ports

Port Canaveral, Florida
Great Stirrup Cay (Cruise Line Private Island), Bahamas
Cartagena, Colombia
Panama Canal Transit
PANAMA CITY (COLON), PANAMA
Puntarenas, Costa Rica
Puerto Quetzal, Guatemala
Acapulco, Mexico
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Pedro (Los Angeles), California
San Francisco, California
Victoria, British Columbia
Seattle, Washington

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Ports

Port Canaveral, Florida - Great Stirrup Cay (Cruise Line Private Island), Bahamas - Cartagena, Colombia - Panama Canal Transit - PANAMA CITY (COLON), PANAMA - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Acapulco, Mexico - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - San Francisco, California - Victoria, British Columbia - Seattle, Washington - View more ports

23 Night Panama Canal: Mexico & Bahamas (Port Canaveral To Seattle)

Norwegian Joy L

4.2

(869 Reviews)

2026 sail dates: Apr 11

$2049*

$89/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$2049*	$3079*	$4199*	$11679*
See Offers	$2029*	$3079*	$4109*	$4899*
See Offers	$2029*	$3079*	$4109*	$4899*
	$2029*	$3079*	$4109*	$4899*
See Offers	$2049*	$3079*	$4199*	$4899*
	$2029*	$3079*	$4109*	$4899*
See Offers	$2049*	$3079*	$4199*	$4899*
	$2061*	$3091*	$4211*	$4911*
See Offers	$2049*	$3079*	$4199*	$4899*
See Offers	$2049*	$3079*	$4199*	$4899*

Ports

Ft. Lauderdale (Port Everglades), Florida
George Town, Grand Cayman
Puerto Limon, Costa Rica
Panama Canal (Cruise Into Canal)
Colon, Panama
Oranjestad, Aruba
Willemstad, Curacao

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Ports

Ft. Lauderdale (Port Everglades), Florida - George Town, Grand Cayman - Puerto Limon, Costa Rica - Panama Canal (Cruise Into Canal) - Colon, Panama - Oranjestad, Aruba - Willemstad, Curacao - View more ports

12 Night Panama Canal With Costa Rica & Caribbean (Ft. Lauderdale Roundtrip)

Emerald Princess L

4.0

(1179 Reviews)

2024 sail dates: Dec 18

$717*

$60/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$717*	$927*	$1327*	$5338*
See Offers	$718*	$815*	$1328*	$2198*
See Offers	$718*	$815*	$1328*	$2198*
	$718*	$815*	$1328*	$2198*
See Offers	$718*	$907*	$1328*	$2198*
	$718*	$815*	$1328*	$2198*

Ports

Ft. Lauderdale (Port Everglades), Florida
Amber Cove (Puerto Plata), Dominican Republic
San Juan, Puerto Rico
Charlotte Amalie, St. Thomas
Half Moon Cay, Bahamas (Private Island)
Grand Turk Island
Oranjestad, Aruba
Cartagena, Colombia
Panama Canal Transit
Puntarenas, Costa Rica
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Diego, California
Catalina Island, California
Vancouver (Canada Place), British Columbia

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Ports

Ft. Lauderdale (Port Everglades), Florida - Amber Cove (Puerto Plata), Dominican Republic - San Juan, Puerto Rico - Charlotte Amalie, St. Thomas - Half Moon Cay, Bahamas (Private Island) - Grand Turk Island - Oranjestad, Aruba - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Diego, California - Catalina Island, California - Vancouver (Canada Place), British Columbia - View more ports

28 Night Eastern Caribbean & Panama Canal (Ft. Lauderdale To Vancouver)

Nieuw Amsterdam L

4.1

(775 Reviews)

2025 sail dates: Apr 06

$2269*

$81/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$2269*	$2649*	$4219*	$7929*
See Offers	$2269*	$2649*	$4219*	$7929*
See Offers	$2269*	$2649*	$4219*	$7929*
	$2269*	$2649*	$4219*	$7929*
See Offers	$2269*	$2649*	$4219*	$7929*
	$2269*	$2649*	$4219*	$7929*
See Offers	$2269*	$2649*	$4219*	$7929*
See Offers	$2269*	$2649*	$4219*	$7929*
	N/A	N/A	N/A	$7941*

Ports

Ft. Lauderdale (Port Everglades), Florida
Cartagena, Colombia
Panama Canal Transit
Puntarenas, Costa Rica
Puerto Quetzal, Guatemala
Huatulco, Mexico
Puerto Vallarta, Mexico
San Diego, California
Catalina Island, California
San Francisco, California
Vancouver (Canada Place), British Columbia
Seattle, Washington

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Ports

Ft. Lauderdale (Port Everglades), Florida - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Huatulco, Mexico - Puerto Vallarta, Mexico - San Diego, California - Catalina Island, California - San Francisco, California - Vancouver (Canada Place), British Columbia - Seattle, Washington - View more ports

21 Night Panama Canal (Ft. Lauderdale To Seattle)

Eurodam L

4.1

(1074 Reviews)

2025 sail dates: Apr 12

$1739*

$83/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1739*	$1939*	$3239*	$6589*
	$1739*	$1939*	$3239*	$6589*
See Offers	$1739*	$1939*	$3239*	$6589*
	$1739*	$1939*	$3239*	$6589*
See Offers	$1739*	$1939*	$3239*	$6589*
	$1739*	$1939*	$3239*	$6589*
See Offers	$1739*	$1939*	$3239*	$6589*
See Offers	$1739*	$1939*	$3239*	$6589*
	N/A	N/A	N/A	$6601*

Ports

Ft. Lauderdale (Port Everglades), Florida
Grand Turk Island
Oranjestad, Aruba
Cartagena, Colombia
Panama Canal Transit
Puerto Caldera, Costa Rica
Acajutla
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Diego, California
Victoria, British Columbia
Vancouver (Canada Place), British Columbia

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Grand Turk Island - Oranjestad, Aruba - Cartagena, Colombia - Panama Canal Transit - Puerto Caldera, Costa Rica - Acajutla - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Diego, California - Victoria, British Columbia - Vancouver (Canada Place), British Columbia - View more ports

21 Night Panama Canal (Ft. Lauderdale To Vancouver)

Nieuw Amsterdam L

4.1

(775 Reviews)

2025 sail dates: Apr 13

$1639*

$78/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1639*	$1839*	$3239*	$6239*
See Offers	$1639*	$1839*	$3239*	$6239*
See Offers	$1639*	$1839*	$3239*	$6239*
	$1639*	$1839*	$3239*	$6239*
See Offers	$1639*	$1839*	$3239*	$6239*
	$1639*	$1839*	$3239*	$6239*
See Offers	$1639*	$1839*	$3239*	$6239*
See Offers	$1639*	$1839*	$3239*	$6239*
	N/A	N/A	N/A	$6251*

Ports

San Diego, California
Puerto Vallarta, Mexico
Huatulco, Mexico
Puerto Chiapas (Tapachula), Mexico
Puerto Quetzal, Guatemala
Fuerte Amador, Panama
Panama Canal Transit
Cartagena, Colombia
Half Moon Cay, Bahamas (Private Island)
Miami, Florida

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Ports

San Diego, California - Puerto Vallarta, Mexico - Huatulco, Mexico - Puerto Chiapas (Tapachula), Mexico - Puerto Quetzal, Guatemala - Fuerte Amador, Panama - Panama Canal Transit - Cartagena, Colombia - Half Moon Cay, Bahamas (Private Island) - Miami, Florida - View more ports

15 Night Panama Canal (San Diego To Miami)

Zuiderdam M

4.0

(740 Reviews)

2026 sail dates: Feb 27

$1999*

$133/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1999*	$2299*	$3099*	$4299*
See Offers	$1999*	$2284*	$3072*	$4299*
See Offers	$1999*	$2284*	$3072*	$4299*
	$1999*	$2284*	$3072*	$4299*
See Offers	$1999*	$2299*	$3099*	$4299*
	$1999*	$2284*	$3072*	$4299*
See Offers	$1999*	$2299*	$3099*	$4299*
See Offers	$1999*	$2299*	$3099*	$4299*
	N/A	N/A	N/A	$4311*

Panama Canal, Central America cruises 325 Panama Canal, Central America Cruises Found

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