Panama Canal, Central America Cruises : Best Cruise Prices

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Ports

Miami, Florida
Cartagena, Colombia
Panama Canal Transit
Panama City, Panama
Puerto Quetzal, Guatemala
Acapulco, Mexico
Puerto Vallarta, Mexico
Mazatlan, Mexico
Cabo San Lucas, Mexico
San Pedro (Los Angeles), California

Ports

Miami, Florida - Cartagena, Colombia - Panama Canal Transit - Panama City, Panama - Puerto Quetzal, Guatemala - Acapulco, Mexico - Puerto Vallarta, Mexico - Mazatlan, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - View more ports

15 Night Panama Canal: Mexico & Colombia (Miami To Los Angeles)

Norwegian Joy L

4.2

(857 Reviews)

2024 sail dates: Nov 30

$969*

$65/night*

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Ports

Miami, Florida
Cartagena, Colombia
Panama Canal Transit
Panama City, Panama
Puerto Quetzal, Guatemala
Acapulco, Mexico
Puerto Vallarta, Mexico
Mazatlan, Mexico
Cabo San Lucas, Mexico
San Pedro (Los Angeles), California

View more ports

Ports

Miami, Florida - Cartagena, Colombia - Panama Canal Transit - Panama City, Panama - Puerto Quetzal, Guatemala - Acapulco, Mexico - Puerto Vallarta, Mexico - Mazatlan, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - View more ports

15 Night Panama Canal: Mexico & Colombia (Miami To Los Angeles)

Norwegian Joy L

4.2

(857 Reviews)

2024 sail dates: Nov 30

$969*

$65/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$969*	$1229*	$1699*	$5479*
See Offers	$969*	$1229*	$1699*	$1899*
See Offers	$969*	$1229*	$1699*	$1899*
See Offers	$969*	$1229*	$1699*	$1899*
See Offers	$969*	$1229*	$1699*	$1899*
See Offers	$969*	$1229*	$1699*	$1899*
	$981*	$1241*	$1711*	$1911*
	$969*	$1229*	$1699*	$1899*
See Offers	$969*	$1229*	$1699*	$1899*
See Offers	$969*	$1229*	$1699*	$1899*
See Offers	$969*	$1229*	$1699*	$1899*

Ports

Ft. Lauderdale (Port Everglades), Florida
Oranjestad, Aruba
Panama Canal Transit
Fuerte Amador, Panama
Puntarenas, Costa Rica
San Juan Del Sur, Nicaragua
Huatulco, Mexico
Puerto Vallarta, Mexico
San Pedro (Los Angeles), California

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Oranjestad, Aruba - Panama Canal Transit - Fuerte Amador, Panama - Puntarenas, Costa Rica - San Juan Del Sur, Nicaragua - Huatulco, Mexico - Puerto Vallarta, Mexico - San Pedro (Los Angeles), California - View more ports

16 Night Panama Canal - Ocean To Ocean (Ft. Lauderdale To Los Angeles)

Coral Princess M

4.1

(825 Reviews)

2025 sail dates: Feb 05, Mar 09, Apr 10

$1097*

$69/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1217*	$1477*	$2347*	N/A
See Offers	$1218*	$1393*	$2299*	$2622*
See Offers	$1218*	$1393*	$2299*	$2622*
See Offers	$1218*	$1393*	$2299*	$2622*
See Offers	$1218*	$1393*	$2299*	$2622*
	$1218*	$1393*	$2299*	$2622*
See Offers	$1218*	$1393*	$2299*	$2622*
See Offers	$1218*	$1393*	$2299*	$2622*
See Offers	$1218*	$1393*	$2299*	$2622*
	$1230*	$1405*	$2311*	$2634*
See Offers	$1218*	$1393*	$2299*	$2622*
	$1127*	$1397*	$1827*	N/A
See Offers	$1128*	$1289*	$1790*	$2597*
See Offers	$1128*	$1289*	$1790*	$2597*
See Offers	$1128*	$1289*	$1790*	$2597*
See Offers	$1128*	$1289*	$1790*	$2597*
	$1128*	$1289*	$1790*	$2597*
See Offers	$1128*	$1289*	$1790*	$2597*
See Offers	$1128*	$1289*	$1790*	$2597*
See Offers	$1128*	$1289*	$1790*	$2597*
	$1140*	$1301*	$1802*	$2609*
See Offers	$1128*	$1289*	$1790*	$2597*
	$1097*	$1557*	$2547*	N/A
See Offers	$1098*	$1255*	$2399*	$2614*
See Offers	$1098*	$1255*	$2548*	$2614*
See Offers	$1098*	$1255*	$2548*	$2614*
See Offers	$1098*	$1255*	$2548*	$2614*
	$1098*	$1255*	$2548*	$2614*
See Offers	$1098*	$1255*	$2548*	$2614*
See Offers	$1098*	$1255*	$2548*	$2614*
See Offers	$1098*	$1255*	$2548*	$2614*
	$1110*	$1267*	$2560*	$2626*
See Offers	$1098*	$1255*	$2548*	$2614*

Ports

Ft. Lauderdale (Port Everglades), Florida
Kralendijk, Bonaire
Oranjestad, Aruba
Cartagena, Colombia
Colon, Panama
Panama Canal (Cruise Into Canal)
Puerto Limon, Costa Rica
Ocho Rios, Jamaica

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Ports

Ft. Lauderdale (Port Everglades), Florida - Kralendijk, Bonaire - Oranjestad, Aruba - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - Ocho Rios, Jamaica - View more ports

12 Night Panama Canal With Costa Rica & Caribbean (Ft. Lauderdale Roundtrip)

Emerald Princess L

4.0

(1171 Reviews)

2025 sail dates: Feb 16

$827*

$69/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$827*	$1447*	$2027*	$4686*
See Offers	$828*	$953*	$1999*	$2499*
See Offers	$828*	$953*	$2028*	$2798*
See Offers	$828*	$953*	$2028*	$2798*
See Offers	$828*	$953*	$2028*	$2798*
	$828*	$953*	$2028*	$2798*
See Offers	$828*	$953*	$2028*	$2798*
See Offers	$828*	$953*	$2028*	$2798*
See Offers	$828*	$953*	$2028*	$2798*
	$840*	$965*	$2040*	$2810*
See Offers	$828*	$953*	$2028*	$2798*

Ports

San Pedro (Los Angeles), California
Puerto Vallarta, Mexico
Huatulco, Mexico
San Juan Del Sur, Nicaragua
Puntarenas, Costa Rica
PANAMA CITY (FUERTE AMADOR), PANAMA
Panama Canal Transit
Oranjestad, Aruba
Ft. Lauderdale (Port Everglades), Florida

View more ports

Ports

San Pedro (Los Angeles), California - Puerto Vallarta, Mexico - Huatulco, Mexico - San Juan Del Sur, Nicaragua - Puntarenas, Costa Rica - PANAMA CITY (FUERTE AMADOR), PANAMA - Panama Canal Transit - Oranjestad, Aruba - Ft. Lauderdale (Port Everglades), Florida - View more ports

16 Night Panama Canal - Ocean To Ocean (Los Angeles To Ft. Lauderdale)

Coral Princess M

4.1

(825 Reviews)

2025 sail dates: Feb 21, Mar 25, Oct 28

$1097*

$69/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1227*	$1427*	$2297*	N/A
See Offers	$1228*	$1404*	$2250*	$2832*
See Offers	$1228*	$1404*	$2250*	$2832*
See Offers	$1228*	$1404*	$2250*	$2832*
See Offers	$1228*	$1404*	$2250*	$2832*
	$1228*	$1404*	$2250*	$2832*
See Offers	$1228*	$1404*	$2250*	$2832*
See Offers	$1228*	$1404*	$2250*	$2832*
See Offers	$1228*	$1404*	$2250*	$2832*
	$1240*	$1416*	$2262*	$2844*
See Offers	$1228*	$1404*	$2250*	$2832*
	$1097*	$1347*	$1847*	$5198*
See Offers	$1098*	$1348*	$1809*	$2513*
See Offers	$1098*	$1348*	$1809*	$2513*
See Offers	$1098*	$1348*	$1809*	$2513*
See Offers	$1098*	$1348*	$1809*	$2513*
	$1098*	$1348*	$1809*	$2513*
See Offers	$1098*	$1255*	$1809*	$2513*
See Offers	$1098*	$1255*	$1809*	$2513*
See Offers	$1098*	$1255*	$1809*	$2513*
	$1110*	$1267*	$1821*	$2525*
See Offers	$1098*	$1255*	$1809*	$2513*
	$1197*	$1497*	$2097*	$5398*
See Offers	$1198*	$1369*	$2054*	$2408*
See Offers	$1198*	$1369*	$2054*	$2408*
See Offers	$1198*	$1369*	$2054*	$2408*
	$1198*	$1369*	$2054*	$2408*
See Offers	$1198*	$1369*	$2054*	$2408*
See Offers	$1198*	$1369*	$2054*	$2408*
See Offers	$1198*	$1369*	$2054*	$2408*
	$1210*	$1381*	$2066*	$2420*
See Offers	$1198*	$1369*	$2054*	$2408*

Ports

Ft. Lauderdale (Port Everglades), Florida
George Town, Grand Cayman
Cartagena, Colombia
Colon, Panama
Panama Canal Transit
Puerto Quetzal, Guatemala
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Pedro (Los Angeles), California

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - George Town, Grand Cayman - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Puerto Quetzal, Guatemala - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - View more ports

16 Night Panama Canal Westward (Ft. Lauderdale To Los Angeles)

Serenade of the Seas L

4.1

(1781 Reviews)

2025 sail dates: Apr 13

$1309*

$82/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1309*	$1429*	$2624*	$10627*
See Offers	$1309*	$1429*	$2624*	$10627*
See Offers	$1309*	$1428*	$2529*	N/A
	$1321*	$1441*	$2636*	$10639*
See Offers	$1309*	$1428*	$2529*	N/A
See Offers	$1309*	$1428*	$2529*	N/A
	$1309*	$1428*	$2529*	N/A
See Offers	$1309*	$1429*	$2624*	$10627*
See Offers	$1309*	$1388*	$2624*	$10627*
See Offers	$1309*	$1388*	$2624*	$10627*

Ports

Ft. Lauderdale (Port Everglades), Florida
George Town, Grand Cayman
Falmouth, Jamaica
Puerto Limon, Costa Rica
Panama Canal (Cruise Into Canal)
Colon, Panama
Oranjestad, Aruba
Willemstad, Curacao

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - George Town, Grand Cayman - Falmouth, Jamaica - Puerto Limon, Costa Rica - Panama Canal (Cruise Into Canal) - Colon, Panama - Oranjestad, Aruba - Willemstad, Curacao - View more ports

12 Night Panama Canal With Costa Rica & Caribbean (Ft. Lauderdale Roundtrip)

Caribbean Princess L

3.9

(1869 Reviews)

2025 sail dates: Nov 29

2026 sail dates: Feb 21

$747*

$62/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$747*	$1047*	$1497*	$4098*
See Offers	$748*	$785*	$1498*	$2098*
See Offers	$748*	$785*	$1498*	$2098*
See Offers	$748*	$785*	$1498*	$2098*
	$748*	$785*	$1498*	$2098*
See Offers	$748*	$785*	$1498*	$2098*
See Offers	$748*	$785*	$1498*	$2098*
See Offers	$748*	$785*	$1498*	$2098*
	$760*	$797*	$1510*	$2110*
See Offers	$748*	$785*	$1498*	$2098*
	$1097*	$1547*	$1997*	$4498*
See Offers	$1098*	$1148*	$1998*	$2498*
See Offers	$1098*	$1148*	$1998*	$2498*
See Offers	$1098*	$1148*	$1998*	$2498*
	$1098*	$1148*	$1998*	$2498*
See Offers	$1098*	$1148*	$1998*	$2498*
See Offers	$1098*	$1148*	$1998*	$2498*
See Offers	$1098*	$1148*	$1998*	$2498*
	$1110*	$1160*	$2010*	$2510*
See Offers	$1098*	$1148*	$1998*	$2498*

Ports

Ft. Lauderdale (Port Everglades), Florida
Oranjestad, Aruba
Willemstad, Curacao
Cartagena, Colombia
Panama Canal (Cruise Into Canal)
Cristobal, Panama
Puerto Limon, Costa Rica
George Town, Grand Cayman

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Oranjestad, Aruba - Willemstad, Curacao - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Cristobal, Panama - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports

12 Night Panama Canal With Costa Rica & Caribbean (Ft. Lauderdale Roundtrip)

Emerald Princess L

4.0

(1171 Reviews)

2025 sail dates: Feb 04

$747*

$62/night*

Inside

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$747*	$1277*	$1747*	$4817*
See Offers	$748*	$860*	$1748*	$2298*
See Offers	$748*	$860*	$1748*	$2298*
See Offers	$748*	$860*	$1748*	$2298*
See Offers	$748*	$860*	$1748*	$2298*
	$748*	$860*	$1748*	$2298*
See Offers	$674*	$774*	$1574*	$2069*
See Offers	$674*	$774*	$1574*	$2069*
See Offers	$674*	$774*	$1574*	$2069*
	$686*	$786*	$1586*	$2081*
See Offers	$674*	$774*	$1574*	$2069*

Ports

Ft. Lauderdale (Port Everglades), Florida
Oranjestad, Aruba
Panama Canal Transit
PANAMA CITY (FUERTE AMADOR), PANAMA
Puntarenas, Costa Rica
San Juan Del Sur, Nicaragua
Huatulco, Mexico
Puerto Vallarta, Mexico
San Pedro (Los Angeles), California

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Oranjestad, Aruba - Panama Canal Transit - PANAMA CITY (FUERTE AMADOR), PANAMA - Puntarenas, Costa Rica - San Juan Del Sur, Nicaragua - Huatulco, Mexico - Puerto Vallarta, Mexico - San Pedro (Los Angeles), California - View more ports

16 Night Panama Canal - Ocean To Ocean (Ft. Lauderdale To Los Angeles)

Emerald Princess L

4.0

(1171 Reviews)

2025 sail dates: Nov 02

$1197*

$75/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1197*	$1497*	$2197*	$5498*
See Offers	$1198*	$1369*	$2198*	$3398*
See Offers	$1198*	$1369*	$2198*	$3398*
See Offers	$1198*	$1369*	$2198*	$3398*
	$1198*	$1369*	$2198*	$3398*
See Offers	$1198*	$1369*	$2198*	$2711*
See Offers	$1198*	$1369*	$2198*	$2711*
See Offers	$1198*	$1369*	$2198*	$2711*
	$1210*	$1381*	$2210*	$2723*
See Offers	$1198*	$1369*	$2198*	$2711*

Ports

San Diego, California
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
Huatulco, Mexico
Puerto Chiapas (Tapachula), Mexico
Puerto Quetzal, Guatemala
Puntarenas, Costa Rica
Panama Canal Transit
Oranjestad, Aruba
Ft. Lauderdale (Port Everglades), Florida

View more ports

Ports

San Diego, California - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - Huatulco, Mexico - Puerto Chiapas (Tapachula), Mexico - Puerto Quetzal, Guatemala - Puntarenas, Costa Rica - Panama Canal Transit - Oranjestad, Aruba - Ft. Lauderdale (Port Everglades), Florida - View more ports

16 Night Panama Canal (San Diego To Ft. Lauderdale)

Nieuw Amsterdam L

4.1

(775 Reviews)

2024 sail dates: Oct 04

$1349*

$84/night*

Inside

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1349*	$1599*	$2864*	$6464*
See Offers	$1349*	$1599*	$2864*	$5849*
See Offers	$1349*	$1599*	$2864*	$6464*
See Offers	$1349*	$1599*	$2864*	$6464*
See Offers	$1349*	$1599*	$2864*	$6464*
	$1349*	$1599*	$2864*	$6464*
See Offers	$1349*	$1599*	$2864*	$6464*
See Offers	$1349*	$1599*	$2864*	$5849*
See Offers	$1349*	$1599*	$2864*	$5849*
	$1361*	$1611*	$2876*	$6476*

Ports

Seattle, Washington
Vancouver (Canada Place), British Columbia
Santa Barbara, California
San Diego, California
Puerto Vallarta, Mexico
Huatulco, Mexico
Puerto Chiapas (Tapachula), Mexico
Puerto Quetzal, Guatemala
Puntarenas, Costa Rica
Panama Canal Transit
Oranjestad, Aruba
Ft. Lauderdale (Port Everglades), Florida

View more ports

Ports

Seattle, Washington - Vancouver (Canada Place), British Columbia - Santa Barbara, California - San Diego, California - Puerto Vallarta, Mexico - Huatulco, Mexico - Puerto Chiapas (Tapachula), Mexico - Puerto Quetzal, Guatemala - Puntarenas, Costa Rica - Panama Canal Transit - Oranjestad, Aruba - Ft. Lauderdale (Port Everglades), Florida - View more ports

21 Night Panama Canal - Eastbound (Seattle To Ft. Lauderdale)

Eurodam L

4.1

(1072 Reviews)

2024 sail dates: Oct 05

$1389*

$66/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1389*	$1689*	$2789*	$5839*
See Offers	$1389*	$1689*	$2789*	$5839*
See Offers	$1389*	$1689*	$2789*	$5839*
See Offers	$1389*	$1689*	$2789*	$5839*
See Offers	$1389*	$1689*	$2789*	$5839*
	$1389*	$1689*	$2789*	$5839*
See Offers	$1250*	$1520*	$2649*	$5547*
See Offers	$1250*	$1520*	$2649*	$5547*
See Offers	$1250*	$1520*	$2649*	$5547*
	$1262*	$1532*	$2661*	$5559*

Panama Canal, Central America cruises 325 Panama Canal, Central America Cruises Found

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