Panama Canal, Central America Cruises : Best Cruise Prices

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Ports

New York, New York
Ft. Lauderdale (Port Everglades), Florida
Philipsburg, St. Maarten
Castries, St. Lucia
Bridgetown, Barbados
Devils Island, French Guiana
Cruise Amazon River
CRUISE BARRA NORTE RIVER
Macapa, Brazil
Cross The Equator
Santarem, Brazil
Boca Da Valeria, Brazil
Manaus, Brazil
Parintins, Brazil
Alter Do Chao, Brazil
Port of Spain
Willemstad, Curacao
Oranjestad, Aruba

Ports

New York, New York - Ft. Lauderdale (Port Everglades), Florida - Philipsburg, St. Maarten - Castries, St. Lucia - Bridgetown, Barbados - Devils Island, French Guiana - Cruise Amazon River - CRUISE BARRA NORTE RIVER - Macapa, Brazil - Cross The Equator - Santarem, Brazil - Boca Da Valeria, Brazil - Manaus, Brazil - Parintins, Brazil - Alter Do Chao, Brazil - Port of Spain - Willemstad, Curacao - Oranjestad, Aruba - View more ports

30 Night Amazon Explorer (New York To Ft. Lauderdale)

Volendam M

4.0

(296 Reviews)

2025 sail dates: Nov 21

$5284*

$176/night*

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Sponsored cruise

Ports

Miami, Florida
George Town, Grand Cayman
Cartagena, Colombia
Panama Canal (Cruise Into Canal)
Colon, Panama
Puerto Limon, Costa Rica
Harvest Caye, Belize
Cozumel, Mexico

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Ports

Miami, Florida - George Town, Grand Cayman - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - Harvest Caye, Belize - Cozumel, Mexico - View more ports

11 Night Panama Canal: Mexico Costa Rica & Belize (Miami Roundtrip)

Norwegian Gem L

3.8

(2493 Reviews)

2025 sail dates: Jan 03

$1091*

$99/night*

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Ports

Ft. Lauderdale (Port Everglades), Florida
Willemstad, Curacao
Kralendijk, Bonaire
Oranjestad, Aruba
Half Moon Cay, Bahamas (Private Island)
Colon, Panama
Panama Canal (Cruise Into Canal)
Puerto Limon, Costa Rica
Falmouth, Jamaica
George Town, Grand Cayman

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Ports

Ft. Lauderdale (Port Everglades), Florida - Willemstad, Curacao - Kralendijk, Bonaire - Oranjestad, Aruba - Half Moon Cay, Bahamas (Private Island) - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - Falmouth, Jamaica - George Town, Grand Cayman - View more ports

21 Night Southern Caribbean & Panama Canal: Abc Islands (Ft. Lauderdale Roundtrip)

Rotterdam L

4.4

(256 Reviews)

2026 sail dates: Jan 09

$2404*

$114/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$2404*	$3124*	$3424*	$5254*
See Offers	$2664*	$3384*	$3684*	$5514*
See Offers	$2664*	$3384*	$3684*	$5514*
	$2664*	$3384*	$3684*	$5514*
See Offers	$2664*	$3384*	$3684*	$5514*
	N/A	N/A	N/A	$5489*
See Offers	$2664*	$3384*	$3684*	$5514*
See Offers	$2664*	$3384*	$3684*	$5514*

Ports

San Pedro (Los Angeles), California
Puerto Vallarta, Mexico
Huatulco, Mexico
Puerto Chiapas (Tapachula), Mexico
Puntarenas, Costa Rica
PANAMA CITY (FUERTE AMADOR), PANAMA
Panama Canal Transit
Oranjestad, Aruba
Ft. Lauderdale (Port Everglades), Florida

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Ports

San Pedro (Los Angeles), California - Puerto Vallarta, Mexico - Huatulco, Mexico - Puerto Chiapas (Tapachula), Mexico - Puntarenas, Costa Rica - PANAMA CITY (FUERTE AMADOR), PANAMA - Panama Canal Transit - Oranjestad, Aruba - Ft. Lauderdale (Port Everglades), Florida - View more ports

16 Night Panama Canal - Ocean To Ocean (Los Angeles To Ft. Lauderdale)

Island Princess M

4.0

(908 Reviews)

2026 sail dates: Oct 25, Nov 26

2027 sail dates: Mar 02, Apr 03

$1349*

$84/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1449*	$1749*	$2799*	$5849*
See Offers	$1449*	$1599*	$2669*	$3219*
	$1449*	$1599*	$2669*	$3219*
See Offers	$1449*	$1599*	$2669*	$3219*
	$1449*	$1599*	$2669*	$3219*
See Offers	$1449*	$1599*	$2669*	$3219*
See Offers	$1449*	$1599*	$2669*	$3219*
	$1349*	$1499*	$2399*	$5249*
See Offers	$1349*	$1479*	$2299*	$2739*
	$1349*	$1479*	$2299*	$2739*
See Offers	$1349*	$1479*	$2299*	$2739*
	$1349*	$1479*	$2299*	$2739*
See Offers	$1349*	$1479*	$2299*	$2739*
See Offers	$1349*	$1479*	$2299*	$2739*
	$1399*	$1699*	$2699*	$5699*
See Offers	$1399*	$1549*	$2579*	$3109*
	$1399*	$1549*	$2579*	$3109*
See Offers	$1399*	$1549*	$2579*	$3109*
	$1399*	$1699*	$2699*	$5699*
See Offers	$1399*	$1549*	$2579*	$3099*
	$1399*	$1549*	$2579*	$3099*
See Offers	$1399*	$1549*	$2579*	$3099*

Ports

San Pedro (Los Angeles), California
Cabo San Lucas, Mexico
Mazatlan, Mexico
Puerto Vallarta, Mexico
Puerto Quetzal, Guatemala
Puerto Caldera, Costa Rica
Panama Canal Transit
Colon, Panama
Cartagena, Colombia
Miami, Florida

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Ports

San Pedro (Los Angeles), California - Cabo San Lucas, Mexico - Mazatlan, Mexico - Puerto Vallarta, Mexico - Puerto Quetzal, Guatemala - Puerto Caldera, Costa Rica - Panama Canal Transit - Colon, Panama - Cartagena, Colombia - Miami, Florida - View more ports

16 Night Panama Canal: Mexico & Colombia (Los Angeles To Miami)

Norwegian Joy L

4.2

(944 Reviews)

2025 sail dates: Jan 05

$1204*

$75/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1204*	$1654*	$1704*	$4954*
See Offers	$1204*	$1654*	$1704*	$1884*
	$1204*	$1654*	$1704*	$1884*
See Offers	$1204*	$1654*	$1704*	$1884*
See Offers	$1204*	$1654*	$1704*	$1884*
See Offers	$1204*	$1654*	$1704*	$1884*
See Offers	$1204*	$1654*	$1704*	$1884*
See Offers	$1204*	$1654*	$1704*	$1884*
See Offers	$1204*	$1654*	$1704*	$1884*

Ports

Miami, Florida
Cartagena, Colombia
Panama Canal Transit
Panama City, Panama
Puntarenas, Costa Rica
Puerto Quetzal, Guatemala
Acapulco, Mexico
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Pedro (Los Angeles), California
San Francisco, California
Victoria, British Columbia
Seattle, Washington

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Ports

Miami, Florida - Cartagena, Colombia - Panama Canal Transit - Panama City, Panama - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Acapulco, Mexico - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - San Francisco, California - Victoria, British Columbia - Seattle, Washington - View more ports

22 Night Panama Canal: Mexico & Costa Rica (Miami To Seattle)

Norwegian Encore XL

4.3

(691 Reviews)

2026 sail dates: Apr 11

$2929*

$133/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$2929*	$3819*	$4789*	$12379*
See Offers	$2873*	$3819*	$4673*	$5473*
	$2873*	$3819*	$4673*	$5473*
See Offers	$2929*	$3819*	$4789*	$5479*
See Offers	$2873*	$3819*	$4673*	$5473*
See Offers	$2873*	$3819*	$4673*	$5473*
See Offers	$2929*	$3819*	$4789*	$5479*
See Offers	$2929*	$3819*	$4789*	$5479*
See Offers	$2929*	$3819*	$4789*	$5479*

Ports

Tampa, Florida
George Town, Grand Cayman
Cartagena, Colombia
Panama Canal Transit
Puntarenas, Costa Rica
Cabo San Lucas, Mexico
Seattle, Washington

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Ports

Tampa, Florida - George Town, Grand Cayman - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Cabo San Lucas, Mexico - Seattle, Washington - View more ports

16 Night Carnival Journeys: Panama Canal Westbound (Tampa To Seattle)

Carnival Miracle L

4.0

(2755 Reviews)

2026 sail dates: Apr 11

$1599*

$100/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1599*	$1799*	$2169*	$4303*
	$1599*	$1799*	$2169*	$4303*
See Offers	$1599*	$1799*	$2169*	$4303*
	$1591*	$1791*	$2161*	$4295*
See Offers	$1599*	$1799*	$2169*	$4303*

Ports

Seattle, Washington
Cabo San Lucas, Mexico
Puntarenas, Costa Rica
Panama Canal Transit
Cartagena, Colombia
Galveston, Texas

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Ports

Seattle, Washington - Cabo San Lucas, Mexico - Puntarenas, Costa Rica - Panama Canal Transit - Cartagena, Colombia - Galveston, Texas - View more ports

16 Night Panama Canal: Carnival Journeys (Seattle To Galveston)

Carnival Miracle L

4.0

(2755 Reviews)

2026 sail dates: Sep 26

$1559*

$97/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1559*	$1919*	$2379*	$3643*
	$1559*	$1919*	$2379*	$3643*
See Offers	$1559*	$1919*	$2379*	$3643*
	$1551*	$1911*	$2371*	$3635*
See Offers	$1559*	$1919*	$2379*	$3643*

Ports

Miami, Florida
Great Stirrup Cay (Cruise Line Private Island), Bahamas
Cartagena, Colombia
Colon, Panama
Cruise Gatun Lake (Inside Panama Canal)
Puerto Limon, Costa Rica
Falmouth, Jamaica
George Town, Grand Cayman

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Ports

Miami, Florida - Great Stirrup Cay (Cruise Line Private Island), Bahamas - Cartagena, Colombia - Colon, Panama - Cruise Gatun Lake (Inside Panama Canal) - Puerto Limon, Costa Rica - Falmouth, Jamaica - George Town, Grand Cayman - View more ports

11 Night Panama Canal Partial Transit: Mexico Jamaica & Costa Rica (Miami Roundtrip)

Norwegian Sun M

3.7

(2010 Reviews)

2026 sail dates: Nov 18, Nov 29

$1561*

$142/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1981*	$2431*	$3481*	$7831*
See Offers	$1981*	$2431*	$3481*	$4481*
	$1981*	$2431*	$3481*	$4481*
See Offers	$1981*	$2431*	$3481*	$4481*
See Offers	$1981*	$2431*	$3481*	$4481*
See Offers	$1981*	$2431*	$3481*	$4481*
See Offers	$1981*	$2431*	$3481*	$4481*
See Offers	$1981*	$2431*	$3481*	$4481*
See Offers	$1981*	$2431*	$3481*	$4481*
See Offers	$1561*	$2011*	$3061*	$7411*
See Offers	$1561*	$2011*	$3061*	$4061*
	$1561*	$2011*	$3061*	$4061*
See Offers	$1561*	$2011*	$3061*	$4061*
See Offers	$1561*	$2011*	$3061*	$4061*
See Offers	$1561*	$2011*	$3061*	$4061*
See Offers	$1561*	$2011*	$3061*	$4061*
See Offers	$1561*	$2011*	$3061*	$4061*
See Offers	$1561*	$2011*	$3061*	$4061*

Ports

San Pedro (Los Angeles), California
Cabo San Lucas, Mexico
Puerto Vallarta, Mexico
Puerto Quetzal, Guatemala
Puerto Caldera, Costa Rica
Panama City, Panama
Panama Canal Transit
Cartagena, Colombia
Miami, Florida

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Ports

San Pedro (Los Angeles), California - Cabo San Lucas, Mexico - Puerto Vallarta, Mexico - Puerto Quetzal, Guatemala - Puerto Caldera, Costa Rica - Panama City, Panama - Panama Canal Transit - Cartagena, Colombia - Miami, Florida - View more ports

15 Night Panama Canal: Mexico & Colombia (Los Angeles To Miami)

Norwegian Joy L

4.2

(944 Reviews)

2025 sail dates: Feb 06

$1386*

$92/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1386*	$1786*	$1906*	$4786*
See Offers	$1386*	$1886*	$1906*	$2106*
	$1386*	$1886*	$1906*	$2106*
See Offers	$1269*	$1609*	$1711*	$1881*
See Offers	$1386*	$1886*	$1906*	$2106*
See Offers	$1386*	$1886*	$1906*	$2106*
See Offers	$1386*	$1786*	$1906*	$2106*
See Offers	$1269*	$1609*	$1711*	$1881*
See Offers	$1386*	$1786*	$1906*	$2106*

Ports

San Pedro (Los Angeles), California
Cabo San Lucas, Mexico
Puerto Vallarta, Mexico
Manzanillo, Mexico
Acapulco, Mexico
Puerto Quetzal, Guatemala
Puntarenas, Costa Rica
Panama City, Panama
Panama Canal Transit
Cartagena, Colombia
Miami, Florida

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Ports

San Pedro (Los Angeles), California - Cabo San Lucas, Mexico - Puerto Vallarta, Mexico - Manzanillo, Mexico - Acapulco, Mexico - Puerto Quetzal, Guatemala - Puntarenas, Costa Rica - Panama City, Panama - Panama Canal Transit - Cartagena, Colombia - Miami, Florida - View more ports

16 Night Panama Canal: Mexico & Colombia (Los Angeles To Miami)

Norwegian Encore XL

4.3

(691 Reviews)

2025 sail dates: Oct 23

$2123*

$133/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$2123*	$2793*	$3433*	$11163*
See Offers	$2123*	$2793*	$3433*	$3983*
	$2123*	$2793*	$3433*	$3983*
See Offers	$2123*	$2793*	$3433*	$3983*
See Offers	$2123*	$2793*	$3433*	$3983*
See Offers	$2123*	$2793*	$3433*	$3983*
See Offers	$2123*	$2793*	$3433*	$3983*
See Offers	$2123*	$2793*	$3433*	$3983*
See Offers	$2123*	$2793*	$3433*	$3983*

Ports

San Pedro (Los Angeles), California
Puerto Vallarta, Mexico
Huatulco, Mexico
San Juan Del Sur, Nicaragua
Puntarenas, Costa Rica
PANAMA CITY (FUERTE AMADOR), PANAMA
Panama Canal Transit
Oranjestad, Aruba
Ft. Lauderdale (Port Everglades), Florida

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Ports

San Pedro (Los Angeles), California - Puerto Vallarta, Mexico - Huatulco, Mexico - San Juan Del Sur, Nicaragua - Puntarenas, Costa Rica - PANAMA CITY (FUERTE AMADOR), PANAMA - Panama Canal Transit - Oranjestad, Aruba - Ft. Lauderdale (Port Everglades), Florida - View more ports

16 Night Panama Canal - Ocean To Ocean (Los Angeles To Ft. Lauderdale)

Island Princess M

4.0

(908 Reviews)

2026 sail dates: Jan 08, Feb 09

$1808*

$113/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1808*	$2278*	$2678*	$6269*
See Offers	$1809*	$1986*	$2635*	$3125*
	$1809*	$1986*	$2635*	$3125*
See Offers	$1808*	$1985*	$2635*	$3125*
See Offers	$1808*	$1985*	$2635*	$3125*
See Offers	$1808*	$1985*	$2635*	$3125*
See Offers	$1809*	$1986*	$2635*	$3125*
	$1978*	$2448*	$2898*	$6389*
See Offers	$1978*	$2176*	$2851*	$3364*
	$1978*	$2176*	$2851*	$3364*
See Offers	$1978*	$2176*	$2851*	$3364*
See Offers	$1978*	$2176*	$2851*	$3364*
See Offers	$1978*	$2176*	$2851*	$3364*
See Offers	$1978*	$2176*	$2851*	$3364*

Panama Canal, Central America cruises 387 Panama Canal, Central America Cruises Found

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