Panama Canal, Central America Cruises : Best Cruise Prices

Ports

San Diego, California
Puerto Vallarta, Mexico
Huatulco, Mexico
Puerto Chiapas (Tapachula), Mexico
Puerto Quetzal, Guatemala
Acajutla
Puntarenas, Costa Rica
Panama Canal Transit
Oranjestad, Aruba
Ft. Lauderdale (Port Everglades), Florida
Grand Turk Island
San Juan, Puerto Rico
Charlotte Amalie, St. Thomas
Half Moon Cay, Bahamas (Private Island)

Ports

San Diego, California - Puerto Vallarta, Mexico - Huatulco, Mexico - Puerto Chiapas (Tapachula), Mexico - Puerto Quetzal, Guatemala - Acajutla - Puntarenas, Costa Rica - Panama Canal Transit - Oranjestad, Aruba - Ft. Lauderdale (Port Everglades), Florida - Grand Turk Island - San Juan, Puerto Rico - Charlotte Amalie, St. Thomas - Half Moon Cay, Bahamas (Private Island) - View more ports

24 Night Panama Canal & Eastern Caribbean (San Diego To Ft. Lauderdale)

Eurodam L

4.1

(1102 Reviews)

2025 sail dates: Oct 09

$2543*

$106/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$2543*	$2818*	$4168*	$7283*
See Offers	$2543*	$2818*	$4168*	$7283*
See Offers	$2543*	$2818*	$4168*	$7283*
	$2543*	$2818*	$4168*	$7283*
See Offers	$2543*	$2818*	$4168*	$7283*
See Offers	$2543*	$2818*	$4168*	$7283*
See Offers	$2543*	$2818*	$4168*	$7283*
	$2543*	$2818*	$4168*	$7283*
See Offers	$2543*	$2818*	$4168*	$7283*

Ports

Ft. Lauderdale (Port Everglades), Florida
Grand Turk Island
Oranjestad, Aruba
Cartagena, Colombia
Panama Canal Transit
Puerto Caldera, Costa Rica
Acajutla
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Diego, California
Victoria, British Columbia
Vancouver (Canada Place), British Columbia

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Ports

Ft. Lauderdale (Port Everglades), Florida - Grand Turk Island - Oranjestad, Aruba - Cartagena, Colombia - Panama Canal Transit - Puerto Caldera, Costa Rica - Acajutla - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Diego, California - Victoria, British Columbia - Vancouver (Canada Place), British Columbia - View more ports

21 Night Panama Canal (Ft. Lauderdale To Vancouver)

Nieuw Amsterdam L

4.1

(793 Reviews)

2025 sail dates: Apr 13

$2039*

$97/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$2039*	$2239*	$3739*	$6539*
See Offers	$2144*	$2344*	$3844*	$6644*
See Offers	$2039*	$2239*	$3739*	$6539*
	$2144*	$2344*	$3844*	$6644*
See Offers	$2039*	$2239*	$3739*	$6539*
See Offers	$2144*	$2344*	$3844*	$6644*
See Offers	$2039*	$2239*	$3739*	$6539*
	$2039*	$2239*	$3739*	$6539*
See Offers	$2039*	$2239*	$3739*	$6539*

Ports

Miami, Florida
Ocho Rios, Jamaica
Cartagena, Colombia
Cruise Gatun Lake And Panama Canal
Colon, Panama
Puerto Limon, Costa Rica
Harvest Caye, Belize
Cozumel, Mexico

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Ports

Miami, Florida - Ocho Rios, Jamaica - Cartagena, Colombia - Cruise Gatun Lake And Panama Canal - Colon, Panama - Puerto Limon, Costa Rica - Harvest Caye, Belize - Cozumel, Mexico - View more ports

11 Night Panama Canal: Mexico Costa Rica & Belize (Miami Roundtrip)

Norwegian Pearl L

3.8

(2053 Reviews)

2025 sail dates: Dec 22

2026 sail dates: Jan 02

$1736*

$158/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$2199*	$2489*	$4079*	$14509*
See Offers	$2169*	$2489*	$3889*	$4459*
See Offers	$2199*	$2489*	$4079*	$4459*
	$2169*	$2489*	$3889*	$4459*
See Offers	$2169*	$2489*	$3889*	$4459*
See Offers	$2199*	$2489*	$4079*	$4459*
See Offers	$2169*	$2489*	$3889*	$4459*
See Offers	$2199*	$2489*	$4079*	$4459*
	$2198*	$2488*	$4078*	$4458*
See Offers	$2199*	$2489*	$4079*	$4459*
See Offers	$1736*	$2086*	$3256*	$8136*
See Offers	$1736*	$2086*	$3189*	$3336*
See Offers	$1736*	$2086*	$3256*	$3336*
	$1736*	$2086*	$3189*	$3336*
See Offers	$1736*	$2086*	$3189*	$3336*
See Offers	$1736*	$2086*	$3256*	$3336*
See Offers	$1736*	$2086*	$3189*	$3336*
See Offers	$1736*	$2086*	$3256*	$3336*
	$1735*	$2085*	$3255*	$3335*
See Offers	$1736*	$2086*	$3256*	$3336*

Ports

Ft. Lauderdale (Port Everglades), Florida
Half Moon Cay, Bahamas (Private Island)
Oranjestad, Aruba
Cartagena, Colombia
Colon, Panama
Panama Canal (Cruise Into Canal)
Puerto Limon, Costa Rica
Falmouth, Jamaica

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Ports

Ft. Lauderdale (Port Everglades), Florida - Half Moon Cay, Bahamas (Private Island) - Oranjestad, Aruba - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - Falmouth, Jamaica - View more ports

12 Night Panama Canal Discovery: Costa Rica & Greater Antilles (Ft. Lauderdale Roundtrip)

Rotterdam L

4.4

(266 Reviews)

2025 sail dates: Nov 16

$1319*

$110/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1319*	$1919*	$2119*	$3419*
See Offers	$1319*	$1919*	$2119*	$3419*
See Offers	$1319*	$1919*	$2119*	$3419*
	$1319*	$1919*	$2119*	$3419*
See Offers	$1319*	$1919*	$2119*	$3419*
See Offers	$1319*	$1919*	$2119*	$3419*
See Offers	$1319*	$1919*	$2119*	$3419*
	$1319*	$1919*	$2119*	$3419*
See Offers	$1319*	$1919*	$2119*	$3419*

Ports

Ft. Lauderdale (Port Everglades), Florida
George Town, Grand Cayman
Panama Canal Transit
Fuerte Amador, Panama
Cross The Equator
Manta, Ecuador
Salaverry (Trujillo), Peru
Callao (Lima), Peru
General San Martin (Pisco), Peru
Coquimbo (La Serena), Chile
San Antonio, Chile
Puerto Montt, Chile
Puerto Chacabuco, Chile
Cruise Chilean Fjords
Cruise Canal Sarmiento
Cruise Cockburn & Beagle Channels
Punta Arenas, Chile
Cruise Strait Of Magellan
Cruise Glacier Alley
Ushuaia, Tierra Del Fuego, Argentina
Cruise Cape Horn
Port Stanley, Falkland Islands
Montevideo, Uruguay
Buenos Aires, Argentina

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Ports

Ft. Lauderdale (Port Everglades), Florida - George Town, Grand Cayman - Panama Canal Transit - Fuerte Amador, Panama - Cross The Equator - Manta, Ecuador - Salaverry (Trujillo), Peru - Callao (Lima), Peru - General San Martin (Pisco), Peru - Coquimbo (La Serena), Chile - San Antonio, Chile - Puerto Montt, Chile - Puerto Chacabuco, Chile - Cruise Chilean Fjords - Cruise Canal Sarmiento - Cruise Cockburn & Beagle Channels - Punta Arenas, Chile - Cruise Strait Of Magellan - Cruise Glacier Alley - Ushuaia, Tierra Del Fuego, Argentina - Cruise Cape Horn - Port Stanley, Falkland Islands - Montevideo, Uruguay - Buenos Aires, Argentina - View more ports

31 Night Panama Canal Inca & South America Discovery (Ft. Lauderdale To Buenos Aires)

Oosterdam M

4.1

(890 Reviews)

2025 sail dates: Nov 17

$3834*

$124/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$3834*	$4034*	$5844*	$8444*
See Offers	$3834*	$4034*	$5844*	$8444*
See Offers	$3834*	$4034*	$5844*	$8444*
	$3834*	$4034*	$5844*	$8444*
See Offers	$3834*	$4034*	$5844*	$8444*
See Offers	$3834*	$4034*	$5844*	$8444*
See Offers	$3834*	$4034*	$5844*	$8444*
	$3834*	$4034*	$5844*	$8444*
See Offers	$3834*	$4034*	$5844*	$8444*

Ports

San Francisco, California
Puerto Vallarta, Mexico
Puerto Quetzal, Guatemala
Puntarenas, Costa Rica
PANAMA CITY (FUERTE AMADOR), PANAMA
Panama Canal Transit
Cartagena, Colombia
Ft. Lauderdale (Port Everglades), Florida

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Ports

San Francisco, California - Puerto Vallarta, Mexico - Puerto Quetzal, Guatemala - Puntarenas, Costa Rica - PANAMA CITY (FUERTE AMADOR), PANAMA - Panama Canal Transit - Cartagena, Colombia - Ft. Lauderdale (Port Everglades), Florida - View more ports

16 Night Panama Canal - Ocean To Ocean (San Francisco To Ft. Lauderdale)

Island Princess M

4.0

(909 Reviews)

2025 sail dates: Dec 07

$1597*

$100/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1597*	$1697*	$2097*	$5899*
See Offers	$1598*	$1698*	$2071*	$2757*
	$1598*	$1698*	$2071*	$2757*
See Offers	$1598*	$1698*	$2070*	$2756*
See Offers	$1598*	$1698*	$2070*	$2756*
	$1598*	$1698*	$2070*	$2756*
See Offers	$1598*	$1698*	$2070*	$2756*
See Offers	$1598*	$1698*	$2071*	$2757*

Ports

Ft. Lauderdale (Port Everglades), Florida
Oranjestad, Aruba
Panama Canal Transit
PANAMA CITY (FUERTE AMADOR), PANAMA
Puntarenas, Costa Rica
Puerto Chiapas (Tapachula), Mexico
Huatulco, Mexico
Puerto Vallarta, Mexico
San Pedro (Los Angeles), California

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Ports

Ft. Lauderdale (Port Everglades), Florida - Oranjestad, Aruba - Panama Canal Transit - PANAMA CITY (FUERTE AMADOR), PANAMA - Puntarenas, Costa Rica - Puerto Chiapas (Tapachula), Mexico - Huatulco, Mexico - Puerto Vallarta, Mexico - San Pedro (Los Angeles), California - View more ports

16 Night Panama Canal - Ocean To Ocean Holiday (Ft. Lauderdale To Los Angeles)

Island Princess M

4.0

(909 Reviews)

2026 sail dates: Dec 12

$1497*

$94/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1497*	$1697*	$2797*	$6099*
See Offers	$1498*	$1668*	$2668*	$3218*
	$1498*	$1668*	$2668*	$3218*
See Offers	$1498*	$1668*	$2668*	$3218*
See Offers	$1498*	$1668*	$2668*	$3218*
	$1498*	$1668*	$2668*	$3218*
See Offers	$1498*	$1668*	$2668*	$3218*
See Offers	$1498*	$1668*	$2668*	$3218*

Ports

Miami, Florida
Cartagena, Colombia
Colon, Panama
Panama Canal Transit
Puerto Caldera, Costa Rica
Puerto Quetzal, Guatemala
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Pedro (Los Angeles), California

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Ports

Miami, Florida - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Puerto Caldera, Costa Rica - Puerto Quetzal, Guatemala - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - View more ports

15 Night Panama Canal: Mexico & Colombia (Miami To Los Angeles)

Norwegian Bliss XL

4.1

(1357 Reviews)

2025 sail dates: Feb 22

$1138*

$76/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1138*	$1688*	$2038*	$8588*
See Offers	$1138*	$1688*	$2038*	$2088*
See Offers	$1138*	$1688*	$2038*	$2088*
See Offers	$1138*	$1688*	$2038*	$2088*
	$1138*	$1688*	$2038*	$2088*
See Offers	$1138*	$1688*	$2038*	$2088*
See Offers	$1138*	$1688*	$2038*	$2088*
See Offers	$1138*	$1688*	$2038*	$2088*
See Offers	$1055*	$1523*	$1820*	$1863*
	$1137*	$1687*	$2037*	$2087*
See Offers	$1138*	$1688*	$2038*	$2088*

Ports

Vancouver (Canada Place), British Columbia
Santa Barbara, California
San Diego, California
Puerto Vallarta, Mexico
Huatulco, Mexico
Puerto Chiapas (Tapachula), Mexico
Puerto Quetzal, Guatemala
Acajutla
Puntarenas, Costa Rica
Panama Canal Transit
Oranjestad, Aruba
Ft. Lauderdale (Port Everglades), Florida

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Ports

Vancouver (Canada Place), British Columbia - Santa Barbara, California - San Diego, California - Puerto Vallarta, Mexico - Huatulco, Mexico - Puerto Chiapas (Tapachula), Mexico - Puerto Quetzal, Guatemala - Acajutla - Puntarenas, Costa Rica - Panama Canal Transit - Oranjestad, Aruba - Ft. Lauderdale (Port Everglades), Florida - View more ports

21 Night Panama Canal (Vancouver To Ft. Lauderdale)

Eurodam L

4.1

(1102 Reviews)

2025 sail dates: Oct 05

$2350*

$112/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$2350*	$2500*	$3830*	$6460*
See Offers	$2350*	$2500*	$3830*	$6460*
See Offers	$2350*	$2500*	$3830*	$6460*
	$2350*	$2500*	$3830*	$6460*
See Offers	$2350*	$2500*	$3830*	$6460*
See Offers	$2350*	$2500*	$3830*	$6460*
See Offers	$2350*	$2500*	$3830*	$6460*
	$2350*	$2500*	$3830*	$6460*
See Offers	$2350*	$2500*	$3830*	$6460*

Ports

Galveston, Texas
Cozumel, Mexico
Puerto Limon, Costa Rica
Colon, Panama
Mahogany Bay, Roatan, Bay Islands, Honduras

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Ports

Galveston, Texas - Cozumel, Mexico - Puerto Limon, Costa Rica - Colon, Panama - Mahogany Bay, Roatan, Bay Islands, Honduras - View more ports

10 Night Panama Canal (Galveston Roundtrip)

Carnival Legend L

3.9

(2187 Reviews)

2025 sail dates: Oct 27, Dec 08

2026 sail dates: Mar 16

$1089*

$109/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1143*	$1343*	$1628*	$3739*
	$1143*	$1343*	$1628*	$3739*
See Offers	$1143*	$1343*	$1628*	$3739*
See Offers	$1143*	$1343*	$1628*	$3739*
	$1143*	$1343*	$1628*	$3739*
See Offers	$1089*	$1279*	$1599*	$3719*
	$1089*	$1279*	$1599*	$3719*
See Offers	$1089*	$1279*	$1599*	$3719*
See Offers	$1089*	$1279*	$1599*	$3719*
	$1089*	$1279*	$1599*	$3719*
See Offers	$1299*	$1449*	$1819*	$3079*
	$1299*	$1449*	$1819*	$3079*
See Offers	$1299*	$1449*	$1819*	$3079*
See Offers	$1299*	$1449*	$1819*	$3079*
	$1299*	$1449*	$1819*	$3079*

Panama Canal, Central America cruises 340 Panama Canal, Central America Cruises Found

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