Panama Canal, Central America cruises 384 Panama Canal, Central America Cruises Found
Your search Clear selections
384 cruises found
Sort by
Filter by
Ports
- Miami, Florida
- George Town, Grand Cayman
- Cartagena, Colombia
- Panama Canal (Cruise Into Canal)
- Colon, Panama
- Puerto Limon, Costa Rica
- Harvest Caye, Belize
- Cozumel, Mexico
Ports
Miami, Florida - George Town, Grand Cayman - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - Harvest Caye, Belize - Cozumel, Mexico - View more ports
11 Night Panama Canal: Mexico Costa Rica & Belize (Miami Roundtrip)
2025 sail dates:
Ports
- New York, New York
- Ft. Lauderdale (Port Everglades), Florida
- Philipsburg, St. Maarten
- Castries, St. Lucia
- Bridgetown, Barbados
- Devils Island, French Guiana
- Cruise Amazon River
- CRUISE BARRA NORTE RIVER
- Macapa, Brazil
- Cross The Equator
- Santarem, Brazil
- Boca Da Valeria, Brazil
- Manaus, Brazil
- Parintins, Brazil
- Alter Do Chao, Brazil
- Port of Spain
- Willemstad, Curacao
- Oranjestad, Aruba
Ports
New York, New York - Ft. Lauderdale (Port Everglades), Florida - Philipsburg, St. Maarten - Castries, St. Lucia - Bridgetown, Barbados - Devils Island, French Guiana - Cruise Amazon River - CRUISE BARRA NORTE RIVER - Macapa, Brazil - Cross The Equator - Santarem, Brazil - Boca Da Valeria, Brazil - Manaus, Brazil - Parintins, Brazil - Alter Do Chao, Brazil - Port of Spain - Willemstad, Curacao - Oranjestad, Aruba - View more ports
Ports
- Colon, Panama
- San Blas Islands, Panama
- Panama Canal Transit
- PLAYA MUERTO, DARIEN, PANAMA
- Fuerte Amador, Panama
- Puerto Quepos, Costa Rica
- Puntarenas, Costa Rica
Ports
Colon, Panama - San Blas Islands, Panama - Panama Canal Transit - PLAYA MUERTO, DARIEN, PANAMA - Fuerte Amador, Panama - Puerto Quepos, Costa Rica - Puntarenas, Costa Rica - View more ports
Ports
- Ft. Lauderdale (Port Everglades), Florida
- George Town, Grand Cayman
- Costa Maya (Mahahual), Mexico
- Belize City, Belize
- Coxen Hole, Roatan, Bay Islands, Honduras
- Cartagena, Colombia
- Panama Canal Transit
- Fuerte Amador, Panama
- Manta, Ecuador
- Guayaquil, Equador
- Salaverry (Trujillo), Peru
- Callao (Lima), Peru
Ports
Ft. Lauderdale (Port Everglades), Florida - George Town, Grand Cayman - Costa Maya (Mahahual), Mexico - Belize City, Belize - Coxen Hole, Roatan, Bay Islands, Honduras - Cartagena, Colombia - Panama Canal Transit - Fuerte Amador, Panama - Manta, Ecuador - Guayaquil, Equador - Salaverry (Trujillo), Peru - Callao (Lima), Peru - View more ports
Ports
- Miami, Florida
- George Town, Grand Cayman
- Cartagena, Colombia
- Panama Canal Transit
- Puntarenas, Costa Rica
- Puerto Corinto, Nicaragua
- Puerto Quetzal, Guatemala
- Acapulco, Mexico
- Cabo San Lucas, Mexico
- Ensenada, Mexico
- San Pedro (Los Angeles), California
- Puerto Plata, Dominican Republic
- San Juan, Puerto Rico
- Basseterre, St. Kitts
- Pointe-A-Pitre, Guadeloupe
- Castries, St. Lucia
- St. John's, Antigua
- St. George's, Grenada
- Bridgetown, Barbados
- Roseau, Dominica
- Gustavia, St. Barthelemy
- Costa Maya (Mahahual), Mexico
- Harvest Caye, Belize
- Coxen Hole, Roatan, Bay Islands, Honduras
- Cozumel, Mexico
- Oranjestad, Aruba
- Willemstad, Curacao
- Kralendijk, Bonaire
- Great Stirrup Cay (Cruise Line Private Island), Bahamas
Ports
Miami, Florida - George Town, Grand Cayman - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Corinto, Nicaragua - Puerto Quetzal, Guatemala - Acapulco, Mexico - Cabo San Lucas, Mexico - Ensenada, Mexico - San Pedro (Los Angeles), California - Puerto Plata, Dominican Republic - San Juan, Puerto Rico - Basseterre, St. Kitts - Pointe-A-Pitre, Guadeloupe - Castries, St. Lucia - St. John's, Antigua - St. George's, Grenada - Bridgetown, Barbados - Roseau, Dominica - Gustavia, St. Barthelemy - Costa Maya (Mahahual), Mexico - Harvest Caye, Belize - Coxen Hole, Roatan, Bay Islands, Honduras - Cozumel, Mexico - Oranjestad, Aruba - Willemstad, Curacao - Kralendijk, Bonaire - Great Stirrup Cay (Cruise Line Private Island), Bahamas - View more ports
Ports
- Miami, Florida
- George Town, Grand Cayman
- Cartagena, Colombia
- Panama Canal Transit
- Puntarenas, Costa Rica
- Puerto Corinto, Nicaragua
- Puerto Quetzal, Guatemala
- Acapulco, Mexico
- Cabo San Lucas, Mexico
- Ensenada, Mexico
- San Pedro (Los Angeles), California
Ports
Miami, Florida - George Town, Grand Cayman - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Corinto, Nicaragua - Puerto Quetzal, Guatemala - Acapulco, Mexico - Cabo San Lucas, Mexico - Ensenada, Mexico - San Pedro (Los Angeles), California - View more ports
Ports
- San Pedro (Los Angeles), California
- Ensenada, Mexico
- Cabo San Lucas, Mexico
- Acapulco, Mexico
- Puerto Quetzal, Guatemala
- Puerto Corinto, Nicaragua
- Panama City, Panama
- Panama Canal Transit
- Cartagena, Colombia
- George Town, Grand Cayman
- Miami, Florida
Ports
San Pedro (Los Angeles), California - Ensenada, Mexico - Cabo San Lucas, Mexico - Acapulco, Mexico - Puerto Quetzal, Guatemala - Puerto Corinto, Nicaragua - Panama City, Panama - Panama Canal Transit - Cartagena, Colombia - George Town, Grand Cayman - Miami, Florida - View more ports
Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
---|---|---|---|---|---|---|
|
See Offers |
N/A |
N/A |
N/A |
$11899* |
|
|
N/A |
N/A |
N/A |
$11899* |
Ports
- Southampton (London), England
- New York, New York
- Miami, Florida
- Cartagena, Colombia
- Panama Canal Transit
- Puerto Quetzal, Guatemala
- Cabo San Lucas, Mexico
- San Francisco, California
Ports
Southampton (London), England - New York, New York - Miami, Florida - Cartagena, Colombia - Panama Canal Transit - Puerto Quetzal, Guatemala - Cabo San Lucas, Mexico - San Francisco, California - View more ports
Ports
- Ft. Lauderdale (Port Everglades), Florida
- Cartagena, Colombia
- Panama Canal (Cruise Into Canal)
- Colon, Panama
- Oranjestad, Aruba
- Willemstad, Curacao
- Kralendijk, Bonaire
Ports
Ft. Lauderdale (Port Everglades), Florida - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Oranjestad, Aruba - Willemstad, Curacao - Kralendijk, Bonaire - View more ports
Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
---|---|---|---|---|---|---|
|
N/A |
N/A |
N/A |
$8263* |
||
|
See Offers |
N/A |
N/A |
N/A |
$8266* |
|
|
See Offers |
N/A |
N/A |
N/A |
$8266* |
|
|
See Offers |
N/A |
N/A |
N/A |
$8267* |
|
|
See Offers |
N/A |
N/A |
N/A |
$8267* |
|
|
See Offers |
N/A |
N/A |
N/A |
$8267* |
|
|
N/A |
N/A |
N/A |
$8266* |
||
|
See Offers |
N/A |
N/A |
N/A |
$8267* |
|
|
$2141* |
$2799* |
$2758* |
$6876* |
||
|
See Offers |
$2144* |
$2802* |
$2762* |
$6879* |
|
|
See Offers |
$2144* |
$2802* |
$2762* |
$6879* |
|
|
See Offers |
$2043* |
$2701* |
$2660* |
$6778* |
|
|
See Offers |
$2145* |
$2803* |
$2762* |
$6880* |
|
|
See Offers |
$2145* |
$2803* |
$2762* |
$6880* |
|
|
$2144* |
$2802* |
$2762* |
$6879* |
||
|
See Offers |
$2043* |
$2701* |
$2660* |
$6778* |
|
|
$1759* |
N/A |
$2449* |
$6170* |
||
|
See Offers |
$1763* |
N/A |
$2452* |
$6174* |
|
|
See Offers |
$1763* |
N/A |
$2452* |
$6174* |
|
|
See Offers |
$1759* |
$2769* |
$2449* |
$6170* |
|
|
See Offers |
$1763* |
N/A |
$2453* |
$6174* |
|
|
See Offers |
$1763* |
N/A |
$2453* |
$6174* |
|
|
$1763* |
N/A |
$2452* |
$6174* |
||
|
See Offers |
$1759* |
$2769* |
$2449* |
$6170* |
Ports
- New York, New York
- Miami, Florida
- Cartagena, Colombia
- Panama Canal Transit
- Puerto Quetzal, Guatemala
- Cabo San Lucas, Mexico
- San Francisco, California
Ports
New York, New York - Miami, Florida - Cartagena, Colombia - Panama Canal Transit - Puerto Quetzal, Guatemala - Cabo San Lucas, Mexico - San Francisco, California - View more ports
Ports
- Ft. Lauderdale (Port Everglades), Florida
- Cozumel, Mexico
- Panama Canal Transit
- Manta, Ecuador
- Salaverry (Trujillo), Peru
- Callao (Lima), Peru
Ports
Ft. Lauderdale (Port Everglades), Florida - Cozumel, Mexico - Panama Canal Transit - Manta, Ecuador - Salaverry (Trujillo), Peru - Callao (Lima), Peru - View more ports
Top positive review
Top critical review
Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
---|---|---|---|---|---|---|
|
N/A |
N/A |
N/A |
$6000* |
||
|
See Offers |
N/A |
N/A |
N/A |
$15000* |
|
|
See Offers |
N/A |
N/A |
N/A |
$15000* |
|
|
N/A |
N/A |
N/A |
$15000* |
Ports
- San Pedro (Los Angeles), California
- Ensenada, Mexico
- Cabo San Lucas, Mexico
- Acapulco, Mexico
- Puerto Quetzal, Guatemala
- Puerto Corinto, Nicaragua
- Puntarenas, Costa Rica
- Panama Canal Transit
- Cartagena, Colombia
- George Town, Grand Cayman
- Miami, Florida
Ports
San Pedro (Los Angeles), California - Ensenada, Mexico - Cabo San Lucas, Mexico - Acapulco, Mexico - Puerto Quetzal, Guatemala - Puerto Corinto, Nicaragua - Puntarenas, Costa Rica - Panama Canal Transit - Cartagena, Colombia - George Town, Grand Cayman - Miami, Florida - View more ports
All prices are per person based on double occupancy and do not include port/government fees and gratuities.
More popular cruise lines sailing to Panama Canal, Central America
More popular departure ports with sailings to Panama Canal, Central America
- Ft. Lauderdale (Port Everglades), Florida Cruises to Panama Canal, Central America
- Miami, Florida Cruises to Panama Canal, Central America
- Tampa, Florida Cruises to Panama Canal, Central America
- Seattle, Washington Cruises to Panama Canal, Central America
- New York, New York Cruises to Panama Canal, Central America