Panama Canal, Central America cruises 385 Panama Canal, Central America Cruises Found
Your search Clear selections
385 cruises found
Sort by
Filter by
Ports
- New York, New York
- Ft. Lauderdale (Port Everglades), Florida
- Philipsburg, St. Maarten
- Castries, St. Lucia
- Bridgetown, Barbados
- Devils Island, French Guiana
- Cruise Amazon River
- CRUISE BARRA NORTE RIVER
- Macapa, Brazil
- Cross The Equator
- Santarem, Brazil
- Boca Da Valeria, Brazil
- Manaus, Brazil
- Parintins, Brazil
- Alter Do Chao, Brazil
- Port of Spain
- Willemstad, Curacao
- Oranjestad, Aruba
Ports
New York, New York - Ft. Lauderdale (Port Everglades), Florida - Philipsburg, St. Maarten - Castries, St. Lucia - Bridgetown, Barbados - Devils Island, French Guiana - Cruise Amazon River - CRUISE BARRA NORTE RIVER - Macapa, Brazil - Cross The Equator - Santarem, Brazil - Boca Da Valeria, Brazil - Manaus, Brazil - Parintins, Brazil - Alter Do Chao, Brazil - Port of Spain - Willemstad, Curacao - Oranjestad, Aruba - View more ports
Ports
- Miami, Florida
- George Town, Grand Cayman
- Cartagena, Colombia
- Panama Canal (Cruise Into Canal)
- Colon, Panama
- Puerto Limon, Costa Rica
- Harvest Caye, Belize
- Cozumel, Mexico
Ports
Miami, Florida - George Town, Grand Cayman - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - Harvest Caye, Belize - Cozumel, Mexico - View more ports
11 Night Panama Canal: Mexico Costa Rica & Belize (Miami Roundtrip)
2025 sail dates:
Ports
- San Pedro (Los Angeles), California
- Puerto Vallarta, Mexico
- Huatulco, Mexico
- San Juan Del Sur, Nicaragua
- Puntarenas, Costa Rica
- PANAMA CITY (FUERTE AMADOR), PANAMA
- Panama Canal Transit
- Oranjestad, Aruba
- Ft. Lauderdale (Port Everglades), Florida
Ports
San Pedro (Los Angeles), California - Puerto Vallarta, Mexico - Huatulco, Mexico - San Juan Del Sur, Nicaragua - Puntarenas, Costa Rica - PANAMA CITY (FUERTE AMADOR), PANAMA - Panama Canal Transit - Oranjestad, Aruba - Ft. Lauderdale (Port Everglades), Florida - View more ports
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
$1259* |
$1489* |
$2059* |
$5759* |
||
|
|
See Offers |
$1259* |
$1373* |
$2026* |
$2504* |
|
|
|
See Offers |
$1259* |
$1373* |
$2026* |
$2504* |
|
|
|
See Offers |
$1259* |
$1373* |
$2026* |
$2504* |
|
|
|
$1259* |
$1373* |
$2026* |
$2504* |
||
|
|
See Offers |
$1259* |
$1373* |
$2026* |
$2504* |
|
|
|
See Offers |
$1259* |
$1373* |
$2026* |
$2504* |
Ports
- Ft. Lauderdale (Port Everglades), Florida
- Cartagena, Colombia
- Panama Canal Transit
- PANAMA CITY (FUERTE AMADOR), PANAMA
- Puntarenas, Costa Rica
- Puerto Chiapas (Tapachula), Mexico
- Huatulco, Mexico
- Puerto Vallarta, Mexico
- San Pedro (Los Angeles), California
- Honolulu, Oahu
Ports
Ft. Lauderdale (Port Everglades), Florida - Cartagena, Colombia - Panama Canal Transit - PANAMA CITY (FUERTE AMADOR), PANAMA - Puntarenas, Costa Rica - Puerto Chiapas (Tapachula), Mexico - Huatulco, Mexico - Puerto Vallarta, Mexico - San Pedro (Los Angeles), California - Honolulu, Oahu - View more ports
22 Night Panama Canal - Ocean To Ocean (Ft. Lauderdale To Honolulu)
2026 sail dates:
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
$3168* |
$3568* |
$4768* |
N/A |
||
|
|
See Offers |
$3419* |
$3869* |
$5169* |
$7119* |
|
|
|
See Offers |
$3418* |
$3868* |
$5168* |
$7118* |
|
|
|
See Offers |
$3418* |
$3868* |
$5168* |
$7118* |
|
|
|
$3419* |
$3869* |
$5169* |
$7119* |
||
|
|
See Offers |
$3418* |
$3868* |
$5168* |
$7118* |
|
|
|
See Offers |
$3419* |
$3869* |
$5169* |
$7119* |
Ports
- Ft. Lauderdale (Port Everglades), Florida
- Cartagena, Colombia
- Panama Canal Transit
- PANAMA CITY (FUERTE AMADOR), PANAMA
- Puntarenas, Costa Rica
- Puerto Chiapas (Tapachula), Mexico
- Huatulco, Mexico
- Puerto Vallarta, Mexico
- San Pedro (Los Angeles), California
Ports
Ft. Lauderdale (Port Everglades), Florida - Cartagena, Colombia - Panama Canal Transit - PANAMA CITY (FUERTE AMADOR), PANAMA - Puntarenas, Costa Rica - Puerto Chiapas (Tapachula), Mexico - Huatulco, Mexico - Puerto Vallarta, Mexico - San Pedro (Los Angeles), California - View more ports
Ports
- San Diego, California
- Puerto Vallarta, Mexico
- Huatulco, Mexico
- Puerto Chiapas (Tapachula), Mexico
- Puerto Quetzal, Guatemala
- Fuerte Amador, Panama
- Panama Canal Transit
- Cartagena, Colombia
- Half Moon Cay, Bahamas (Private Island)
- Miami, Florida
- Philipsburg, St. Maarten
- St. John's, Antigua
- Fort-De-France, Martinique
- Roseau, Dominica
- Basseterre, St. Kitts
- Charlotte Amalie, St. Thomas
Ports
San Diego, California - Puerto Vallarta, Mexico - Huatulco, Mexico - Puerto Chiapas (Tapachula), Mexico - Puerto Quetzal, Guatemala - Fuerte Amador, Panama - Panama Canal Transit - Cartagena, Colombia - Half Moon Cay, Bahamas (Private Island) - Miami, Florida - Philipsburg, St. Maarten - St. John's, Antigua - Fort-De-France, Martinique - Roseau, Dominica - Basseterre, St. Kitts - Charlotte Amalie, St. Thomas - View more ports
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
$3509* |
$4169* |
$5359* |
$7719* |
||
|
|
See Offers |
$3729* |
$4389* |
$5579* |
$7939* |
|
|
|
See Offers |
$3729* |
$4389* |
$5579* |
$7939* |
|
|
|
See Offers |
$3729* |
$4389* |
$5579* |
$7939* |
|
|
|
$3729* |
$4389* |
$5579* |
$7939* |
||
|
See Offers |
$3729* |
$4389* |
$5579* |
$7939* |
|
|
N/A |
N/A |
N/A |
$7914* |
||
|
|
See Offers |
$3729* |
$4389* |
$5579* |
$7939* |
Ports
- Miami, Florida
- Santa Marta, Colombia
- Cartagena, Colombia
- Panama Canal Transit
- Panama City, Panama
- Manta, Ecuador
- Salaverry (Trujillo), Peru
- Callao (Lima), Peru
Ports
Miami, Florida - Santa Marta, Colombia - Cartagena, Colombia - Panama Canal Transit - Panama City, Panama - Manta, Ecuador - Salaverry (Trujillo), Peru - Callao (Lima), Peru - View more ports
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
See Offers |
$2291* |
$2591* |
$3941* |
$10591* |
|
|
|
See Offers |
$1736* |
$2126* |
$3156* |
$4421* |
|
|
|
See Offers |
$2291* |
$2591* |
$3941* |
$4421* |
|
|
|
See Offers |
$2291* |
$2591* |
$3941* |
$4421* |
|
|
|
$1736* |
$2126* |
$3156* |
$4421* |
||
|
|
See Offers |
$1736* |
$2126* |
$3156* |
$4421* |
|
|
|
See Offers |
$2291* |
$2591* |
$3941* |
$4421* |
|
|
|
See Offers |
$2291* |
$2591* |
$3941* |
$4421* |
|
|
|
$1736* |
$2126* |
$3156* |
$4421* |
Ports
- Ft. Lauderdale (Port Everglades), Florida
- Willemstad, Curacao
- Panama Canal Transit
- Fuerte Amador, Panama
- Puntarenas, Costa Rica
- Puerto Chiapas (Tapachula), Mexico
- Huatulco, Mexico
- Puerto Vallarta, Mexico
- San Pedro (Los Angeles), California
Ports
Ft. Lauderdale (Port Everglades), Florida - Willemstad, Curacao - Panama Canal Transit - Fuerte Amador, Panama - Puntarenas, Costa Rica - Puerto Chiapas (Tapachula), Mexico - Huatulco, Mexico - Puerto Vallarta, Mexico - San Pedro (Los Angeles), California - View more ports
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
$999* |
$1977* |
N/A |
N/A |
||
|
|
See Offers |
$1099* |
$1977* |
N/A |
$2217* |
|
|
|
See Offers |
$999* |
$1307* |
N/A |
$2217* |
|
|
|
See Offers |
$1099* |
$1307* |
N/A |
$2217* |
|
|
|
$1099* |
$1977* |
N/A |
$2217* |
||
|
|
See Offers |
$1099* |
$1307* |
N/A |
$2217* |
|
|
|
See Offers |
$1099* |
$1977* |
N/A |
$2217* |
Ports
- Ft. Lauderdale (Port Everglades), Florida
- Oranjestad, Aruba
- Panama Canal Transit
- Fuerte Amador, Panama
- Puntarenas, Costa Rica
- Puerto Chiapas (Tapachula), Mexico
- Huatulco, Mexico
- Puerto Vallarta, Mexico
- San Pedro (Los Angeles), California
- San Diego, California
- San Francisco, California
- Astoria, Oregon
- Victoria, British Columbia
- Vancouver (Canada Place), British Columbia
Ports
Ft. Lauderdale (Port Everglades), Florida - Oranjestad, Aruba - Panama Canal Transit - Fuerte Amador, Panama - Puntarenas, Costa Rica - Puerto Chiapas (Tapachula), Mexico - Huatulco, Mexico - Puerto Vallarta, Mexico - San Pedro (Los Angeles), California - San Diego, California - San Francisco, California - Astoria, Oregon - Victoria, British Columbia - Vancouver (Canada Place), British Columbia - View more ports
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
$2876* |
$3018* |
$4078* |
$7319* |
||
|
|
See Offers |
$2789* |
$3018* |
$4079* |
$4414* |
|
|
|
See Offers |
$2788* |
$3018* |
$4078* |
$4414* |
|
|
|
See Offers |
$2788* |
$3018* |
$4078* |
$4414* |
|
|
|
$2789* |
$3018* |
$4079* |
$4414* |
||
|
|
See Offers |
$2788* |
$3018* |
$4078* |
$4414* |
|
|
|
See Offers |
$2789* |
$3018* |
$4079* |
$4414* |
Ports
- Ft. Lauderdale (Port Everglades), Florida
- Oranjestad, Aruba
- Panama Canal Transit
- PANAMA CITY (FUERTE AMADOR), PANAMA
- Puntarenas, Costa Rica
- Puerto Chiapas (Tapachula), Mexico
- Huatulco, Mexico
- Ensenada, Mexico
- San Pedro (Los Angeles), California
Ports
Ft. Lauderdale (Port Everglades), Florida - Oranjestad, Aruba - Panama Canal Transit - PANAMA CITY (FUERTE AMADOR), PANAMA - Puntarenas, Costa Rica - Puerto Chiapas (Tapachula), Mexico - Huatulco, Mexico - Ensenada, Mexico - San Pedro (Los Angeles), California - View more ports
Ports
- Miami, Florida
- Puerto Plata, Dominican Republic
- San Juan, Puerto Rico
- Philipsburg, St. Maarten
- Charlotte Amalie, St. Thomas
- Tortola, British Virgin Islands
- Castries, St. Lucia
- Oranjestad, Aruba
- Cartagena, Colombia
- Colon, Panama
- Puerto Limon, Costa Rica
- Panama Canal Transit
- Panama City, Panama
Ports
Miami, Florida - Puerto Plata, Dominican Republic - San Juan, Puerto Rico - Philipsburg, St. Maarten - Charlotte Amalie, St. Thomas - Tortola, British Virgin Islands - Castries, St. Lucia - Oranjestad, Aruba - Cartagena, Colombia - Colon, Panama - Puerto Limon, Costa Rica - Panama Canal Transit - Panama City, Panama - View more ports
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
See Offers |
$1005* |
$1005* |
$1575* |
$5855* |
|
|
|
See Offers |
$1005* |
$1005* |
$1575* |
$1875* |
|
|
|
See Offers |
$1005* |
$1005* |
$1575* |
$1875* |
|
|
|
See Offers |
$1005* |
$1005* |
$1575* |
$1875* |
|
|
|
$1005* |
$1005* |
$1575* |
$1875* |
||
|
|
See Offers |
$1005* |
$1005* |
$1575* |
$1875* |
|
|
|
See Offers |
$1005* |
$1005* |
$1575* |
$1875* |
|
|
|
See Offers |
$1005* |
$1005* |
$1575* |
$1875* |
|
|
|
$1005* |
$1005* |
$1575* |
$1875* |
Ports
- San Francisco, California
- Puerto Vallarta, Mexico
- Puerto Quetzal, Guatemala
- Puntarenas, Costa Rica
- Fuerte Amador, Panama
- Panama Canal Transit
- Cartagena, Colombia
- Ft. Lauderdale (Port Everglades), Florida
Ports
San Francisco, California - Puerto Vallarta, Mexico - Puerto Quetzal, Guatemala - Puntarenas, Costa Rica - Fuerte Amador, Panama - Panama Canal Transit - Cartagena, Colombia - Ft. Lauderdale (Port Everglades), Florida - View more ports
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
$1709* |
$2008* |
$2658* |
N/A |
||
|
|
See Offers |
$1709* |
$1854* |
$2658* |
$3308* |
|
|
|
See Offers |
$1709* |
$1854* |
$2658* |
$3307* |
|
|
|
See Offers |
$1709* |
$1854* |
$2658* |
$3307* |
|
|
|
$1709* |
$1854* |
$2658* |
$3308* |
||
|
|
See Offers |
$1709* |
$1854* |
$2658* |
$3307* |
|
|
|
See Offers |
$1709* |
$1854* |
$2658* |
$3308* |
All prices are per person based on double occupancy and do not include port/government fees and gratuities.
More popular cruise lines sailing to Panama Canal, Central America
More popular departure ports with sailings to Panama Canal, Central America
- Ft. Lauderdale (Port Everglades), Florida Cruises to Panama Canal, Central America
- Miami, Florida Cruises to Panama Canal, Central America
- Tampa, Florida Cruises to Panama Canal, Central America
- Seattle, Washington Cruises to Panama Canal, Central America
- New York, New York Cruises to Panama Canal, Central America