Cruises to Panama Canal, Central America leaving Miami, Florida cruise port 66 Panama Canal, Central America Cruises Found
Your search Clear selections
66 cruises found
Sort by
Filter by
Ports
- Miami, Florida
- George Town, Grand Cayman
- Cartagena, Colombia
- Colon, Panama
- Panama Canal (Cruise Into Canal)
- Puerto Limon, Costa Rica
- Harvest Caye, Belize
- Cozumel, Mexico
Ports
Miami, Florida - George Town, Grand Cayman - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - Harvest Caye, Belize - Cozumel, Mexico - View more ports
11 Night Panama Canal: Mexico Costa Rica & Belize (Miami Roundtrip)
2024 sail dates:
2025 sail dates:
Ports
- Miami, Florida
- Cartagena, Colombia
- Panama City, Panama
- Panama Canal Transit
- Puerto Caldera, Costa Rica
- Puerto Quetzal, Guatemala
- Puerto Vallarta, Mexico
- Cabo San Lucas, Mexico
- San Pedro (Los Angeles), California
Ports
Miami, Florida - Cartagena, Colombia - Panama City, Panama - Panama Canal Transit - Puerto Caldera, Costa Rica - Puerto Quetzal, Guatemala - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - View more ports
Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
---|---|---|---|---|---|---|
|
See Offers |
$1543* |
$1893* |
$2263* |
$5363* |
|
|
See Offers |
$1543* |
$1893* |
$2263* |
$2463* |
|
|
See Offers |
$1543* |
$1893* |
$2263* |
$2463* |
|
|
See Offers |
$1543* |
$1893* |
$2263* |
$2463* |
|
|
See Offers |
$1543* |
$1893* |
$2263* |
$2463* |
|
|
See Offers |
$1543* |
$1893* |
$2263* |
$2463* |
|
|
See Offers |
$1543* |
$1893* |
$2263* |
$2463* |
|
|
$1543* |
$1893* |
$2263* |
$2463* |
||
|
See Offers |
$1543* |
$1893* |
$2263* |
$2463* |
Ports
- Miami, Florida
- Cartagena, Colombia
- Colon, Panama
- Panama Canal Transit
- Puntarenas, Costa Rica
- Puerto Quetzal, Guatemala
- Acapulco, Mexico
- Cabo San Lucas, Mexico
- San Pedro (Los Angeles), California
Ports
Miami, Florida - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Acapulco, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - View more ports
15 Night Panama Canal: Mexico & Costa Rica (Miami To Los Angeles)
2026 sail dates:
Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
---|---|---|---|---|---|---|
|
See Offers |
$1997* |
$2647* |
$3347* |
$9097* |
|
|
See Offers |
$1997* |
$2647* |
$3346* |
$3896* |
|
|
See Offers |
$1997* |
$2647* |
$3347* |
$3897* |
|
|
See Offers |
$1997* |
$2647* |
$3347* |
$3897* |
|
|
See Offers |
$1997* |
$2647* |
$3346* |
$3896* |
|
|
See Offers |
$1997* |
$2647* |
$3347* |
$3897* |
|
|
See Offers |
$1997* |
$2647* |
$3347* |
$3897* |
|
|
$1997* |
$2647* |
$3346* |
$3896* |
||
|
See Offers |
$1997* |
$2647* |
$3346* |
$3896* |
Ports
- Miami, Florida
- Cartagena, Colombia
- Colon, Panama
- Panama Canal Transit
- Puntarenas, Costa Rica
- Puerto Quetzal, Guatemala
- Acapulco, Mexico
- Cabo San Lucas, Mexico
- San Pedro (Los Angeles), California
Ports
Miami, Florida - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Acapulco, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - View more ports
15 Night Panama Canal: Mexico & Costa Rica (Miami To Los Angeles)
2026 sail dates:
Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
---|---|---|---|---|---|---|
|
See Offers |
$2097* |
$2897* |
$3477* |
$8897* |
|
|
See Offers |
$2056* |
$2897* |
$3396* |
$3897* |
|
|
See Offers |
$2097* |
$2897* |
$3477* |
$3897* |
|
|
See Offers |
$2097* |
$2897* |
$3477* |
$3897* |
|
|
See Offers |
$2056* |
$2897* |
$3396* |
$3897* |
|
|
See Offers |
$2097* |
$2897* |
$3477* |
$3897* |
|
|
See Offers |
$2097* |
$2897* |
$3477* |
$3897* |
|
|
$2056* |
$2897* |
$3396* |
$3897* |
||
|
See Offers |
$2056* |
$2897* |
$3396* |
$3897* |
Ports
- Miami, Florida
- Falmouth, Jamaica
- Cartagena, Colombia
- Cruise Gatun Lake (Inside Panama Canal)
- Colon, Panama
- Puerto Limon, Costa Rica
- Harvest Caye, Belize
- Cozumel, Mexico
Ports
Miami, Florida - Falmouth, Jamaica - Cartagena, Colombia - Cruise Gatun Lake (Inside Panama Canal) - Colon, Panama - Puerto Limon, Costa Rica - Harvest Caye, Belize - Cozumel, Mexico - View more ports
Ports
- Miami, Florida
- Cartagena, Colombia
- Colon, Panama
- Panama Canal Transit
- Puerto Caldera, Costa Rica
- Puerto Quetzal, Guatemala
- Acapulco, Mexico
- Puerto Vallarta, Mexico
- Cabo San Lucas, Mexico
- San Pedro (Los Angeles), California
Ports
Miami, Florida - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Puerto Caldera, Costa Rica - Puerto Quetzal, Guatemala - Acapulco, Mexico - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - View more ports
Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
---|---|---|---|---|---|---|
|
See Offers |
$1332* |
$1782* |
$2112* |
$4832* |
|
|
See Offers |
$1332* |
$1782* |
$2112* |
$2362* |
|
|
See Offers |
$1332* |
$1782* |
$2112* |
$2362* |
|
|
See Offers |
$1332* |
$1782* |
$2112* |
$2362* |
|
|
See Offers |
$1332* |
$1782* |
$2112* |
$2362* |
|
|
See Offers |
$1228* |
$1610* |
$1891* |
$2103* |
|
|
See Offers |
$1332* |
$1782* |
$2112* |
$2362* |
|
|
$1332* |
$1782* |
$2112* |
$2362* |
||
|
See Offers |
$1332* |
$1782* |
$2112* |
$2362* |
Ports
- Miami, Florida
- George Town, Grand Cayman
- Cartagena, Colombia
- Colon, Panama
- Cruise Gatun Lake And Panama Canal
- Puerto Limon, Costa Rica
- Harvest Caye, Belize
- Cozumel, Mexico
Ports
Miami, Florida - George Town, Grand Cayman - Cartagena, Colombia - Colon, Panama - Cruise Gatun Lake And Panama Canal - Puerto Limon, Costa Rica - Harvest Caye, Belize - Cozumel, Mexico - View more ports
Ports
- Miami, Florida
- Ocho Rios, Jamaica
- Cartagena, Colombia
- Colon, Panama
- Cruise Gatun Lake And Panama Canal
- Puerto Limon, Costa Rica
- Harvest Caye, Belize
- Cozumel, Mexico
Ports
Miami, Florida - Ocho Rios, Jamaica - Cartagena, Colombia - Colon, Panama - Cruise Gatun Lake And Panama Canal - Puerto Limon, Costa Rica - Harvest Caye, Belize - Cozumel, Mexico - View more ports
11 Night Panama Canal: Mexico Costa Rica & Belize (Miami Roundtrip)
2025 sail dates: Dec 22
2026 sail dates:
Ports
- Miami, Florida
- Cartagena, Colombia
- Panama Canal Transit
- Puntarenas, Costa Rica
- Acajutla
- Puerto Quetzal, Guatemala
- Huatulco, Mexico
- Puerto Vallarta, Mexico
- Cabo San Lucas, Mexico
- San Diego, California
Ports
Miami, Florida - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Acajutla - Puerto Quetzal, Guatemala - Huatulco, Mexico - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Diego, California - View more ports
Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
---|---|---|---|---|---|---|
|
$2304* |
$2604* |
$3304* |
$4804* |
||
|
See Offers |
$2399* |
$2699* |
$3399* |
$4899* |
|
|
See Offers |
$2399* |
$2699* |
$3399* |
$4899* |
|
|
See Offers |
$2399* |
$2699* |
$3399* |
$4899* |
|
|
See Offers |
$2399* |
$2699* |
$3399* |
$4899* |
|
|
$2399* |
$2699* |
$3399* |
$4899* |
||
|
See Offers |
$2399* |
$2699* |
$3399* |
$4899* |
Ports
- Miami, Florida
- Great Stirrup Cay (Cruise Line Private Island), Bahamas
- CABO ROJO, DOMINICAN REPUBLIC
- Oranjestad, Aruba
- Willemstad, Curacao
- Colon, Panama
- Cruise Gatun Lake (Inside Panama Canal)
- Puerto Limon, Costa Rica
- George Town, Grand Cayman
Ports
Miami, Florida - Great Stirrup Cay (Cruise Line Private Island), Bahamas - CABO ROJO, DOMINICAN REPUBLIC - Oranjestad, Aruba - Willemstad, Curacao - Colon, Panama - Cruise Gatun Lake (Inside Panama Canal) - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports
Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
---|---|---|---|---|---|---|
|
See Offers |
$1734* |
$2284* |
$3434* |
$8184* |
|
|
See Offers |
$1734* |
$2284* |
$3434* |
$4534* |
|
|
See Offers |
$1734* |
$2284* |
$3434* |
$4534* |
|
|
See Offers |
$1734* |
$2284* |
$3434* |
$4534* |
|
|
See Offers |
$1734* |
$2284* |
$3434* |
$4534* |
|
|
See Offers |
$1734* |
$2284* |
$3434* |
$4534* |
|
|
See Offers |
$1734* |
$2284* |
$3434* |
$4534* |
|
|
$1734* |
$2284* |
$3434* |
$4534* |
||
|
See Offers |
$1734* |
$2284* |
$3434* |
$4534* |
Ports
- Miami, Florida
- Half Moon Cay, Bahamas (Private Island)
- Grand Turk Island
- Amber Cove (Puerto Plata), Dominican Republic
- Key West, Florida
- Cartagena, Colombia
- Panama Canal Transit
- Puntarenas, Costa Rica
- Acajutla
- Puerto Quetzal, Guatemala
- Huatulco, Mexico
- Puerto Vallarta, Mexico
- Cabo San Lucas, Mexico
- San Diego, California
Ports
Miami, Florida - Half Moon Cay, Bahamas (Private Island) - Grand Turk Island - Amber Cove (Puerto Plata), Dominican Republic - Key West, Florida - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Acajutla - Puerto Quetzal, Guatemala - Huatulco, Mexico - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Diego, California - View more ports
Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
---|---|---|---|---|---|---|
|
$3049* |
$3479* |
$4379* |
$6559* |
||
|
See Offers |
$3239* |
$3669* |
$4569* |
$6749* |
|
|
See Offers |
$3239* |
$3669* |
$4569* |
$6749* |
|
|
See Offers |
$3239* |
$3669* |
$4569* |
$6749* |
|
|
See Offers |
$3239* |
$3669* |
$4569* |
$6749* |
|
|
$3239* |
$3669* |
$4569* |
$6749* |
||
|
See Offers |
$3239* |
$3669* |
$4569* |
$6749* |
All prices are per person based on double occupancy and do not include port/government fees and gratuities.