Panama Canal, Central America Cruises from Ft. Lauderdale (Port Everglades), Florida: Best Cruise Prices

Ports

Ft. Lauderdale (Port Everglades), Florida
Cartagena, Colombia
Panama Canal Transit
Puntarenas, Costa Rica
Acajutla
Puerto Quetzal, Guatemala
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Diego, California

Ports

Ft. Lauderdale (Port Everglades), Florida - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Acajutla - Puerto Quetzal, Guatemala - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Diego, California - View more ports

15 Night Panama Canal (Ft. Lauderdale To San Diego)

Eurodam L

4.1

(1100 Reviews)

2026 sail dates: Apr 05

$2609*

$174/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 1100 Eurodam reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$2609*	$3049*	$3839*	$6139*
See Offers	$3224*	$3664*	$4454*	$6754*
See Offers	$2699*	$3139*	$3929*	$6229*
	N/A	N/A	N/A	$6204*
See Offers	$2699*	$3139*	$3929*	$6229*
	$3224*	$3664*	$4454*	$6754*
See Offers	$2699*	$3139*	$3929*	$6229*
See Offers	$3224*	$3664*	$4454*	$6754*

Ports

Ft. Lauderdale (Port Everglades), Florida
Cartagena, Colombia
Panama Canal Transit
Puntarenas, Costa Rica
Acajutla
Puerto Quetzal, Guatemala
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Diego, California
Catalina Island, California
Vancouver (Canada Place), British Columbia

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Acajutla - Puerto Quetzal, Guatemala - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Diego, California - Catalina Island, California - Vancouver (Canada Place), British Columbia - View more ports

19 Night Panama Canal (Ft. Lauderdale To Vancouver)

Eurodam L

4.1

(1100 Reviews)

2026 sail dates: Apr 05

$2829*

$149/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 1100 Eurodam reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$2829*	$3319*	$4209*	$6659*
See Offers	$2944*	$3434*	$4324*	$6774*
See Offers	$2944*	$3434*	$4324*	$6774*
	N/A	N/A	N/A	$6749*
See Offers	$2944*	$3434*	$4324*	$6774*
	$2944*	$3434*	$4324*	$6774*
See Offers	$2944*	$3434*	$4324*	$6774*
See Offers	$2944*	$3434*	$4324*	$6774*

Ports

Ft. Lauderdale (Port Everglades), Florida
Oranjestad, Aruba
Cartagena, Colombia
Colon, Panama
Panama Canal (Cruise Into Canal)
Puerto Limon, Costa Rica
Princess Cays (Cruise Line Private Island)

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Oranjestad, Aruba - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - Princess Cays (Cruise Line Private Island) - View more ports

12 Night Panama Canal With Costa Rica & Caribbean (Ft. Lauderdale Roundtrip)

Caribbean Princess L

3.9

(1889 Reviews)

2026 sail dates: Oct 30, Nov 23, Dec 05

2027 sail dates: Jan 10, Jan 22

$1099*

$92/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 1889 Caribbean Princess reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1149*	$1399*	$2099*	$4399*
See Offers	$1149*	$1259*	$2099*	$2949*
See Offers	$1149*	$1259*	$2099*	$2949*
	$1149*	$1259*	$2099*	$2949*
See Offers	$1149*	$1259*	$2099*	$2949*
See Offers	$1149*	$1259*	$2099*	$2949*
See Offers	$1149*	$1259*	$2099*	$2949*
	$1199*	$1449*	$2149*	$4499*
See Offers	$1199*	$1319*	$2149*	$2999*
See Offers	$1199*	$1319*	$2149*	$2999*
	$1199*	$1319*	$2149*	$2999*
See Offers	$1199*	$1319*	$2149*	$2999*
See Offers	$1199*	$1319*	$2149*	$2999*
See Offers	$1199*	$1319*	$2149*	$2999*
	$1099*	$1299*	$1949*	$4099*
See Offers	$1099*	$1199*	$1949*	$2749*
See Offers	$1099*	$1199*	$1949*	$2749*
	$1099*	$1199*	$1949*	$2749*
See Offers	$1099*	$1199*	$1949*	$2749*
See Offers	$1099*	$1199*	$1949*	$2749*
See Offers	$1099*	$1199*	$1949*	$2749*
	$1149*	$1399*	$2099*	$4399*
See Offers	$1149*	$1269*	$2099*	$2949*
See Offers	$1149*	$1269*	$2099*	$2949*
	$1149*	$1269*	$2099*	$2949*
See Offers	$1149*	$1269*	$2099*	$2949*
See Offers	$1149*	$1269*	$2099*	$2949*
See Offers	$1149*	$1269*	$2099*	$2949*
	$1149*	$1399*	$2099*	$4399*
See Offers	$2709*	$2919*	$4419*	$5949*
See Offers	$1149*	$1259*	$2099*	$2949*
	$2709*	$2919*	$4419*	$5949*
See Offers	$1149*	$1259*	$2099*	$2949*
See Offers	$2709*	$2919*	$4419*	$5949*
See Offers	$1149*	$1259*	$2099*	$2949*

Ports

Ft. Lauderdale (Port Everglades), Florida
Ocho Rios, Jamaica
Oranjestad, Aruba
Cartagena, Colombia
Panama Canal (Cruise Into Canal)
Colon, Panama
Puerto Limon, Costa Rica
George Town, Grand Cayman

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Ocho Rios, Jamaica - Oranjestad, Aruba - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports

12 Night Panama Canal With Costa Rica & Caribbean (Ft. Lauderdale Roundtrip)

Emerald Princess L

4.0

(1206 Reviews)

2024 sail dates: Dec 06

$999*

$83/night*

Oceanview

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 1206 Emerald Princess reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$999*	$999*	$1288*	$5651*
See Offers	$1347*	$1347*	$1636*	$2307*
See Offers	$999*	$999*	$1259*	$1959*
	$1347*	$1347*	$1636*	$2307*
See Offers	$999*	$999*	$1259*	$1959*
See Offers	$1347*	$1347*	$1636*	$2307*
See Offers	$999*	$999*	$1259*	$1959*

Ports

Ft. Lauderdale (Port Everglades), Florida
Cartagena, Colombia
Panama Canal Transit
Puntarenas, Costa Rica
Puerto Quetzal, Guatemala
Huatulco, Mexico
Puerto Vallarta, Mexico
San Diego, California
Catalina Island, California
San Francisco, California
Vancouver (Canada Place), British Columbia

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Huatulco, Mexico - Puerto Vallarta, Mexico - San Diego, California - Catalina Island, California - San Francisco, California - Vancouver (Canada Place), British Columbia - View more ports

20 Night Panama Canal (Ft. Lauderdale To Vancouver)

Eurodam L

4.1

(1100 Reviews)

2025 sail dates: Apr 12

$1839*

$92/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 1100 Eurodam reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1839*	$2059*	$3554*	N/A
See Offers	$2559*	$2779*	$4274*	N/A
See Offers	$1959*	$2179*	$3674*	$7214*
	N/A	N/A	N/A	$7189*
See Offers	$1959*	$2179*	$3674*	$7214*
	$2559*	$2779*	$4274*	N/A
See Offers	$1959*	$2179*	$3674*	$7214*
See Offers	$2559*	$2779*	$4274*	N/A

Ports

Ft. Lauderdale (Port Everglades), Florida
Grand Turk Island
Oranjestad, Aruba
Cartagena, Colombia
Panama Canal Transit
Puerto Caldera, Costa Rica
Acajutla
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Diego, California

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Grand Turk Island - Oranjestad, Aruba - Cartagena, Colombia - Panama Canal Transit - Puerto Caldera, Costa Rica - Acajutla - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Diego, California - View more ports

17 Night Panama Canal (Ft. Lauderdale To San Diego)

Nieuw Amsterdam L

4.1

(788 Reviews)

2025 sail dates: Apr 13

$1784*

$105/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 788 Nieuw Amsterdam reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1784*	$2034*	$3404*	$6184*
See Offers	$2389*	$2639*	$4009*	$7089*
See Offers	$1894*	$2144*	$3514*	$6294*
	N/A	N/A	N/A	$6269*
See Offers	$1894*	$2144*	$3514*	$6294*
	$2389*	$2639*	$4009*	$7089*
See Offers	$1894*	$2144*	$3514*	$6294*
See Offers	$2389*	$2639*	$4009*	$7089*

Ports

Ft. Lauderdale (Port Everglades), Florida
George Town, Grand Cayman
Cartagena, Colombia
Colon, Panama
Panama Canal Transit
Puntarenas, Costa Rica
Puerto Quetzal, Guatemala
Mazatlan, Mexico
San Pedro (Los Angeles), California

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - George Town, Grand Cayman - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Mazatlan, Mexico - San Pedro (Los Angeles), California - View more ports

16 Night Panama Canal Westward (Ft. Lauderdale To Los Angeles)

Celebrity Summit M

4.1

(2235 Reviews)

2025 sail dates: Apr 17

$1202*

$75/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 2235 Celebrity Summit reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1202*	$1591*	$4004*	$17611*
See Offers	$1287*	$1570*	$4169*	$22812*
See Offers	$1314*	$1566*	$3917*	$17671*
See Offers	$1314*	$1566*	$3917*	$17671*
	$1287*	$1570*	$4169*	$22812*
See Offers	$1340*	$1592*	$4644*	$17697*
See Offers	$1287*	$1570*	$4169*	$22812*
See Offers	$1340*	$1592*	$4142*	$17697*

Ports

Ft. Lauderdale (Port Everglades), Florida
Oranjestad, Aruba
Willemstad, Curacao
Cartagena, Colombia
Panama Canal (Cruise Into Canal)
Colon, Panama
Puerto Limon, Costa Rica
Ocho Rios, Jamaica

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Oranjestad, Aruba - Willemstad, Curacao - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - Ocho Rios, Jamaica - View more ports

12 Night Panama Canal With Costa Rica & Caribbean (Ft. Lauderdale Roundtrip)

Emerald Princess L

4.0

(1206 Reviews)

2024 sail dates: Dec 30

$2539*

$212/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 1206 Emerald Princess reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$2539*	$2781*	N/A	$3568*
See Offers	N/A	N/A	N/A	$3568*
See Offers	$2539*	$2781*	N/A	$3568*

Ports

Ft. Lauderdale (Port Everglades), Florida
Oranjestad, Aruba
Panama Canal Transit
PANAMA CITY (FUERTE AMADOR), PANAMA
Puntarenas, Costa Rica
San Juan Del Sur, Nicaragua
Huatulco, Mexico
Puerto Vallarta, Mexico
San Pedro (Los Angeles), California

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Oranjestad, Aruba - Panama Canal Transit - PANAMA CITY (FUERTE AMADOR), PANAMA - Puntarenas, Costa Rica - San Juan Del Sur, Nicaragua - Huatulco, Mexico - Puerto Vallarta, Mexico - San Pedro (Los Angeles), California - View more ports

16 Night Panama Canal - Ocean To Ocean (Ft. Lauderdale To Los Angeles)

Emerald Princess L

4.0

(1206 Reviews)

2025 sail dates: Nov 02

$1229*

$77/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 1206 Emerald Princess reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1229*	$1479*	$2079*	$6960*
See Offers	$1428*	$1549*	$2278*	$3628*
See Offers	$1229*	$1350*	$2079*	$3429*
	$1428*	$1549*	$2278*	$3628*
See Offers	$1229*	$1350*	$2079*	$3429*
See Offers	$1428*	$1549*	$2278*	$3628*

Ports

Ft. Lauderdale (Port Everglades), Florida
Willemstad, Curacao
Kralendijk, Bonaire
Oranjestad, Aruba
Half Moon Cay, Bahamas (Private Island)
Cartagena, Colombia
Panama Canal (Cruise Into Canal)
Colon, Panama
Puerto Limon, Costa Rica
Falmouth, Jamaica

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Willemstad, Curacao - Kralendijk, Bonaire - Oranjestad, Aruba - Half Moon Cay, Bahamas (Private Island) - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - Falmouth, Jamaica - View more ports

21 Night Southern Caribbean & Panama Canal: Abc Islands (Ft. Lauderdale Roundtrip)

Rotterdam L

4.4

(256 Reviews)

2025 sail dates: Nov 07

$2214*

$105/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 256 Rotterdam reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$2214*	$2934*	$3234*	$4894*
See Offers	$2454*	$3174*	$3474*	$5134*
See Offers	$2454*	$3174*	$3474*	$5134*
	N/A	N/A	N/A	$5109*
See Offers	$2454*	$3174*	$3474*	$5134*
	$2454*	$3174*	$3474*	$5134*
See Offers	$2454*	$3174*	$3474*	$5134*
See Offers	$2454*	$3174*	$3474*	$5134*

Cruises to Panama Canal, Central America leaving Ft. Lauderdale (Port Everglades), Florida cruise port 118 Panama Canal, Central America Cruises Found

Your search Clear selections

118 cruises found

Sort by

Filter by

More popular departure ports with sailing to Panama Canal, Central America

More popular cruise destinations from Ft. Lauderdale (Port Everglades), Florida

More popular cruise lines that sail to Panama Canal, Central America