George Town, Grand Cayman cruises 454 George Town, Grand Cayman cruises

Your search Clear selections

Any Destination
All Sail Months
Any Length
George Town, Grand Cayman
Any Cruise Line
Any Ship

Close

454 cruises found

Sort by

Filter by

More

Ports

  • Tampa, Florida
  • George Town, Grand Cayman
  • Montego Bay, Jamaica
  • Coxen Hole, Roatan, Bay Islands, Honduras
  • Belize City, Belize
  • Costa Maya (Mahahual), Mexico
  • Cozumel, Mexico
View more ports

Ports

Tampa, Florida - George Town, Grand Cayman - Montego Bay, Jamaica - Coxen Hole, Roatan, Bay Islands, Honduras - Belize City, Belize - Costa Maya (Mahahual), Mexico - Cozumel, Mexico - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$5399*

 

N/A

N/A

N/A

$5399*

 

N/A

N/A

N/A

$5399*

See Offers

N/A

N/A

N/A

$5399*

Ports

  • San Francisco, California
  • San Pedro (Los Angeles), California
  • Ensenada, Mexico
  • Cabo San Lucas, Mexico
  • Acapulco, Mexico
  • Puerto Quetzal, Guatemala
  • Puerto Corinto, Nicaragua
  • Puntarenas, Costa Rica
  • Panama Canal Transit
  • Cartagena, Colombia
  • George Town, Grand Cayman
  • Miami, Florida
View more ports

Ports

San Francisco, California - San Pedro (Los Angeles), California - Ensenada, Mexico - Cabo San Lucas, Mexico - Acapulco, Mexico - Puerto Quetzal, Guatemala - Puerto Corinto, Nicaragua - Puntarenas, Costa Rica - Panama Canal Transit - Cartagena, Colombia - George Town, Grand Cayman - Miami, Florida - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$13130*

See Offers

N/A

N/A

N/A

$9730*

 

N/A

N/A

N/A

$13399*

 

N/A

N/A

N/A

$13399*

See Offers

N/A

N/A

N/A

$13130*

Ports

  • Ft. Lauderdale (Port Everglades), Florida
  • George Town, Grand Cayman
  • Costa Maya (Mahahual), Mexico
  • Belize City, Belize
  • Coxen Hole, Roatan, Bay Islands, Honduras
  • Cartagena, Colombia
  • Panama Canal Transit
  • Fuerte Amador, Panama
  • Manta, Ecuador
  • Guayaquil, Equador
  • Salaverry (Trujillo), Peru
  • Callao (Lima), Peru
  • Pisco, Peru
  • Iquique, Chile
  • Antofagasta, Chile
  • Coquimbo (La Serena), Chile
  • Valparaiso (Santiago), Chile
  • Puerto Montt, Chile
  • Castro, Isla Chiloe, Chile
  • Cruise Pio Xi Glacier
  • Punta Arenas, Chile
  • Ushuaia, Tierra Del Fuego, Argentina
  • Port Stanley, Falkland Islands
  • Puerto Madryn, Argentina
  • Montevideo, Uruguay
  • Buenos Aires, Argentina
  • CAMBORIU, BRAZIL
  • Sao Francisco Do Sul, Brazil
  • Santos (Sao Paulo), Brazil
  • Ilhabela, Brazil
  • Angras Dos Reis, Brazil
  • Rio De Janeiro, Brazil
  • St. Helena Island (U.K.), South Atlantic
  • Walvis Bay, Namibia
  • Luderitz, Namibia
  • Cape Town, South Africa
  • Mossel Bay, South Africa
  • Port Elizabeth, South Africa
  • East London, South Africa
  • Durban, South Africa
  • Richards Bay, South Africa
  • Maputo, Mozambique
  • ILHA DE MOCAMBIQUE, (MOZAMBIQUE ISLAND) MOZAMBIQUE
  • Zanzibar, Tanzania
  • Mombasa, Kenya
  • Victoria, Mahe, Seychelles
  • La Digue, Seychelles
  • Praslin, Seychelles
  • Male, Maldives
  • Colombo, Sri Lanka
  • Mormugao (Goa), India
  • Mumbai (Bombay), India
  • Salalah, Oman
  • Jeddah, Saudi Arabia
  • Safaga (Luxor), Egypt
  • Aqaba (Petra), Jordan
  • Suez Canal Transit
  • Piraeus (Athens), Greece
  • Giardini Di Naxos (Taormina), Sicily
  • Sorrento, Italy
  • Civitavecchia (Rome), Italy
  • TUSCANY (LIVORNO), ITALY
  • Barcelona, Spain
View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - George Town, Grand Cayman - Costa Maya (Mahahual), Mexico - Belize City, Belize - Coxen Hole, Roatan, Bay Islands, Honduras - Cartagena, Colombia - Panama Canal Transit - Fuerte Amador, Panama - Manta, Ecuador - Guayaquil, Equador - Salaverry (Trujillo), Peru - Callao (Lima), Peru - Pisco, Peru - Iquique, Chile - Antofagasta, Chile - Coquimbo (La Serena), Chile - Valparaiso (Santiago), Chile - Puerto Montt, Chile - Castro, Isla Chiloe, Chile - Cruise Pio Xi Glacier - Punta Arenas, Chile - Ushuaia, Tierra Del Fuego, Argentina - Port Stanley, Falkland Islands - Puerto Madryn, Argentina - Montevideo, Uruguay - Buenos Aires, Argentina - CAMBORIU, BRAZIL - Sao Francisco Do Sul, Brazil - Santos (Sao Paulo), Brazil - Ilhabela, Brazil - Angras Dos Reis, Brazil - Rio De Janeiro, Brazil - St. Helena Island (U.K.), South Atlantic - Walvis Bay, Namibia - Luderitz, Namibia - Cape Town, South Africa - Mossel Bay, South Africa - Port Elizabeth, South Africa - East London, South Africa - Durban, South Africa - Richards Bay, South Africa - Maputo, Mozambique - ILHA DE MOCAMBIQUE, (MOZAMBIQUE ISLAND) MOZAMBIQUE - Zanzibar, Tanzania - Mombasa, Kenya - Victoria, Mahe, Seychelles - La Digue, Seychelles - Praslin, Seychelles - Male, Maldives - Colombo, Sri Lanka - Mormugao (Goa), India - Mumbai (Bombay), India - Salalah, Oman - Jeddah, Saudi Arabia - Safaga (Luxor), Egypt - Aqaba (Petra), Jordan - Suez Canal Transit - Piraeus (Athens), Greece - Giardini Di Naxos (Taormina), Sicily - Sorrento, Italy - Civitavecchia (Rome), Italy - TUSCANY (LIVORNO), ITALY - Barcelona, Spain - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
See Offers

N/A

$66500*

$69900*

$74500*

Ports

  • Ft. Lauderdale (Port Everglades), Florida
  • Cartagena, Colombia
  • Colon, Panama
  • Panama Canal (Cruise Into Canal)
  • Oranjestad, Aruba
  • Kralendijk, Bonaire
  • George Town, Grand Cayman
View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Oranjestad, Aruba - Kralendijk, Bonaire - George Town, Grand Cayman - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

$1410*

N/A

$2315*

$8657*

See Offers

$1402*

N/A

N/A

$8649*

See Offers

$1403*

N/A

N/A

$8650*

 

$1402*

N/A

N/A

$8649*

See Offers

$1403*

N/A

$2307*

$8649*

See Offers

$1403*

N/A

N/A

$8650*

See Offers

$1403*

N/A

N/A

N/A

See Offers

$1402*

N/A

N/A

$8649*

Ports

  • Miami, Florida
  • Oranjestad, Aruba
  • Kralendijk, Bonaire
  • Cartagena, Colombia
  • Ocho Rios, Jamaica
  • George Town, Grand Cayman
View more ports

Ports

Miami, Florida - Oranjestad, Aruba - Kralendijk, Bonaire - Cartagena, Colombia - Ocho Rios, Jamaica - George Town, Grand Cayman - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Ports

  • Miami, Florida
  • George Town, Grand Cayman
  • Cartagena, Colombia
  • Panama Canal Transit
  • Puntarenas, Costa Rica
  • Puerto Corinto, Nicaragua
  • Puerto Quetzal, Guatemala
  • Acapulco, Mexico
  • Cabo San Lucas, Mexico
  • Ensenada, Mexico
  • San Pedro (Los Angeles), California
View more ports

Ports

Miami, Florida - George Town, Grand Cayman - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Corinto, Nicaragua - Puerto Quetzal, Guatemala - Acapulco, Mexico - Cabo San Lucas, Mexico - Ensenada, Mexico - San Pedro (Los Angeles), California - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$10499*

 

N/A

N/A

N/A

$10499*

Ports

  • Miami, Florida
  • George Town, Grand Cayman
  • Montego Bay, Jamaica
  • Coxen Hole, Roatan, Bay Islands, Honduras
  • Costa Maya (Mahahual), Mexico
  • Cozumel, Mexico
  • San Juan, Puerto Rico
  • St. John's, Antigua
  • Castries, St. Lucia
  • Bridgetown, Barbados
  • Philipsburg, St. Maarten
View more ports

Ports

Miami, Florida - George Town, Grand Cayman - Montego Bay, Jamaica - Coxen Hole, Roatan, Bay Islands, Honduras - Costa Maya (Mahahual), Mexico - Cozumel, Mexico - San Juan, Puerto Rico - St. John's, Antigua - Castries, St. Lucia - Bridgetown, Barbados - Philipsburg, St. Maarten - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Ports

  • Miami, Florida
  • San Juan, Puerto Rico
  • St. John's, Antigua
  • Castries, St. Lucia
  • Bridgetown, Barbados
  • Philipsburg, St. Maarten
  • George Town, Grand Cayman
  • Montego Bay, Jamaica
  • Coxen Hole, Roatan, Bay Islands, Honduras
  • Costa Maya (Mahahual), Mexico
  • Cozumel, Mexico
View more ports

Ports

Miami, Florida - San Juan, Puerto Rico - St. John's, Antigua - Castries, St. Lucia - Bridgetown, Barbados - Philipsburg, St. Maarten - George Town, Grand Cayman - Montego Bay, Jamaica - Coxen Hole, Roatan, Bay Islands, Honduras - Costa Maya (Mahahual), Mexico - Cozumel, Mexico - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Ports

  • Tampa, Florida
  • George Town, Grand Cayman
  • Cartagena, Colombia
  • Colon, Panama
  • Panama Canal (Cruise Into Canal)
  • Puerto Limon, Costa Rica
  • Harvest Caye, Belize
  • Cozumel, Mexico
View more ports

Ports

Tampa, Florida - George Town, Grand Cayman - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - Harvest Caye, Belize - Cozumel, Mexico - View more ports

Ports

  • Ft. Lauderdale (Port Everglades), Florida
  • Half Moon Cay, Bahamas (Private Island)
  • Falmouth, Jamaica
  • George Town, Grand Cayman
  • Belize City, Belize
  • Costa Maya (Mahahual), Mexico
  • Cozumel, Mexico
  • Philipsburg, St. Maarten
  • St. John's, Antigua
  • Fort-De-France, Martinique
  • Roseau, Dominica
  • Basseterre, St. Kitts
  • Charlotte Amalie, St. Thomas
View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Half Moon Cay, Bahamas (Private Island) - Falmouth, Jamaica - George Town, Grand Cayman - Belize City, Belize - Costa Maya (Mahahual), Mexico - Cozumel, Mexico - Philipsburg, St. Maarten - St. John's, Antigua - Fort-De-France, Martinique - Roseau, Dominica - Basseterre, St. Kitts - Charlotte Amalie, St. Thomas - View more ports

All prices are per person based on double occupancy and do not include port/government fees and gratuities.