Panama Canal, Central America Cruises : Best Cruise Prices

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Ports

New York, New York
Ft. Lauderdale (Port Everglades), Florida
Philipsburg, St. Maarten
Castries, St. Lucia
Bridgetown, Barbados
Devils Island, French Guiana
Cruise Amazon River
CRUISE BARRA NORTE RIVER
Macapa, Brazil
Cross The Equator
Santarem, Brazil
Boca Da Valeria, Brazil
Manaus, Brazil
Parintins, Brazil
Alter Do Chao, Brazil
Port of Spain
Willemstad, Curacao
Oranjestad, Aruba

Ports

New York, New York - Ft. Lauderdale (Port Everglades), Florida - Philipsburg, St. Maarten - Castries, St. Lucia - Bridgetown, Barbados - Devils Island, French Guiana - Cruise Amazon River - CRUISE BARRA NORTE RIVER - Macapa, Brazil - Cross The Equator - Santarem, Brazil - Boca Da Valeria, Brazil - Manaus, Brazil - Parintins, Brazil - Alter Do Chao, Brazil - Port of Spain - Willemstad, Curacao - Oranjestad, Aruba - View more ports

30 Night Amazon Explorer (New York To Ft. Lauderdale)

Volendam M

4.0

(293 Reviews)

2025 sail dates: Nov 21

$5584*

$186/night*

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Ports

Ft. Lauderdale (Port Everglades), Florida
Oranjestad, Aruba
Cartagena, Colombia
Panama Canal (Cruise Into Canal)
Colon, Panama
Puerto Limon, Costa Rica
Ocho Rios, Jamaica

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Ports

Ft. Lauderdale (Port Everglades), Florida - Oranjestad, Aruba - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - Ocho Rios, Jamaica - View more ports

12 Night Panama Canal With Costa Rica & Caribbean (Ft. Lauderdale Roundtrip)

Emerald Princess L

4.0

(1196 Reviews)

2025 sail dates: Feb 16

$1248*

$104/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1248*	$1848*	$2948*	N/A
See Offers	$1248*	$1354*	$2948*	$3785*
See Offers	$1248*	$1354*	$2948*	$3785*
See Offers	$1249*	$1355*	$2949*	$3785*
	$1249*	$1355*	$2949*	$3785*
See Offers	$1249*	$1355*	$2949*	$3785*
See Offers	$1248*	$1354*	$2948*	$3785*

Ports

Miami, Florida
Cartagena, Colombia
Panama City, Panama
Panama Canal Transit
Puerto Caldera, Costa Rica
Puerto Quetzal, Guatemala
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Pedro (Los Angeles), California

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Ports

Miami, Florida - Cartagena, Colombia - Panama City, Panama - Panama Canal Transit - Puerto Caldera, Costa Rica - Puerto Quetzal, Guatemala - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - View more ports

15 Night Panama Canal: Mexico & Colombia (Miami To Los Angeles)

Norwegian Joy L

4.2

(917 Reviews)

2024 sail dates: Nov 30

$1146*

$76/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1146*	$1296*	$1646*	$4696*
See Offers	$1146*	$1296*	$1646*	$1696*
See Offers	$1146*	$1296*	$1646*	$1696*
See Offers	$1146*	$1296*	$1646*	$1696*
	$1146*	$1296*	$1646*	$1696*
See Offers	$1146*	$1296*	$1646*	$1696*
See Offers	$1146*	$1296*	$1646*	$1696*
See Offers	$1146*	$1296*	$1646*	$1696*
See Offers	$1146*	$1296*	$1646*	$1696*

Ports

San Antonio, Chile
Coquimbo (La Serena), Chile
General San Martin (Pisco), Peru
Callao (Lima), Peru
Salaverry (Trujillo), Peru
Manta, Ecuador
Fuerte Amador, Panama
Panama Canal Transit
George Town, Grand Cayman
Ft. Lauderdale (Port Everglades), Florida

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Ports

San Antonio, Chile - Coquimbo (La Serena), Chile - General San Martin (Pisco), Peru - Callao (Lima), Peru - Salaverry (Trujillo), Peru - Manta, Ecuador - Fuerte Amador, Panama - Panama Canal Transit - George Town, Grand Cayman - Ft. Lauderdale (Port Everglades), Florida - View more ports

17 Night Inca & Panama Canal Discovery (San Antonio To Ft. Lauderdale)

Oosterdam M

4.1

(887 Reviews)

2025 sail dates: Mar 19

2026 sail dates: Mar 22

$1894*

$111/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1894*	$2094*	$3494*	$4494*
See Offers	$1959*	$2159*	$3559*	$4559*
See Offers	$1959*	$2159*	$3559*	$4559*
See Offers	$1959*	$2159*	$3559*	$4559*
See Offers	$1959*	$2159*	$3559*	$4559*
	$1959*	$2159*	$3559*	$4559*
See Offers	$1959*	$2159*	$3559*	$4559*
	$2729*	$2979*	$3729*	$5329*
See Offers	$2799*	$3049*	$3799*	$5399*
See Offers	$2799*	$3049*	$3919*	$5399*
See Offers	$2799*	$3049*	$3919*	$5399*
See Offers	$2799*	$3049*	$3919*	$5399*
	$2799*	$3049*	$3799*	$5399*
See Offers	$2799*	$3049*	$3799*	$5399*

Ports

Ft. Lauderdale (Port Everglades), Florida
Cartagena, Colombia
Panama Canal Transit
Puntarenas, Costa Rica
Puerto Quetzal, Guatemala
Huatulco, Mexico
Puerto Vallarta, Mexico
San Diego, California
Catalina Island, California
San Francisco, California
Vancouver (Canada Place), British Columbia

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Ports

Ft. Lauderdale (Port Everglades), Florida - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Huatulco, Mexico - Puerto Vallarta, Mexico - San Diego, California - Catalina Island, California - San Francisco, California - Vancouver (Canada Place), British Columbia - View more ports

20 Night Panama Canal (Ft. Lauderdale To Vancouver)

Eurodam L

4.1

(1093 Reviews)

2025 sail dates: Apr 12

$1839*

$92/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1839*	$2059*	$3554*	$7094*
See Offers	$1959*	$2179*	$3674*	$7214*
See Offers	$1959*	$2179*	$3674*	$7214*
See Offers	$1959*	$2179*	$3674*	$7214*
See Offers	$1959*	$2179*	$3674*	$7214*
	$1959*	$2179*	$3674*	$7214*
See Offers	$1959*	$2179*	$3674*	$7214*

Ports

Ft. Lauderdale (Port Everglades), Florida
Grand Turk Island
Oranjestad, Aruba
Cartagena, Colombia
Panama Canal Transit
Puerto Caldera, Costa Rica
Acajutla
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Diego, California

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Ports

Ft. Lauderdale (Port Everglades), Florida - Grand Turk Island - Oranjestad, Aruba - Cartagena, Colombia - Panama Canal Transit - Puerto Caldera, Costa Rica - Acajutla - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Diego, California - View more ports

17 Night Panama Canal (Ft. Lauderdale To San Diego)

Nieuw Amsterdam L

4.1

(784 Reviews)

2025 sail dates: Apr 13

$1784*

$105/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1784*	$2034*	$3404*	$6184*
See Offers	$1894*	$2144*	$3514*	$6294*
See Offers	$1894*	$2144*	$3514*	$6294*
See Offers	$1894*	$2144*	$3514*	$6294*
See Offers	$1894*	$2144*	$3514*	$6294*
	$1894*	$2144*	$3514*	$6294*
See Offers	$1894*	$2144*	$3514*	$6294*

Ports

San Diego, California
Puerto Vallarta, Mexico
Huatulco, Mexico
Puerto Chiapas (Tapachula), Mexico
Puerto Quetzal, Guatemala
Acajutla
Puntarenas, Costa Rica
Panama Canal Transit
Oranjestad, Aruba
Ft. Lauderdale (Port Everglades), Florida

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Ports

San Diego, California - Puerto Vallarta, Mexico - Huatulco, Mexico - Puerto Chiapas (Tapachula), Mexico - Puerto Quetzal, Guatemala - Acajutla - Puntarenas, Costa Rica - Panama Canal Transit - Oranjestad, Aruba - Ft. Lauderdale (Port Everglades), Florida - View more ports

17 Night Panama Canal (San Diego To Ft. Lauderdale)

Eurodam L

4.1

(1093 Reviews)

2025 sail dates: Oct 09

$2584*

$152/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$2584*	$3084*	$4084*	$6584*
See Offers	$2585*	$3035*	$3944*	$6689*
See Offers	$2689*	$3189*	$4189*	$6689*
See Offers	$2689*	$3189*	$4189*	$6689*
See Offers	$2689*	$3189*	$4189*	$6689*
	$2585*	$3035*	$3944*	$6689*
See Offers	$2585*	$3035*	$3944*	$6689*

Ports

Ft. Lauderdale (Port Everglades), Florida
Oranjestad, Aruba
Willemstad, Curacao
Cartagena, Colombia
Panama Canal (Cruise Into Canal)
Colon, Panama
Puerto Limon, Costa Rica
George Town, Grand Cayman

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Ports

Ft. Lauderdale (Port Everglades), Florida - Oranjestad, Aruba - Willemstad, Curacao - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports

12 Night Panama Canal With Costa Rica & Caribbean (Ft. Lauderdale Roundtrip)

Caribbean Princess L

3.9

(1888 Reviews)

2026 sail dates: Jan 04, Jan 16, Mar 17

$1358*

$113/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1358*	$1608*	$2108*	$4659*
See Offers	$1358*	$1397*	$2108*	$2658*
See Offers	$1358*	$1397*	$2108*	$2658*
See Offers	$1358*	$1397*	$2108*	$2658*
	$1358*	$1397*	$2108*	$2658*
See Offers	$1358*	$1397*	$2108*	$2658*
See Offers	$1358*	$1397*	$2108*	$2658*
	$1408*	$1958*	$2338*	$4919*
See Offers	$1408*	$1450*	$2338*	$2858*
See Offers	$1408*	$1450*	$2338*	$2858*
See Offers	$1409*	$1451*	$2339*	$2859*
	$1409*	$1451*	$2339*	$2859*
See Offers	$1409*	$1451*	$2339*	$2859*
See Offers	$1408*	$1450*	$2338*	$2858*
	$1628*	$2058*	$2488*	$5059*
See Offers	$1628*	$1677*	$2488*	$3008*
See Offers	$1628*	$1677*	$2488*	$3008*
See Offers	$1628*	$1677*	$2488*	$3008*
	$1628*	$1677*	$2488*	$3008*
See Offers	$1628*	$1677*	$2488*	$3008*
See Offers	$1628*	$1677*	$2488*	$3008*

Ports

Miami, Florida
Cartagena, Colombia
Colon, Panama
Panama Canal Transit
Puntarenas, Costa Rica
Puerto Quetzal, Guatemala
Acapulco, Mexico
Cabo San Lucas, Mexico
San Pedro (Los Angeles), California

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Ports

Miami, Florida - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Acapulco, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - View more ports

15 Night Panama Canal: Mexico & Costa Rica (Miami To Los Angeles)

Norwegian Bliss XL

4.1

(1328 Reviews)

2026 sail dates: Jan 10

$2007*

$134/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$2007*	$2657*	$3357*	$9107*
See Offers	$2007*	$2657*	$3357*	$3907*
See Offers	$2007*	$2657*	$3357*	$3907*
See Offers	$2007*	$2657*	$3357*	$3907*
	$2007*	$2657*	$3357*	$3907*
See Offers	$2007*	$2657*	$3357*	$3907*
See Offers	$2007*	$2657*	$3357*	$3907*
See Offers	$2007*	$2657*	$3357*	$3907*
See Offers	$2007*	$2657*	$3357*	$3907*

Ports

Baltimore, Maryland
CELEBRATION KEY, BAHAMAS
Ocho Rios, Jamaica
Puerto Limon, Costa Rica
Colon, Panama
Grand Turk Island

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Ports

Baltimore, Maryland - CELEBRATION KEY, BAHAMAS - Ocho Rios, Jamaica - Puerto Limon, Costa Rica - Colon, Panama - Grand Turk Island - View more ports

14 Night Carnival Journeys - Panama Canal (Baltimore Roundtrip)

Carnival Pride L

4.0

(2995 Reviews)

2026 sail dates: Jan 11

$1524*

$109/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1524*	$1679*	$2239*	$4829*
	$1524*	$1679*	$2239*	$4829*
See Offers	$1524*	$1679*	$2239*	$4829*
See Offers	$1524*	$1679*	$2239*	$4829*

Ports

Ft. Lauderdale (Port Everglades), Florida
Cartagena, Colombia
Panama Canal Transit
Puntarenas, Costa Rica
Acajutla
Puerto Quetzal, Guatemala
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Diego, California
Catalina Island, California
Vancouver (Canada Place), British Columbia
Seattle, Washington

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Ports

Ft. Lauderdale (Port Everglades), Florida - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Acajutla - Puerto Quetzal, Guatemala - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Diego, California - Catalina Island, California - Vancouver (Canada Place), British Columbia - Seattle, Washington - View more ports

20 Night Panama Canal (Ft. Lauderdale To Seattle)

Eurodam L

4.1

(1093 Reviews)

2026 sail dates: Apr 05

$3159*

$158/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$3159*	$3659*	$4659*	$6859*
See Offers	$3181*	$3631*	$4540*	$7014*
See Offers	$3314*	$3814*	$4814*	$7014*
See Offers	$3314*	$3814*	$4814*	$7014*
See Offers	$3314*	$3814*	$4814*	$7014*
	$3181*	$3631*	$4540*	$7014*
See Offers	$3181*	$3631*	$4540*	$7014*

Panama Canal, Central America cruises 330 Panama Canal, Central America Cruises Found

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