Panama Canal, Central America cruises 343 Panama Canal, Central America Cruises Found

Your search Clear selections

Panama Canal, Central America
All Sail Months
Any Length
Any Port
Any Cruise Line
Any Ship

Close

343 cruises found

Sort by

Filter by

More
More

Ports

  • Vancouver (Canada Place), British Columbia
  • Santa Barbara, California
  • San Diego, California
  • Puerto Vallarta, Mexico
  • Huatulco, Mexico
  • Puerto Chiapas (Tapachula), Mexico
  • Puerto Quetzal, Guatemala
  • Acajutla
  • Puntarenas, Costa Rica
  • Panama Canal Transit
  • Oranjestad, Aruba
  • Ft. Lauderdale (Port Everglades), Florida
  • Grand Turk Island
  • San Juan, Puerto Rico
  • Charlotte Amalie, St. Thomas
  • Half Moon Cay, Bahamas (Private Island)
View more ports

Ports

Vancouver (Canada Place), British Columbia - Santa Barbara, California - San Diego, California - Puerto Vallarta, Mexico - Huatulco, Mexico - Puerto Chiapas (Tapachula), Mexico - Puerto Quetzal, Guatemala - Acajutla - Puntarenas, Costa Rica - Panama Canal Transit - Oranjestad, Aruba - Ft. Lauderdale (Port Everglades), Florida - Grand Turk Island - San Juan, Puerto Rico - Charlotte Amalie, St. Thomas - Half Moon Cay, Bahamas (Private Island) - View more ports

Ports

  • San Pedro (Los Angeles), California
  • Cabo San Lucas, Mexico
  • Acapulco, Mexico
  • Puerto Quetzal, Guatemala
  • Puerto Caldera, Costa Rica
  • Panama City, Panama
  • Panama Canal Transit
  • Cartagena, Colombia
  • Miami, Florida
View more ports

Ports

San Pedro (Los Angeles), California - Cabo San Lucas, Mexico - Acapulco, Mexico - Puerto Quetzal, Guatemala - Puerto Caldera, Costa Rica - Panama City, Panama - Panama Canal Transit - Cartagena, Colombia - Miami, Florida - View more ports

Ports

  • Ft. Lauderdale (Port Everglades), Florida
  • Cartagena, Colombia
  • Panama Canal Transit
  • Puntarenas, Costa Rica
  • Puerto Quetzal, Guatemala
  • Puerto Vallarta, Mexico
  • San Pedro (Los Angeles), California
View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Puerto Vallarta, Mexico - San Pedro (Los Angeles), California - View more ports

Ports

  • Ft. Lauderdale (Port Everglades), Florida
  • Half Moon Cay, Bahamas (Private Island)
  • Willemstad, Curacao
  • Colon, Panama
  • Panama Canal (Cruise Into Canal)
  • Puerto Limon, Costa Rica
  • Falmouth, Jamaica
  • George Town, Grand Cayman
View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Half Moon Cay, Bahamas (Private Island) - Willemstad, Curacao - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - Falmouth, Jamaica - George Town, Grand Cayman - View more ports

Ports

  • Ft. Lauderdale (Port Everglades), Florida
  • Oranjestad, Aruba
  • Cartagena, Colombia
  • Colon, Panama
  • Panama Canal (Cruise Into Canal)
  • Puerto Limon, Costa Rica
  • George Town, Grand Cayman
View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Oranjestad, Aruba - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports

Ports

  • Ft. Lauderdale (Port Everglades), Florida
  • Oranjestad, Aruba
  • Cartagena, Colombia
  • Colon, Panama
  • Panama Canal (Cruise Into Canal)
  • Puerto Limon, Costa Rica
  • George Town, Grand Cayman
View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Oranjestad, Aruba - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports

Ports

  • Galveston, Texas
  • Cozumel, Mexico
  • Puerto Limon, Costa Rica
  • Colon, Panama
  • George Town, Grand Cayman
View more ports

Ports

Galveston, Texas - Cozumel, Mexico - Puerto Limon, Costa Rica - Colon, Panama - George Town, Grand Cayman - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

$1389*

N/A

N/A

$3679*

 

$1389*

N/A

N/A

$3679*

 

$1389*

N/A

N/A

$3679*

 

$1389*

N/A

N/A

$3679*

See Offers

$1389*

N/A

N/A

$3679*

Ports

  • San Francisco, California
  • San Pedro (Los Angeles), California
  • Cabo San Lucas, Mexico
  • Acapulco, Mexico
  • Puerto Quetzal, Guatemala
  • Puerto Caldera, Costa Rica
  • Panama City, Panama
  • Panama Canal Transit
  • Cartagena, Colombia
  • Miami, Florida
View more ports

Ports

San Francisco, California - San Pedro (Los Angeles), California - Cabo San Lucas, Mexico - Acapulco, Mexico - Puerto Quetzal, Guatemala - Puerto Caldera, Costa Rica - Panama City, Panama - Panama Canal Transit - Cartagena, Colombia - Miami, Florida - View more ports

Ports

  • San Diego, California
  • Puerto Vallarta, Mexico
  • Huatulco, Mexico
  • Puerto Chiapas (Tapachula), Mexico
  • Puerto Quetzal, Guatemala
  • Acajutla
  • Puntarenas, Costa Rica
  • Panama Canal Transit
  • Oranjestad, Aruba
  • Ft. Lauderdale (Port Everglades), Florida
View more ports

Ports

San Diego, California - Puerto Vallarta, Mexico - Huatulco, Mexico - Puerto Chiapas (Tapachula), Mexico - Puerto Quetzal, Guatemala - Acajutla - Puntarenas, Costa Rica - Panama Canal Transit - Oranjestad, Aruba - Ft. Lauderdale (Port Everglades), Florida - View more ports

Ports

  • Tampa, Florida
  • George Town, Grand Cayman
  • Puerto Limon, Costa Rica
  • Colon, Panama
  • Oranjestad, Aruba
  • Willemstad, Curacao
  • Amber Cove (Puerto Plata), Dominican Republic
View more ports

Ports

Tampa, Florida - George Town, Grand Cayman - Puerto Limon, Costa Rica - Colon, Panama - Oranjestad, Aruba - Willemstad, Curacao - Amber Cove (Puerto Plata), Dominican Republic - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

All prices are per person based on double occupancy and do not include port/government fees and gratuities.