Puerto Vallarta, Mexico Cruises: Top Itineraries and Pricing

Ports

San Pedro (Los Angeles), California
Cabo San Lucas, Mexico
Puerto Vallarta, Mexico
Acapulco, Mexico
Puerto Quetzal, Guatemala
Panama City, Panama
Panama Canal Transit
Cartagena, Colombia
George Town, Grand Cayman
Miami, Florida

Ports

San Pedro (Los Angeles), California - Cabo San Lucas, Mexico - Puerto Vallarta, Mexico - Acapulco, Mexico - Puerto Quetzal, Guatemala - Panama City, Panama - Panama Canal Transit - Cartagena, Colombia - George Town, Grand Cayman - Miami, Florida - View more ports

16 Night Panama Canal: Mexico & Colombia (Los Angeles To Miami)

Norwegian Joy L

4.2

(850 Reviews)

2025 sail dates: Jan 05

$1129*

$71/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1129*	$1519*	$2129*	$6349*
See Offers	$1129*	$1519*	$2129*	$2569*
See Offers	$1129*	$1519*	$2129*	$2569*
See Offers	$1129*	$1519*	$2129*	$2569*
See Offers	$1129*	$1519*	$2129*	$2569*
	$1129*	$1519*	$2129*	$2569*
See Offers	$1129*	$1519*	$2129*	$2569*
See Offers	$1129*	$1519*	$2129*	$2569*
See Offers	$1129*	$1519*	$2129*	$2569*
	$1129*	$1519*	$2129*	$2569*
See Offers	$1129*	$1519*	$2129*	$2569*

Ports

San Pedro (Los Angeles), California
Cabo San Lucas, Mexico
Puerto Vallarta, Mexico
Manzanillo, Mexico
Puerto Quetzal, Guatemala
Puntarenas, Costa Rica
Panama City, Panama
Panama Canal Transit
Cartagena, Colombia
Miami, Florida

View more ports

Ports

San Pedro (Los Angeles), California - Cabo San Lucas, Mexico - Puerto Vallarta, Mexico - Manzanillo, Mexico - Puerto Quetzal, Guatemala - Puntarenas, Costa Rica - Panama City, Panama - Panama Canal Transit - Cartagena, Colombia - Miami, Florida - View more ports

15 Night Panama Canal: Mexico & Colombia (Los Angeles To Miami)

Norwegian Bliss XL

4.1

(1282 Reviews)

2024 sail dates: Dec 06

$1049*

$70/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1049*	$1329*	$1949*	$7599*
See Offers	$1049*	$1329*	$1949*	$2129*
See Offers	$1019*	$1329*	$1949*	$1859*
See Offers	$1019*	$1329*	$1949*	$1859*
See Offers	$1019*	$1329*	$1949*	$1859*
	$1049*	$1329*	$1949*	$2129*
See Offers	$1049*	$1329*	$1949*	$2129*
See Offers	$1049*	$1329*	$1949*	$2129*
See Offers	$1049*	$1329*	$1949*	$2129*
	$1019*	$1329*	$1949*	$1859*
See Offers	$944*	$1196*	$1754*	$1916*

Ports

Miami, Florida
Cartagena, Colombia
Panama City, Panama
Panama Canal Transit
Puerto Caldera, Costa Rica
Puerto Quetzal, Guatemala
Manzanillo, Mexico
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Pedro (Los Angeles), California
San Francisco, California
Victoria, British Columbia
Seattle, Washington

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Ports

Miami, Florida - Cartagena, Colombia - Panama City, Panama - Panama Canal Transit - Puerto Caldera, Costa Rica - Puerto Quetzal, Guatemala - Manzanillo, Mexico - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - San Francisco, California - Victoria, British Columbia - Seattle, Washington - View more ports

21 Night Panama Canal: Mexico Columbia & Guatemala (Miami To Seattle)

Norwegian Encore XL

4.3

(642 Reviews)

2025 sail dates: Mar 30

$1499*

$71/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1499*	$2249*	$2849*	$10279*
See Offers	$1499*	$2249*	$2849*	$3249*
See Offers	$1499*	$2249*	$2849*	$3249*
See Offers	$1499*	$2249*	$2849*	$3249*
See Offers	$1499*	$2249*	$2849*	$3249*
	$1498*	$2249*	$2848*	$3248*
See Offers	$1499*	$2249*	$2849*	$3249*
See Offers	$1499*	$2249*	$2849*	$3249*
See Offers	$1499*	$2249*	$2849*	$3249*
	$1499*	$2249*	$2849*	$3249*
See Offers	$1499*	$2249*	$2849*	$3249*

Ports

Miami, Florida
Cartagena, Colombia
Panama City, Panama
Panama Canal Transit
Puntarenas, Costa Rica
Puerto Quetzal, Guatemala
Acapulco, Mexico
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Pedro (Los Angeles), California
San Francisco, California
Victoria, British Columbia
Seattle, Washington

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Ports

Miami, Florida - Cartagena, Colombia - Panama City, Panama - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Acapulco, Mexico - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - San Francisco, California - Victoria, British Columbia - Seattle, Washington - View more ports

22 Night Panama Canal: Mexico & Costa Rica (Miami To Seattle)

Norwegian Encore XL

4.3

(642 Reviews)

2026 sail dates: Apr 11

$2109*

$96/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$2109*	$2989*	$3959*	$11549*
See Offers	$2109*	$2989*	$3959*	$4649*
See Offers	$2109*	$2989*	$3959*	$4649*
See Offers	$2109*	$2989*	$3959*	$4649*
	$2109*	$2988*	$3959*	$4648*
See Offers	$2109*	$2989*	$3959*	$4649*
See Offers	$2109*	$2989*	$3959*	$4649*
See Offers	$2109*	$2989*	$3959*	$4649*
	$2109*	$2989*	$3959*	$4649*
See Offers	$2109*	$2989*	$3959*	$4649*

Ports

Seattle, Washington
San Francisco, California
San Pedro (Los Angeles), California
Cabo San Lucas, Mexico
Puerto Vallarta, Mexico
Manzanillo, Mexico
Acapulco, Mexico
Puerto Quetzal, Guatemala
Puerto Caldera, Costa Rica
Panama City, Panama
Panama Canal Transit
Cartagena, Colombia
George Town, Grand Cayman
Miami, Florida

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Ports

Seattle, Washington - San Francisco, California - San Pedro (Los Angeles), California - Cabo San Lucas, Mexico - Puerto Vallarta, Mexico - Manzanillo, Mexico - Acapulco, Mexico - Puerto Quetzal, Guatemala - Puerto Caldera, Costa Rica - Panama City, Panama - Panama Canal Transit - Cartagena, Colombia - George Town, Grand Cayman - Miami, Florida - View more ports

21 Night Panama Canal: Mexico & Colombia (Seattle To Miami)

Norwegian Encore XL

4.3

(642 Reviews)

2024 sail dates: Oct 13

$1609*

$77/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1609*	$1809*	$2419*	$10199*
See Offers	$1609*	$1809*	$2419*	$2699*
See Offers	$1609*	$1809*	$2419*	$2699*
See Offers	$1609*	$1809*	$2419*	$2699*
See Offers	$1609*	$1809*	$2419*	$2699*
	$1608*	$1808*	$2419*	$2698*
See Offers	$1609*	$1809*	$2419*	$2699*
See Offers	$1609*	$1809*	$2419*	$2699*
See Offers	$1448*	$1628*	$2177*	$2429*
	$1609*	$1809*	$2419*	$2699*
See Offers	$1448*	$1628*	$2177*	$2429*

Ports

Miami, Florida
Cartagena, Colombia
Colon, Panama
Panama Canal Transit
Puerto Caldera, Costa Rica
Puerto Quetzal, Guatemala
Manzanillo, Mexico
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Pedro (Los Angeles), California

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Ports

Miami, Florida - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Puerto Caldera, Costa Rica - Puerto Quetzal, Guatemala - Manzanillo, Mexico - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - View more ports

15 Night Panama Canal: Mexico & Colombia (Miami To Los Angeles)

Norwegian Bliss XL

4.1

(1282 Reviews)

2025 sail dates: Feb 22

$1299*

$87/night*

Inside

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1299*	$1999*	$2699*	$8979*
See Offers	$1299*	$1999*	$2699*	$3199*
See Offers	$1299*	$1999*	$2699*	$3199*
See Offers	$1299*	$1999*	$2699*	$3199*
See Offers	$1299*	$1999*	$2699*	$3199*
	$1298*	$1998*	$2698*	$3199*
See Offers	$1299*	$1999*	$2699*	$3199*
See Offers	$1299*	$1999*	$2699*	$3199*
See Offers	$1299*	$1999*	$2699*	$3199*
	$1299*	$1999*	$2699*	$3199*
See Offers	$1299*	$1999*	$2699*	$3199*

Ports

San Pedro (Los Angeles), California
Cabo San Lucas, Mexico
Puerto Vallarta, Mexico
Manzanillo, Mexico
Puerto Quetzal, Guatemala
Puntarenas, Costa Rica
Panama City, Panama
Panama Canal Transit
Cartagena, Colombia
Miami, Florida

View more ports

Ports

San Pedro (Los Angeles), California - Cabo San Lucas, Mexico - Puerto Vallarta, Mexico - Manzanillo, Mexico - Puerto Quetzal, Guatemala - Puntarenas, Costa Rica - Panama City, Panama - Panama Canal Transit - Cartagena, Colombia - Miami, Florida - View more ports

15 Night Panama Canal: Mexico & Colombia (Los Angeles To Miami)

Norwegian Joy L

4.2

(850 Reviews)

2025 sail dates: Feb 06

$1019*

$68/night*

Inside

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1019*	$1450*	$2039*	$6199*
See Offers	$1019*	$1450*	$2039*	$2379*
See Offers	$1019*	$1450*	$2039*	$2379*
See Offers	$1019*	$1450*	$2039*	$2379*
See Offers	$1019*	$1450*	$2039*	$2379*
	$1019*	$1449*	$2039*	$2379*
See Offers	$1019*	$1450*	$2039*	$2379*
See Offers	$1019*	$1450*	$2039*	$2379*
See Offers	$1019*	$1450*	$2039*	$2379*
	$1019*	$1450*	$2039*	$2379*
See Offers	$1019*	$1450*	$2039*	$2379*

Ports

Ft. Lauderdale (Port Everglades), Florida
Cartagena, Colombia
Panama Canal Transit
Puntarenas, Costa Rica
Puerto Quetzal, Guatemala
Huatulco, Mexico
Puerto Vallarta, Mexico
San Diego, California
Catalina Island, California
San Francisco, California
Vancouver (Canada Place), British Columbia

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Ports

Ft. Lauderdale (Port Everglades), Florida - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Huatulco, Mexico - Puerto Vallarta, Mexico - San Diego, California - Catalina Island, California - San Francisco, California - Vancouver (Canada Place), British Columbia - View more ports

20 Night Panama Canal (Ft. Lauderdale To Vancouver)

Eurodam L

4.1

(1068 Reviews)

2025 sail dates: Apr 12

$1719*

$86/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1719*	$2089*	$3144*	$6494*
	$1719*	$2089*	$3144*	$6494*
See Offers	$1719*	$2089*	$3144*	$6494*
See Offers	$1809*	$2279*	$3144*	$6494*
See Offers	$1809*	$2279*	$3144*	$6494*
See Offers	$1809*	$2279*	$3144*	$6494*
See Offers	$1719*	$2089*	$3144*	$6494*
See Offers	$1719*	$2089*	$3144*	$6494*
	$1809*	$2279*	$3144*	$6494*
See Offers	$1719*	$2089*	$3144*	$6494*

Ports

San Pedro (Los Angeles), California
Puerto Vallarta, Mexico
Huatulco, Mexico
San Juan Del Sur, Nicaragua
Puntarenas, Costa Rica
PANAMA CITY (FUERTE AMADOR), PANAMA
Panama Canal Transit
Oranjestad, Aruba
Ft. Lauderdale (Port Everglades), Florida

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Ports

San Pedro (Los Angeles), California - Puerto Vallarta, Mexico - Huatulco, Mexico - San Juan Del Sur, Nicaragua - Puntarenas, Costa Rica - PANAMA CITY (FUERTE AMADOR), PANAMA - Panama Canal Transit - Oranjestad, Aruba - Ft. Lauderdale (Port Everglades), Florida - View more ports

16 Night Panama Canal - Ocean To Ocean (Los Angeles To Ft. Lauderdale)

Island Princess M

4.0

(893 Reviews)

2026 sail dates: Jan 08, Feb 09

$1397*

$87/night*

Inside

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1397*	$2047*	$2397*	$5898*
	$1398*	$1598*	$2348*	$2773*
See Offers	$1398*	$1598*	$2348*	$2773*
See Offers	$1398*	$1598*	$2348*	$2773*
See Offers	$1398*	$1598*	$2348*	$2773*
See Offers	$1398*	$1598*	$2348*	$2773*
See Offers	$1398*	$1598*	$2348*	$2773*
See Offers	$1398*	$1598*	$2348*	$2773*
	$1398*	$1598*	$2348*	$2773*
See Offers	$1398*	$1598*	$2348*	$2773*
	$1397*	$2047*	$2397*	$5898*
	$1398*	$1598*	$2348*	$2773*
See Offers	$1398*	$1598*	$2348*	$2773*
See Offers	$1398*	$1598*	$2348*	$2773*
See Offers	$1398*	$1598*	$2348*	$2773*
See Offers	$1398*	$1598*	$2348*	$2773*
See Offers	$1398*	$1598*	$2348*	$2773*
See Offers	$1398*	$1598*	$2348*	$2773*
	$1398*	$1598*	$2348*	$2773*
See Offers	$1398*	$1598*	$2348*	$2773*

Ports

Vancouver (Canada Place), British Columbia
Santa Barbara, California
San Diego, California
Puerto Vallarta, Mexico
Huatulco, Mexico
Puerto Chiapas (Tapachula), Mexico
Puerto Quetzal, Guatemala
Puntarenas, Costa Rica
Panama Canal Transit
Oranjestad, Aruba
Ft. Lauderdale (Port Everglades), Florida

View more ports

Ports

Vancouver (Canada Place), British Columbia - Santa Barbara, California - San Diego, California - Puerto Vallarta, Mexico - Huatulco, Mexico - Puerto Chiapas (Tapachula), Mexico - Puerto Quetzal, Guatemala - Puntarenas, Costa Rica - Panama Canal Transit - Oranjestad, Aruba - Ft. Lauderdale (Port Everglades), Florida - View more ports

20 Night Panama Canal - Eastbound (Vancouver To Ft. Lauderdale)

Eurodam L

4.1

(1068 Reviews)

2024 sail dates: Oct 06

$1379*

$69/night*

Inside

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1379*	$1659*	$2694*	$5744*
	$1379*	$1659*	$2694*	$5744*
See Offers	$1379*	$1659*	$2694*	$5744*
See Offers	$1379*	$1659*	$2694*	$5744*
See Offers	$1379*	$1659*	$2694*	$5744*
See Offers	$1379*	$1659*	$2694*	$5744*
See Offers	$1379*	$1659*	$2694*	$5744*
See Offers	$1379*	$1659*	$2694*	$5744*
	$1379*	$1659*	$2694*	$5744*
See Offers	$1379*	$1659*	$2694*	$5744*

Puerto Vallarta, Mexico cruises 91 Puerto Vallarta, Mexico cruises

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