Colon, Panama cruises 235 Colon, Panama cruises

Your search Clear selections

Any Destination
All Sail Months
Any Length
Colon, Panama
Any Cruise Line
Any Ship

Close

235 cruises found

Sort by

Filter by

More

Ports

  • Ft. Lauderdale (Port Everglades), Florida
  • Half Moon Cay, Bahamas (Private Island)
  • Oranjestad, Aruba
  • Cartagena, Colombia
  • Colon, Panama
  • Panama Canal (Cruise Into Canal)
  • Puerto Limon, Costa Rica
  • Falmouth, Jamaica
View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Half Moon Cay, Bahamas (Private Island) - Oranjestad, Aruba - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - Falmouth, Jamaica - View more ports

Ports

  • Miami, Florida
  • George Town, Grand Cayman
  • Falmouth, Jamaica
  • Cartagena, Colombia
  • Colon, Panama
  • Cruise Gatun Lake (Inside Panama Canal)
  • Puerto Limon, Costa Rica
  • Harvest Caye, Belize
  • Cozumel, Mexico
View more ports

Ports

Miami, Florida - George Town, Grand Cayman - Falmouth, Jamaica - Cartagena, Colombia - Colon, Panama - Cruise Gatun Lake (Inside Panama Canal) - Puerto Limon, Costa Rica - Harvest Caye, Belize - Cozumel, Mexico - View more ports

Ports

  • Ft. Lauderdale (Port Everglades), Florida
  • George Town, Grand Cayman
  • Cartagena, Colombia
  • Colon, Panama
  • Panama Canal Transit
  • Puntarenas, Costa Rica
  • Puerto Quetzal, Guatemala
  • Puerto Vallarta, Mexico
  • Mazatlan, Mexico
  • San Pedro (Los Angeles), California
View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - George Town, Grand Cayman - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Puerto Vallarta, Mexico - Mazatlan, Mexico - San Pedro (Los Angeles), California - View more ports

Ports

  • Miami, Florida
  • Cartagena, Colombia
  • Colon, Panama
  • Panama Canal Transit
  • Puntarenas, Costa Rica
  • Puerto Quetzal, Guatemala
  • Acapulco, Mexico
  • Cabo San Lucas, Mexico
  • San Pedro (Los Angeles), California
View more ports

Ports

Miami, Florida - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Acapulco, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - View more ports

Ports

  • Miami, Florida
  • Cartagena, Colombia
  • Colon, Panama
  • Panama Canal Transit
  • Puntarenas, Costa Rica
  • Puerto Quetzal, Guatemala
  • Acapulco, Mexico
  • Cabo San Lucas, Mexico
  • San Pedro (Los Angeles), California
View more ports

Ports

Miami, Florida - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Acapulco, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - View more ports

Ports

  • Colon, Panama
  • Cartagena, Colombia
  • Oranjestad, Aruba
  • Kralendijk, Bonaire
View more ports

Ports

Colon, Panama - Cartagena, Colombia - Oranjestad, Aruba - Kralendijk, Bonaire - View more ports

Ports

  • Miami, Florida
  • Falmouth, Jamaica
  • Cartagena, Colombia
  • Cruise Gatun Lake (Inside Panama Canal)
  • Colon, Panama
  • Puerto Limon, Costa Rica
  • Harvest Caye, Belize
  • Cozumel, Mexico
View more ports

Ports

Miami, Florida - Falmouth, Jamaica - Cartagena, Colombia - Cruise Gatun Lake (Inside Panama Canal) - Colon, Panama - Puerto Limon, Costa Rica - Harvest Caye, Belize - Cozumel, Mexico - View more ports

Ports

  • Ft. Lauderdale (Port Everglades), Florida
  • Oranjestad, Aruba
  • Cartagena, Colombia
  • Panama Canal (Cruise Into Canal)
  • Colon, Panama
  • Puerto Limon, Costa Rica
  • George Town, Grand Cayman
View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Oranjestad, Aruba - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports

Ports

  • Miami, Florida
  • Puerto Plata, Dominican Republic
  • San Juan, Puerto Rico
  • Gustavia, St. Barthelemy
  • Pointe-A-Pitre, Guadeloupe
  • Castries, St. Lucia
  • St. John's, Antigua
  • Costa Maya (Mahahual), Mexico
  • Harvest Caye, Belize
  • Coxen Hole, Roatan, Bay Islands, Honduras
  • Puerto Limon, Costa Rica
  • Colon, Panama
  • Cartagena, Colombia
  • Port Royal
View more ports

Ports

Miami, Florida - Puerto Plata, Dominican Republic - San Juan, Puerto Rico - Gustavia, St. Barthelemy - Pointe-A-Pitre, Guadeloupe - Castries, St. Lucia - St. John's, Antigua - Costa Maya (Mahahual), Mexico - Harvest Caye, Belize - Coxen Hole, Roatan, Bay Islands, Honduras - Puerto Limon, Costa Rica - Colon, Panama - Cartagena, Colombia - Port Royal - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$7999*

$13699*

Ports

  • Ft. Lauderdale (Port Everglades), Florida
  • Kralendijk, Bonaire
  • Willemstad, Curacao
  • Cartagena, Colombia
  • Panama Canal (Cruise Into Canal)
  • Colon, Panama
  • Puerto Limon, Costa Rica
  • George Town, Grand Cayman
View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Kralendijk, Bonaire - Willemstad, Curacao - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports

All prices are per person based on double occupancy and do not include port/government fees and gratuities.