Panama Canal, Central America cruises 330 Panama Canal, Central America Cruises Found
Your search Clear selections
330 cruises found
Sort by
Filter by
Ports
- New York, New York
- Ft. Lauderdale (Port Everglades), Florida
- Philipsburg, St. Maarten
- Castries, St. Lucia
- Bridgetown, Barbados
- Devils Island, French Guiana
- Cruise Amazon River
- CRUISE BARRA NORTE RIVER
- Macapa, Brazil
- Cross The Equator
- Santarem, Brazil
- Boca Da Valeria, Brazil
- Manaus, Brazil
- Parintins, Brazil
- Alter Do Chao, Brazil
- Port of Spain
- Willemstad, Curacao
- Oranjestad, Aruba
Ports
New York, New York - Ft. Lauderdale (Port Everglades), Florida - Philipsburg, St. Maarten - Castries, St. Lucia - Bridgetown, Barbados - Devils Island, French Guiana - Cruise Amazon River - CRUISE BARRA NORTE RIVER - Macapa, Brazil - Cross The Equator - Santarem, Brazil - Boca Da Valeria, Brazil - Manaus, Brazil - Parintins, Brazil - Alter Do Chao, Brazil - Port of Spain - Willemstad, Curacao - Oranjestad, Aruba - View more ports
Ports
- Ft. Lauderdale (Port Everglades), Florida
- Half Moon Cay, Bahamas (Private Island)
- Oranjestad, Aruba
- Cartagena, Colombia
- Colon, Panama
- Panama Canal (Cruise Into Canal)
- Puerto Limon, Costa Rica
- Falmouth, Jamaica
- Willemstad, Curacao
- Kralendijk, Bonaire
Ports
Ft. Lauderdale (Port Everglades), Florida - Half Moon Cay, Bahamas (Private Island) - Oranjestad, Aruba - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - Falmouth, Jamaica - Willemstad, Curacao - Kralendijk, Bonaire - View more ports
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
$3169* |
$4069* |
$4619* |
$6269* |
||
|
See Offers |
$3409* |
$4309* |
$4859* |
$6509* |
|
|
|
See Offers |
$3409* |
$4309* |
$4859* |
$6509* |
|
|
|
$3409* |
$4309* |
$4859* |
$6509* |
||
|
|
See Offers |
$3409* |
$4309* |
$4859* |
$6509* |
|
|
|
See Offers |
$3409* |
$4309* |
$4859* |
$6509* |
|
|
|
See Offers |
$3409* |
$4309* |
$4859* |
$6509* |
Ports
- Ft. Lauderdale (Port Everglades), Florida
- Cozumel, Mexico
- Belize City, Belize
- Coxen Hole, Roatan, Bay Islands, Honduras
- Puerto Limon, Costa Rica
- Colon, Panama
- Panama Canal (Cruise Into Canal)
- Montego Bay, Jamaica
Ports
Ft. Lauderdale (Port Everglades), Florida - Cozumel, Mexico - Belize City, Belize - Coxen Hole, Roatan, Bay Islands, Honduras - Puerto Limon, Costa Rica - Colon, Panama - Panama Canal (Cruise Into Canal) - Montego Bay, Jamaica - View more ports
Ports
- Miami, Florida
- George Town, Grand Cayman
- Ocho Rios, Jamaica
- Kralendijk, Bonaire
- Willemstad, Curacao
- Oranjestad, Aruba
- Cartagena, Colombia
- Puerto Limon, Costa Rica
- Panama Canal Transit
- Panama City, Panama
- Puntarenas, Costa Rica
- Puerto Corinto, Nicaragua
- Puerto Vallarta, Mexico
- Cabo San Lucas, Mexico
- Ensenada, Mexico
- Los Angeles, California
Ports
Miami, Florida - George Town, Grand Cayman - Ocho Rios, Jamaica - Kralendijk, Bonaire - Willemstad, Curacao - Oranjestad, Aruba - Cartagena, Colombia - Puerto Limon, Costa Rica - Panama Canal Transit - Panama City, Panama - Puntarenas, Costa Rica - Puerto Corinto, Nicaragua - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - Ensenada, Mexico - Los Angeles, California - View more ports
22 Night Tropical Escape Across The Canal (Miami To Los Angeles)
2026 sail dates:
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
N/A |
N/A |
N/A |
$14599* |
||
|
|
N/A |
N/A |
N/A |
$14599* |
||
|
|
See Offers |
N/A |
N/A |
N/A |
$14599* |
Ports
- Miami, Florida
- George Town, Grand Cayman
- Ocho Rios, Jamaica
- Kralendijk, Bonaire
- Willemstad, Curacao
- Oranjestad, Aruba
- Cartagena, Colombia
- Puerto Limon, Costa Rica
- Panama Canal Transit
- Panama City, Panama
Ports
Miami, Florida - George Town, Grand Cayman - Ocho Rios, Jamaica - Kralendijk, Bonaire - Willemstad, Curacao - Oranjestad, Aruba - Cartagena, Colombia - Puerto Limon, Costa Rica - Panama Canal Transit - Panama City, Panama - View more ports
12 Night Majestic Beaches & Canal Crossing (Miami To Panama City)
2026 sail dates:
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
N/A |
N/A |
N/A |
$8499* |
||
|
|
N/A |
N/A |
N/A |
$8499* |
||
|
|
See Offers |
N/A |
N/A |
N/A |
$8499* |
Ports
- Galveston, Texas
- Montego Bay, Jamaica
- Oranjestad, Aruba
- Willemstad, Curacao
- Cartagena, Colombia
- Colon, Panama
- Puerto Limon, Costa Rica
- Cozumel, Mexico
Ports
Galveston, Texas - Montego Bay, Jamaica - Oranjestad, Aruba - Willemstad, Curacao - Cartagena, Colombia - Colon, Panama - Puerto Limon, Costa Rica - Cozumel, Mexico - View more ports
Ports
- Ft. Lauderdale (Port Everglades), Florida
- Cozumel, Mexico
- Puerto Limon, Costa Rica
- Colon, Panama
- Panama Canal Transit
- Manta, Ecuador
- Callao (Lima), Peru
Ports
Ft. Lauderdale (Port Everglades), Florida - Cozumel, Mexico - Puerto Limon, Costa Rica - Colon, Panama - Panama Canal Transit - Manta, Ecuador - Callao (Lima), Peru - View more ports
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
N/A |
N/A |
N/A |
$11000* |
||
|
|
N/A |
N/A |
N/A |
$11000* |
||
|
|
See Offers |
N/A |
N/A |
N/A |
$11000* |
Ports
- Miami, Florida
- Progreso (Merida), Mexico
- Puerto Limon, Costa Rica
- Panama Canal Transit
- PANAMA CITY (FUERTE AMADOR), PANAMA
- Manta, Ecuador
- Guayaquil, Equador
- Salaverry (Trujillo), Peru
- Callao (Lima), Peru
Ports
Miami, Florida - Progreso (Merida), Mexico - Puerto Limon, Costa Rica - Panama Canal Transit - PANAMA CITY (FUERTE AMADOR), PANAMA - Manta, Ecuador - Guayaquil, Equador - Salaverry (Trujillo), Peru - Callao (Lima), Peru - View more ports
Ports
- Callao (Lima), Peru
- Salaverry (Trujillo), Peru
- MACHALA, ECUADOR
- Guayaquil, Equador
- Manta, Ecuador
- Panama Canal Transit
- Colon, Panama
Ports
Callao (Lima), Peru - Salaverry (Trujillo), Peru - MACHALA, ECUADOR - Guayaquil, Equador - Manta, Ecuador - Panama Canal Transit - Colon, Panama - View more ports
11 Night Marvels Of Ecuador Peru & The Panama Canal (Lima To Colon)
Star Pride XL
2026 sail dates: Jan 29
Ports
- Ft. Lauderdale (Port Everglades), Florida
- Willemstad, Curacao
- Kralendijk, Bonaire
- Oranjestad, Aruba
- Half Moon Cay, Bahamas (Private Island)
- Panama Canal (Cruise Into Canal)
- Colon, Panama
- Puerto Limon, Costa Rica
- Falmouth, Jamaica
- George Town, Grand Cayman
Ports
Ft. Lauderdale (Port Everglades), Florida - Willemstad, Curacao - Kralendijk, Bonaire - Oranjestad, Aruba - Half Moon Cay, Bahamas (Private Island) - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - Falmouth, Jamaica - George Town, Grand Cayman - View more ports
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
$2779* |
$3679* |
$4129* |
$5779* |
||
|
|
See Offers |
$3039* |
$3939* |
$4389* |
$6039* |
|
|
|
See Offers |
$3039* |
$3939* |
$4389* |
$6039* |
|
|
|
$2986* |
$3724* |
$4129* |
$6039* |
||
|
|
See Offers |
$3039* |
$3939* |
$4389* |
$6039* |
|
|
|
See Offers |
$2986* |
$3724* |
$4129* |
$6039* |
|
|
|
See Offers |
$2986* |
$3724* |
$4129* |
$6039* |
Ports
- Miami, Florida
- Cartagena, Colombia
- Panama Canal Transit
- Puntarenas, Costa Rica
- Puerto Corinto, Nicaragua
- Puerto Quetzal, Guatemala
- Acapulco, Mexico
- Cabo San Lucas, Mexico
- Hilo, Hawaii
- Kahului, Maui
- Honolulu, Oahu
- Nawiliwili, Kauai
- Lahaina, Maui
- Cross International Dateline
- Fanning Island, Kiribati
- Rangiroa, French Polynesia
- Raiatea, French Polynesia
- Bora Bora, French Polynesia
- Papeete, Tahiti
Ports
Miami, Florida - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Corinto, Nicaragua - Puerto Quetzal, Guatemala - Acapulco, Mexico - Cabo San Lucas, Mexico - Hilo, Hawaii - Kahului, Maui - Honolulu, Oahu - Nawiliwili, Kauai - Lahaina, Maui - Cross International Dateline - Fanning Island, Kiribati - Rangiroa, French Polynesia - Raiatea, French Polynesia - Bora Bora, French Polynesia - Papeete, Tahiti - View more ports
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
N/A |
N/A |
N/A |
$25999* |
||
|
|
N/A |
N/A |
N/A |
$25999* |
||
|
|
See Offers |
N/A |
N/A |
N/A |
$25999* |
All prices are per person based on double occupancy and do not include port/government fees and gratuities.
More popular cruise lines sailing to Panama Canal, Central America
More popular departure ports with sailings to Panama Canal, Central America
- Ft. Lauderdale (Port Everglades), Florida Cruises to Panama Canal, Central America
- Miami, Florida Cruises to Panama Canal, Central America
- Tampa, Florida Cruises to Panama Canal, Central America
- Seattle, Washington Cruises to Panama Canal, Central America
- Galveston, Texas Cruises to Panama Canal, Central America