Cruises to Panama Canal, Central America leaving Miami, Florida cruise port 69 Panama Canal, Central America Cruises Found
Your search Clear selections
69 cruises found
Sort by
Filter by
Ports
- Miami, Florida
- George Town, Grand Cayman
- Cartagena, Colombia
- Panama Canal (Cruise Into Canal)
- Colon, Panama
- Puerto Limon, Costa Rica
- Harvest Caye, Belize
- Cozumel, Mexico
Ports
Miami, Florida - George Town, Grand Cayman - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - Harvest Caye, Belize - Cozumel, Mexico - View more ports
11 Night Panama Canal: Mexico Costa Rica & Belize (Miami Roundtrip)
2025 sail dates:
Ports
- Miami, Florida
- Cartagena, Colombia
- Panama Canal Transit
- Puntarenas, Costa Rica
- Acajutla
- Puerto Quetzal, Guatemala
- Huatulco, Mexico
- Puerto Vallarta, Mexico
- Cabo San Lucas, Mexico
- San Diego, California
Ports
Miami, Florida - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Acajutla - Puerto Quetzal, Guatemala - Huatulco, Mexico - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Diego, California - View more ports
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
$2304* |
$2604* |
$3304* |
$4804* |
||
|
|
See Offers |
$2399* |
$2699* |
$3399* |
$4899* |
|
|
See Offers |
$2399* |
$2699* |
$3399* |
$4899* |
|
|
|
See Offers |
$2399* |
$2699* |
$3399* |
$4899* |
|
|
N/A |
N/A |
N/A |
$4874* |
||
|
|
$2399* |
$2699* |
$3399* |
$4899* |
||
|
|
See Offers |
$2399* |
$2699* |
$3399* |
$4899* |
|
|
|
See Offers |
$2399* |
$2699* |
$3399* |
$4899* |
Ports
- Miami, Florida
- Half Moon Cay, Bahamas (Private Island)
- Grand Turk Island
- Amber Cove (Puerto Plata), Dominican Republic
- Key West, Florida
- Cartagena, Colombia
- Panama Canal Transit
- Puntarenas, Costa Rica
- Acajutla
- Puerto Quetzal, Guatemala
- Huatulco, Mexico
- Puerto Vallarta, Mexico
- Cabo San Lucas, Mexico
- San Diego, California
Ports
Miami, Florida - Half Moon Cay, Bahamas (Private Island) - Grand Turk Island - Amber Cove (Puerto Plata), Dominican Republic - Key West, Florida - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Acajutla - Puerto Quetzal, Guatemala - Huatulco, Mexico - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Diego, California - View more ports
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
$3049* |
$3479* |
$4379* |
$6559* |
||
|
|
See Offers |
$3239* |
$3669* |
$4569* |
$6749* |
|
|
|
See Offers |
$3239* |
$3669* |
$4569* |
$6749* |
|
|
|
See Offers |
$3239* |
$3669* |
$4569* |
$6749* |
|
|
|
N/A |
N/A |
N/A |
$6724* |
||
|
|
$3239* |
$3669* |
$4569* |
$6749* |
||
|
|
See Offers |
$3239* |
$3669* |
$4569* |
$6749* |
|
|
|
See Offers |
$3239* |
$3669* |
$4569* |
$6749* |
Ports
- Miami, Florida
- Puerto Plata, Dominican Republic
- Catalina Island (Isla Catalina), Dominican Republic
- Willemstad, Curacao
- Oranjestad, Aruba
- Panama Canal Transit
- PANAMA CITY (FUERTE AMADOR), PANAMA
Ports
Miami, Florida - Puerto Plata, Dominican Republic - Catalina Island (Isla Catalina), Dominican Republic - Willemstad, Curacao - Oranjestad, Aruba - Panama Canal Transit - PANAMA CITY (FUERTE AMADOR), PANAMA - View more ports
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
See Offers |
$698* |
N/A |
$1038* |
$12508* |
|
|
|
See Offers |
$935* |
N/A |
N/A |
$12745* |
|
|
|
See Offers |
$935* |
N/A |
N/A |
$12745* |
|
|
|
See Offers |
$935* |
N/A |
N/A |
$12745* |
|
|
|
See Offers |
$662* |
$788* |
$951* |
$1206* |
|
|
|
See Offers |
$698* |
$788* |
$1038* |
$1338* |
|
|
|
See Offers |
$698* |
$788* |
$1038* |
$1338* |
|
|
|
$935* |
N/A |
N/A |
$12745* |
||
|
|
See Offers |
$698* |
$788* |
$1038* |
$1338* |
Ports
- Miami, Florida
- George Town, Grand Cayman
- Cartagena, Colombia
- Panama Canal (Cruise Into Canal)
- Colon, Panama
- Puerto Limon, Costa Rica
- Harvest Caye, Belize
- Cozumel, Mexico
Ports
Miami, Florida - George Town, Grand Cayman - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - Harvest Caye, Belize - Cozumel, Mexico - View more ports
11 Night Panama Canal: Mexico Costa Rica & Belize (Miami Roundtrip)
2024 sail dates:
2025 sail dates:
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
See Offers |
$1091* |
N/A |
N/A |
$3221* |
|
|
|
See Offers |
$1280* |
N/A |
N/A |
N/A |
|
|
|
See Offers |
$1280* |
N/A |
N/A |
N/A |
|
|
|
See Offers |
$1280* |
N/A |
N/A |
N/A |
|
|
|
See Offers |
$1091* |
N/A |
N/A |
$3221* |
|
|
|
See Offers |
$1091* |
N/A |
N/A |
$3221* |
|
|
|
See Offers |
$1091* |
N/A |
N/A |
$3221* |
|
|
|
$1280* |
N/A |
N/A |
N/A |
||
|
|
See Offers |
$1091* |
N/A |
N/A |
$3221* |
Ports
- Miami, Florida
- Puerto Plata, Dominican Republic
- Oranjestad, Aruba
- Cartagena, Colombia
- Colon, Panama
- Panama Canal Transit
- Panama City, Panama
Ports
Miami, Florida - Puerto Plata, Dominican Republic - Oranjestad, Aruba - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Panama City, Panama - View more ports
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
See Offers |
$1274* |
$1624* |
$2374* |
$2574* |
|
|
|
See Offers |
$1274* |
$1624* |
$2374* |
$2574* |
|
|
|
See Offers |
$1274* |
$1624* |
$2374* |
$2574* |
|
|
|
See Offers |
$1274* |
$1624* |
$2374* |
$2574* |
|
|
|
See Offers |
$1274* |
$1624* |
$2374* |
$2574* |
|
|
|
See Offers |
$1274* |
$1624* |
$2374* |
$2574* |
|
|
|
$1274* |
$1624* |
$2374* |
$2574* |
||
|
|
See Offers |
$1274* |
$1624* |
$2374* |
$2574* |
Ports
- Miami, Florida
- Cartagena, Colombia
- Panama Canal Transit
- Puntarenas, Costa Rica
- Acajutla
- Puerto Quetzal, Guatemala
- Huatulco, Mexico
- Puerto Vallarta, Mexico
- Cabo San Lucas, Mexico
- San Diego, California
- Pichilingue (La Paz), Mexico
- Loreto, Mexico
- Guaymas, Mexico
- Topolobampo, Mexico
- Mazatlan, Mexico
- Ensenada, Mexico
Ports
Miami, Florida - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Acajutla - Puerto Quetzal, Guatemala - Huatulco, Mexico - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Diego, California - Pichilingue (La Paz), Mexico - Loreto, Mexico - Guaymas, Mexico - Topolobampo, Mexico - Mazatlan, Mexico - Ensenada, Mexico - View more ports
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
$3819* |
$4289* |
$5509* |
$8379* |
||
|
|
See Offers |
$3954* |
$4424* |
$5644* |
$8514* |
|
|
|
See Offers |
$3954* |
$4424* |
$5644* |
$8514* |
|
|
|
See Offers |
$3954* |
$4424* |
$5644* |
$8514* |
|
|
|
N/A |
N/A |
N/A |
$8489* |
||
|
|
$3954* |
$4424* |
$5644* |
$8514* |
||
|
|
See Offers |
$3954* |
$4424* |
$5644* |
$8514* |
|
|
|
See Offers |
$3954* |
$4424* |
$5644* |
$8514* |
Ports
- Miami, Florida
- Santa Marta, Colombia
- Cartagena, Colombia
- Panama Canal Transit
- Panama City, Panama
- Manta, Ecuador
- Salaverry (Trujillo), Peru
- Callao (Lima), Peru
Ports
Miami, Florida - Santa Marta, Colombia - Cartagena, Colombia - Panama Canal Transit - Panama City, Panama - Manta, Ecuador - Salaverry (Trujillo), Peru - Callao (Lima), Peru - View more ports
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
See Offers |
$2291* |
$2591* |
$3941* |
$10591* |
|
|
|
See Offers |
$1736* |
$2126* |
$3156* |
$4231* |
|
|
|
See Offers |
$1736* |
$2126* |
$3156* |
$4231* |
|
|
|
See Offers |
$1736* |
$2126* |
$3156* |
$4231* |
|
|
|
See Offers |
$2291* |
$2591* |
$3941* |
$4421* |
|
|
|
See Offers |
$2291* |
$2591* |
$3941* |
$4421* |
|
|
|
See Offers |
$2291* |
$2591* |
$3941* |
$4421* |
|
|
|
$1736* |
$2126* |
$3156* |
$4231* |
||
|
|
See Offers |
$2291* |
$2591* |
$3941* |
$4421* |
Ports
- Miami, Florida
- Puerto Plata, Dominican Republic
- San Juan, Puerto Rico
- Philipsburg, St. Maarten
- Charlotte Amalie, St. Thomas
- Tortola, British Virgin Islands
- Castries, St. Lucia
- Oranjestad, Aruba
- Cartagena, Colombia
- Colon, Panama
- Puerto Limon, Costa Rica
- Panama Canal Transit
- Panama City, Panama
Ports
Miami, Florida - Puerto Plata, Dominican Republic - San Juan, Puerto Rico - Philipsburg, St. Maarten - Charlotte Amalie, St. Thomas - Tortola, British Virgin Islands - Castries, St. Lucia - Oranjestad, Aruba - Cartagena, Colombia - Colon, Panama - Puerto Limon, Costa Rica - Panama Canal Transit - Panama City, Panama - View more ports
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
See Offers |
$1005* |
$1005* |
$1575* |
$5855* |
|
|
|
See Offers |
$1398* |
$1398* |
$1968* |
$2268* |
|
|
|
See Offers |
$1398* |
$1398* |
$1968* |
$2268* |
|
|
|
See Offers |
$1398* |
$1398* |
$1968* |
$2268* |
|
|
|
See Offers |
$1005* |
$1005* |
$1575* |
$1875* |
|
|
|
See Offers |
$1005* |
$1005* |
$1575* |
$1875* |
|
|
|
See Offers |
$1005* |
$1005* |
$1575* |
$1875* |
|
|
|
$1398* |
$1398* |
$1968* |
$2268* |
||
|
|
See Offers |
$1005* |
$1005* |
$1575* |
$1875* |
Ports
- Miami, Florida
- Ocho Rios, Jamaica
- Cartagena, Colombia
- Panama Canal (Cruise Into Canal)
- Puerto Limon, Costa Rica
- Harvest Caye, Belize
- Cozumel, Mexico
Ports
Miami, Florida - Ocho Rios, Jamaica - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - Harvest Caye, Belize - Cozumel, Mexico - View more ports
11 Night Panama Canal: Mexico Jamaica & Costa Rica (Miami Roundtrip)
2026 sail dates:
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
See Offers |
$1806* |
$2126* |
$3256* |
$8086* |
|
|
|
See Offers |
$1769* |
$2109* |
$3189* |
$3376* |
|
|
|
See Offers |
$1769* |
$2109* |
$3189* |
$3376* |
|
|
|
See Offers |
$1769* |
$2109* |
$3189* |
$3376* |
|
|
|
See Offers |
$1806* |
$2126* |
$3256* |
$3376* |
|
|
|
See Offers |
$1806* |
$2126* |
$3256* |
$3376* |
|
|
|
See Offers |
$1806* |
$2126* |
$3256* |
$3376* |
|
|
|
$1769* |
$2109* |
$3189* |
$3376* |
||
|
|
See Offers |
$1806* |
$2126* |
$3256* |
$3376* |
Ports
- Miami, Florida
- Montego Bay, Jamaica
- Cartagena, Colombia
- Colon, Panama
- Panama Canal (Cruise Into Canal)
- Puerto Limon, Costa Rica
- Coxen Hole, Roatan, Bay Islands, Honduras
- Costa Maya (Mahahual), Mexico
Ports
Miami, Florida - Montego Bay, Jamaica - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - Coxen Hole, Roatan, Bay Islands, Honduras - Costa Maya (Mahahual), Mexico - View more ports
11 Night Panama Canal: Mexico Costa Rica & Belize (Miami Roundtrip)
2025 sail dates:
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
See Offers |
$1166* |
$1616* |
$3016* |
$6606* |
|
|
|
See Offers |
$1401* |
$1831* |
$3331* |
$3581* |
|
|
|
See Offers |
$1401* |
$1831* |
$3331* |
$3581* |
|
|
|
See Offers |
$1401* |
$1831* |
$3331* |
$3581* |
|
|
|
See Offers |
$1236* |
$1566* |
$3166* |
$3416* |
|
|
|
See Offers |
$1236* |
$1566* |
$3166* |
$3416* |
|
|
|
See Offers |
$1236* |
$1566* |
$3166* |
$3416* |
|
|
|
$1401* |
$1831* |
$3331* |
$3581* |
||
|
|
See Offers |
$1236* |
$1566* |
$3166* |
$3416* |
All prices are per person based on double occupancy and do not include port/government fees and gratuities.