Panama Canal Transit cruises 367 Panama Canal Transit cruises

Your search Clear selections

Any Destination

All Sail Months

Any Length

Panama Canal Transit

Any Cruise Line

Any Ship

367 cruises found

Filters Save search

Ports

San Pedro (Los Angeles), California
Cabo San Lucas, Mexico
Acapulco, Mexico
Puerto Quetzal, Guatemala
Puerto Caldera, Costa Rica
Panama City, Panama
Panama Canal Transit
Cartagena, Colombia
Miami, Florida

View more ports

Ports

San Pedro (Los Angeles), California - Cabo San Lucas, Mexico - Acapulco, Mexico - Puerto Quetzal, Guatemala - Puerto Caldera, Costa Rica - Panama City, Panama - Panama Canal Transit - Cartagena, Colombia - Miami, Florida - View more ports

15 Night Panama Canal: Mexico & Costa Rica (Los Angeles To Miami)

Norwegian Bliss XL

4.1

(1347 Reviews)

2025 sail dates: Dec 05

2026 sail dates: Feb 01

$1804*

$120/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 1347 Norwegian Bliss reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1804*	$2374*	$2954*	$8674*
See Offers	$1804*	$2374*	$2954*	$3424*
See Offers	$1804*	$2374*	$2954*	$3424*
See Offers	$1804*	$2374*	$2954*	$3424*
	$1804*	$2374*	$2954*	$3424*
	$1804*	$2374*	$2954*	$3424*
See Offers	$1804*	$2374*	$2954*	$3424*
	$1804*	$2374*	$2954*	$3424*
See Offers	$1804*	$2374*	$2954*	$3424*
See Offers	$2024*	$2734*	$3454*	$8724*
	$2024*	$2734*	$3373*	$3923*
See Offers	$2024*	$2734*	$3454*	$3924*
See Offers	$2024*	$2734*	$3454*	$3924*
	$2024*	$2734*	$3373*	$3923*
	$2024*	$2734*	$3373*	$3923*
See Offers	$2024*	$2734*	$3454*	$3924*
	$2024*	$2734*	$3373*	$3923*
See Offers	$2024*	$2734*	$3454*	$3924*

Ports

Buenos Aires, Argentina
Montevideo, Uruguay
Port Stanley, Falkland Islands
Cruise Cape Horn
Cruise Beagle Channel
Cruise Glacier Alley
Ushuaia, Tierra Del Fuego, Argentina
Cruise Strait Of Magellan
Punta Arenas, Chile
Cruise Cockburn Channel
Puerto Montt, Chile
San Antonio, Chile
Coquimbo (La Serena), Chile
General San Martin (Pisco), Peru
Callao (Lima), Peru
Salaverry (Trujillo), Peru
Manta, Ecuador
Fuerte Amador, Panama
Panama Canal Transit
George Town, Grand Cayman
Ft. Lauderdale (Port Everglades), Florida

View more ports

Ports

Buenos Aires, Argentina - Montevideo, Uruguay - Port Stanley, Falkland Islands - Cruise Cape Horn - Cruise Beagle Channel - Cruise Glacier Alley - Ushuaia, Tierra Del Fuego, Argentina - Cruise Strait Of Magellan - Punta Arenas, Chile - Cruise Cockburn Channel - Puerto Montt, Chile - San Antonio, Chile - Coquimbo (La Serena), Chile - General San Martin (Pisco), Peru - Callao (Lima), Peru - Salaverry (Trujillo), Peru - Manta, Ecuador - Fuerte Amador, Panama - Panama Canal Transit - George Town, Grand Cayman - Ft. Lauderdale (Port Everglades), Florida - View more ports

31 Night South America Inca & Panama Canal Discovery (Buenos Aires To Ft. Lauderdale)

Oosterdam M

4.1

(889 Reviews)

2025 sail dates:

2026 sail dates: Mar 08

$4369*

$141/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 889 Oosterdam reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$4369*	$4749*	$7089*	$9069*
	$4544*	$4924*	$7264*	$9244*
See Offers	$4544*	$4924*	$7264*	$9244*
	$4544*	$4924*	$7264*	$9244*
See Offers	$4544*	$4924*	$7264*	$9244*
See Offers	$4544*	$4924*	$7264*	$9244*
See Offers	$4544*	$4924*	$7264*	$9244*
	N/A	N/A	N/A	$9219*

Ports

San Pedro (Los Angeles), California
Cabo San Lucas, Mexico
Puerto Vallarta, Mexico
Manzanillo, Mexico
Acapulco, Mexico
Puerto Quetzal, Guatemala
Puntarenas, Costa Rica
Panama City, Panama
Panama Canal Transit
Cartagena, Colombia
Miami, Florida

View more ports

Ports

San Pedro (Los Angeles), California - Cabo San Lucas, Mexico - Puerto Vallarta, Mexico - Manzanillo, Mexico - Acapulco, Mexico - Puerto Quetzal, Guatemala - Puntarenas, Costa Rica - Panama City, Panama - Panama Canal Transit - Cartagena, Colombia - Miami, Florida - View more ports

16 Night Panama Canal: Mexico & Colombia (Los Angeles To Miami)

Norwegian Encore XL

4.3

(693 Reviews)

2025 sail dates: Oct 23

$2123*

$133/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 693 Norwegian Encore reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$2123*	$2793*	$3433*	$11163*
See Offers	$2123*	$2793*	$3433*	$3983*
See Offers	$2123*	$2793*	$3433*	$3983*
See Offers	$2123*	$2793*	$3433*	$3983*
	$2123*	$2793*	$3433*	$3983*
	$2123*	$2793*	$3433*	$3983*
See Offers	$2123*	$2793*	$3433*	$3983*
	$2123*	$2793*	$3433*	$3983*
See Offers	$2123*	$2793*	$3433*	$3983*

Ports

Miami, Florida
Cartagena, Colombia
Colon, Panama
Panama Canal Transit
Puerto Caldera, Costa Rica
Puerto Quetzal, Guatemala
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Pedro (Los Angeles), California

View more ports

Ports

Miami, Florida - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Puerto Caldera, Costa Rica - Puerto Quetzal, Guatemala - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - View more ports

15 Night Panama Canal: Mexico & Colombia (Miami To Los Angeles)

Norwegian Bliss XL

4.1

(1347 Reviews)

2025 sail dates: Feb 22

$1588*

$106/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 1347 Norwegian Bliss reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1588*	$1788*	$2338*	$9428*
See Offers	$1588*	$1788*	$2338*	$2488*
See Offers	$1588*	$1788*	$2338*	$2488*
See Offers	$1588*	$1788*	$2338*	$2488*
	$1588*	$1788*	$2338*	$2488*
	$1588*	$1788*	$2338*	$2488*
See Offers	$1588*	$1788*	$2338*	$2488*
	$1588*	$1788*	$2338*	$2488*
See Offers	$1588*	$1788*	$2338*	$2488*

Ports

Miami, Florida
Cartagena, Colombia
Panama City, Panama
Panama Canal Transit
Puntarenas, Costa Rica
Puerto Quetzal, Guatemala
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Pedro (Los Angeles), California
San Francisco, California

View more ports

Ports

Miami, Florida - Cartagena, Colombia - Panama City, Panama - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - San Francisco, California - View more ports

17 Night Panama Canal: Mexico & Costa Rica (Miami To San Francisco)

Norwegian Encore XL

4.3

(693 Reviews)

2025 sail dates: Mar 30

$2046*

$120/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 693 Norwegian Encore reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$2046*	$2286*	$2816*	$10016*
See Offers	$2046*	$2286*	$2816*	$2916*
See Offers	$2046*	$2286*	$2816*	$2916*
See Offers	$2046*	$2286*	$2816*	$2916*
	$2046*	$2286*	$2816*	$2916*
	$2046*	$2286*	$2816*	$2916*
See Offers	$2046*	$2286*	$2816*	$2916*
	$2046*	$2286*	$2816*	$2916*
See Offers	$2046*	$2286*	$2816*	$2916*

Ports

Miami, Florida
Cartagena, Colombia
Panama Canal Transit
Panama City, Panama
Puerto Caldera, Costa Rica
Puerto Quetzal, Guatemala
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Pedro (Los Angeles), California

View more ports

Ports

Miami, Florida - Cartagena, Colombia - Panama Canal Transit - Panama City, Panama - Puerto Caldera, Costa Rica - Puerto Quetzal, Guatemala - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - View more ports

15 Night Panama Canal: Mexico Colombia & Costa Rica (Miami To Seattle)

Norwegian Encore XL

4.3

(693 Reviews)

2025 sail dates: Mar 30

$1872*

$125/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 693 Norwegian Encore reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1872*	$2222*	$2752*	$9952*
See Offers	$1872*	$2222*	$2752*	$2852*
See Offers	$1872*	$2222*	$2752*	$2852*
See Offers	$1872*	$2222*	$2752*	$2852*
	$1872*	$2222*	$2752*	$2852*
	$1872*	$2222*	$2752*	$2852*
See Offers	$1872*	$2222*	$2752*	$2852*
	$1872*	$2222*	$2752*	$2852*
See Offers	$1872*	$2222*	$2752*	$2852*

Ports

Miami, Florida
Cartagena, Colombia
Colon, Panama
Panama Canal Transit
Puerto Caldera, Costa Rica
Puerto Quetzal, Guatemala
Acapulco, Mexico
Cabo San Lucas, Mexico
San Pedro (Los Angeles), California

View more ports

Ports

Miami, Florida - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Puerto Caldera, Costa Rica - Puerto Quetzal, Guatemala - Acapulco, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - View more ports

15 Night Panama Canal: Mexico & Costa Rica (Miami To Los Angeles)

Norwegian Encore XL

4.3

(693 Reviews)

2025 sail dates: Nov 29

$1915*

$128/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 693 Norwegian Encore reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1915*	$2505*	$3175*	$9075*
See Offers	$1915*	$2505*	$3175*	$3465*
See Offers	$1915*	$2505*	$3175*	$3465*
See Offers	$1915*	$2505*	$3175*	$3465*
	$1915*	$2505*	$3175*	$3465*
	$1915*	$2505*	$3175*	$3465*
See Offers	$1915*	$2505*	$3175*	$3465*
	$1915*	$2505*	$3175*	$3465*
See Offers	$1915*	$2505*	$3175*	$3465*

Ports

San Pedro (Los Angeles), California
Puerto Vallarta, Mexico
Huatulco, Mexico
Puerto Chiapas (Tapachula), Mexico
Puntarenas, Costa Rica
PANAMA CITY (FUERTE AMADOR), PANAMA
Panama Canal Transit
Oranjestad, Aruba
Ft. Lauderdale (Port Everglades), Florida

View more ports

Ports

San Pedro (Los Angeles), California - Puerto Vallarta, Mexico - Huatulco, Mexico - Puerto Chiapas (Tapachula), Mexico - Puntarenas, Costa Rica - PANAMA CITY (FUERTE AMADOR), PANAMA - Panama Canal Transit - Oranjestad, Aruba - Ft. Lauderdale (Port Everglades), Florida - View more ports

16 Night Panama Canal - Ocean To Ocean (Los Angeles To Ft. Lauderdale)

Island Princess M

4.0

(908 Reviews)

2026 sail dates: Oct 25, Nov 26

2027 sail dates: Mar 02, Apr 03

$1349*

$84/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 908 Island Princess reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1449*	$1749*	$2799*	$5849*
	$1449*	$1599*	$2669*	$3219*
See Offers	$1449*	$1599*	$2669*	$3219*
See Offers	$1449*	$1599*	$2669*	$3219*
See Offers	$1449*	$1599*	$2669*	$3219*
	$1449*	$1599*	$2669*	$3219*
See Offers	$1449*	$1599*	$2669*	$3219*
	$1349*	$1499*	$2399*	$5249*
	$1349*	$1479*	$2299*	$2739*
See Offers	$1349*	$1479*	$2299*	$2739*
See Offers	$1349*	$1479*	$2299*	$2739*
See Offers	$1349*	$1479*	$2299*	$2739*
	$1349*	$1479*	$2299*	$2739*
See Offers	$1349*	$1479*	$2299*	$2739*
	$1399*	$1699*	$2699*	$5699*
See Offers	$1399*	$1549*	$2579*	$3109*
See Offers	$1399*	$1549*	$2579*	$3109*
See Offers	$1399*	$1549*	$2579*	$3109*
	$1399*	$1699*	$2699*	$5699*
See Offers	$1399*	$1549*	$2579*	$3099*
See Offers	$1399*	$1549*	$2579*	$3099*
See Offers	$1399*	$1549*	$2579*	$3099*

Ports

San Pedro (Los Angeles), California
Cabo San Lucas, Mexico
Mazatlan, Mexico
Puerto Vallarta, Mexico
Puerto Quetzal, Guatemala
Puerto Caldera, Costa Rica
Panama Canal Transit
Colon, Panama
Cartagena, Colombia
Miami, Florida

View more ports

Ports

San Pedro (Los Angeles), California - Cabo San Lucas, Mexico - Mazatlan, Mexico - Puerto Vallarta, Mexico - Puerto Quetzal, Guatemala - Puerto Caldera, Costa Rica - Panama Canal Transit - Colon, Panama - Cartagena, Colombia - Miami, Florida - View more ports

16 Night Panama Canal: Mexico & Colombia (Los Angeles To Miami)

Norwegian Joy L

4.2

(944 Reviews)

2025 sail dates: Jan 05

$1204*

$75/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 944 Norwegian Joy reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1204*	$1654*	$1704*	$4954*
See Offers	$1204*	$1654*	$1704*	$1884*
See Offers	$1122*	$1504*	$1547*	$1700*
See Offers	$1122*	$1504*	$1547*	$1700*
	$1204*	$1654*	$1704*	$1884*
	$1204*	$1654*	$1704*	$1884*
See Offers	$1204*	$1654*	$1704*	$1884*
	$1204*	$1654*	$1704*	$1884*
See Offers	$1122*	$1504*	$1547*	$1700*

Ports

Miami, Florida
Cartagena, Colombia
Panama Canal Transit
Panama City, Panama
Puntarenas, Costa Rica
Puerto Quetzal, Guatemala
Acapulco, Mexico
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Pedro (Los Angeles), California
San Francisco, California
Victoria, British Columbia
Seattle, Washington

View more ports

Ports

Miami, Florida - Cartagena, Colombia - Panama Canal Transit - Panama City, Panama - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Acapulco, Mexico - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - San Francisco, California - Victoria, British Columbia - Seattle, Washington - View more ports

22 Night Panama Canal: Mexico & Costa Rica (Miami To Seattle)

Norwegian Encore XL

4.3

(693 Reviews)

2026 sail dates: Apr 11

$2929*

$133/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 693 Norwegian Encore reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$2929*	$3819*	$4789*	$12379*
See Offers	$2873*	$3819*	$4673*	$5473*
See Offers	$2929*	$3819*	$4789*	$5479*
See Offers	$2929*	$3819*	$4789*	$5479*
	$2873*	$3819*	$4673*	$5473*
	$2873*	$3819*	$4673*	$5473*
See Offers	$2929*	$3819*	$4789*	$5479*
	$2873*	$3819*	$4673*	$5473*
See Offers	$2929*	$3819*	$4789*	$5479*

1 - 10 of 367

All prices are per person based on double occupancy and do not include port/government fees and gratuities.

Panama Canal Transit cruises 367 Panama Canal Transit cruises

Your search Clear selections

367 cruises found

Sort by

Filter by