Panama Canal, Central America Cruises : Best Cruise Prices

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Ports

Miami, Florida
Cartagena, Colombia
Panama Canal Transit
Panama City, Panama
Puerto Quetzal, Guatemala
Acapulco, Mexico
Puerto Vallarta, Mexico
Mazatlan, Mexico
Cabo San Lucas, Mexico
San Pedro (Los Angeles), California

Ports

Miami, Florida - Cartagena, Colombia - Panama Canal Transit - Panama City, Panama - Puerto Quetzal, Guatemala - Acapulco, Mexico - Puerto Vallarta, Mexico - Mazatlan, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - View more ports

15 Night Panama Canal: Mexico & Colombia (Miami To Los Angeles)

Norwegian Joy L

4.2

(850 Reviews)

2024 sail dates: Nov 30

$969*

$65/night*

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Ports

Ft. Lauderdale (Port Everglades), Florida
Oranjestad, Aruba
Willemstad, Curacao
Cartagena, Colombia
Colon, Panama
Panama Canal (Cruise Into Canal)
Puerto Limon, Costa Rica
George Town, Grand Cayman

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Ports

Ft. Lauderdale (Port Everglades), Florida - Oranjestad, Aruba - Willemstad, Curacao - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports

12 Night Panama Canal With Costa Rica & Caribbean (Ft. Lauderdale Roundtrip)

Emerald Princess L

4.0

(1165 Reviews)

2024 sail dates: Oct 31, Nov 12, Nov 24

2025 sail dates: Mar 12

$597*

$50/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$727*	$1356*	$1947*	$5714*
	$728*	$933*	$1948*	$2078*
See Offers	$728*	$933*	$1948*	$2900*
See Offers	$728*	$933*	$1948*	$2900*
See Offers	$728*	$933*	$1948*	$2900*
See Offers	$728*	$933*	$1948*	$2078*
See Offers	$728*	$933*	$1948*	$2078*
See Offers	$728*	$933*	$1948*	$2078*
	$728*	$933*	$1948*	$2900*
	$697*	$1033*	$1447*	$4957*
	$698*	$815*	$1448*	$1848*
See Offers	$698*	$815*	$1448*	$1848*
See Offers	$698*	$815*	$1448*	$1848*
See Offers	$698*	$815*	$1448*	$1848*
See Offers	$698*	$815*	$1448*	$1848*
See Offers	$698*	$815*	$1448*	$1848*
See Offers	$698*	$815*	$1448*	$1848*
See Offers	$698*	$815*	$1448*	$1848*
	$698*	$815*	$1448*	$1848*
	$597*	$917*	$1397*	$3598*
	$598*	$688*	$1398*	$1798*
See Offers	$598*	$688*	$1398*	$1798*
See Offers	$598*	$688*	$1398*	$1798*
See Offers	$598*	$688*	$1398*	$1798*
See Offers	$598*	$688*	$1398*	$1798*
See Offers	$598*	$688*	$1398*	$1798*
See Offers	$598*	$688*	$1398*	$1798*
	$598*	$688*	$1398*	$1798*
	$827*	$1297*	$1847*	$4098*
See Offers	$828*	$952*	$1848*	$2248*
	$828*	$952*	$1848*	$2039*
See Offers	$828*	$952*	$1848*	$2248*
See Offers	$828*	$952*	$1848*	$2248*
See Offers	$828*	$952*	$1848*	$2248*
See Offers	$828*	$952*	$1848*	$2039*
See Offers	$828*	$952*	$1848*	$2039*
See Offers	$828*	$952*	$1848*	$2039*
See Offers	$828*	$952*	$1848*	$2039*
	$828*	$952*	$1848*	$2248*

Ports

San Pedro (Los Angeles), California
Cabo San Lucas, Mexico
Acapulco, Mexico
Puerto Quetzal, Guatemala
Puntarenas, Costa Rica
Panama City, Panama
Panama Canal Transit
Cartagena, Colombia
Miami, Florida

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Ports

San Pedro (Los Angeles), California - Cabo San Lucas, Mexico - Acapulco, Mexico - Puerto Quetzal, Guatemala - Puntarenas, Costa Rica - Panama City, Panama - Panama Canal Transit - Cartagena, Colombia - Miami, Florida - View more ports

15 Night Panama Canal: Mexico & Costa Rica (Los Angeles To Miami)

Norwegian Bliss XL

4.1

(1281 Reviews)

2025 sail dates: Dec 05

2026 sail dates: Feb 01

$1399*

$93/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1399*	$2049*	$2749*	$8099*
See Offers	$1399*	$2049*	$2749*	$3299*
See Offers	$1399*	$2049*	$2749*	$3299*
See Offers	$1399*	$2049*	$2749*	$3299*
	$1398*	$2048*	$2748*	$3298*
See Offers	$1399*	$2049*	$2749*	$3299*
See Offers	$1399*	$2049*	$2749*	$3299*
See Offers	$1399*	$2049*	$2749*	$3299*
	$1399*	$2049*	$2749*	$3299*
See Offers	$1399*	$2049*	$2749*	$3299*
See Offers	$1449*	$2159*	$2879*	$8149*
See Offers	$1449*	$2159*	$2809*	$3349*
See Offers	$1449*	$2159*	$2809*	$3349*
See Offers	$1449*	$2159*	$2809*	$3349*
	$1448*	$2159*	$2878*	$3348*
See Offers	$1449*	$2159*	$2879*	$3349*
See Offers	$1449*	$2159*	$2879*	$3349*
See Offers	$1449*	$2159*	$2879*	$3349*
	$1449*	$2159*	$2809*	$3349*
See Offers	$1449*	$2159*	$2879*	$3349*

Ports

Buenos Aires, Argentina
Montevideo, Uruguay
Port Stanley, Falkland Islands
Cruise Cape Horn
Ushuaia, Tierra Del Fuego, Argentina
Cruise Beagle Channel
Cruise Glacier Alley
Cruise Strait Of Magellan
Punta Arenas, Chile
Cruise Cockburn Channel
Puerto Montt, Chile
San Antonio, Chile
Coquimbo (La Serena), Chile
General San Martin (Pisco), Peru
Callao (Lima), Peru
Salaverry (Trujillo), Peru
Manta, Ecuador
Fuerte Amador, Panama
Panama Canal Transit
George Town, Grand Cayman
Ft. Lauderdale (Port Everglades), Florida

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Ports

Buenos Aires, Argentina - Montevideo, Uruguay - Port Stanley, Falkland Islands - Cruise Cape Horn - Ushuaia, Tierra Del Fuego, Argentina - Cruise Beagle Channel - Cruise Glacier Alley - Cruise Strait Of Magellan - Punta Arenas, Chile - Cruise Cockburn Channel - Puerto Montt, Chile - San Antonio, Chile - Coquimbo (La Serena), Chile - General San Martin (Pisco), Peru - Callao (Lima), Peru - Salaverry (Trujillo), Peru - Manta, Ecuador - Fuerte Amador, Panama - Panama Canal Transit - George Town, Grand Cayman - Ft. Lauderdale (Port Everglades), Florida - View more ports

31 Night South America Inca & Panama Canal Discovery (Buenos Aires To Ft. Lauderdale)

Oosterdam M

4.1

(870 Reviews)

2025 sail dates: Mar 05

2026 sail dates: Mar 08

$2559*

$83/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$2559*	$2749*	$4409*	$6979*
	$2559*	$2749*	$4409*	$6979*
See Offers	$2559*	$2749*	$4409*	$6979*
See Offers	$2649*	$2839*	$4409*	$6979*
See Offers	$2649*	$2839*	$4409*	$6979*
See Offers	$2649*	$2839*	$4409*	$6979*
See Offers	$2559*	$2749*	$4409*	$6979*
See Offers	$2559*	$2749*	$4409*	$6979*
See Offers	$2559*	$2749*	$4409*	$6979*
	$2649*	$2839*	$4409*	$6979*
	$3344*	$3744*	$5344*	$8044*
	$3344*	$3744*	$5344*	$8044*
	$3344*	$3744*	$5344*	$8044*
	$3344*	$3744*	$5344*	$8044*
	$3344*	$3744*	$5344*	$8044*
See Offers	$3344*	$3744*	$5344*	$8044*
See Offers	$3344*	$3744*	$5344*	$8044*
See Offers	$3344*	$3744*	$5344*	$8044*
	$3344*	$3744*	$5344*	$8044*

Ports

San Pedro (Los Angeles), California
Cabo San Lucas, Mexico
Puerto Vallarta, Mexico
Acapulco, Mexico
Puerto Quetzal, Guatemala
Panama City, Panama
Panama Canal Transit
Cartagena, Colombia
George Town, Grand Cayman
Miami, Florida

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Ports

San Pedro (Los Angeles), California - Cabo San Lucas, Mexico - Puerto Vallarta, Mexico - Acapulco, Mexico - Puerto Quetzal, Guatemala - Panama City, Panama - Panama Canal Transit - Cartagena, Colombia - George Town, Grand Cayman - Miami, Florida - View more ports

16 Night Panama Canal: Mexico & Colombia (Los Angeles To Miami)

Norwegian Joy L

4.2

(850 Reviews)

2025 sail dates: Jan 05

$1129*

$71/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1129*	$1519*	$2129*	$6349*
See Offers	$1129*	$1519*	$2129*	$2569*
See Offers	$1129*	$1519*	$2129*	$2569*
See Offers	$1129*	$1519*	$2129*	$2569*
See Offers	$1129*	$1519*	$2129*	$2569*
	$1129*	$1519*	$2128*	$2568*
See Offers	$1129*	$1519*	$2129*	$2569*
See Offers	$1129*	$1519*	$2129*	$2569*
See Offers	$1129*	$1519*	$2129*	$2569*
	$1129*	$1519*	$2129*	$2569*
See Offers	$1129*	$1519*	$2129*	$2569*

Ports

Miami, Florida
Cartagena, Colombia
Panama City, Panama
Panama Canal Transit
Puntarenas, Costa Rica
Puerto Quetzal, Guatemala
Acapulco, Mexico
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Pedro (Los Angeles), California
San Francisco, California
Victoria, British Columbia
Seattle, Washington

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Ports

Miami, Florida - Cartagena, Colombia - Panama City, Panama - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Acapulco, Mexico - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - San Francisco, California - Victoria, British Columbia - Seattle, Washington - View more ports

22 Night Panama Canal: Mexico & Costa Rica (Miami To Seattle)

Norwegian Encore XL

4.3

(640 Reviews)

2026 sail dates: Apr 11

$2109*

$96/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$2109*	$2989*	$3959*	$11549*
See Offers	$2109*	$2989*	$3959*	$4649*
See Offers	$2109*	$2989*	$3959*	$4649*
See Offers	$2109*	$2989*	$3959*	$4649*
	$2109*	$2988*	$3959*	$4648*
See Offers	$2109*	$2989*	$3959*	$4649*
See Offers	$2109*	$2989*	$3959*	$4649*
See Offers	$2109*	$2989*	$3959*	$4649*
	$2109*	$2989*	$3959*	$4649*
See Offers	$2109*	$2989*	$3959*	$4649*

Ports

Ft. Lauderdale (Port Everglades), Florida
George Town, Grand Cayman
Panama Canal Transit
Fuerte Amador, Panama
Cross The Equator
Manta, Ecuador
Salaverry (Trujillo), Peru
Callao (Lima), Peru
General San Martin (Pisco), Peru
Coquimbo (La Serena), Chile
San Antonio, Chile

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Ports

Ft. Lauderdale (Port Everglades), Florida - George Town, Grand Cayman - Panama Canal Transit - Fuerte Amador, Panama - Cross The Equator - Manta, Ecuador - Salaverry (Trujillo), Peru - Callao (Lima), Peru - General San Martin (Pisco), Peru - Coquimbo (La Serena), Chile - San Antonio, Chile - View more ports

17 Night Panama Canal & Inca Discovery (Ft. Lauderdale To San Antonio)

Oosterdam M

4.1

(870 Reviews)

2024 sail dates: Nov 14

2025 sail dates: Nov 17

$999*

$59/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$999*	$1099*	$1879*	$2979*
	$999*	$1099*	$1879*	$2979*
See Offers	$999*	$1099*	$1879*	$2979*
See Offers	$999*	$1099*	$1879*	$2979*
See Offers	$999*	$1099*	$1879*	$2979*
See Offers	$999*	$1099*	$1879*	$2979*
See Offers	$999*	$1099*	$1879*	$2979*
See Offers	$999*	$1099*	$1879*	$2979*
	$999*	$1099*	$1879*	$2979*
	$1764*	$2014*	$2764*	$4364*
	$2784*	$2314*	$3784*	$5384*
See Offers	$1764*	$2014*	$2764*	$4364*
See Offers	$1764*	$2014*	$2764*	$4364*
See Offers	$1764*	$2014*	$2764*	$4364*
See Offers	$2784*	$2314*	$3784*	$5384*
See Offers	$2784*	$2314*	$3784*	$5384*
See Offers	$2784*	$2314*	$3784*	$5384*
	$1764*	$2014*	$2764*	$4364*

Ports

San Pedro (Los Angeles), California
Cabo San Lucas, Mexico
Puerto Vallarta, Mexico
Manzanillo, Mexico
Puerto Quetzal, Guatemala
Puntarenas, Costa Rica
Panama City, Panama
Panama Canal Transit
Cartagena, Colombia
Miami, Florida

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Ports

San Pedro (Los Angeles), California - Cabo San Lucas, Mexico - Puerto Vallarta, Mexico - Manzanillo, Mexico - Puerto Quetzal, Guatemala - Puntarenas, Costa Rica - Panama City, Panama - Panama Canal Transit - Cartagena, Colombia - Miami, Florida - View more ports

15 Night Panama Canal: Mexico & Colombia (Los Angeles To Miami)

Norwegian Bliss XL

4.1

(1281 Reviews)

2024 sail dates: Dec 06

$999*

$67/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$999*	$1329*	$1949*	$7599*
See Offers	$999*	$1329*	$1949*	$1859*
See Offers	$999*	$1329*	$1949*	$2129*
See Offers	$999*	$1329*	$1949*	$1859*
See Offers	$999*	$1329*	$1949*	$1859*
	$999*	$1329*	$1949*	$2129*
See Offers	$999*	$1329*	$1949*	$2129*
See Offers	$999*	$1329*	$1949*	$2129*
See Offers	$999*	$1329*	$1949*	$2129*
	$999*	$1329*	$1949*	$1859*
See Offers	$879*	$1209*	$1749*	$1929*

Ports

Ft. Lauderdale (Port Everglades), Florida
Kralendijk, Bonaire
Oranjestad, Aruba
Cartagena, Colombia
Colon, Panama
Panama Canal (Cruise Into Canal)
Puerto Limon, Costa Rica
George Town, Grand Cayman

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Ports

Ft. Lauderdale (Port Everglades), Florida - Kralendijk, Bonaire - Oranjestad, Aruba - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports

12 Night Panama Canal With Costa Rica & Caribbean (Ft. Lauderdale Roundtrip)

Emerald Princess L

4.0

(1165 Reviews)

2024 sail dates: Dec 06

2025 sail dates: Feb 28

$597*

$50/night*

Inside

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$597*	$927*	$1397*	$3698*
	$598*	$698*	$1398*	$1798*
See Offers	$598*	$698*	$1398*	$1798*
See Offers	$598*	$698*	$1398*	$1798*
See Offers	$598*	$698*	$1398*	$1798*
See Offers	$598*	$698*	$1398*	$1798*
See Offers	$598*	$698*	$1398*	$1798*
See Offers	$598*	$698*	$1398*	$1798*
See Offers	$598*	$698*	$1398*	$1798*
	$598*	$698*	$1398*	$1798*
	$727*	$1147*	$1647*	$4696*
See Offers	$728*	$837*	$1648*	$2148*
	$728*	$837*	$1648*	$2148*
See Offers	$728*	$837*	$1648*	$2148*
See Offers	$728*	$837*	$1648*	$2148*
See Offers	$728*	$837*	$1648*	$2148*
See Offers	$728*	$837*	$1648*	$2148*
See Offers	$728*	$837*	$1648*	$2148*
See Offers	$728*	$837*	$1648*	$2148*
See Offers	$728*	$837*	$1648*	$2148*
	$728*	$837*	$1648*	$2148*

Ports

Miami, Florida
Cartagena, Colombia
Panama City, Panama
Panama Canal Transit
Puerto Caldera, Costa Rica
Puerto Quetzal, Guatemala
Manzanillo, Mexico
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Pedro (Los Angeles), California
San Francisco, California
Victoria, British Columbia
Seattle, Washington

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Ports

Miami, Florida - Cartagena, Colombia - Panama City, Panama - Panama Canal Transit - Puerto Caldera, Costa Rica - Puerto Quetzal, Guatemala - Manzanillo, Mexico - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - San Francisco, California - Victoria, British Columbia - Seattle, Washington - View more ports

21 Night Panama Canal: Mexico Columbia & Guatemala (Miami To Seattle)

Norwegian Encore XL

4.3

(640 Reviews)

2025 sail dates: Mar 30

$1599*

$76/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1599*	$2379*	$2999*	$10279*
See Offers	$1599*	$2379*	$2999*	$3449*
See Offers	$1599*	$2379*	$2999*	$3449*
See Offers	$1599*	$2379*	$2999*	$3449*
See Offers	$1599*	$2379*	$2999*	$3449*
	$1599*	$2379*	$2999*	$3448*
See Offers	$1599*	$2379*	$2999*	$3449*
See Offers	$1599*	$2379*	$2999*	$3449*
See Offers	$1599*	$2379*	$2999*	$3449*
	$1599*	$2379*	$2999*	$3449*
See Offers	$1599*	$2379*	$2999*	$3449*

Ports

Ft. Lauderdale (Port Everglades), Florida
Oranjestad, Aruba
Kralendijk, Bonaire
Cartagena, Colombia
Colon, Panama
Panama Canal (Cruise Into Canal)
Puerto Limon, Costa Rica
George Town, Grand Cayman

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Ports

Ft. Lauderdale (Port Everglades), Florida - Oranjestad, Aruba - Kralendijk, Bonaire - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports

12 Night Panama Canal With Costa Rica & Caribbean (Ft. Lauderdale Roundtrip)

Emerald Princess L

4.0

(1165 Reviews)

2025 sail dates: Jan 11, Jan 23

$797*

$66/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$797*	$1397*	$1797*	$4957*
See Offers	$798*	$931*	$1798*	$2248*
	$798*	$931*	$1798*	$2248*
See Offers	$798*	$931*	$1798*	$2248*
See Offers	$798*	$931*	$1798*	$2248*
See Offers	$798*	$931*	$1798*	$2248*
See Offers	$798*	$931*	$1798*	$2248*
See Offers	$798*	$931*	$1798*	$2248*
See Offers	$798*	$931*	$1798*	$2248*
See Offers	$798*	$931*	$1798*	$2248*
	$798*	$931*	$1798*	$2248*
	$847*	$1397*	$1797*	$4817*
See Offers	$848*	$976*	$1798*	$2398*
	$848*	$976*	$1798*	$1989*
See Offers	$848*	$976*	$1798*	$2398*
See Offers	$848*	$976*	$1798*	$2398*
See Offers	$848*	$976*	$1798*	$2398*
See Offers	$848*	$976*	$1798*	$1989*
See Offers	$848*	$976*	$1798*	$1989*
See Offers	$848*	$976*	$1798*	$1989*
See Offers	$848*	$976*	$1798*	$1989*
	$848*	$976*	$1798*	$2398*

Panama Canal, Central America cruises 322 Panama Canal, Central America Cruises Found

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