Panama Canal, Central America Cruises : Best Cruise Prices

Sponsored cruise

Ports

Miami, Florida
George Town, Grand Cayman
Cartagena, Colombia
Panama Canal (Cruise Into Canal)
Colon, Panama
Puerto Limon, Costa Rica
Harvest Caye, Belize
Cozumel, Mexico

Ports

Miami, Florida - George Town, Grand Cayman - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - Harvest Caye, Belize - Cozumel, Mexico - View more ports

11 Night Panama Canal: Mexico Costa Rica & Belize (Miami Roundtrip)

Norwegian Gem L

3.8

(2493 Reviews)

2025 sail dates: Jan 03

$1091*

$99/night*

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Sponsored cruise

Ports

New York, New York
Ft. Lauderdale (Port Everglades), Florida
Philipsburg, St. Maarten
Castries, St. Lucia
Bridgetown, Barbados
Devils Island, French Guiana
Cruise Amazon River
CRUISE BARRA NORTE RIVER
Macapa, Brazil
Cross The Equator
Santarem, Brazil
Boca Da Valeria, Brazil
Manaus, Brazil
Parintins, Brazil
Alter Do Chao, Brazil
Port of Spain
Willemstad, Curacao
Oranjestad, Aruba

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Ports

New York, New York - Ft. Lauderdale (Port Everglades), Florida - Philipsburg, St. Maarten - Castries, St. Lucia - Bridgetown, Barbados - Devils Island, French Guiana - Cruise Amazon River - CRUISE BARRA NORTE RIVER - Macapa, Brazil - Cross The Equator - Santarem, Brazil - Boca Da Valeria, Brazil - Manaus, Brazil - Parintins, Brazil - Alter Do Chao, Brazil - Port of Spain - Willemstad, Curacao - Oranjestad, Aruba - View more ports

30 Night Amazon Explorer (New York To Ft. Lauderdale)

Volendam M

4.0

(296 Reviews)

2025 sail dates: Nov 21

$5284*

$176/night*

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Ports

Ft. Lauderdale (Port Everglades), Florida
Oranjestad, Aruba
Panama Canal Transit
PANAMA CITY (FUERTE AMADOR), PANAMA
Puntarenas, Costa Rica
Puerto Chiapas (Tapachula), Mexico
Huatulco, Mexico
Puerto Vallarta, Mexico
San Pedro (Los Angeles), California

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Ports

Ft. Lauderdale (Port Everglades), Florida - Oranjestad, Aruba - Panama Canal Transit - PANAMA CITY (FUERTE AMADOR), PANAMA - Puntarenas, Costa Rica - Puerto Chiapas (Tapachula), Mexico - Huatulco, Mexico - Puerto Vallarta, Mexico - San Pedro (Los Angeles), California - View more ports

16 Night Panama Canal - Ocean To Ocean (Ft. Lauderdale To Los Angeles)

Grand Princess L

4.0

(1103 Reviews)

2026 sail dates: Apr 16

$1818*

$114/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1818*	$2268*	$2638*	N/A
See Offers	$1818*	$2027*	$2638*	$3688*
	$1818*	$2027*	$2638*	$3688*
See Offers	$1818*	$2027*	$2638*	$3688*
See Offers	$1818*	$2027*	$2638*	$3688*
See Offers	$1818*	$2027*	$2638*	$3688*
See Offers	$1818*	$2027*	$2638*	$3688*

Ports

PANAMA CITY (FUERTE AMADOR), PANAMA
Panama Canal Transit
Cartagena, Colombia
Puerto Limon, Costa Rica
Coxen Hole, Roatan, Bay Islands, Honduras
Costa Maya (Mahahual), Mexico
Cozumel, Mexico
Miami, Florida

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Ports

PANAMA CITY (FUERTE AMADOR), PANAMA - Panama Canal Transit - Cartagena, Colombia - Puerto Limon, Costa Rica - Coxen Hole, Roatan, Bay Islands, Honduras - Costa Maya (Mahahual), Mexico - Cozumel, Mexico - Miami, Florida - View more ports

10 Night Canal & Coral Isles (Panama City To Miami)

Insignia S

4.1

(88 Reviews)

2026 sail dates: Apr 24

$2999*

$300/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$2999*	$3299*	$4899*	$6799*
See Offers	$2999*	$3299*	$4899*	$6799*
See Offers	$2999*	$3299*	$4899*	$6799*
	$2999*	$3299*	$4899*	$6799*
See Offers	$2999*	$3299*	$4899*	$6799*
See Offers	$2999*	$3299*	$4899*	$6799*

Ports

Seattle, Washington
San Diego, California
Cabo San Lucas, Mexico
Puntarenas, Costa Rica
Panama Canal Transit
Cartagena, Colombia
Miami, Florida

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Ports

Seattle, Washington - San Diego, California - Cabo San Lucas, Mexico - Puntarenas, Costa Rica - Panama Canal Transit - Cartagena, Colombia - Miami, Florida - View more ports

20 Night Coastal West & Panama Canal (Seattle To Miami)

Silver Nova M

4.1

(7 Reviews)

2026 sail dates: May 11

$12400*

$620/night*

Suite

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	N/A	N/A	N/A	$12400*
See Offers	N/A	N/A	N/A	$12400*
	N/A	N/A	N/A	$12400*
See Offers	N/A	N/A	N/A	$12400*

Ports

Vancouver (Canada Place), British Columbia
Santa Barbara, California
Long Beach (Los Angeles), California
Puerto Vallarta, Mexico
Huatulco, Mexico
Puerto Chiapas (Tapachula), Mexico
Puerto Quetzal, Guatemala
Puntarenas, Costa Rica
Panama Canal Transit
Cartagena, Colombia
Miami, Florida

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Ports

Vancouver (Canada Place), British Columbia - Santa Barbara, California - Long Beach (Los Angeles), California - Puerto Vallarta, Mexico - Huatulco, Mexico - Puerto Chiapas (Tapachula), Mexico - Puerto Quetzal, Guatemala - Puntarenas, Costa Rica - Panama Canal Transit - Cartagena, Colombia - Miami, Florida - View more ports

24 Night Panama Canal Passage (Vancouver To Miami)

Seabourn Sojourn S

4.4

(42 Reviews)

2026 sail dates: May 15

$9399*

$392/night*

Suite

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	N/A	N/A	N/A	$9399*
See Offers	N/A	N/A	N/A	$9399*
	N/A	N/A	N/A	$9399*
See Offers	N/A	N/A	N/A	$9399*

Ports

Long Beach (Los Angeles), California
Puerto Vallarta, Mexico
Huatulco, Mexico
Puerto Chiapas (Tapachula), Mexico
Puerto Quetzal, Guatemala
Puntarenas, Costa Rica
Panama Canal Transit
Cartagena, Colombia
Miami, Florida

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Ports

Long Beach (Los Angeles), California - Puerto Vallarta, Mexico - Huatulco, Mexico - Puerto Chiapas (Tapachula), Mexico - Puerto Quetzal, Guatemala - Puntarenas, Costa Rica - Panama Canal Transit - Cartagena, Colombia - Miami, Florida - View more ports

19 Night Panama Canal Passage (Long Beach To Miami)

Seabourn Sojourn S

4.4

(42 Reviews)

2026 sail dates: May 20

$8399*

$442/night*

Suite

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	N/A	N/A	N/A	$8399*
See Offers	N/A	N/A	N/A	$8399*
	N/A	N/A	N/A	$8399*
See Offers	N/A	N/A	N/A	$8399*

Ports

Vancouver (Canada Place), British Columbia
Victoria, British Columbia
San Francisco, California
San Pedro (Los Angeles), California
Cabo San Lucas, Mexico
Mazatlan, Mexico
PANAMA CITY (FUERTE AMADOR), PANAMA
Panama Canal Transit
Oranjestad, Aruba
Ft. Lauderdale (Port Everglades), Florida

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Ports

Vancouver (Canada Place), British Columbia - Victoria, British Columbia - San Francisco, California - San Pedro (Los Angeles), California - Cabo San Lucas, Mexico - Mazatlan, Mexico - PANAMA CITY (FUERTE AMADOR), PANAMA - Panama Canal Transit - Oranjestad, Aruba - Ft. Lauderdale (Port Everglades), Florida - View more ports

23 Night Panama Canal & Pacific Coast (Vancouver To Ft. Lauderdale)

Star Princess XL

2026 sail dates: Sep 27

$2883*

$125/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$2883*	$3558*	N/A	$17378*
See Offers	$2883*	$3558*	$5468*	$8778*
	$2883*	$3558*	$5468*	$8778*
See Offers	$2883*	$3558*	$5468*	$8778*
See Offers	$2883*	$3558*	$5468*	$8778*
See Offers	$2883*	$3558*	$5468*	$8778*
See Offers	$2883*	$3558*	$5468*	$8778*

Ports

San Pedro (Los Angeles), California
Cabo San Lucas, Mexico
Mazatlan, Mexico
PANAMA CITY (FUERTE AMADOR), PANAMA
Panama Canal Transit
Oranjestad, Aruba
Ft. Lauderdale (Port Everglades), Florida

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Ports

San Pedro (Los Angeles), California - Cabo San Lucas, Mexico - Mazatlan, Mexico - PANAMA CITY (FUERTE AMADOR), PANAMA - Panama Canal Transit - Oranjestad, Aruba - Ft. Lauderdale (Port Everglades), Florida - View more ports

16 Night Panama Canal - Ocean To Ocean (Los Angeles To Ft. Lauderdale)

Star Princess XL

2026 sail dates: Oct 04

$1649*

$103/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1649*	$2299*	N/A	$12739*
See Offers	$1649*	$2299*	$3759*	$6649*
	$1649*	$2299*	$3759*	$6649*
See Offers	$1649*	$2299*	$3759*	$6649*
See Offers	$1649*	$2299*	$3759*	$6649*
See Offers	$1649*	$2299*	$3759*	$6649*
See Offers	$1649*	$2299*	$3759*	$6649*

Ports

Seattle, Washington
Cabo San Lucas, Mexico
Puntarenas, Costa Rica
Panama Canal Transit
Cartagena, Colombia
Mobile, Alabama

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Ports

Seattle, Washington - Cabo San Lucas, Mexico - Puntarenas, Costa Rica - Panama Canal Transit - Cartagena, Colombia - Mobile, Alabama - View more ports

16 Night Carnival Journeys: Panama Canal (Seattle To Mobile)

Carnival Spirit L

4.0

(977 Reviews)

2026 sail dates: Oct 08

$1524*

$95/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1524*	$1884*	$2354*	$3608*
	$1524*	$1884*	$2354*	$3608*
See Offers	$1524*	$1884*	$2354*	$3608*
See Offers	$1524*	$1884*	$2354*	$3608*
	$1515*	$1875*	$2345*	$3599*

Ports

New York, New York
San Salvador, Bahamas
Great Inagua, Bahamas
Port Antonio, Jamaica
Panama Canal Transit
PANAMA CITY (FUERTE AMADOR), PANAMA
Callao (Lima), Peru
Iquique, Chile
Valparaiso (Santiago), Chile

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Ports

New York, New York - San Salvador, Bahamas - Great Inagua, Bahamas - Port Antonio, Jamaica - Panama Canal Transit - PANAMA CITY (FUERTE AMADOR), PANAMA - Callao (Lima), Peru - Iquique, Chile - Valparaiso (Santiago), Chile - View more ports

19 Night Panama Canal & The Americas (New York To Santiago)

Viking Polaris S

4.2

(8 Reviews)

2026 sail dates: Oct 25

$10995*

$579/night*

Balcony

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	N/A	N/A	$10995*	$15995*
See Offers	N/A	N/A	$10995*	$15995*
	N/A	N/A	$10995*	$15995*

Ports

Ft. Lauderdale (Port Everglades), Florida
Cartagena, Colombia
Colon, Panama
Panama Canal (Cruise Into Canal)
Oranjestad, Aruba
Willemstad, Curacao
Kralendijk, Bonaire

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Ports

Ft. Lauderdale (Port Everglades), Florida - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Oranjestad, Aruba - Willemstad, Curacao - Kralendijk, Bonaire - View more ports

11 Night Panama Canal & Southern Caribbean (Ft. Lauderdale Roundtrip)

Celebrity Ascent L

4.6

(73 Reviews)

2026 sail dates: Nov 23

2027 sail dates: Mar 08

$2211*

$201/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$2211*	$2411*	$2751*	$7277*
See Offers	$2211*	$2411*	$2751*	$7276*
	$2211*	$2411*	$2751*	$7276*
See Offers	$2211*	$2411*	$2751*	$7277*
See Offers	$2211*	$2411*	$2751*	$7277*
See Offers	$2211*	$2411*	$2751*	$7277*
See Offers	$2211*	$2411*	$2751*	$7277*
See Offers	$2211*	$2411*	$2751*	$7276*
	$2212*	$2412*	$2752*	$7278*
See Offers	$2212*	$2412*	$2752*	$7277*
	$2212*	$2412*	$2752*	$7277*
See Offers	$2212*	$2412*	$2752*	$7278*
See Offers	$2212*	$2412*	$2752*	$7278*
See Offers	$2212*	$2412*	$2752*	$7278*
See Offers	$2212*	$2412*	$2752*	$7278*
See Offers	$2212*	$2412*	$2752*	$7277*

Panama Canal, Central America cruises 384 Panama Canal, Central America Cruises Found

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