Panama Canal, Central America Cruises : Best Cruise Prices

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Ports

New York, New York
Ft. Lauderdale (Port Everglades), Florida
Philipsburg, St. Maarten
Castries, St. Lucia
Bridgetown, Barbados
Devils Island, French Guiana
Cruise Amazon River
CRUISE BARRA NORTE RIVER
Macapa, Brazil
Cross The Equator
Santarem, Brazil
Boca Da Valeria, Brazil
Manaus, Brazil
Parintins, Brazil
Alter Do Chao, Brazil
Port of Spain
Willemstad, Curacao
Oranjestad, Aruba

Ports

New York, New York - Ft. Lauderdale (Port Everglades), Florida - Philipsburg, St. Maarten - Castries, St. Lucia - Bridgetown, Barbados - Devils Island, French Guiana - Cruise Amazon River - CRUISE BARRA NORTE RIVER - Macapa, Brazil - Cross The Equator - Santarem, Brazil - Boca Da Valeria, Brazil - Manaus, Brazil - Parintins, Brazil - Alter Do Chao, Brazil - Port of Spain - Willemstad, Curacao - Oranjestad, Aruba - View more ports

30 Night Amazon Explorer (New York To Ft. Lauderdale)

Volendam M

4.0

(293 Reviews)

2025 sail dates: Nov 21

$5584*

$186/night*

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Ports

Ft. Lauderdale (Port Everglades), Florida
George Town, Grand Cayman
Puerto Limon, Costa Rica
Colon, Panama
Panama Canal (Cruise Into Canal)
Oranjestad, Aruba
Willemstad, Curacao

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Ports

Ft. Lauderdale (Port Everglades), Florida - George Town, Grand Cayman - Puerto Limon, Costa Rica - Colon, Panama - Panama Canal (Cruise Into Canal) - Oranjestad, Aruba - Willemstad, Curacao - View more ports

12 Night Panama Canal With Costa Rica & Caribbean (Ft. Lauderdale Roundtrip)

Emerald Princess L

4.0

(1196 Reviews)

2024 sail dates: Dec 18

$969*

$81/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$969*	$1239*	$1684*	$5223*
See Offers	$969*	$1027*	$1639*	$2439*
See Offers	$969*	$1027*	$1684*	$2439*
See Offers	$969*	$1027*	$1684*	$2439*
See Offers	$969*	$1027*	$1684*	$2439*
	$969*	$1027*	$1684*	$2439*
See Offers	$969*	$1027*	$1684*	$2439*

Ports

Ft. Lauderdale (Port Everglades), Florida
Cartagena, Colombia
Panama Canal Transit
PANAMA CITY (FUERTE AMADOR), PANAMA
Puntarenas, Costa Rica
Puerto Quetzal, Guatemala
Manzanillo, Mexico
San Francisco, California

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Ports

Ft. Lauderdale (Port Everglades), Florida - Cartagena, Colombia - Panama Canal Transit - PANAMA CITY (FUERTE AMADOR), PANAMA - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Manzanillo, Mexico - San Francisco, California - View more ports

16 Night Panama Canal - Ocean To Ocean Holiday (Ft. Lauderdale To San Francisco)

Island Princess M

4.0

(905 Reviews)

2025 sail dates: Nov 21

$1788*

$112/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1788*	$2408*	$2758*	$6459*
See Offers	$1788*	$1964*	$2713*	$3115*
See Offers	$1789*	$1965*	$2713*	$3115*
See Offers	$1789*	$1965*	$2713*	$3115*
See Offers	$1788*	$1964*	$2713*	$3115*
	$1789*	$1965*	$2713*	$3115*
See Offers	$1788*	$1964*	$2713*	$3115*

Ports

San Francisco, California
Puerto Vallarta, Mexico
Puerto Quetzal, Guatemala
Puntarenas, Costa Rica
PANAMA CITY (FUERTE AMADOR), PANAMA
Panama Canal Transit
Cartagena, Colombia
Ft. Lauderdale (Port Everglades), Florida

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Ports

San Francisco, California - Puerto Vallarta, Mexico - Puerto Quetzal, Guatemala - Puntarenas, Costa Rica - PANAMA CITY (FUERTE AMADOR), PANAMA - Panama Canal Transit - Cartagena, Colombia - Ft. Lauderdale (Port Everglades), Florida - View more ports

16 Night Panama Canal - Ocean To Ocean (San Francisco To Ft. Lauderdale)

Island Princess M

4.0

(905 Reviews)

2025 sail dates: Dec 07

$1749*

$109/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1749*	$2149*	$2549*	$6249*
See Offers	$1749*	$1920*	$2507*	$3032*
See Offers	$1948*	$2119*	$2707*	$3232*
See Offers	$1948*	$2119*	$2707*	$3232*
See Offers	$1749*	$1920*	$2507*	$3032*
	$1948*	$2119*	$2707*	$3232*
See Offers	$1749*	$1920*	$2507*	$3032*

Ports

Ft. Lauderdale (Port Everglades), Florida
Cartagena, Colombia
Panama Canal Transit
PANAMA CITY (FUERTE AMADOR), PANAMA
Puntarenas, Costa Rica
San Juan Del Sur, Nicaragua
Huatulco, Mexico
Puerto Vallarta, Mexico
San Pedro (Los Angeles), California

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Ports

Ft. Lauderdale (Port Everglades), Florida - Cartagena, Colombia - Panama Canal Transit - PANAMA CITY (FUERTE AMADOR), PANAMA - Puntarenas, Costa Rica - San Juan Del Sur, Nicaragua - Huatulco, Mexico - Puerto Vallarta, Mexico - San Pedro (Los Angeles), California - View more ports

16 Night Panama Canal - Ocean To Ocean (Ft. Lauderdale To Los Angeles)

Island Princess M

4.0

(905 Reviews)

2026 sail dates: Jan 24

$1778*

$111/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1778*	$2388*	$2858*	$6359*
See Offers	$1778*	$1953*	$2858*	$3187*
See Offers	$1778*	$1953*	$2858*	$3187*
See Offers	$1778*	$1953*	$2858*	$3187*
See Offers	$1778*	$1953*	$2858*	$3187*
	$1778*	$1953*	$2858*	$3187*
See Offers	$1778*	$1953*	$2858*	$3187*

Ports

Ft. Lauderdale (Port Everglades), Florida
Kralendijk, Bonaire
Willemstad, Curacao
Cartagena, Colombia
Panama Canal (Cruise Into Canal)
Colon, Panama
Puerto Limon, Costa Rica
George Town, Grand Cayman

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Ports

Ft. Lauderdale (Port Everglades), Florida - Kralendijk, Bonaire - Willemstad, Curacao - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports

12 Night Panama Canal With Costa Rica & Caribbean (Ft. Lauderdale Roundtrip)

Emerald Princess L

4.0

(1196 Reviews)

2025 sail dates: Feb 28

$1149*

$96/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1149*	$1699*	$2299*	N/A
See Offers	$1149*	$1270*	$2299*	$3195*
See Offers	$1348*	$1469*	$2498*	$3395*
See Offers	$1348*	$1469*	$2498*	$3395*
See Offers	$1149*	$1270*	$2299*	$3195*
	$1348*	$1469*	$2498*	$3395*
See Offers	$1149*	$1270*	$2299*	$3195*

Ports

Boston, Massachusetts
King's Wharf, Bermuda
Half Moon Cay, Bahamas (Private Island)
Grand Turk Island
Willemstad, Curacao
Oranjestad, Aruba
St. George's, Grenada
Bridgetown, Barbados
Fort-De-France, Martinique
Pointe-A-Pitre, Guadeloupe
Basseterre, St. Kitts
Philipsburg, St. Maarten
San Juan, Puerto Rico

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Ports

Boston, Massachusetts - King's Wharf, Bermuda - Half Moon Cay, Bahamas (Private Island) - Grand Turk Island - Willemstad, Curacao - Oranjestad, Aruba - St. George's, Grenada - Bridgetown, Barbados - Fort-De-France, Martinique - Pointe-A-Pitre, Guadeloupe - Basseterre, St. Kitts - Philipsburg, St. Maarten - San Juan, Puerto Rico - View more ports

21 Night Perfect Caribbean Escape (Boston Roundtrip)

Zuiderdam M

4.0

(743 Reviews)

2024 sail dates: Oct 19

$2454*

$117/night*

Oceanview

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	N/A	$2454*	$3154*	$4954*
	N/A	$2454*	$3154*	$4954*
See Offers	N/A	$2454*	$3154*	$4954*

Ports

Ft. Lauderdale (Port Everglades), Florida
Grand Turk Island
Oranjestad, Aruba
Cartagena, Colombia
Panama Canal Transit
Puerto Caldera, Costa Rica
Acajutla
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Diego, California
Victoria, British Columbia
Vancouver (Canada Place), British Columbia

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Ports

Ft. Lauderdale (Port Everglades), Florida - Grand Turk Island - Oranjestad, Aruba - Cartagena, Colombia - Panama Canal Transit - Puerto Caldera, Costa Rica - Acajutla - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Diego, California - Victoria, British Columbia - Vancouver (Canada Place), British Columbia - View more ports

21 Night Panama Canal (Ft. Lauderdale To Vancouver)

Nieuw Amsterdam L

4.1

(784 Reviews)

2025 sail dates: Apr 13

$1894*

$90/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1894*	$2094*	$3594*	$6394*
See Offers	$2039*	$2239*	$3739*	$6539*
See Offers	$2039*	$2239*	$3739*	$6539*
	$2039*	$2239*	$3739*	$6539*
See Offers	$2039*	$2239*	$3739*	$6539*
See Offers	$2039*	$2239*	$3739*	$6539*
See Offers	$2039*	$2239*	$3739*	$6539*

Ports

Miami, Florida
George Town, Grand Cayman
Cartagena, Colombia
Colon, Panama
Cruise Gatun Lake And Panama Canal
Puerto Limon, Costa Rica
Harvest Caye, Belize
Cozumel, Mexico

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Ports

Miami, Florida - George Town, Grand Cayman - Cartagena, Colombia - Colon, Panama - Cruise Gatun Lake And Panama Canal - Puerto Limon, Costa Rica - Harvest Caye, Belize - Cozumel, Mexico - View more ports

11 Night Panama Canal: Mexico Costa Rica & Belize (Miami Roundtrip)

Norwegian Jade L

3.9

(1393 Reviews)

2025 sail dates: Nov 20, Dec 01

$1780*

$162/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1879*	$2180*	$3159*	$8449*
See Offers	$1879*	$2180*	$3159*	$3409*
See Offers	$1879*	$2180*	$3159*	$3409*
See Offers	$1880*	$2180*	$3160*	$3410*
See Offers	$1879*	$2180*	$3159*	$3409*
	$1879*	$2180*	$3159*	$3409*
See Offers	$1880*	$2180*	$3160*	$3410*
See Offers	$1879*	$2180*	$3159*	$3409*
See Offers	$1879*	$2180*	$3159*	$3409*
See Offers	$1780*	$2130*	$3030*	$8249*
See Offers	$1780*	$2130*	$3030*	$3359*
See Offers	$1780*	$2130*	$3030*	$3359*
See Offers	$1780*	$2130*	$3030*	$3359*
See Offers	$1780*	$2130*	$3030*	$3359*
	$1780*	$2130*	$3030*	$3359*
See Offers	$1780*	$2130*	$3030*	$3359*
See Offers	$1780*	$2130*	$3030*	$3359*
See Offers	$1780*	$2130*	$3030*	$3359*

Ports

Ft. Lauderdale (Port Everglades), Florida
George Town, Grand Cayman
Falmouth, Jamaica
Puerto Limon, Costa Rica
Panama Canal (Cruise Into Canal)
Colon, Panama
Oranjestad, Aruba
Willemstad, Curacao

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Ports

Ft. Lauderdale (Port Everglades), Florida - George Town, Grand Cayman - Falmouth, Jamaica - Puerto Limon, Costa Rica - Panama Canal (Cruise Into Canal) - Colon, Panama - Oranjestad, Aruba - Willemstad, Curacao - View more ports

12 Night Panama Canal With Costa Rica & Caribbean (Ft. Lauderdale Roundtrip)

Caribbean Princess L

3.9

(1888 Reviews)

2025 sail dates: Nov 29

2026 sail dates: Feb 21

$1368*

$114/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1368*	$1668*	$2118*	$4689*
See Offers	$1368*	$1406*	$2118*	$2618*
See Offers	$1369*	$1407*	$2119*	$2619*
See Offers	$1369*	$1407*	$2119*	$2619*
See Offers	$1368*	$1406*	$2118*	$2618*
	$1369*	$1407*	$2119*	$2619*
See Offers	$1368*	$1406*	$2118*	$2618*
	$1568*	$2068*	$2498*	$5069*
See Offers	$1568*	$1613*	$2498*	$3018*
See Offers	$1568*	$1613*	$2498*	$3018*
See Offers	$1568*	$1613*	$2498*	$3018*
See Offers	$1568*	$1613*	$2498*	$3018*
	$1568*	$1613*	$2498*	$3018*
See Offers	$1568*	$1613*	$2498*	$3018*

Ports

Miami, Florida
Ocho Rios, Jamaica
Cartagena, Colombia
Colon, Panama
Cruise Gatun Lake And Panama Canal
Puerto Limon, Costa Rica
Harvest Caye, Belize
Cozumel, Mexico

View more ports

Ports

Miami, Florida - Ocho Rios, Jamaica - Cartagena, Colombia - Colon, Panama - Cruise Gatun Lake And Panama Canal - Puerto Limon, Costa Rica - Harvest Caye, Belize - Cozumel, Mexico - View more ports

11 Night Panama Canal: Mexico Costa Rica & Belize (Miami Roundtrip)

Norwegian Pearl L

3.8

(2045 Reviews)

2025 sail dates: Dec 22

2026 sail dates: Jan 02

$1816*

$165/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$2209*	$2609*	$4089*	$14159*
See Offers	$2209*	$2609*	$4089*	$4609*
See Offers	$2209*	$2609*	$4089*	$4609*
See Offers	$2209*	$2609*	$4089*	$4609*
See Offers	$2209*	$2609*	$4089*	$4609*
	$2209*	$2609*	$4089*	$4609*
See Offers	$2209*	$2609*	$4089*	$4609*
See Offers	$2209*	$2609*	$4089*	$4609*
See Offers	$2209*	$2609*	$4089*	$4609*
See Offers	$1816*	$2186*	$3266*	$8666*
See Offers	$1816*	$2186*	$3266*	$3466*
See Offers	$1816*	$2186*	$3266*	$3466*
See Offers	$1816*	$2186*	$3266*	$3466*
See Offers	$1816*	$2186*	$3266*	$3466*
	$1816*	$2186*	$3266*	$3466*
See Offers	$1816*	$2186*	$3266*	$3466*
See Offers	$1816*	$2186*	$3266*	$3466*
See Offers	$1816*	$2186*	$3266*	$3466*

Panama Canal, Central America cruises 330 Panama Canal, Central America Cruises Found

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