Cruises to Panama Canal, Central America leaving Miami, Florida cruise port 69 Panama Canal, Central America Cruises Found
Your search Clear selections
69 cruises found
Sort by
Filter by
Ports
- Miami, Florida
- George Town, Grand Cayman
- Cartagena, Colombia
- Panama Canal (Cruise Into Canal)
- Colon, Panama
- Puerto Limon, Costa Rica
- Harvest Caye, Belize
- Cozumel, Mexico
Ports
Miami, Florida - George Town, Grand Cayman - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - Harvest Caye, Belize - Cozumel, Mexico - View more ports
11 Night Panama Canal: Mexico Costa Rica & Belize (Miami Roundtrip)
2025 sail dates:
Ports
- Miami, Florida
- Cozumel, Mexico
- Harvest Caye, Belize
- Coxen Hole, Roatan, Bay Islands, Honduras
- George Town, Grand Cayman
- Cartagena, Colombia
- Colon, Panama
- Panama Canal Transit
- Panama City, Panama
Ports
Miami, Florida - Cozumel, Mexico - Harvest Caye, Belize - Coxen Hole, Roatan, Bay Islands, Honduras - George Town, Grand Cayman - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Panama City, Panama - View more ports
10 Night Panama Canal: Cartagena & Cozumel (Miami To Panama Canal)
2025 sail dates:
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
See Offers |
$1504* |
$1807* |
$2607* |
$2857* |
|
|
|
See Offers |
$1507* |
$1807* |
$2607* |
$2857* |
|
|
|
$1504* |
$1807* |
$2607* |
$2857* |
||
|
|
See Offers |
$1507* |
$1807* |
$2607* |
$2857* |
|
|
|
See Offers |
$1507* |
$1807* |
$2607* |
$2857* |
|
|
|
See Offers |
$1504* |
$1807* |
$2607* |
$2857* |
|
|
See Offers |
$1507* |
$1807* |
$2607* |
$2857* |
|
|
|
See Offers |
$1504* |
$1807* |
$2607* |
$2857* |
Ports
- Miami, Florida
- Oranjestad, Aruba
- Kralendijk, Bonaire
- Willemstad, Curacao
- Cartagena, Colombia
- Panama Canal Transit
- Fuerte Amador, Panama
Ports
Miami, Florida - Oranjestad, Aruba - Kralendijk, Bonaire - Willemstad, Curacao - Cartagena, Colombia - Panama Canal Transit - Fuerte Amador, Panama - View more ports
Ports
- Miami, Florida
- Costa Maya (Mahahual), Mexico
- Harvest Caye, Belize
- Santo Tomas De Castilla, Guatemala
- Coxen Hole, Roatan, Bay Islands, Honduras
- Puerto Limon, Costa Rica
- Colon, Panama
- Cartagena, Colombia
Ports
Miami, Florida - Costa Maya (Mahahual), Mexico - Harvest Caye, Belize - Santo Tomas De Castilla, Guatemala - Coxen Hole, Roatan, Bay Islands, Honduras - Puerto Limon, Costa Rica - Colon, Panama - Cartagena, Colombia - View more ports
Ports
- Miami, Florida
- Costa Maya (Mahahual), Mexico
- Harvest Caye, Belize
- Coxen Hole, Roatan, Bay Islands, Honduras
- Puerto Limon, Costa Rica
- Panama Canal Transit
- Panama City, Panama
- Manta, Ecuador
- Salaverry (Trujillo), Peru
- Callao (Lima), Peru
- Pisco, Peru
- Coquimbo (La Serena), Chile
- San Antonio, Chile
- Puerto Montt, Chile
- Puerto Chacabuco, Chile
- Laguna San Rafael, Chile
- Cruise Chilean Fjords
- Punta Arenas, Chile
- Ushuaia, Tierra Del Fuego, Argentina
- Cruise Drake Passage
- Half Moon Island, Antarctica
- Cruise Paradise Harbor, Antarctica
- CRUISE ADMIRALTY BAY, ANTARCTICA
- Port Stanley, Falkland Islands
- Punta Del Este, Uruguay
- Buenos Aires, Argentina
Ports
Miami, Florida - Costa Maya (Mahahual), Mexico - Harvest Caye, Belize - Coxen Hole, Roatan, Bay Islands, Honduras - Puerto Limon, Costa Rica - Panama Canal Transit - Panama City, Panama - Manta, Ecuador - Salaverry (Trujillo), Peru - Callao (Lima), Peru - Pisco, Peru - Coquimbo (La Serena), Chile - San Antonio, Chile - Puerto Montt, Chile - Puerto Chacabuco, Chile - Laguna San Rafael, Chile - Cruise Chilean Fjords - Punta Arenas, Chile - Ushuaia, Tierra Del Fuego, Argentina - Cruise Drake Passage - Half Moon Island, Antarctica - Cruise Paradise Harbor, Antarctica - CRUISE ADMIRALTY BAY, ANTARCTICA - Port Stanley, Falkland Islands - Punta Del Este, Uruguay - Buenos Aires, Argentina - View more ports
Ports
- Miami, Florida
- Costa Maya (Mahahual), Mexico
- Harvest Caye, Belize
- Coxen Hole, Roatan, Bay Islands, Honduras
- Puerto Limon, Costa Rica
- Panama City, Panama
- Panama Canal Transit
- Manta, Ecuador
- Salaverry (Trujillo), Peru
- Callao (Lima), Peru
Ports
Miami, Florida - Costa Maya (Mahahual), Mexico - Harvest Caye, Belize - Coxen Hole, Roatan, Bay Islands, Honduras - Puerto Limon, Costa Rica - Panama City, Panama - Panama Canal Transit - Manta, Ecuador - Salaverry (Trujillo), Peru - Callao (Lima), Peru - View more ports
Ports
- Miami, Florida
- George Town, Grand Cayman
- Cartagena, Colombia
- Panama Canal Transit
- Puntarenas, Costa Rica
- Puerto Corinto, Nicaragua
- Puerto Quetzal, Guatemala
- Acapulco, Mexico
- Cabo San Lucas, Mexico
- Ensenada, Mexico
- San Pedro (Los Angeles), California
Ports
Miami, Florida - George Town, Grand Cayman - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Corinto, Nicaragua - Puerto Quetzal, Guatemala - Acapulco, Mexico - Cabo San Lucas, Mexico - Ensenada, Mexico - San Pedro (Los Angeles), California - View more ports
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
See Offers |
N/A |
N/A |
N/A |
$10499* |
|
|
|
N/A |
N/A |
N/A |
$10499* |
Ports
- Miami, Florida
- Cartagena, Colombia
- Panama Canal Transit
- Puntarenas, Costa Rica
- Cabo San Lucas, Mexico
- Seattle, Washington
Ports
Miami, Florida - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Cabo San Lucas, Mexico - Seattle, Washington - View more ports
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
See Offers |
$1458* |
N/A |
N/A |
$5539* |
|
|
|
$1458* |
N/A |
N/A |
$5539* |
||
|
|
See Offers |
$1458* |
N/A |
N/A |
$5539* |
|
|
$1451* |
$1821* |
$2141* |
$5532* |
||
|
|
See Offers |
$1458* |
N/A |
N/A |
$5539* |
Ports
- Miami, Florida
- Cozumel, Mexico
- Costa Maya (Mahahual), Mexico
- Harvest Caye, Belize
- Santo Tomas De Castilla, Guatemala
- Coxen Hole, Roatan, Bay Islands, Honduras
- Puerto Limon, Costa Rica
- Panama Canal Transit
- Panama City, Panama
- Cartagena, Colombia
- Santa Marta, Colombia
- Oranjestad, Aruba
- Willemstad, Curacao
- Kralendijk, Bonaire
- Port Antonio, Jamaica
- Nassau, Bahamas
Ports
Miami, Florida - Cozumel, Mexico - Costa Maya (Mahahual), Mexico - Harvest Caye, Belize - Santo Tomas De Castilla, Guatemala - Coxen Hole, Roatan, Bay Islands, Honduras - Puerto Limon, Costa Rica - Panama Canal Transit - Panama City, Panama - Cartagena, Colombia - Santa Marta, Colombia - Oranjestad, Aruba - Willemstad, Curacao - Kralendijk, Bonaire - Port Antonio, Jamaica - Nassau, Bahamas - View more ports
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
$5899* |
$6499* |
$9199* |
$10799* |
||
|
|
$5670* |
N/A |
N/A |
N/A |
||
|
|
See Offers |
$5670* |
N/A |
N/A |
N/A |
|
|
|
See Offers |
$6299* |
N/A |
N/A |
N/A |
|
|
|
$6299* |
N/A |
N/A |
N/A |
||
|
|
See Offers |
$5670* |
N/A |
N/A |
N/A |
|
|
|
See Offers |
$5670* |
N/A |
N/A |
N/A |
Ports
- Miami, Florida
- Cozumel, Mexico
- Costa Maya (Mahahual), Mexico
- Harvest Caye, Belize
- Santo Tomas De Castilla, Guatemala
- Coxen Hole, Roatan, Bay Islands, Honduras
- Puerto Limon, Costa Rica
- Panama City, Panama
- Panama Canal Transit
Ports
Miami, Florida - Cozumel, Mexico - Costa Maya (Mahahual), Mexico - Harvest Caye, Belize - Santo Tomas De Castilla, Guatemala - Coxen Hole, Roatan, Bay Islands, Honduras - Puerto Limon, Costa Rica - Panama City, Panama - Panama Canal Transit - View more ports
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
$3599* |
$3849* |
$5199* |
$5999* |
||
|
|
$2800* |
$3000* |
N/A |
N/A |
||
|
|
See Offers |
$2800* |
$3000* |
N/A |
N/A |
|
|
|
See Offers |
$3499* |
$3749* |
N/A |
N/A |
|
|
|
$3499* |
$3749* |
N/A |
N/A |
||
|
|
See Offers |
$2800* |
$3000* |
N/A |
N/A |
|
|
|
See Offers |
$2800* |
$3000* |
N/A |
N/A |
Ports
- Miami, Florida
- Cozumel, Mexico
- Costa Maya (Mahahual), Mexico
- Santo Tomas De Castilla, Guatemala
- Harvest Caye, Belize
- Coxen Hole, Roatan, Bay Islands, Honduras
- Puerto Limon, Costa Rica
- Panama Canal Transit
- Panama City, Panama
Ports
Miami, Florida - Cozumel, Mexico - Costa Maya (Mahahual), Mexico - Santo Tomas De Castilla, Guatemala - Harvest Caye, Belize - Coxen Hole, Roatan, Bay Islands, Honduras - Puerto Limon, Costa Rica - Panama Canal Transit - Panama City, Panama - View more ports
All prices are per person based on double occupancy and do not include port/government fees and gratuities.