1. Home
  2. Find a cruise
  3. Santos (Sao Paulo), Brazil cruises

Santos (Sao Paulo), Brazil cruises 50 Santos (Sao Paulo), Brazil cruises

Your search Clear selections

Any Destination
All Sail Months
Any Length
Santos (Sao Paulo), Brazil
Any Cruise Line
Any Ship

Close

50 cruises found

Filters Save search

Sort by

Filter by

More
Save search

Ports

  • Santos (Sao Paulo), Brazil
  • Buzios, Brazil
  • Salvador De Bahia, Brazil
  • Maceio, Brazil
View more ports

Ports

Santos (Sao Paulo), Brazil - Buzios, Brazil - Salvador De Bahia, Brazil - Maceio, Brazil - View more ports

MSC Grandiosa M

4.0
(71 Reviews)

2024 sail dates: Dec 07,

2025 sail dates: Jan 04, Feb 08, Feb 15, Feb 22, Mar 01, Mar 08, Mar 15, Mar 22, Mar 29, More

$735*
$105/night*
Inside
View Deal
$735* msccruisesusa.com $735* cheapcruises.com $728* cruisehub.com $735* dreamvacations.com $736* gotosea.com $735* cruises.com $736* americandiscountcruises.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 71 MSC Grandiosa reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

$823*

$915*

$1071*

$1723*

 

$823*

$915*

$1071*

$1723*

 

$816*

$908*

$1064*

$1716*

 

$823*

$915*

$1071*

$1723*

See Offers

$824*

$916*

$1072*

$1724*

 

$823*

$915*

$1071*

$1723*

See Offers

$824*

$916*

$1072*

$1724*

 

N/A

N/A

N/A

$1668*

 

N/A

N/A

N/A

$1669*

 

N/A

N/A

N/A

$1662*

 

N/A

N/A

N/A

$1669*

See Offers

N/A

N/A

N/A

$1669*

 

N/A

N/A

N/A

$1669*

See Offers

N/A

N/A

N/A

$1669*

 

$1098*

$1256*

$1434*

$2096*

 

$1098*

$1256*

$1434*

$2096*

 

$1091*

$1249*

$1427*

$2089*

 

$1098*

$1256*

$1434*

$2096*

See Offers

$1099*

$1257*

$1435*

$2097*

 

$1098*

$1256*

$1434*

$2096*

See Offers

$1099*

$1257*

$1435*

$2097*

 

N/A

N/A

N/A

$2369*

 

N/A

N/A

N/A

$2369*

 

N/A

N/A

N/A

$2362*

 

N/A

N/A

N/A

$2369*

See Offers

N/A

N/A

N/A

$2370*

See Offers

N/A

N/A

N/A

$2369*

See Offers

N/A

N/A

N/A

$2370*

 

N/A

N/A

N/A

$2369*

 

N/A

N/A

N/A

$2369*

 

N/A

N/A

N/A

$2362*

 

N/A

N/A

N/A

$2369*

See Offers

N/A

N/A

N/A

$2370*

 

N/A

N/A

N/A

$2369*

See Offers

N/A

N/A

N/A

$2370*

 

N/A

N/A

N/A

$2258*

 

N/A

N/A

N/A

$2258*

 

N/A

N/A

N/A

$2251*

 

N/A

N/A

N/A

$2258*

See Offers

N/A

N/A

N/A

$2259*

 

N/A

N/A

N/A

$2258*

See Offers

N/A

N/A

N/A

$2259*

 

$735*

$893*

$1061*

$1775*

 

$735*

$893*

$1061*

$1775*

 

$728*

$886*

$1054*

$1768*

 

$735*

$893*

$1061*

$1775*

See Offers

$736*

$894*

$1062*

$1776*

 

$735*

$893*

$1061*

$1775*

See Offers

$736*

$894*

$1062*

$1776*

 

$735*

$893*

$1061*

$1775*

 

$735*

$893*

$1061*

$1775*

 

$728*

$886*

$1054*

$1768*

 

$735*

$893*

$1061*

$1775*

See Offers

$736*

$894*

$1062*

$1776*

 

$735*

$893*

$1061*

$1775*

See Offers

$736*

$894*

$1062*

$1776*

 

$735*

$893*

$1061*

$1775*

 

$735*

$893*

$1061*

$1775*

 

$728*

$886*

$1054*

$1768*

 

$735*

$893*

$1061*

$1775*

See Offers

$736*

$894*

$1062*

$1776*

 

$735*

$893*

$1061*

$1775*

See Offers

$736*

$894*

$1062*

$1776*

 

$735*

$893*

$1061*

$1775*

 

$735*

$893*

$1061*

$1775*

 

$728*

$886*

$1054*

$1768*

 

$735*

$893*

$1061*

$1775*

See Offers

$736*

$894*

$1062*

$1776*

 

$735*

$893*

$1061*

$1775*

See Offers

$736*

$894*

$1062*

$1776*

 

$935*

$1082*

$1250*

$1964*

 

$935*

$1082*

$1250*

$1964*

 

$928*

$1075*

$1243*

$1957*

 

$935*

$1082*

$1250*

$1964*

See Offers

$936*

$1083*

$1251*

$1965*

See Offers

$935*

$1082*

$1250*

$1964*

See Offers

$936*

$1083*

$1251*

$1965*

 

$735*

$893*

$1061*

$1775*

 

$735*

$893*

$1061*

$1775*

 

$728*

$886*

$1054*

$1768*

 

$735*

$893*

$1061*

$1775*

See Offers

$736*

$894*

$1062*

$1776*

 

$735*

$893*

$1061*

$1775*

See Offers

$736*

$894*

$1062*

$1776*

 

$735*

$893*

$1061*

$1775*

 

$735*

$893*

$1061*

$1775*

 

$728*

$886*

$1054*

$1768*

 

$735*

$893*

$1061*

$1775*

See Offers

$736*

$894*

$1062*

$1776*

See Offers

$735*

$893*

$1061*

$1775*

See Offers

$736*

$894*

$1062*

$1776*

 

$735*

$893*

$1061*

$1775*

 

$735*

$893*

$1061*

$1775*

 

$728*

$886*

$1054*

$1768*

 

$735*

$893*

$1061*

$1775*

See Offers

$736*

$894*

$1062*

$1776*

 

$735*

$893*

$1061*

$1775*

See Offers

$736*

$894*

$1062*

$1776*

 

$788*

$960*

$1144*

$1922*

 

$788*

$960*

$1144*

$1922*

 

$781*

$953*

$1137*

$1915*

 

$788*

$960*

$1144*

$1922*

See Offers

$789*

$961*

$1145*

$1923*

See Offers

$788*

$960*

$1144*

$1922*

See Offers

$789*

$961*

$1145*

$1923*

Ports

  • Buenos Aires, Argentina
  • Punta Del Este, Uruguay
  • CAMBORIU, BRAZIL
  • Santos (Sao Paulo), Brazil
View more ports

Ports

Buenos Aires, Argentina - Punta Del Este, Uruguay - CAMBORIU, BRAZIL - Santos (Sao Paulo), Brazil - View more ports

MSC Splendida XL

3.5
(112 Reviews)

2024 sail dates:

2025 sail dates: Jan 13,

$1391*
$199/night*
Inside
View Deal
$1391* msccruisesusa.com $1391* cheapcruises.com $1384* cruisehub.com $1391* dreamvacations.com $1392* gotosea.com $1391* cruises.com $1392* americandiscountcruises.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 112 MSC Splendida reviews

Ports

  • Santos (Sao Paulo), Brazil
  • Rio De Janeiro, Brazil
  • Buzios, Brazil
  • Salvador De Bahia, Brazil
  • Maceio, Brazil
  • Las Palmas, Gran Canaria, Canary Islands
  • Arrecife, Lanzarote, Canary Islands
  • Tangier, Morocco
  • Malaga, Spain
  • Valencia, Spain
  • Marseille (Provence), France
  • GENOA (PORTOFINO), ITALY
  • Civitavecchia (Rome), Italy
View more ports

Ports

Santos (Sao Paulo), Brazil - Rio De Janeiro, Brazil - Buzios, Brazil - Salvador De Bahia, Brazil - Maceio, Brazil - Las Palmas, Gran Canaria, Canary Islands - Arrecife, Lanzarote, Canary Islands - Tangier, Morocco - Malaga, Spain - Valencia, Spain - Marseille (Provence), France - GENOA (PORTOFINO), ITALY - Civitavecchia (Rome), Italy - View more ports

MSC Grandiosa M

4.0
(71 Reviews)

2025 sail dates:

$1548*
$70/night*
Inside
View Deal
$1548* msccruisesusa.com $1548* cheapcruises.com $1541* cruisehub.com $1548* dreamvacations.com $1549* gotosea.com $1548* cruises.com $1549* americandiscountcruises.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 71 MSC Grandiosa reviews

Ports

  • Santos (Sao Paulo), Brazil
  • Rio De Janeiro, Brazil
  • Buzios, Brazil
  • Salvador De Bahia, Brazil
  • Maceio, Brazil
  • Las Palmas, Gran Canaria, Canary Islands
  • Arrecife, Lanzarote, Canary Islands
  • Tangier, Morocco
  • Malaga, Spain
  • Valencia, Spain
View more ports

Ports

Santos (Sao Paulo), Brazil - Rio De Janeiro, Brazil - Buzios, Brazil - Salvador De Bahia, Brazil - Maceio, Brazil - Las Palmas, Gran Canaria, Canary Islands - Arrecife, Lanzarote, Canary Islands - Tangier, Morocco - Malaga, Spain - Valencia, Spain - View more ports

MSC Grandiosa M

4.0
(71 Reviews)

2025 sail dates:

$1109*
$58/night*
Inside
View Deal
$1109* msccruisesusa.com $1108* cheapcruises.com $1102* cruisehub.com $1108* dreamvacations.com $1109* gotosea.com $1108* cruises.com $1109* americandiscountcruises.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 71 MSC Grandiosa reviews

Ports

  • Santos (Sao Paulo), Brazil
  • Rio De Janeiro, Brazil
  • Buzios, Brazil
  • Salvador De Bahia, Brazil
  • Maceio, Brazil
  • Las Palmas, Gran Canaria, Canary Islands
  • Arrecife, Lanzarote, Canary Islands
  • Tangier, Morocco
  • Malaga, Spain
  • Valencia, Spain
  • Marseille (Provence), France
  • GENOA (PORTOFINO), ITALY
View more ports

Ports

Santos (Sao Paulo), Brazil - Rio De Janeiro, Brazil - Buzios, Brazil - Salvador De Bahia, Brazil - Maceio, Brazil - Las Palmas, Gran Canaria, Canary Islands - Arrecife, Lanzarote, Canary Islands - Tangier, Morocco - Malaga, Spain - Valencia, Spain - Marseille (Provence), France - GENOA (PORTOFINO), ITALY - View more ports

MSC Grandiosa M

4.0
(71 Reviews)

2025 sail dates:

$1290*
$61/night*
Inside
View Deal
$1290* msccruisesusa.com $1287* cheapcruises.com $1283* cruisehub.com $1287* dreamvacations.com $1291* gotosea.com $1287* cruises.com $1291* americandiscountcruises.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 71 MSC Grandiosa reviews

Ports

  • Santos (Sao Paulo), Brazil
  • Rio De Janeiro, Brazil
  • Buzios, Brazil
  • Salvador De Bahia, Brazil
  • Maceio, Brazil
  • Las Palmas, Gran Canaria, Canary Islands
  • Arrecife, Lanzarote, Canary Islands
  • Tangier, Morocco
  • Malaga, Spain
View more ports

Ports

Santos (Sao Paulo), Brazil - Rio De Janeiro, Brazil - Buzios, Brazil - Salvador De Bahia, Brazil - Maceio, Brazil - Las Palmas, Gran Canaria, Canary Islands - Arrecife, Lanzarote, Canary Islands - Tangier, Morocco - Malaga, Spain - View more ports

MSC Grandiosa M

4.0
(71 Reviews)

2025 sail dates:

$987*
$58/night*
Inside
View Deal
$987* cheapcruises.com $987* dreamvacations.com $987* cruises.com $994* americandiscountcruises.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 71 MSC Grandiosa reviews

Ports

  • Buenos Aires, Argentina
  • CAMBORIU, BRAZIL
  • Sao Francisco Do Sul, Brazil
  • Santos (Sao Paulo), Brazil
  • Ilhabela, Brazil
  • Angras Dos Reis, Brazil
  • Rio De Janeiro, Brazil
View more ports

Ports

Buenos Aires, Argentina - CAMBORIU, BRAZIL - Sao Francisco Do Sul, Brazil - Santos (Sao Paulo), Brazil - Ilhabela, Brazil - Angras Dos Reis, Brazil - Rio De Janeiro, Brazil - View more ports

Crystal Serenity XL

4.4
(104 Reviews)

2025 sail dates:

$6600*
$600/night*
Oceanview
View Deal
$6600* luxurycruiseconnections.com $6600* gotosea.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 104 Crystal Serenity reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

$6600*

N/A

N/A

See Offers

N/A

$6600*

N/A

N/A

Ports

  • Buenos Aires, Argentina
  • Montevideo, Uruguay
  • Punta Del Este, Uruguay
  • Itajai, Brazil
  • Santos (Sao Paulo), Brazil
  • Ilha Grande, Brazil
  • Buzios, Brazil
  • Rio De Janeiro, Brazil
View more ports

Ports

Buenos Aires, Argentina - Montevideo, Uruguay - Punta Del Este, Uruguay - Itajai, Brazil - Santos (Sao Paulo), Brazil - Ilha Grande, Brazil - Buzios, Brazil - Rio De Janeiro, Brazil - View more ports

Seven Seas Splendor M

4.4
(40 Reviews)

2025 sail dates:

$9299*
$930/night*
Suite
View Deal
$9299* luxurycruiseconnections.com $9299* avoyatravel.com $7699* luxuryonly.com $7699* dreamvacations.com $9299* gotosea.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 40 Seven Seas Splendor reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$9299*

See Offers

$25999*

N/A

N/A

$9299*

 

N/A

N/A

N/A

$7699*

 

N/A

N/A

N/A

$7699*

See Offers

N/A

N/A

N/A

$9299*

Ports

  • Buenos Aires, Argentina
  • Montevideo, Uruguay
  • Punta Del Este, Uruguay
  • Itajai, Brazil
  • Santos (Sao Paulo), Brazil
  • Ilha Grande, Brazil
  • Buzios, Brazil
  • Rio De Janeiro, Brazil
  • Salvador De Bahia, Brazil
  • Maceio, Brazil
  • Recife, Brazil
  • Sao Vicente, Cape Verde Islands
  • Santa Cruz De Tenerife, Canary Islands
  • Arrecife, Lanzarote, Canary Islands
  • Lisbon, Portugal
View more ports

Ports

Buenos Aires, Argentina - Montevideo, Uruguay - Punta Del Este, Uruguay - Itajai, Brazil - Santos (Sao Paulo), Brazil - Ilha Grande, Brazil - Buzios, Brazil - Rio De Janeiro, Brazil - Salvador De Bahia, Brazil - Maceio, Brazil - Recife, Brazil - Sao Vicente, Cape Verde Islands - Santa Cruz De Tenerife, Canary Islands - Arrecife, Lanzarote, Canary Islands - Lisbon, Portugal - View more ports

Seven Seas Splendor M

4.4
(40 Reviews)

2025 sail dates:

$14099*
$542/night*
Suite
View Deal
$14099* luxurycruiseconnections.com $14099* avoyatravel.com $14099* luxuryonly.com $14099* dreamvacations.com $14099* gotosea.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 40 Seven Seas Splendor reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$14099*

See Offers

N/A

N/A

N/A

$14099*

 

N/A

N/A

N/A

$14099*

 

N/A

N/A

N/A

$14099*

See Offers

N/A

N/A

N/A

$14099*

Ports

  • San Antonio, Chile
  • Puerto Montt, Chile
  • Puerto Chacabuco, Chile
  • Laguna San Rafael, Chile
  • Cruise Chilean Fjords
  • Punta Arenas, Chile
  • Cruise Cape Horn
  • Ushuaia, Tierra Del Fuego, Argentina
  • Port Stanley, Falkland Islands
  • Puerto Madryn, Argentina
  • Punta Del Este, Uruguay
  • Montevideo, Uruguay
  • Buenos Aires, Argentina
  • Itajai, Brazil
  • Sao Francisco Do Sul, Brazil
  • Santos (Sao Paulo), Brazil
  • Parati, Brazil
  • Ilha Grande, Brazil
  • Buzios, Brazil
  • Rio De Janeiro, Brazil
  • Salvador De Bahia, Brazil
  • Maceio, Brazil
  • Recife, Brazil
  • Porto Grande, Cape Verde Islands
  • Dakar, Senegal
  • San Sebastian De La Gomera, Canary Islands
  • Santa Cruz De Tenerife, Canary Islands
  • Santa Cruz De La Palma, Canary Islands
  • Funchal, Madeira
  • Casablanca, Morocco
  • Gibraltar (U.K.)
  • Almeria, Spain
  • Malaga, Spain
  • Cadiz (Seville), Spain
  • Lisbon, Portugal
  • Huelva, Spain
  • Tangier, Morocco
  • Melilla, Spainsh Morocco
  • Alicante, Spain
  • Palma De Mallorca, Balearic Islands
  • Marseille (Provence), France
  • Barcelona, Spain
View more ports

Ports

San Antonio, Chile - Puerto Montt, Chile - Puerto Chacabuco, Chile - Laguna San Rafael, Chile - Cruise Chilean Fjords - Punta Arenas, Chile - Cruise Cape Horn - Ushuaia, Tierra Del Fuego, Argentina - Port Stanley, Falkland Islands - Puerto Madryn, Argentina - Punta Del Este, Uruguay - Montevideo, Uruguay - Buenos Aires, Argentina - Itajai, Brazil - Sao Francisco Do Sul, Brazil - Santos (Sao Paulo), Brazil - Parati, Brazil - Ilha Grande, Brazil - Buzios, Brazil - Rio De Janeiro, Brazil - Salvador De Bahia, Brazil - Maceio, Brazil - Recife, Brazil - Porto Grande, Cape Verde Islands - Dakar, Senegal - San Sebastian De La Gomera, Canary Islands - Santa Cruz De Tenerife, Canary Islands - Santa Cruz De La Palma, Canary Islands - Funchal, Madeira - Casablanca, Morocco - Gibraltar (U.K.) - Almeria, Spain - Malaga, Spain - Cadiz (Seville), Spain - Lisbon, Portugal - Huelva, Spain - Tangier, Morocco - Melilla, Spainsh Morocco - Alicante, Spain - Palma De Mallorca, Balearic Islands - Marseille (Provence), France - Barcelona, Spain - View more ports

Marina M

4.2
(214 Reviews)

2025 sail dates:

$19799*
$314/night*
Inside
View Deal
$19799* oceaniacruises.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 214 Marina reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

$19799*

$23349*

$25899*

$34299*

 

N/A

N/A

$22899*

N/A

See Offers

N/A

N/A

$22899*

N/A

See Offers

N/A

N/A

$22899*

N/A

1 - 10 of 50

All prices are per person based on double occupancy and do not include port/government fees and gratuities.