Colon, Panama cruises 234 Colon, Panama cruises

Your search Clear selections

Any Destination
All Sail Months
Any Length
Colon, Panama
Any Cruise Line
Any Ship

Close

234 cruises found

Sort by

Filter by

More

Ports

  • Galveston, Texas
  • Cozumel, Mexico
  • Harvest Caye, Belize
  • Coxen Hole, Roatan, Bay Islands, Honduras
  • George Town, Grand Cayman
  • Cartagena, Colombia
  • Colon, Panama
  • Panama Canal Transit
  • Panama City, Panama
View more ports

Ports

Galveston, Texas - Cozumel, Mexico - Harvest Caye, Belize - Coxen Hole, Roatan, Bay Islands, Honduras - George Town, Grand Cayman - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Panama City, Panama - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Ports

  • Ft. Lauderdale (Port Everglades), Florida
  • Cozumel, Mexico
  • Cartagena, Colombia
  • Colon, Panama
  • Panama Canal Transit
  • Puntarenas, Costa Rica
  • Cabo San Lucas, Mexico
  • San Pedro (Los Angeles), California
  • Honolulu, Oahu
  • Nawiliwili, Kauai
  • VAITAPE, BORA BORA, FRENCH POLYNESIA
  • Moorea, French Polynesia
  • Papeete, Tahiti
  • AVATIU, COOK ISLANDS
  • Cross International Dateline
  • Waitangi, Bay Of Islands, New Zealand
  • Auckland, New Zealand
  • Tauranga, New Zealand
  • Napier, New Zealand
  • Wellington, New Zealand
  • Sydney, Australia
  • Brisbane, Australia
  • Whitsunday Islands, Australia
  • Cairns, Australia
  • Thursday Island, Australia
  • Darwin, Australia
  • KOMODO NATIONAL PARK, INDONESIA
  • Benoa, Bali, Indonesia
  • Semarang, Java, Indonesia
  • Tanjung Priok (Jakarta), Indonesia
  • Singapore
  • Cruise Strait Of Malacca
  • Port Klang (Kuala Lumpur), Malaysia
  • Langkawi (Pulau Langkawi), Malaysia
  • GEORGE TOWN, PENANG, MALAYSIA
  • Phuket, Thailand
  • Colombo, Sri Lanka
  • Male, Maldives
  • Victoria, Mahe, Seychelles
  • Mombasa, Kenya
  • Zanzibar, Tanzania
  • ANDOANY (HELL-VILLE), NOSY-BE, MADAGASCAR
  • Maputo, Mozambique
  • Richards Bay, South Africa
  • Durban, South Africa
  • East London, South Africa
  • Port Elizabeth, South Africa
  • Cape Town, South Africa
  • Luderitz, Namibia
  • Walvis Bay, Namibia
  • Luanda, Angola
  • Praia, Santiago, Cape Verde
  • Mindelo, Cape Verde Island
  • Santa Cruz De Tenerife, Canary Islands
  • Agadir, Morocco
  • Casablanca, Morocco
  • Cadiz (Seville), Spain
  • Lisbon, Portugal
  • Leixoes (Oporto), Portugal
  • La Coruna, Spain
  • Honfleur, France
  • Dover (London), England
  • Greenwich (London), England
View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Cozumel, Mexico - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Puntarenas, Costa Rica - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - Honolulu, Oahu - Nawiliwili, Kauai - VAITAPE, BORA BORA, FRENCH POLYNESIA - Moorea, French Polynesia - Papeete, Tahiti - AVATIU, COOK ISLANDS - Cross International Dateline - Waitangi, Bay Of Islands, New Zealand - Auckland, New Zealand - Tauranga, New Zealand - Napier, New Zealand - Wellington, New Zealand - Sydney, Australia - Brisbane, Australia - Whitsunday Islands, Australia - Cairns, Australia - Thursday Island, Australia - Darwin, Australia - KOMODO NATIONAL PARK, INDONESIA - Benoa, Bali, Indonesia - Semarang, Java, Indonesia - Tanjung Priok (Jakarta), Indonesia - Singapore - Cruise Strait Of Malacca - Port Klang (Kuala Lumpur), Malaysia - Langkawi (Pulau Langkawi), Malaysia - GEORGE TOWN, PENANG, MALAYSIA - Phuket, Thailand - Colombo, Sri Lanka - Male, Maldives - Victoria, Mahe, Seychelles - Mombasa, Kenya - Zanzibar, Tanzania - ANDOANY (HELL-VILLE), NOSY-BE, MADAGASCAR - Maputo, Mozambique - Richards Bay, South Africa - Durban, South Africa - East London, South Africa - Port Elizabeth, South Africa - Cape Town, South Africa - Luderitz, Namibia - Walvis Bay, Namibia - Luanda, Angola - Praia, Santiago, Cape Verde - Mindelo, Cape Verde Island - Santa Cruz De Tenerife, Canary Islands - Agadir, Morocco - Casablanca, Morocco - Cadiz (Seville), Spain - Lisbon, Portugal - Leixoes (Oporto), Portugal - La Coruna, Spain - Honfleur, France - Dover (London), England - Greenwich (London), England - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$85995*

N/A

 

N/A

N/A

$85995*

N/A

See Offers

N/A

N/A

$85995*

N/A

 

N/A

N/A

$85995*

N/A

 

N/A

N/A

$59995*

$119995*

 

N/A

N/A

$59995*

N/A

See Offers

N/A

N/A

$59995*

$119995*

 

N/A

N/A

$59995*

N/A

Ports

  • Ft. Lauderdale (Port Everglades), Florida
  • Cozumel, Mexico
  • Cartagena, Colombia
  • Colon, Panama
  • Panama Canal Transit
  • Puerto Caldera, Costa Rica
  • Cabo San Lucas, Mexico
  • San Pedro (Los Angeles), California
View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Cozumel, Mexico - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Puerto Caldera, Costa Rica - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$5999*

N/A

 

N/A

N/A

$5999*

N/A

See Offers

N/A

N/A

$5999*

N/A

 

N/A

N/A

$5999*

N/A

Ports

  • Ft. Lauderdale (Port Everglades), Florida
  • Cozumel, Mexico
  • Cartagena, Colombia
  • Colon, Panama
  • Panama Canal Transit
  • Puntarenas, Costa Rica
  • Cabo San Lucas, Mexico
  • San Pedro (Los Angeles), California
  • Honolulu, Oahu
  • Nawiliwili, Kauai
  • VAITAPE, BORA BORA, FRENCH POLYNESIA
  • Papeete, Tahiti
  • Moorea, French Polynesia
  • AVATIU, COOK ISLANDS
  • Cross International Dateline
  • Waitangi, Bay Of Islands, New Zealand
  • Auckland, New Zealand
  • Tauranga, New Zealand
  • Napier, New Zealand
  • Wellington, New Zealand
  • Sydney, Australia
  • Brisbane, Australia
  • Whitsunday Islands, Australia
  • Cairns, Australia
  • Thursday Island, Australia
  • Darwin, Australia
  • KOMODO NATIONAL PARK, INDONESIA
  • Benoa, Bali, Indonesia
  • Semarang, Java, Indonesia
  • Tanjung Priok (Jakarta), Indonesia
  • Singapore
  • Cruise Strait Of Malacca
  • Port Klang (Kuala Lumpur), Malaysia
  • Langkawi (Pulau Langkawi), Malaysia
  • GEORGE TOWN, PENANG, MALAYSIA
  • Phuket, Thailand
  • Colombo, Sri Lanka
  • Male, Maldives
  • Victoria, Mahe, Seychelles
  • Mombasa, Kenya
  • Zanzibar, Tanzania
  • ANDOANY (HELL-VILLE), NOSY-BE, MADAGASCAR
  • Maputo, Mozambique
  • Richards Bay, South Africa
  • Durban, South Africa
  • East London, South Africa
  • Port Elizabeth, South Africa
  • Cape Town, South Africa
  • Luderitz, Namibia
  • Walvis Bay, Namibia
  • Luanda, Angola
  • Praia, Santiago, Cape Verde
  • Mindelo, Cape Verde Island
  • Santa Cruz De Tenerife, Canary Islands
  • Agadir, Morocco
  • Casablanca, Morocco
  • Cadiz (Seville), Spain
  • Lisbon, Portugal
  • Leixoes (Oporto), Portugal
  • La Coruna, Spain
  • Honfleur, France
  • Dover (London), England
  • Greenwich (London), England
  • Cruise English Channel
  • Dun Laoghaire (Dublin), Ireland
  • Holyhead, Wales
  • Liverpool, England
  • Belfast, Northern Ireland
  • Ullapool, Scotland
  • Kirkwall, Orkney Islands, Scotland
  • Leith (Edinburgh), Scotland
  • Invergordon (Inverness & Loch Ness), Scotland
  • Lerwick, Shetland Islands, Scotland
  • Bergen, Norway
  • Geiranger, Norway
  • Cruise Inside Passage, Norway
  • Narvik
  • Leknes, Norway
  • Tromso, Norway
  • Honningsvag, Norway
  • Longyearbyen, Spitzbergen, Norway
  • Isafjordur, Iceland
  • Reykjavik, Iceland
  • Heimaey, Westman Islands, Iceland
  • Djupivogur, Iceland
  • Seydisfjordur, Iceland
  • Akureyri, Iceland
  • Nanortalik, Greenland
  • Qaqortoq, Greenland
  • L'Anse Aux Meadows, Newfoundland
  • Halifax, Nova Scotia
  • New York, New York
View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Cozumel, Mexico - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Puntarenas, Costa Rica - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - Honolulu, Oahu - Nawiliwili, Kauai - VAITAPE, BORA BORA, FRENCH POLYNESIA - Papeete, Tahiti - Moorea, French Polynesia - AVATIU, COOK ISLANDS - Cross International Dateline - Waitangi, Bay Of Islands, New Zealand - Auckland, New Zealand - Tauranga, New Zealand - Napier, New Zealand - Wellington, New Zealand - Sydney, Australia - Brisbane, Australia - Whitsunday Islands, Australia - Cairns, Australia - Thursday Island, Australia - Darwin, Australia - KOMODO NATIONAL PARK, INDONESIA - Benoa, Bali, Indonesia - Semarang, Java, Indonesia - Tanjung Priok (Jakarta), Indonesia - Singapore - Cruise Strait Of Malacca - Port Klang (Kuala Lumpur), Malaysia - Langkawi (Pulau Langkawi), Malaysia - GEORGE TOWN, PENANG, MALAYSIA - Phuket, Thailand - Colombo, Sri Lanka - Male, Maldives - Victoria, Mahe, Seychelles - Mombasa, Kenya - Zanzibar, Tanzania - ANDOANY (HELL-VILLE), NOSY-BE, MADAGASCAR - Maputo, Mozambique - Richards Bay, South Africa - Durban, South Africa - East London, South Africa - Port Elizabeth, South Africa - Cape Town, South Africa - Luderitz, Namibia - Walvis Bay, Namibia - Luanda, Angola - Praia, Santiago, Cape Verde - Mindelo, Cape Verde Island - Santa Cruz De Tenerife, Canary Islands - Agadir, Morocco - Casablanca, Morocco - Cadiz (Seville), Spain - Lisbon, Portugal - Leixoes (Oporto), Portugal - La Coruna, Spain - Honfleur, France - Dover (London), England - Greenwich (London), England - Cruise English Channel - Dun Laoghaire (Dublin), Ireland - Holyhead, Wales - Liverpool, England - Belfast, Northern Ireland - Ullapool, Scotland - Kirkwall, Orkney Islands, Scotland - Leith (Edinburgh), Scotland - Invergordon (Inverness & Loch Ness), Scotland - Lerwick, Shetland Islands, Scotland - Bergen, Norway - Geiranger, Norway - Cruise Inside Passage, Norway - Narvik - Leknes, Norway - Tromso, Norway - Honningsvag, Norway - Longyearbyen, Spitzbergen, Norway - Isafjordur, Iceland - Reykjavik, Iceland - Heimaey, Westman Islands, Iceland - Djupivogur, Iceland - Seydisfjordur, Iceland - Akureyri, Iceland - Nanortalik, Greenland - Qaqortoq, Greenland - L'Anse Aux Meadows, Newfoundland - Halifax, Nova Scotia - New York, New York - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$135995*

Ports

  • Miami, Florida
  • Costa Maya (Mahahual), Mexico
  • Harvest Caye, Belize
  • Coxen Hole, Roatan, Bay Islands, Honduras
  • Puerto Limon, Costa Rica
  • Colon, Panama
  • Cartagena, Colombia
  • Willemstad, Curacao
  • Oranjestad, Aruba
  • Castries, St. Lucia
  • Bridgetown, Barbados
View more ports

Ports

Miami, Florida - Costa Maya (Mahahual), Mexico - Harvest Caye, Belize - Coxen Hole, Roatan, Bay Islands, Honduras - Puerto Limon, Costa Rica - Colon, Panama - Cartagena, Colombia - Willemstad, Curacao - Oranjestad, Aruba - Castries, St. Lucia - Bridgetown, Barbados - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Ports

  • Miami, Florida
  • Costa Maya (Mahahual), Mexico
  • Harvest Caye, Belize
  • Coxen Hole, Roatan, Bay Islands, Honduras
  • Puerto Limon, Costa Rica
  • Colon, Panama
  • Cartagena, Colombia
  • Willemstad, Curacao
  • Oranjestad, Aruba
  • Castries, St. Lucia
  • Bridgetown, Barbados
  • Scarborough, Tobago
  • Cruise Amazon River
  • Santarem, Brazil
  • Boca Da Valeria, Brazil
  • Manaus, Brazil
  • Parintins, Brazil
  • Alter Do Chao, Brazil
  • Devils Island, French Guiana
  • St. George's, Grenada
  • Terre-De-Haut, Iles Des Saintes, Guadeloupe
  • Rodney Bay, St. Lucia
View more ports

Ports

Miami, Florida - Costa Maya (Mahahual), Mexico - Harvest Caye, Belize - Coxen Hole, Roatan, Bay Islands, Honduras - Puerto Limon, Costa Rica - Colon, Panama - Cartagena, Colombia - Willemstad, Curacao - Oranjestad, Aruba - Castries, St. Lucia - Bridgetown, Barbados - Scarborough, Tobago - Cruise Amazon River - Santarem, Brazil - Boca Da Valeria, Brazil - Manaus, Brazil - Parintins, Brazil - Alter Do Chao, Brazil - Devils Island, French Guiana - St. George's, Grenada - Terre-De-Haut, Iles Des Saintes, Guadeloupe - Rodney Bay, St. Lucia - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

$9099*

$9799*

$13399*

$15499*

Ports

  • Ft. Lauderdale (Port Everglades), Florida
  • Cartagena, Colombia
  • Colon, Panama
  • Panama Canal (Cruise Into Canal)
  • Willemstad, Curacao
  • Oranjestad, Aruba
  • George Town, Grand Cayman
View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Willemstad, Curacao - Oranjestad, Aruba - George Town, Grand Cayman - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$9871*

 

N/A

N/A

N/A

$9761*

See Offers

N/A

N/A

N/A

$9871*

See Offers

N/A

N/A

N/A

$9871*

See Offers

N/A

N/A

N/A

$9761*

See Offers

N/A

N/A

N/A

$9762*

See Offers

N/A

N/A

N/A

$9871*

 

N/A

N/A

N/A

$9761*

Ports

  • Belize City, Belize
  • Santo Tomas De Castilla, Guatemala
  • Isla De Utila, Honduras
  • Coxen Hole, Roatan, Bay Islands, Honduras
  • CORN ISLANDS, NICARAGUA
  • Puerto Limon, Costa Rica
  • Bocas Del Toro, Panama
  • Colon, Panama
View more ports

Ports

Belize City, Belize - Santo Tomas De Castilla, Guatemala - Isla De Utila, Honduras - Coxen Hole, Roatan, Bay Islands, Honduras - CORN ISLANDS, NICARAGUA - Puerto Limon, Costa Rica - Bocas Del Toro, Panama - Colon, Panama - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$9030*

$17070*

 

N/A

N/A

$7870*

$12790*

 

N/A

N/A

$7870*

$12790*

Ports

  • Cartagena, Colombia
  • Colon, Panama
  • Coxen Hole, Roatan, Bay Islands, Honduras
  • Belize City, Belize
  • Cozumel, Mexico
  • Ft. Lauderdale (Port Everglades), Florida
View more ports

Ports

Cartagena, Colombia - Colon, Panama - Coxen Hole, Roatan, Bay Islands, Honduras - Belize City, Belize - Cozumel, Mexico - Ft. Lauderdale (Port Everglades), Florida - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$7000*

 

N/A

N/A

N/A

$7000*

See Offers

N/A

N/A

N/A

$7000*

 

N/A

N/A

N/A

$7000*

Ports

  • Colon, Panama
  • San Blas Islands, Panama
  • Panama Canal Transit
  • PLAYA MUERTO, DARIEN, PANAMA
  • Fuerte Amador, Panama
  • Puerto Quepos, Costa Rica
  • Puntarenas, Costa Rica
View more ports

Ports

Colon, Panama - San Blas Islands, Panama - Panama Canal Transit - PLAYA MUERTO, DARIEN, PANAMA - Fuerte Amador, Panama - Puerto Quepos, Costa Rica - Puntarenas, Costa Rica - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$18034*

 

N/A

N/A

$7374*

$12164*

 

N/A

N/A

$7374*

$12164*

All prices are per person based on double occupancy and do not include port/government fees and gratuities.