Colon, Panama cruises 228 Colon, Panama cruises

Your search Clear selections

Any Destination

All Sail Months

Any Length

Colon, Panama

Any Cruise Line

Any Ship

228 cruises found

Filters Save search

Ports

Baltimore, Maryland
CELEBRATION KEY, BAHAMAS
Ocho Rios, Jamaica
Puerto Limon, Costa Rica
Colon, Panama
Grand Turk Island

View more ports

Ports

Baltimore, Maryland - CELEBRATION KEY, BAHAMAS - Ocho Rios, Jamaica - Puerto Limon, Costa Rica - Colon, Panama - Grand Turk Island - View more ports

14 Night Carnival Journeys - Panama Canal (Baltimore Roundtrip)

Carnival Pride L

4.0

(3004 Reviews)

2026 sail dates: Jan 11

$1499*

$107/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 3004 Carnival Pride reviews

Compare Prices

Inside	Oceanview	Balcony	Suite
$1499*	$1649*	$2199*	N/A
$1499*	$1649*	$2199*	N/A
$1489*	$1639*	$2189*	N/A
$1499*	$1649*	$2199*	N/A
$1499*	$1649*	$2199*	N/A

Ports

Colon, Panama
Cartagena, Colombia
Kralendijk, Bonaire
Oranjestad, Aruba

View more ports

Ports

Colon, Panama - Cartagena, Colombia - Kralendijk, Bonaire - Oranjestad, Aruba - View more ports

7 Night Southern Caribbean (Colon Roundtrip)

Serenade of the Seas L

4.1

(1797 Reviews)

2026 sail dates: Jan 17

$701*

$100/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 1797 Serenade of the Seas reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$701*	$801*	$1003*	$1430*
See Offers	$702*	$802*	$1004*	$1431*
	$701*	$801*	$1003*	$1430*
	$701*	$801*	$1003*	$1430*
See Offers	$701*	$801*	$1004*	$1430*
	$696*	$796*	$998*	$1425*
See Offers	$701*	$801*	$1004*	$1430*
	$701*	$801*	$1003*	$1430*

Ports

Ft. Lauderdale (Port Everglades), Florida
Oranjestad, Aruba
Cartagena, Colombia
Panama Canal (Cruise Into Canal)
Colon, Panama
Puerto Limon, Costa Rica
Princess Cays (Cruise Line Private Island)

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Oranjestad, Aruba - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - Princess Cays (Cruise Line Private Island) - View more ports

12 Night Panama Canal With Costa Rica & Caribbean (Ft. Lauderdale Roundtrip)

Caribbean Princess L

3.9

(1889 Reviews)

2026 sail dates: Oct 30, Nov 23, Dec 05

2027 sail dates: Jan 10, Jan 22

$1099*

$92/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 1889 Caribbean Princess reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1149*	$1399*	$2099*	$4399*
	$1149*	$1259*	$2099*	$2949*
See Offers	$1149*	$1259*	$2099*	$2949*
	$1149*	$1259*	$2099*	$2949*
See Offers	$1149*	$1259*	$2099*	$2949*
	$1149*	$1259*	$2099*	$2949*
See Offers	$1149*	$1259*	$2099*	$2949*
	$1199*	$1449*	$2149*	$4499*
	$1199*	$1319*	$2149*	$2999*
See Offers	$1199*	$1319*	$2149*	$2999*
	$1199*	$1319*	$2149*	$2999*
	$1199*	$1319*	$2149*	$2999*
	$1199*	$1319*	$2149*	$2999*
See Offers	$1199*	$1319*	$2149*	$2999*
	$1099*	$1299*	$1949*	$4099*
	$1099*	$1199*	$1949*	$2749*
See Offers	$1099*	$1199*	$1949*	$2749*
	$1099*	$1199*	$1949*	$2749*
	$1099*	$1199*	$1949*	$2749*
	$1099*	$1199*	$1949*	$2749*
See Offers	$1099*	$1199*	$1949*	$2749*
	$1149*	$1399*	$2099*	$4399*
	$1149*	$1269*	$2099*	$2949*
See Offers	$1149*	$1269*	$2099*	$2949*
	$1149*	$1269*	$2099*	$2949*
See Offers	$1149*	$1269*	$2099*	$2949*
	$1149*	$1269*	$2099*	$2949*
See Offers	$1149*	$1269*	$2099*	$2949*
	$1149*	$1399*	$2099*	$4399*
	$1149*	$1259*	$2099*	$2949*
See Offers	$1149*	$1259*	$2099*	$2949*
	$1149*	$1259*	$2099*	$2949*
	$1149*	$1259*	$2099*	$2949*
	$1149*	$1259*	$2099*	$2949*
See Offers	$1149*	$1259*	$2099*	$2949*

Ports

Miami, Florida
Cartagena, Colombia
Colon, Panama
Panama Canal Transit
Puntarenas, Costa Rica
Puerto Quetzal, Guatemala
Acapulco, Mexico
Cabo San Lucas, Mexico
San Diego, California

View more ports

Ports

Miami, Florida - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Acapulco, Mexico - Cabo San Lucas, Mexico - San Diego, California - View more ports

15 Night Panama Canal: Mexico & Costa Rica (Miami To San Diego)

Norwegian Star L

3.6

(2053 Reviews)

2026 sail dates: Dec 04

$1918*

$128/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 2053 Norwegian Star reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1918*	$2368*	$3218*	$4468*
See Offers	$1918*	$2368*	$3218*	$3868*
See Offers	$1868*	$2318*	$3168*	$3818*
	$1918*	$2368*	$3218*	$3868*
	$1918*	$2368*	$3218*	$3868*
	$1918*	$2368*	$3218*	$3868*
	$1918*	$2368*	$3218*	$3868*
See Offers	$1918*	$2368*	$3218*	$3868*

Ports

Miami, Florida
Puerto Plata, Dominican Republic
San Juan, Puerto Rico
Gustavia, St. Barthelemy
Pointe-A-Pitre, Guadeloupe
Castries, St. Lucia
St. John's, Antigua
Costa Maya (Mahahual), Mexico
Harvest Caye, Belize
Coxen Hole, Roatan, Bay Islands, Honduras
Puerto Limon, Costa Rica
Colon, Panama
Cartagena, Colombia
Port Royal

View more ports

Ports

Miami, Florida - Puerto Plata, Dominican Republic - San Juan, Puerto Rico - Gustavia, St. Barthelemy - Pointe-A-Pitre, Guadeloupe - Castries, St. Lucia - St. John's, Antigua - Costa Maya (Mahahual), Mexico - Harvest Caye, Belize - Coxen Hole, Roatan, Bay Islands, Honduras - Puerto Limon, Costa Rica - Colon, Panama - Cartagena, Colombia - Port Royal - View more ports

22 Night Joyful Caribbean (Miami Roundtrip)

Vista M

4.3

(41 Reviews)

2024 sail dates: Dec 17

$7999*

$364/night*

Balcony

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 41 Vista reviews

Compare Prices

Partners	Bonus Offers	Inside	Oceanview	Balcony	Suite
		N/A	N/A	$7999*	$13699*

Ports

Tampa, Florida
Puerto Limon, Costa Rica
Colon, Panama
George Town, Grand Cayman

View more ports

Ports

Tampa, Florida - Puerto Limon, Costa Rica - Colon, Panama - George Town, Grand Cayman - View more ports

8 Night Panama Canal - Partial Transit (Tampa Roundtrip)

Carnival Legend L

3.9

(2185 Reviews)

2024 sail dates:

2025 sail dates: Feb 15

$1313*

$164/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 2185 Carnival Legend reviews

Compare Prices

Inside	Oceanview	Balcony	Suite
N/A	N/A	$2053*	$3949*
N/A	N/A	$2053*	$3949*
N/A	N/A	$2043*	$3939*
N/A	N/A	$2053*	$3949*
N/A	N/A	$2053*	$3949*
$1313*	N/A	$1953*	$3325*
$1313*	N/A	$1953*	$3325*
$1303*	N/A	$1943*	$3315*
$1313*	N/A	$1953*	$3325*
$1313*	N/A	$1953*	$3325*

Ports

Baltimore, Maryland
Half Moon Cay, Bahamas (Private Island)
Ocho Rios, Jamaica
Puerto Limon, Costa Rica
Colon, Panama
Grand Turk Island

View more ports

Ports

Baltimore, Maryland - Half Moon Cay, Bahamas (Private Island) - Ocho Rios, Jamaica - Puerto Limon, Costa Rica - Colon, Panama - Grand Turk Island - View more ports

14 Night Panama Canal: Carnival Journeys (Baltimore Roundtrip)

Carnival Pride L

4.0

(3004 Reviews)

2025 sail dates: Jan 12

$4349*

$311/night*

Suite

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 3004 Carnival Pride reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	N/A	N/A	N/A	$4349*
	N/A	N/A	N/A	$4349*
See Offers	N/A	N/A	N/A	$4349*
	N/A	N/A	N/A	$4349*

Ports

Ft. Lauderdale (Port Everglades), Florida
Kralendijk, Bonaire
Willemstad, Curacao
Cartagena, Colombia
Panama Canal (Cruise Into Canal)
Colon, Panama
Puerto Limon, Costa Rica
George Town, Grand Cayman

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Kralendijk, Bonaire - Willemstad, Curacao - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports

12 Night Panama Canal With Costa Rica & Caribbean (Ft. Lauderdale Roundtrip)

Emerald Princess L

4.0

(1206 Reviews)

2025 sail dates: Feb 28

$1248*

$104/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 1206 Emerald Princess reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1248*	$1898*	$2668*	$5029*
	$1248*	$1354*	$2756*	$4142*
See Offers	$1248*	$1354*	$2631*	$3799*
	$1248*	$1354*	$2756*	$4142*
	$1248*	$1354*	$2756*	$4142*
See Offers	$1248*	$1354*	$2668*	$4142*

Ports

Cartagena, Colombia
Kralendijk, Bonaire
Oranjestad, Aruba
Colon, Panama

View more ports

Ports

Cartagena, Colombia - Kralendijk, Bonaire - Oranjestad, Aruba - Colon, Panama - View more ports

7 Night Southern Caribbean Holiday (Cartagena Roundtrip)

Serenade of the Seas L

4.1

(1797 Reviews)

2025 sail dates: Dec 21

$1191*

$170/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 1797 Serenade of the Seas reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1191*	$1291*	$1404*	$1804*
See Offers	$1192*	$1292*	$1404*	$1804*
	$1191*	$1291*	$1404*	$1804*
	$1191*	$1291*	$1404*	$1804*
See Offers	$1192*	$1292*	$1404*	$1804*
	$1186*	$1286*	$1399*	$1799*
See Offers	$1192*	$1292*	$1404*	$1804*
	$1191*	$1291*	$1404*	$1804*

Ports

Colon, Panama
Cartagena, Colombia
Oranjestad, Aruba
Kralendijk, Bonaire

View more ports

Ports

Colon, Panama - Cartagena, Colombia - Oranjestad, Aruba - Kralendijk, Bonaire - View more ports

7 Night Southern Caribbean (Colon Roundtrip)

Serenade of the Seas L

4.1

(1797 Reviews)

2026 sail dates: Mar 28

$1122*

$160/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 1797 Serenade of the Seas reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1122*	$1222*	$1414*	$1851*
See Offers	$1123*	$1223*	$1415*	$1852*
	$1122*	$1222*	$1414*	$1851*
	$1122*	$1222*	$1414*	$1851*
See Offers	$1122*	$1222*	$1414*	$1851*
	$1117*	$1217*	$1409*	$1846*
See Offers	$1122*	$1222*	$1414*	$1851*
	$1122*	$1222*	$1414*	$1851*

161 - 170 of 228

All prices are per person based on double occupancy and do not include port/government fees and gratuities.

Colon, Panama cruises 228 Colon, Panama cruises

Your search Clear selections

228 cruises found

Sort by

Filter by