Acapulco, Mexico Cruises: Top Itineraries and Pricing

Ports

San Francisco, California
San Pedro (Los Angeles), California
Cabo San Lucas, Mexico
Acapulco, Mexico
Puerto Quetzal, Guatemala
Puerto Caldera, Costa Rica
Panama City, Panama
Panama Canal Transit
Cartagena, Colombia
Miami, Florida

Ports

San Francisco, California - San Pedro (Los Angeles), California - Cabo San Lucas, Mexico - Acapulco, Mexico - Puerto Quetzal, Guatemala - Puerto Caldera, Costa Rica - Panama City, Panama - Panama Canal Transit - Cartagena, Colombia - Miami, Florida - View more ports

18 Night Panama Canal: Mexico Costa Rica & Colombia (San Francisco To Miami)

Norwegian Joy L

4.2

(944 Reviews)

2025 sail dates: Oct 02

$2404*

$134/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$2404*	$3054*	$3504*	$9954*
See Offers	$2404*	$3054*	$3504*	$4104*
See Offers	$2404*	$3054*	$3504*	$4104*
See Offers	$2404*	$3054*	$3504*	$4104*
	$2404*	$3054*	$3504*	$4104*
See Offers	$2404*	$3054*	$3504*	$4104*
See Offers	$2404*	$3054*	$3504*	$4104*
See Offers	$2404*	$3054*	$3504*	$4104*

Ports

San Pedro (Los Angeles), California
Cabo San Lucas, Mexico
Acapulco, Mexico
Puerto Quetzal, Guatemala
Puerto Caldera, Costa Rica
Panama City, Panama
Panama Canal Transit
Cartagena, Colombia
Miami, Florida

View more ports

Ports

San Pedro (Los Angeles), California - Cabo San Lucas, Mexico - Acapulco, Mexico - Puerto Quetzal, Guatemala - Puerto Caldera, Costa Rica - Panama City, Panama - Panama Canal Transit - Cartagena, Colombia - Miami, Florida - View more ports

15 Night Panama Canal: Mexico Costa Rica & Colombia (Los Angeles To Miami)

Norwegian Joy L

4.2

(944 Reviews)

2025 sail dates: Oct 05

$2336*

$156/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$2336*	$2986*	$3436*	$9886*
See Offers	$2336*	$2986*	$3436*	$4036*
See Offers	$2336*	$2986*	$3436*	$4036*
See Offers	$2336*	$2986*	$3436*	$4036*
	$2336*	$2986*	$3436*	$4036*
See Offers	$2336*	$2986*	$3436*	$4036*
See Offers	$2336*	$2986*	$3436*	$4036*
See Offers	$2336*	$2986*	$3436*	$4036*

Ports

Miami, Florida
Cartagena, Colombia
Colon, Panama
Panama Canal Transit
Puerto Caldera, Costa Rica
Puerto Quetzal, Guatemala
Acapulco, Mexico
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Pedro (Los Angeles), California

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Ports

Miami, Florida - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Puerto Caldera, Costa Rica - Puerto Quetzal, Guatemala - Acapulco, Mexico - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - View more ports

16 Night Panama Canal: Mexico & Central America (Miami To Los Angeles)

Norwegian Joy L

4.2

(944 Reviews)

2025 sail dates: Jan 21

$1282*

$80/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1282*	$1632*	$1982*	$4912*
See Offers	$1282*	$1632*	$1982*	$2262*
See Offers	$1185*	$1483*	$1780*	$2018*
See Offers	$1282*	$1632*	$1982*	$2262*
	$1282*	$1632*	$1982*	$2262*
See Offers	$1185*	$1483*	$1780*	$2018*
See Offers	$1282*	$1632*	$1982*	$2262*
See Offers	$1282*	$1632*	$1982*	$2262*

Ports

Miami, Florida
Cartagena, Colombia
Colon, Panama
Panama Canal Transit
Puntarenas, Costa Rica
Puerto Quetzal, Guatemala
Acapulco, Mexico
Cabo San Lucas, Mexico
San Diego, California

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Ports

Miami, Florida - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Acapulco, Mexico - Cabo San Lucas, Mexico - San Diego, California - View more ports

15 Night Panama Canal: Mexico & Costa Rica (Miami To San Diego)

Norwegian Star L

3.6

(2053 Reviews)

2026 sail dates: Dec 04

$1918*

$128/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1918*	$2368*	$3218*	$4468*
See Offers	$1918*	$2368*	$3218*	$3868*
See Offers	$1918*	$2368*	$3218*	$3868*
See Offers	$1868*	$2318*	$3168*	$3818*
	$1918*	$2368*	$3218*	$3868*
See Offers	$1918*	$2368*	$3218*	$3868*
See Offers	$1918*	$2368*	$3218*	$3868*
See Offers	$1918*	$2368*	$3218*	$3868*

Ports

Seattle, Washington
San Francisco, California
San Pedro (Los Angeles), California
Cabo San Lucas, Mexico
Puerto Vallarta, Mexico
Manzanillo, Mexico
Acapulco, Mexico
Puerto Quetzal, Guatemala
Puntarenas, Costa Rica
Panama City, Panama
Panama Canal Transit
Cartagena, Colombia
Miami, Florida

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Ports

Seattle, Washington - San Francisco, California - San Pedro (Los Angeles), California - Cabo San Lucas, Mexico - Puerto Vallarta, Mexico - Manzanillo, Mexico - Acapulco, Mexico - Puerto Quetzal, Guatemala - Puntarenas, Costa Rica - Panama City, Panama - Panama Canal Transit - Cartagena, Colombia - Miami, Florida - View more ports

20 Night Panama Canal: Mexico & Costa Rica (Seattle To Miami)

Norwegian Encore XL

4.3

(693 Reviews)

2025 sail dates: Oct 19

$2258*

$113/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$2258*	$2928*	$3568*	$11298*
See Offers	$2258*	$2928*	$3568*	$4118*
See Offers	$2258*	$2928*	$3568*	$4118*
See Offers	$2258*	$2928*	$3568*	$4118*
	$2258*	$2928*	$3568*	$4118*
See Offers	$2258*	$2928*	$3568*	$4118*
See Offers	$2258*	$2928*	$3568*	$4118*
See Offers	$2258*	$2928*	$3568*	$4118*

Ports

Port Canaveral, Florida
Great Stirrup Cay (Cruise Line Private Island), Bahamas
Cartagena, Colombia
Panama Canal Transit
PANAMA CITY (COLON), PANAMA
Puntarenas, Costa Rica
Puerto Quetzal, Guatemala
Acapulco, Mexico
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Pedro (Los Angeles), California
San Francisco, California
Victoria, British Columbia
Seattle, Washington

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Ports

Port Canaveral, Florida - Great Stirrup Cay (Cruise Line Private Island), Bahamas - Cartagena, Colombia - Panama Canal Transit - PANAMA CITY (COLON), PANAMA - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Acapulco, Mexico - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - San Francisco, California - Victoria, British Columbia - Seattle, Washington - View more ports

23 Night Panama Canal: Mexico & Bahamas (Port Canaveral To Seattle)

Norwegian Joy L

4.2

(944 Reviews)

2026 sail dates: Apr 11

$3129*

$136/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$3129*	$4279*	$5519*	$13829*
See Offers	$2939*	$4279*	$5019*	$5829*
See Offers	$3129*	$4279*	$5519*	$6299*
See Offers	$2939*	$4279*	$5019*	$5829*
	$2939*	$4279*	$5019*	$5829*
See Offers	$3129*	$4279*	$5519*	$6299*
See Offers	$2939*	$4279*	$5019*	$5829*
See Offers	$2939*	$4279*	$5019*	$5829*

Ports

San Diego, California
Cabo San Lucas, Mexico
Acapulco, Mexico
Puerto Quetzal, Guatemala
Puntarenas, Costa Rica
Panama City, Panama
Panama Canal Transit
Cartagena, Colombia
Miami, Florida

View more ports

Ports

San Diego, California - Cabo San Lucas, Mexico - Acapulco, Mexico - Puerto Quetzal, Guatemala - Puntarenas, Costa Rica - Panama City, Panama - Panama Canal Transit - Cartagena, Colombia - Miami, Florida - View more ports

15 Night Panama Canal: Mexico & Costa Rica (San Diego To Miami)

Norwegian Star L

3.6

(2053 Reviews)

2027 sail dates: Apr 03

$2113*

$141/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$2113*	$2613*	$3663*	$4913*
See Offers	$2113*	$2613*	$3663*	$4363*
See Offers	$2113*	$2613*	$3663*	$4363*
See Offers	$2096*	$2596*	$3646*	$4346*
	$2113*	$2613*	$3663*	$4363*
See Offers	$2113*	$2613*	$3663*	$4363*
See Offers	$2113*	$2613*	$3663*	$4363*
See Offers	$2113*	$2613*	$3663*	$4363*

Ports

San Pedro (Los Angeles), California
Cabo San Lucas, Mexico
Acapulco, Mexico
Puerto Quetzal, Guatemala
Puerto Caldera, Costa Rica
Panama City, Panama
Panama Canal Transit
Cartagena, Colombia
Falmouth, Jamaica
Miami, Florida
New York, New York

View more ports

Ports

San Pedro (Los Angeles), California - Cabo San Lucas, Mexico - Acapulco, Mexico - Puerto Quetzal, Guatemala - Puerto Caldera, Costa Rica - Panama City, Panama - Panama Canal Transit - Cartagena, Colombia - Falmouth, Jamaica - Miami, Florida - New York, New York - View more ports

19 Night Panama Canal: Mexico & Jamaica (Los Angeles To New York)

Norwegian Bliss XL

4.1

(1347 Reviews)

2026 sail dates: Oct 13

$2346*

$123/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$2346*	$3096*	$3796*	$10846*
See Offers	$2346*	$3096*	$3796*	$4396*
See Offers	$2346*	$3096*	$3796*	$4396*
See Offers	$2346*	$3096*	$3796*	$4396*
	$2346*	$3096*	$3796*	$4396*
See Offers	$2346*	$3096*	$3796*	$4396*
See Offers	$2346*	$3096*	$3796*	$4396*
See Offers	$2346*	$3096*	$3796*	$4396*

Ports

Tampa, Florida
Cartagena, Colombia
Colon, Panama
Panama Canal Transit
Puerto Caldera, Costa Rica
San Juan Del Sur, Nicaragua
Puerto Quetzal, Guatemala
Acapulco, Mexico
Cabo San Lucas, Mexico
San Pedro (Los Angeles), California
San Francisco, California
Astoria, Oregon
KETCHIKAN (WARD COVE), ALASKA
Juneau, Alaska
Skagway, Alaska
Cruise Hubbard Glacier
Whittier (Anchorage), Alaska

View more ports

Ports

Tampa, Florida - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Puerto Caldera, Costa Rica - San Juan Del Sur, Nicaragua - Puerto Quetzal, Guatemala - Acapulco, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - San Francisco, California - Astoria, Oregon - KETCHIKAN (WARD COVE), ALASKA - Juneau, Alaska - Skagway, Alaska - Cruise Hubbard Glacier - Whittier (Anchorage), Alaska - View more ports

25 Night Panama Canal: Alaska & Mexico (Tampa To Whittier)

Norwegian Jade L

3.9

(1405 Reviews)

2025 sail dates: Apr 03

$2505*

$100/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$2505*	$2605*	$4405*	$12175*
See Offers	$2354*	$2605*	$4405*	$4705*
See Offers	$2505*	$2605*	$4405*	$4705*
See Offers	$2354*	$2605*	$4405*	$4705*
	$2354*	$2605*	$4405*	$4705*
See Offers	$2505*	$2605*	$4405*	$4705*
See Offers	$2354*	$2605*	$4405*	$4705*
See Offers	$2354*	$2605*	$4405*	$4705*

Ports

Miami, Florida
George Town, Grand Cayman
Cartagena, Colombia
Panama Canal Transit
Puntarenas, Costa Rica
Puerto Corinto, Nicaragua
Puerto Quetzal, Guatemala
Acapulco, Mexico
Cabo San Lucas, Mexico
Ensenada, Mexico
San Pedro (Los Angeles), California

View more ports

Ports

Miami, Florida - George Town, Grand Cayman - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Corinto, Nicaragua - Puerto Quetzal, Guatemala - Acapulco, Mexico - Cabo San Lucas, Mexico - Ensenada, Mexico - San Pedro (Los Angeles), California - View more ports

16 Night Tropical Holiday (Miami To Los Angeles)

Seven Seas Grandeur M

4.1

(7 Reviews)

2024 sail dates: Dec 13

$10499*

$656/night*

Suite

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Partners	Bonus Offers	Inside	Oceanview	Balcony	Suite
		N/A	N/A	N/A	$10499*
		N/A	N/A	N/A	$10499*

Acapulco, Mexico cruises 41 Acapulco, Mexico cruises

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