Panama City, Panama cruises 40 Panama City, Panama cruises

Your search Clear selections

Any Destination
All Sail Months
Any Length
Panama City, Panama
Any Cruise Line
Any Ship

Close

40 cruises found

Sort by

Filter by

Ports

  • Panama City, Panama
  • Puntarenas, Costa Rica
  • Puerto Corinto, Nicaragua
  • Puerto Vallarta, Mexico
  • Cabo San Lucas, Mexico
  • Ensenada, Mexico
  • Los Angeles, California
View more ports

Ports

Panama City, Panama - Puntarenas, Costa Rica - Puerto Corinto, Nicaragua - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - Ensenada, Mexico - Los Angeles, California - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$6799*

See Offers

$18199*

N/A

N/A

$6799*

 

N/A

N/A

N/A

$6799*

 

N/A

N/A

N/A

$6799*

See Offers

N/A

N/A

N/A

$6799*

Ports

  • Miami, Florida
  • Cozumel, Mexico
  • Costa Maya (Mahahual), Mexico
  • Harvest Caye, Belize
  • Santo Tomas De Castilla, Guatemala
  • Coxen Hole, Roatan, Bay Islands, Honduras
  • Puerto Limon, Costa Rica
  • Panama Canal Transit
  • Panama City, Panama
View more ports

Ports

Miami, Florida - Cozumel, Mexico - Costa Maya (Mahahual), Mexico - Harvest Caye, Belize - Santo Tomas De Castilla, Guatemala - Coxen Hole, Roatan, Bay Islands, Honduras - Puerto Limon, Costa Rica - Panama Canal Transit - Panama City, Panama - View more ports

Ports

  • Miami, Florida
  • Cozumel, Mexico
  • Costa Maya (Mahahual), Mexico
  • Harvest Caye, Belize
  • Santo Tomas De Castilla, Guatemala
  • Coxen Hole, Roatan, Bay Islands, Honduras
  • Puerto Limon, Costa Rica
  • Panama Canal Transit
  • Panama City, Panama
  • Cartagena, Colombia
  • Kralendijk, Bonaire
  • Willemstad, Curacao
  • Oranjestad, Aruba
  • Port Antonio, Jamaica
View more ports

Ports

Miami, Florida - Cozumel, Mexico - Costa Maya (Mahahual), Mexico - Harvest Caye, Belize - Santo Tomas De Castilla, Guatemala - Coxen Hole, Roatan, Bay Islands, Honduras - Puerto Limon, Costa Rica - Panama Canal Transit - Panama City, Panama - Cartagena, Colombia - Kralendijk, Bonaire - Willemstad, Curacao - Oranjestad, Aruba - Port Antonio, Jamaica - View more ports

Ports

  • Panama City, Panama
  • Panama Canal Transit
  • Cartagena, Colombia
  • Kralendijk, Bonaire
  • Willemstad, Curacao
  • Oranjestad, Aruba
  • Port Antonio, Jamaica
  • Miami, Florida
View more ports

Ports

Panama City, Panama - Panama Canal Transit - Cartagena, Colombia - Kralendijk, Bonaire - Willemstad, Curacao - Oranjestad, Aruba - Port Antonio, Jamaica - Miami, Florida - View more ports

Ports

  • Miami, Florida
  • Cozumel, Mexico
  • Costa Maya (Mahahual), Mexico
  • Harvest Caye, Belize
  • Coxen Hole, Roatan, Bay Islands, Honduras
  • George Town, Grand Cayman
  • Ocho Rios, Jamaica
  • Puerto Limon, Costa Rica
  • Cartagena, Colombia
  • Panama City, Panama
  • Panama Canal Transit
  • Puntarenas, Costa Rica
  • Puerto Corinto, Nicaragua
  • Acajutla
  • Puerto Quetzal, Guatemala
  • Puerto Vallarta, Mexico
  • Cabo San Lucas, Mexico
  • San Pedro (Los Angeles), California
  • Honolulu, Oahu
  • Kahului, Maui
  • Hilo, Hawaii
  • Bora Bora, French Polynesia
  • Moorea, French Polynesia
  • Papeete, Tahiti
  • Huahine, French Polynesia
  • Raiatea, French Polynesia
  • Pago Pago, American Samoa
  • Cross International Dateline
  • Apia, Samoa
  • Suva, Fiji
  • Lautoka, Fiji Islands
  • Mystery Island, Vanuatu
  • Lifou Isle, New Caledonia
  • Brisbane, Australia
  • Sydney, Australia
  • Townsville, Australia
  • Cairns, Australia
  • Cooktown, Australia
  • Darwin, Australia
  • Komodo Island, Indonesia
  • Benoa, Bali, Indonesia
  • Surabaya, Java, Indonesia
  • Semarang, Java, Indonesia
  • Singapore
  • Port Klang (Kuala Lumpur), Malaysia
  • Penang (Pulau Pinang), Malaysia
  • Phuket, Thailand
  • Colombo, Sri Lanka
  • Male, Maldives
  • Cochin, India
  • New Mangalore Port, India
  • Mormugao (Goa), India
  • Mumbai (Bombay), India
  • Muscat, Oman
  • Dubai, U.A.E.
  • Doha, Qatar
  • Abu Dhabi, U.A.E.
  • Salalah, Oman
  • Jeddah, Saudi Arabia
  • Safaga (Luxor), Egypt
  • Aqaba (Petra), Jordan
  • Suez Canal Transit
  • HAIFA (JERUSALEM), ISRAEL
  • Limassol, Cyprus
  • Rhodes, Greece
  • Kusadasi (Ephesus), Turkey
  • Piraeus (Athens), Greece
  • Sorrento, Italy
  • Civitavecchia (Rome), Italy
View more ports

Ports

Miami, Florida - Cozumel, Mexico - Costa Maya (Mahahual), Mexico - Harvest Caye, Belize - Coxen Hole, Roatan, Bay Islands, Honduras - George Town, Grand Cayman - Ocho Rios, Jamaica - Puerto Limon, Costa Rica - Cartagena, Colombia - Panama City, Panama - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Corinto, Nicaragua - Acajutla - Puerto Quetzal, Guatemala - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - Honolulu, Oahu - Kahului, Maui - Hilo, Hawaii - Bora Bora, French Polynesia - Moorea, French Polynesia - Papeete, Tahiti - Huahine, French Polynesia - Raiatea, French Polynesia - Pago Pago, American Samoa - Cross International Dateline - Apia, Samoa - Suva, Fiji - Lautoka, Fiji Islands - Mystery Island, Vanuatu - Lifou Isle, New Caledonia - Brisbane, Australia - Sydney, Australia - Townsville, Australia - Cairns, Australia - Cooktown, Australia - Darwin, Australia - Komodo Island, Indonesia - Benoa, Bali, Indonesia - Surabaya, Java, Indonesia - Semarang, Java, Indonesia - Singapore - Port Klang (Kuala Lumpur), Malaysia - Penang (Pulau Pinang), Malaysia - Phuket, Thailand - Colombo, Sri Lanka - Male, Maldives - Cochin, India - New Mangalore Port, India - Mormugao (Goa), India - Mumbai (Bombay), India - Muscat, Oman - Dubai, U.A.E. - Doha, Qatar - Abu Dhabi, U.A.E. - Salalah, Oman - Jeddah, Saudi Arabia - Safaga (Luxor), Egypt - Aqaba (Petra), Jordan - Suez Canal Transit - HAIFA (JERUSALEM), ISRAEL - Limassol, Cyprus - Rhodes, Greece - Kusadasi (Ephesus), Turkey - Piraeus (Athens), Greece - Sorrento, Italy - Civitavecchia (Rome), Italy - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$81799*

 

N/A

N/A

N/A

$81609*

 

N/A

N/A

N/A

$81609*

See Offers

N/A

N/A

N/A

$81799*

Ports

  • Miami, Florida
  • Cozumel, Mexico
  • Costa Maya (Mahahual), Mexico
  • Harvest Caye, Belize
  • Coxen Hole, Roatan, Bay Islands, Honduras
  • George Town, Grand Cayman
  • Ocho Rios, Jamaica
  • Puerto Limon, Costa Rica
  • Cartagena, Colombia
  • Panama Canal Transit
  • Panama City, Panama
  • Puntarenas, Costa Rica
  • Puerto Corinto, Nicaragua
  • Acajutla
  • Puerto Quetzal, Guatemala
  • Puerto Vallarta, Mexico
  • Cabo San Lucas, Mexico
  • San Pedro (Los Angeles), California
  • Honolulu, Oahu
  • Kahului, Maui
  • Hilo, Hawaii
  • Bora Bora, French Polynesia
  • Papeete, Tahiti
  • Moorea, French Polynesia
  • Huahine, French Polynesia
  • Raiatea, French Polynesia
  • Pago Pago, American Samoa
  • Cross International Dateline
  • Apia, Samoa
  • Suva, Fiji
  • Lautoka, Fiji Islands
  • Mystery Island, Vanuatu
  • Lifou Isle, New Caledonia
  • Brisbane, Australia
  • Sydney, Australia
  • Townsville, Australia
  • Cairns, Australia
  • Cooktown, Australia
  • Darwin, Australia
  • Komodo Island, Indonesia
  • Benoa, Bali, Indonesia
  • Surabaya, Java, Indonesia
  • Semarang, Java, Indonesia
  • Singapore
  • Port Klang (Kuala Lumpur), Malaysia
  • Penang (Pulau Pinang), Malaysia
  • Phuket, Thailand
  • Colombo, Sri Lanka
  • Male, Maldives
  • Cochin, India
  • New Mangalore Port, India
  • Mormugao (Goa), India
  • Mumbai (Bombay), India
  • Muscat, Oman
  • Dubai, U.A.E.
  • Doha, Qatar
  • Abu Dhabi, U.A.E.
  • Salalah, Oman
  • Jeddah, Saudi Arabia
  • Safaga (Luxor), Egypt
  • Aqaba (Petra), Jordan
  • Suez Canal Transit
  • HAIFA (JERUSALEM), ISRAEL
  • Limassol, Cyprus
  • Rhodes, Greece
  • Kusadasi (Ephesus), Turkey
  • Piraeus (Athens), Greece
  • Sorrento, Italy
  • Civitavecchia (Rome), Italy
  • Barcelona, Spain
  • Alicante, Spain
  • Malaga, Spain
  • Casablanca, Morocco
  • Royal Naval Dockyard, West End, Bermuda
  • New York, New York
View more ports

Ports

Miami, Florida - Cozumel, Mexico - Costa Maya (Mahahual), Mexico - Harvest Caye, Belize - Coxen Hole, Roatan, Bay Islands, Honduras - George Town, Grand Cayman - Ocho Rios, Jamaica - Puerto Limon, Costa Rica - Cartagena, Colombia - Panama Canal Transit - Panama City, Panama - Puntarenas, Costa Rica - Puerto Corinto, Nicaragua - Acajutla - Puerto Quetzal, Guatemala - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - Honolulu, Oahu - Kahului, Maui - Hilo, Hawaii - Bora Bora, French Polynesia - Papeete, Tahiti - Moorea, French Polynesia - Huahine, French Polynesia - Raiatea, French Polynesia - Pago Pago, American Samoa - Cross International Dateline - Apia, Samoa - Suva, Fiji - Lautoka, Fiji Islands - Mystery Island, Vanuatu - Lifou Isle, New Caledonia - Brisbane, Australia - Sydney, Australia - Townsville, Australia - Cairns, Australia - Cooktown, Australia - Darwin, Australia - Komodo Island, Indonesia - Benoa, Bali, Indonesia - Surabaya, Java, Indonesia - Semarang, Java, Indonesia - Singapore - Port Klang (Kuala Lumpur), Malaysia - Penang (Pulau Pinang), Malaysia - Phuket, Thailand - Colombo, Sri Lanka - Male, Maldives - Cochin, India - New Mangalore Port, India - Mormugao (Goa), India - Mumbai (Bombay), India - Muscat, Oman - Dubai, U.A.E. - Doha, Qatar - Abu Dhabi, U.A.E. - Salalah, Oman - Jeddah, Saudi Arabia - Safaga (Luxor), Egypt - Aqaba (Petra), Jordan - Suez Canal Transit - HAIFA (JERUSALEM), ISRAEL - Limassol, Cyprus - Rhodes, Greece - Kusadasi (Ephesus), Turkey - Piraeus (Athens), Greece - Sorrento, Italy - Civitavecchia (Rome), Italy - Barcelona, Spain - Alicante, Spain - Malaga, Spain - Casablanca, Morocco - Royal Naval Dockyard, West End, Bermuda - New York, New York - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$89799*

 

N/A

N/A

N/A

$89609*

 

N/A

N/A

N/A

$89609*

See Offers

N/A

N/A

N/A

$89799*

Ports

  • Miami, Florida
  • Costa Maya (Mahahual), Mexico
  • Harvest Caye, Belize
  • Coxen Hole, Roatan, Bay Islands, Honduras
  • George Town, Grand Cayman
  • Ocho Rios, Jamaica
  • Puerto Limon, Costa Rica
  • Cartagena, Colombia
  • Colon, Panama
  • Panama City, Panama
  • Panama Canal Transit
View more ports

Ports

Miami, Florida - Costa Maya (Mahahual), Mexico - Harvest Caye, Belize - Coxen Hole, Roatan, Bay Islands, Honduras - George Town, Grand Cayman - Ocho Rios, Jamaica - Puerto Limon, Costa Rica - Cartagena, Colombia - Colon, Panama - Panama City, Panama - Panama Canal Transit - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$8799*

 

N/A

N/A

N/A

$8799*

 

N/A

N/A

N/A

$8799*

See Offers

N/A

N/A

N/A

$8799*

Ports

  • Panama City, Panama
  • Panama Canal Transit
  • Oranjestad, Aruba
  • Port of Spain
  • Macapa, Brazil
  • Santarem, Brazil
  • Boca Da Valeria, Brazil
  • Manaus, Brazil
  • Parintins, Brazil
  • Alter Do Chao, Brazil
  • St. George's, Grenada
  • Willemstad, Curacao
View more ports

Ports

Panama City, Panama - Panama Canal Transit - Oranjestad, Aruba - Port of Spain - Macapa, Brazil - Santarem, Brazil - Boca Da Valeria, Brazil - Manaus, Brazil - Parintins, Brazil - Alter Do Chao, Brazil - St. George's, Grenada - Willemstad, Curacao - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$11499*

 

N/A

N/A

N/A

$11499*

 

N/A

N/A

N/A

$11499*

See Offers

N/A

N/A

N/A

$11499*

Ports

  • Callao (Lima), Peru
  • Salaverry (Trujillo), Peru
  • Guayaquil, Equador
  • Manta, Ecuador
  • Golfito, Costa Rica
  • Panama City, Panama
  • Panama Canal Transit
  • Puerto Limon, Costa Rica
  • Coxen Hole, Roatan, Bay Islands, Honduras
  • Harvest Caye, Belize
  • Costa Maya (Mahahual), Mexico
  • Miami, Florida
View more ports

Ports

Callao (Lima), Peru - Salaverry (Trujillo), Peru - Guayaquil, Equador - Manta, Ecuador - Golfito, Costa Rica - Panama City, Panama - Panama Canal Transit - Puerto Limon, Costa Rica - Coxen Hole, Roatan, Bay Islands, Honduras - Harvest Caye, Belize - Costa Maya (Mahahual), Mexico - Miami, Florida - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$11199*

 

N/A

N/A

N/A

$11199*

 

N/A

N/A

N/A

$11199*

See Offers

N/A

N/A

N/A

$11199*

Ports

  • Tampa, Florida
  • Key West, Florida
  • Cozumel, Mexico
  • George Town, Grand Cayman
  • Ocho Rios, Jamaica
  • Cartagena, Colombia
  • Colon, Panama
  • Puerto Limon, Costa Rica
  • Panama Canal Transit
  • Panama City, Panama
View more ports

Ports

Tampa, Florida - Key West, Florida - Cozumel, Mexico - George Town, Grand Cayman - Ocho Rios, Jamaica - Cartagena, Colombia - Colon, Panama - Puerto Limon, Costa Rica - Panama Canal Transit - Panama City, Panama - View more ports

All prices are per person based on double occupancy and do not include port/government fees and gratuities.