Panama Canal, Central America Cruises : Best Cruise Prices

Ports

San Francisco, California
Los Angeles, California
Cabo San Lucas, Mexico
Puntarenas, Costa Rica
Panama Canal Transit
Cartagena, Colombia
Oranjestad, Aruba
Miami, Florida
San Juan, Puerto Rico
St. John's, Antigua
Castries, St. Lucia
Bridgetown, Barbados
Philipsburg, St. Maarten
Tortola, British Virgin Islands

Ports

San Francisco, California - Los Angeles, California - Cabo San Lucas, Mexico - Puntarenas, Costa Rica - Panama Canal Transit - Cartagena, Colombia - Oranjestad, Aruba - Miami, Florida - San Juan, Puerto Rico - St. John's, Antigua - Castries, St. Lucia - Bridgetown, Barbados - Philipsburg, St. Maarten - Tortola, British Virgin Islands - View more ports

30 Night Panama Canal (San Francisco To Miami)

Queen Elizabeth M

3.9

(126 Reviews)

2025 sail dates: Sep 28

$4539*

$151/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$4539*	$5189*	$6089*	N/A
See Offers	$4199*	$4849*	$5849*	$14999*
See Offers	$4199*	$4849*	$5849*	$14999*
See Offers	$4199*	$4849*	$5849*	$14999*
	$4199*	$4849*	$5849*	$14999*
See Offers	$4199*	$4849*	$5699*	$14999*
See Offers	$4199*	$4849*	$5699*	$14999*
	N/A	N/A	N/A	$15011*
See Offers	$4199*	$4849*	$5699*	$14999*

Ports

San Francisco, California
Los Angeles, California
Cabo San Lucas, Mexico
Puntarenas, Costa Rica
Panama Canal Transit
Cartagena, Colombia
Oranjestad, Aruba
Miami, Florida

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Ports

San Francisco, California - Los Angeles, California - Cabo San Lucas, Mexico - Puntarenas, Costa Rica - Panama Canal Transit - Cartagena, Colombia - Oranjestad, Aruba - Miami, Florida - View more ports

18 Night Panama Canal (San Francisco To Miami)

Queen Elizabeth M

3.9

(126 Reviews)

2025 sail dates: Sep 28

$3127*

$174/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$3127*	$3427*	$4127*	N/A
See Offers	$2799*	$3099*	$3899*	$9499*
See Offers	$2799*	$3099*	$3899*	$9499*
See Offers	$2799*	$3099*	$3899*	$9499*
	$2799*	$3099*	$3899*	$9499*
See Offers	$2799*	$3099*	$3799*	$9499*
See Offers	$2799*	$3099*	$3799*	$9499*
	N/A	N/A	N/A	$9511*
See Offers	$2799*	$3099*	$3799*	$9499*

Ports

Los Angeles, California
Cabo San Lucas, Mexico
Puerto Corinto, Nicaragua
Puntarenas, Costa Rica
Panama Canal Transit
Colon, Panama
Cartagena, Colombia
Willemstad, Curacao
San Juan, Puerto Rico

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Ports

Los Angeles, California - Cabo San Lucas, Mexico - Puerto Corinto, Nicaragua - Puntarenas, Costa Rica - Panama Canal Transit - Colon, Panama - Cartagena, Colombia - Willemstad, Curacao - San Juan, Puerto Rico - View more ports

17 Night West Indies & Panama Canal Passage (Los Angeles To San Juan)

Viking Sea S

4.3

(82 Reviews)

2025 sail dates: Oct 02

$6499*

$382/night*

Balcony

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	N/A	N/A	$6499*	$12999*
See Offers	N/A	N/A	$6499*	$12999*
See Offers	N/A	N/A	$6499*	$12999*
	N/A	N/A	$6499*	$12999*
See Offers	N/A	N/A	$6499*	$12999*
See Offers	N/A	N/A	$6499*	$12999*

Ports

San Diego, California
Cabo San Lucas, Mexico
Mazatlan, Mexico
Puerto Quetzal, Guatemala
Puntarenas, Costa Rica
Panama Canal Transit
Colon, Panama
Cartagena, Colombia
George Town, Grand Cayman
Ft. Lauderdale (Port Everglades), Florida

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Ports

San Diego, California - Cabo San Lucas, Mexico - Mazatlan, Mexico - Puerto Quetzal, Guatemala - Puntarenas, Costa Rica - Panama Canal Transit - Colon, Panama - Cartagena, Colombia - George Town, Grand Cayman - Ft. Lauderdale (Port Everglades), Florida - View more ports

16 Night Panama Canal (San Diego To Ft. Lauderdale)

Radiance of the Seas L

4.1

(1232 Reviews)

2025 sail dates: Oct 04

$953*

$60/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$953*	$789*	$3607*	N/A
See Offers	$953*	$789*	$3607*	N/A
See Offers	$953*	$789*	$3607*	N/A
	$953*	$789*	$3607*	N/A
See Offers	$953*	$1023*	$3607*	N/A
	$755*	$801*	$1099*	N/A
See Offers	$953*	$1023*	$3607*	N/A
See Offers	$953*	$1023*	$3607*	N/A
See Offers	$953*	$1023*	$3607*	N/A

Ports

Ft. Lauderdale (Port Everglades), Florida
Half Moon Cay, Bahamas (Private Island)
Willemstad, Curacao
Cartagena, Colombia
Panama Canal (Cruise Into Canal)
Colon, Panama
Puerto Limon, Costa Rica
George Town, Grand Cayman
Kralendijk, Bonaire
Oranjestad, Aruba

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Ports

Ft. Lauderdale (Port Everglades), Florida - Half Moon Cay, Bahamas (Private Island) - Willemstad, Curacao - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - George Town, Grand Cayman - Kralendijk, Bonaire - Oranjestad, Aruba - View more ports

21 Night Panama Canal & Southern Caribbean: Abc Islands (Ft. Lauderdale Roundtrip)

Rotterdam L

4.4

(237 Reviews)

2025 sail dates: Oct 26

2026 sail dates: Feb 08, Mar 01

$1994*

$95/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1994*	$2894*	$3294*	$4794*
See Offers	$1994*	$2894*	$3294*	$4794*
See Offers	$1994*	$2894*	$3294*	$4794*
See Offers	$1994*	$2894*	$3294*	$4794*
	$1994*	$2894*	$3294*	$4794*
	N/A	N/A	N/A	$4806*
See Offers	$1994*	$2894*	$3294*	$4794*
See Offers	$1994*	$2894*	$3294*	$4794*
See Offers	$1994*	$2894*	$3294*	$4794*
	$2444*	$3344*	$3794*	$5494*
See Offers	$2357*	$3104*	$3509*	$5494*
See Offers	$2357*	$3104*	$3509*	$5494*
See Offers	$2357*	$3104*	$3509*	$5494*
	$2357*	$3104*	$3509*	$5494*
	N/A	N/A	N/A	$5506*
See Offers	$2444*	$3344*	$3794*	$5494*
See Offers	$2444*	$3344*	$3794*	$5494*
See Offers	$2444*	$3344*	$3794*	$5494*
	$2344*	$3244*	$3694*	$5394*
See Offers	$2344*	$3244*	$3694*	$5394*
See Offers	$2344*	$3244*	$3694*	$5394*
See Offers	$2344*	$3244*	$3694*	$5394*
	$2344*	$3244*	$3694*	$5394*
	N/A	N/A	N/A	$5406*
See Offers	$2344*	$3244*	$3694*	$5394*
See Offers	$2344*	$3244*	$3694*	$5394*
See Offers	$2344*	$3244*	$3694*	$5394*

Ports

Ft. Lauderdale (Port Everglades), Florida
Half Moon Cay, Bahamas (Private Island)
Willemstad, Curacao
Cartagena, Colombia
Colon, Panama
Panama Canal (Cruise Into Canal)
Puerto Limon, Costa Rica
George Town, Grand Cayman

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Ports

Ft. Lauderdale (Port Everglades), Florida - Half Moon Cay, Bahamas (Private Island) - Willemstad, Curacao - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports

12 Night Panama Canal Discovery: Costa Rica & Greater Antilles (Ft. Lauderdale Roundtrip)

Rotterdam L

4.4

(237 Reviews)

2025 sail dates: Oct 26, Dec 07

2026 sail dates: Feb 08, Mar 01

$1029*

$86/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1129*	$1779*	$2029*	$2979*
See Offers	$1097*	$1655*	$1880*	$2979*
See Offers	$1097*	$1655*	$1880*	$2979*
See Offers	$1097*	$1655*	$1880*	$2979*
	$1097*	$1655*	$1880*	$2979*
	N/A	N/A	N/A	$2991*
See Offers	$1129*	$1779*	$2029*	$2979*
See Offers	$1129*	$1779*	$2029*	$2979*
See Offers	$1129*	$1779*	$2029*	$2979*
	$1029*	$1679*	$1929*	$2879*
See Offers	$1007*	$1565*	$1790*	$2879*
See Offers	$1007*	$1565*	$1790*	$2879*
See Offers	$1007*	$1565*	$1790*	$2879*
	$1007*	$1565*	$1790*	$2879*
	N/A	N/A	N/A	$2891*
See Offers	$1029*	$1679*	$1929*	$2879*
See Offers	$1029*	$1679*	$1929*	$2879*
See Offers	$1029*	$1679*	$1929*	$2879*
	$1429*	$2079*	$2329*	$3329*
See Offers	$1367*	$1925*	$2150*	$3329*
See Offers	$1367*	$1925*	$2150*	$3329*
See Offers	$1367*	$1925*	$2150*	$3329*
	$1367*	$1925*	$2150*	$3329*
	N/A	N/A	N/A	$3341*
See Offers	$1429*	$2079*	$2329*	$3329*
See Offers	$1429*	$2079*	$2329*	$3329*
See Offers	$1429*	$2079*	$2329*	$3329*
	$1329*	$1979*	$2229*	$3229*
See Offers	$1277*	$1835*	$2060*	$3229*
See Offers	$1277*	$1835*	$2060*	$3229*
See Offers	$1277*	$1835*	$2060*	$3229*
	$1277*	$1835*	$2060*	$3229*
	N/A	N/A	N/A	$3241*
See Offers	$1329*	$1979*	$2229*	$3229*
See Offers	$1329*	$1979*	$2229*	$3229*
See Offers	$1329*	$1979*	$2229*	$3229*

Ports

San Diego, California
Puerto Vallarta, Mexico
Huatulco, Mexico
Puerto Chiapas (Tapachula), Mexico
Puerto Quetzal, Guatemala
Puntarenas, Costa Rica
Panama Canal Transit
Oranjestad, Aruba
Half Moon Cay, Bahamas (Private Island)
Ft. Lauderdale (Port Everglades), Florida

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Ports

San Diego, California - Puerto Vallarta, Mexico - Huatulco, Mexico - Puerto Chiapas (Tapachula), Mexico - Puerto Quetzal, Guatemala - Puntarenas, Costa Rica - Panama Canal Transit - Oranjestad, Aruba - Half Moon Cay, Bahamas (Private Island) - Ft. Lauderdale (Port Everglades), Florida - View more ports

17 Night Panama Canal (San Diego To Ft. Lauderdale)

Koningsdam L

4.3

(547 Reviews)

2025 sail dates: Nov 01

$1779*

$105/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1779*	$2579*	$2879*	$4179*
See Offers	$1779*	$2579*	$2879*	$4179*
See Offers	$1779*	$2579*	$2879*	$4179*
See Offers	$1779*	$2579*	$2879*	$4179*
	$1779*	$2579*	$2879*	$4179*
	N/A	N/A	N/A	$4191*
See Offers	$1779*	$2579*	$2879*	$4179*
See Offers	$1779*	$2579*	$2879*	$4179*
See Offers	$1779*	$2579*	$2879*	$4179*

Ports

San Pedro (Los Angeles), California
Ensenada, Mexico
Cabo San Lucas, Mexico
Acapulco, Mexico
Puerto Quetzal, Guatemala
Puerto Corinto, Nicaragua
Puntarenas, Costa Rica
Panama Canal Transit
Colon, Panama

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Ports

San Pedro (Los Angeles), California - Ensenada, Mexico - Cabo San Lucas, Mexico - Acapulco, Mexico - Puerto Quetzal, Guatemala - Puerto Corinto, Nicaragua - Puntarenas, Costa Rica - Panama Canal Transit - Colon, Panama - View more ports

12 Night Pacific Pathways (Los Angeles To Colon)

Regatta S

4.1

(126 Reviews)

2025 sail dates: Nov 02

$3599*

$300/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$3599*	$3949*	$5849*	$8199*
See Offers	$3599*	$3949*	$5849*	$8199*
See Offers	$3599*	$3949*	$5849*	$8199*
	$3599*	$3949*	$5849*	$8199*
See Offers	$3599*	$3949*	$5849*	$8199*
See Offers	$3599*	$3949*	$5849*	$8199*
See Offers	$3599*	$3949*	$5849*	$8199*

Ports

Ft. Lauderdale (Port Everglades), Florida
Willemstad, Curacao
Kralendijk, Bonaire
Oranjestad, Aruba
Half Moon Cay, Bahamas (Private Island)
Cartagena, Colombia
Panama Canal (Cruise Into Canal)
Colon, Panama
Puerto Limon, Costa Rica
Falmouth, Jamaica

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Ports

Ft. Lauderdale (Port Everglades), Florida - Willemstad, Curacao - Kralendijk, Bonaire - Oranjestad, Aruba - Half Moon Cay, Bahamas (Private Island) - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - Falmouth, Jamaica - View more ports

21 Night Southern Caribbean & Panama Canal: Abc Islands (Ft. Lauderdale Roundtrip)

Rotterdam L

4.4

(237 Reviews)

2025 sail dates: Nov 07

$1994*

$95/night*

Inside

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1994*	$2894*	$3294*	$4794*
See Offers	$1994*	$2894*	$3294*	$4794*
See Offers	$1994*	$2894*	$3294*	$4794*
See Offers	$1994*	$2894*	$3294*	$4794*
	$1994*	$2894*	$3294*	$4794*
	N/A	N/A	N/A	$4806*
See Offers	$1994*	$2894*	$3294*	$4794*
See Offers	$1994*	$2894*	$3294*	$4794*
See Offers	$1994*	$2894*	$3294*	$4794*

Ports

Miami, Florida
San Juan, Puerto Rico
Prickly Pear Island, B.V.I.
Gustavia, St. Barthelemy
Terre-De-Haut, Iles Des Saintes, Guadeloupe
Roseau, Dominica
SOUTH FRIARS BAY, ST. KITTS
Jost Van Dyke, B.V.I.
Catalina Island (Isla Catalina), Dominican Republic
Willemstad, Curacao
Santa Marta, Colombia
Panama Canal Transit
Golfito, Costa Rica
Puntarenas, Costa Rica
Puerto Quetzal, Guatemala
Puerto Chiapas (Tapachula), Mexico
Huatulco, Mexico
Cabo San Lucas, Mexico
San Pedro (Los Angeles), California

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Ports

Miami, Florida - San Juan, Puerto Rico - Prickly Pear Island, B.V.I. - Gustavia, St. Barthelemy - Terre-De-Haut, Iles Des Saintes, Guadeloupe - Roseau, Dominica - SOUTH FRIARS BAY, ST. KITTS - Jost Van Dyke, B.V.I. - Catalina Island (Isla Catalina), Dominican Republic - Willemstad, Curacao - Santa Marta, Colombia - Panama Canal Transit - Golfito, Costa Rica - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Puerto Chiapas (Tapachula), Mexico - Huatulco, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - View more ports

34 Night Caribbean Gems & Panama Canal (Miami To Los Angeles)

Seabourn Sojourn S

4.4

(39 Reviews)

2025 sail dates: Nov 13

$11434*

$336/night*

Suite

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	N/A	N/A	N/A	$11434*
See Offers	N/A	N/A	N/A	$11434*
See Offers	N/A	N/A	N/A	$11434*
	N/A	N/A	N/A	$11434*
	N/A	N/A	N/A	$11446*
See Offers	N/A	N/A	N/A	$11434*

Panama Canal, Central America cruises 325 Panama Canal, Central America Cruises Found

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