Panama Canal, Central America cruises 346 Panama Canal, Central America Cruises Found
Your search Clear selections
346 cruises found
Sort by
Filter by
Ports
- San Juan, Puerto Rico
- Catalina Island (Isla Catalina), Dominican Republic
- Santo Domingo, Dominican Republic
- Cartagena, Colombia
- San Blas Islands, Panama
- Colon, Panama
- Balboa, Panama
- Panama Canal Transit
- ISLA PARIDA, PANAMA
- GOLFO DULCE, COSTA RICA
- Puerto Quepos, Costa Rica
- Puerto Caldera, Costa Rica
Ports
San Juan, Puerto Rico - Catalina Island (Isla Catalina), Dominican Republic - Santo Domingo, Dominican Republic - Cartagena, Colombia - San Blas Islands, Panama - Colon, Panama - Balboa, Panama - Panama Canal Transit - ISLA PARIDA, PANAMA - GOLFO DULCE, COSTA RICA - Puerto Quepos, Costa Rica - Puerto Caldera, Costa Rica - View more ports
Ports
- San Juan, Puerto Rico
- Catalina Island (Isla Catalina), Dominican Republic
- Santo Domingo, Dominican Republic
- Cartagena, Colombia
- San Blas Islands, Panama
- Colon, Panama
- Panama Canal Transit
- Balboa, Panama
- ISLA PARIDA, PANAMA
- GOLFO DULCE, COSTA RICA
- Puerto Quepos, Costa Rica
- Puerto Caldera, Costa Rica
- Curu (Reserve), Costa Rica
- Playas Del Coco, Costa Rica
- Puerto Chiapas (Tapachula), Mexico
- Huatulco, Mexico
- Manzanillo, Mexico
- Puerto Vallarta, Mexico
Ports
San Juan, Puerto Rico - Catalina Island (Isla Catalina), Dominican Republic - Santo Domingo, Dominican Republic - Cartagena, Colombia - San Blas Islands, Panama - Colon, Panama - Panama Canal Transit - Balboa, Panama - ISLA PARIDA, PANAMA - GOLFO DULCE, COSTA RICA - Puerto Quepos, Costa Rica - Puerto Caldera, Costa Rica - Curu (Reserve), Costa Rica - Playas Del Coco, Costa Rica - Puerto Chiapas (Tapachula), Mexico - Huatulco, Mexico - Manzanillo, Mexico - Puerto Vallarta, Mexico - View more ports
Ports
- GENOA (PORTOFINO), ITALY
- Marseille (Provence), France
- Barcelona, Spain
- Funchal, Madeira
- Philipsburg, St. Maarten
- CRUISE SOUTH ATLANTIC OCEAN
- Miami, Florida
- Cartagena, Colombia
- Colon, Panama
- Panama Canal Transit
- Puntarenas, Costa Rica
- Cabo San Lucas, Mexico
- San Diego, California
- San Pedro (Los Angeles), California
- Seattle, Washington
Ports
GENOA (PORTOFINO), ITALY - Marseille (Provence), France - Barcelona, Spain - Funchal, Madeira - Philipsburg, St. Maarten - CRUISE SOUTH ATLANTIC OCEAN - Miami, Florida - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Puntarenas, Costa Rica - Cabo San Lucas, Mexico - San Diego, California - San Pedro (Los Angeles), California - Seattle, Washington - View more ports
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
N/A |
$2934* |
$3774* |
N/A |
||
|
|
See Offers |
N/A |
$2949* |
$3789* |
N/A |
|
|
|
See Offers |
N/A |
$2949* |
$3789* |
N/A |
Ports
- Long Beach (Los Angeles), California
- Puerto Vallarta, Mexico
- Huatulco, Mexico
- Puerto Chiapas (Tapachula), Mexico
- Puerto Quetzal, Guatemala
- Puntarenas, Costa Rica
- Panama Canal Transit
- Cartagena, Colombia
- Miami, Florida
Ports
Long Beach (Los Angeles), California - Puerto Vallarta, Mexico - Huatulco, Mexico - Puerto Chiapas (Tapachula), Mexico - Puerto Quetzal, Guatemala - Puntarenas, Costa Rica - Panama Canal Transit - Cartagena, Colombia - Miami, Florida - View more ports
Ports
- Ft. Lauderdale (Port Everglades), Florida
- Cartagena, Colombia
- Panama Canal Transit
- PANAMA CITY (FUERTE AMADOR), PANAMA
- Puerto Caldera, Costa Rica
- Acajutla
- Puerto Quetzal, Guatemala
- Puerto Chiapas (Tapachula), Mexico
- Manzanillo, Mexico
- Puerto Vallarta, Mexico
- San Diego, California
Ports
Ft. Lauderdale (Port Everglades), Florida - Cartagena, Colombia - Panama Canal Transit - PANAMA CITY (FUERTE AMADOR), PANAMA - Puerto Caldera, Costa Rica - Acajutla - Puerto Quetzal, Guatemala - Puerto Chiapas (Tapachula), Mexico - Manzanillo, Mexico - Puerto Vallarta, Mexico - San Diego, California - View more ports
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
$2544* |
$3214* |
$3544* |
$9014* |
||
|
|
$2634* |
$3304* |
$3634* |
$9104* |
||
|
|
$2619* |
$3289* |
$3619* |
$4839* |
||
|
|
$2634* |
$3304* |
$3634* |
$9104* |
||
|
|
See Offers |
$2634* |
$3304* |
$3634* |
$4854* |
|
|
|
See Offers |
$2634* |
$3304* |
$3634* |
$4854* |
|
|
See Offers |
$2634* |
$3304* |
$3634* |
$4854* |
|
|
|
See Offers |
$2634* |
$3304* |
$3634* |
$4854* |
|
|
|
See Offers |
$2634* |
$3304* |
$3634* |
$9104* |
Ports
- Ft. Lauderdale (Port Everglades), Florida
- Cartagena, Colombia
- Panama Canal Transit
- PANAMA CITY (FUERTE AMADOR), PANAMA
- Puerto Caldera, Costa Rica
- Acajutla
- Puerto Quetzal, Guatemala
- Puerto Chiapas (Tapachula), Mexico
- Manzanillo, Mexico
- Puerto Vallarta, Mexico
- San Diego, California
- San Francisco, California
- Vancouver (Canada Place), British Columbia
Ports
Ft. Lauderdale (Port Everglades), Florida - Cartagena, Colombia - Panama Canal Transit - PANAMA CITY (FUERTE AMADOR), PANAMA - Puerto Caldera, Costa Rica - Acajutla - Puerto Quetzal, Guatemala - Puerto Chiapas (Tapachula), Mexico - Manzanillo, Mexico - Puerto Vallarta, Mexico - San Diego, California - San Francisco, California - Vancouver (Canada Place), British Columbia - View more ports
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
$2849* |
$3599* |
$3999* |
$5394* |
||
|
|
$2979* |
$3715* |
$4075* |
$5524* |
||
|
|
$2964* |
$3714* |
$4114* |
$5509* |
||
|
|
$2979* |
$3715* |
$4075* |
$5524* |
||
|
|
See Offers |
$2979* |
$3729* |
$4129* |
$5524* |
|
|
|
See Offers |
$2979* |
$3729* |
$4129* |
$5524* |
|
|
|
See Offers |
$2979* |
$3729* |
$4129* |
$5524* |
|
|
|
See Offers |
$2979* |
$3729* |
$4129* |
$5524* |
|
|
|
See Offers |
$2979* |
$3715* |
$4075* |
$5524* |
Ports
- Mobile, Alabama
- Cartagena, Colombia
- Panama Canal Transit
- Puntarenas, Costa Rica
- Cabo San Lucas, Mexico
- Seattle, Washington
Ports
Mobile, Alabama - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Cabo San Lucas, Mexico - Seattle, Washington - View more ports
Ports
- Ft. Lauderdale (Port Everglades), Florida
- Oranjestad, Aruba
- Panama Canal Transit
- PANAMA CITY (FUERTE AMADOR), PANAMA
- Mazatlan, Mexico
- Cabo San Lucas, Mexico
- San Pedro (Los Angeles), California
- Seattle, Washington
Ports
Ft. Lauderdale (Port Everglades), Florida - Oranjestad, Aruba - Panama Canal Transit - PANAMA CITY (FUERTE AMADOR), PANAMA - Mazatlan, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - Seattle, Washington - View more ports
20 Night Panama Canal - Ocean To Ocean (Ft. Lauderdale To Seatttle)
2026 sail dates:
Top positive review
Top critical review
| Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
|---|---|---|---|---|---|---|
|
|
$2157* |
$2757* |
N/A |
$12159* |
||
|
|
$2158* |
$2758* |
$3558* |
$4858* |
||
|
|
$2158* |
$2758* |
$3558* |
$4858* |
||
|
|
$2158* |
$2758* |
$3558* |
$4858* |
||
|
|
See Offers |
$2158* |
$2758* |
$3558* |
$4858* |
|
|
|
See Offers |
$2158* |
$2758* |
$3558* |
$4858* |
|
|
|
See Offers |
$2158* |
$2758* |
$3558* |
$4858* |
|
|
|
See Offers |
$2158* |
$2758* |
$3558* |
$4858* |
Ports
- Colon, Panama
- Panama Canal Transit
- Balboa, Panama
- ISLA PARIDA, PANAMA
- PUERTO JIMENEZ (GOLFO DULCE), COSTA RICA
- Puerto Quepos, Costa Rica
- Puerto Caldera, Costa Rica
- Curu (Reserve), Costa Rica
- Playas Del Coco, Costa Rica
- Puerto Chiapas (Tapachula), Mexico
- Huatulco, Mexico
- Manzanillo, Mexico
- Puerto Vallarta, Mexico
Ports
Colon, Panama - Panama Canal Transit - Balboa, Panama - ISLA PARIDA, PANAMA - PUERTO JIMENEZ (GOLFO DULCE), COSTA RICA - Puerto Quepos, Costa Rica - Puerto Caldera, Costa Rica - Curu (Reserve), Costa Rica - Playas Del Coco, Costa Rica - Puerto Chiapas (Tapachula), Mexico - Huatulco, Mexico - Manzanillo, Mexico - Puerto Vallarta, Mexico - View more ports
Ports
- Colon, Panama
- Panama Canal Transit
- Balboa, Panama
- ISLA PARIDA, PANAMA
- PUERTO JIMENEZ (GOLFO DULCE), COSTA RICA
- Puerto Quepos, Costa Rica
- Puerto Caldera, Costa Rica
Ports
Colon, Panama - Panama Canal Transit - Balboa, Panama - ISLA PARIDA, PANAMA - PUERTO JIMENEZ (GOLFO DULCE), COSTA RICA - Puerto Quepos, Costa Rica - Puerto Caldera, Costa Rica - View more ports
All prices are per person based on double occupancy and do not include port/government fees and gratuities.
More popular cruise lines sailing to Panama Canal, Central America
More popular departure ports with sailings to Panama Canal, Central America
- Ft. Lauderdale (Port Everglades), Florida Cruises to Panama Canal, Central America
- Miami, Florida Cruises to Panama Canal, Central America
- Tampa, Florida Cruises to Panama Canal, Central America
- Seattle, Washington Cruises to Panama Canal, Central America
- New York, New York Cruises to Panama Canal, Central America