Puerto Quetzal, Guatemala Cruises: Top Itineraries and Pricing

Ports

Ft. Lauderdale (Port Everglades), Florida
Half Moon Cay, Bahamas (Private Island)
Falmouth, Jamaica
Mahogany Bay, Roatan, Bay Islands, Honduras
Belize City, Belize
Cozumel, Mexico
Key West, Florida
Cartagena, Colombia
Panama Canal Transit
Puntarenas, Costa Rica
Puerto Quetzal, Guatemala
Huatulco, Mexico
Puerto Vallarta, Mexico
San Diego, California
San Francisco, California
Victoria, British Columbia
Vancouver (Canada Place), British Columbia

Ports

Ft. Lauderdale (Port Everglades), Florida - Half Moon Cay, Bahamas (Private Island) - Falmouth, Jamaica - Mahogany Bay, Roatan, Bay Islands, Honduras - Belize City, Belize - Cozumel, Mexico - Key West, Florida - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Huatulco, Mexico - Puerto Vallarta, Mexico - San Diego, California - San Francisco, California - Victoria, British Columbia - Vancouver (Canada Place), British Columbia - View more ports

30 Night Western Caribbean Explorer & Panama Canal (Ft. Lauderdale To Vancouver)

Eurodam L

4.1

(1100 Reviews)

2025 sail dates: Apr 02

$2899*

$97/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$2899*	$3319*	$5409*	$9829*
See Offers	$3119*	$3539*	$5629*	$10049*
	$3119*	$3539*	$5629*	$10049*
See Offers	$3119*	$3539*	$5629*	$10049*
See Offers	$3119*	$3539*	$5629*	$10049*
See Offers	$3119*	$3539*	$5629*	$10049*
See Offers	$3119*	$3539*	$5629*	$10049*
	$3119*	$3539*	$5604*	$10024*

Ports

San Diego, California
Cabo San Lucas, Mexico
Acapulco, Mexico
Puerto Quetzal, Guatemala
Panama City, Panama
Panama Canal Transit
Cartagena, Colombia
George Town, Grand Cayman
Miami, Florida

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Ports

San Diego, California - Cabo San Lucas, Mexico - Acapulco, Mexico - Puerto Quetzal, Guatemala - Panama City, Panama - Panama Canal Transit - Cartagena, Colombia - George Town, Grand Cayman - Miami, Florida - View more ports

14 Night Panama Canal: Mexico & Colombia (San Diego To Miami)

Norwegian Jade L

3.9

(1405 Reviews)

2025 sail dates: Oct 18

$2018*

$144/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$2018*	$2468*	$3618*	$4118*
See Offers	$2018*	$2468*	$3618*	$4118*
See Offers	$2018*	$2468*	$3618*	$4118*
See Offers	$2018*	$2468*	$3618*	$4118*

Ports

Miami, Florida
Cartagena, Colombia
Panama Canal Transit
Puntarenas, Costa Rica
Acajutla
Puerto Quetzal, Guatemala
Huatulco, Mexico
Puerto Vallarta, Mexico
Cabo San Lucas, Mexico
San Diego, California
Pichilingue (La Paz), Mexico
Loreto, Mexico
Guaymas, Mexico
Topolobampo, Mexico
Mazatlan, Mexico
Ensenada, Mexico

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Ports

Miami, Florida - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Acajutla - Puerto Quetzal, Guatemala - Huatulco, Mexico - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - San Diego, California - Pichilingue (La Paz), Mexico - Loreto, Mexico - Guaymas, Mexico - Topolobampo, Mexico - Mazatlan, Mexico - Ensenada, Mexico - View more ports

27 Night Panama Canal & Historic Sea Of Cortez (Miami To San Diego)

Zuiderdam M

4.0

(748 Reviews)

2026 sail dates: Jan 31

$3819*

$141/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$3819*	$4289*	$5509*	$8379*
See Offers	$3954*	$4424*	$5644*	$8514*
	$3954*	$4424*	$5644*	$8514*
See Offers	$3954*	$4424*	$5644*	$8514*
See Offers	$3954*	$4424*	$5644*	$8514*
See Offers	$3954*	$4424*	$5644*	$8514*
See Offers	$3954*	$4424*	$5644*	$8514*
	$3954*	$4424*	$5619*	$8489*

Ports

San Diego, California
Puerto Vallarta, Mexico
Huatulco, Mexico
Puerto Chiapas (Tapachula), Mexico
Puerto Quetzal, Guatemala
Fuerte Amador, Panama
Panama Canal Transit
Cartagena, Colombia
Half Moon Cay, Bahamas (Private Island)
Miami, Florida
Philipsburg, St. Maarten
St. John's, Antigua
Fort-De-France, Martinique
Roseau, Dominica
Basseterre, St. Kitts
Charlotte Amalie, St. Thomas

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Ports

San Diego, California - Puerto Vallarta, Mexico - Huatulco, Mexico - Puerto Chiapas (Tapachula), Mexico - Puerto Quetzal, Guatemala - Fuerte Amador, Panama - Panama Canal Transit - Cartagena, Colombia - Half Moon Cay, Bahamas (Private Island) - Miami, Florida - Philipsburg, St. Maarten - St. John's, Antigua - Fort-De-France, Martinique - Roseau, Dominica - Basseterre, St. Kitts - Charlotte Amalie, St. Thomas - View more ports

26 Night Panama Canal & Eastern Caribbean (San Diego To Miami)

Zuiderdam M

4.0

(748 Reviews)

2026 sail dates: Feb 27

$3509*

$135/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$3509*	$4169*	$5359*	$7719*
See Offers	$3729*	$4389*	$5579*	$7939*
	$3729*	$4389*	$5579*	$7939*
See Offers	$3729*	$4389*	$5579*	$7939*
See Offers	$3729*	$4389*	$5579*	$7939*
See Offers	$3729*	$4389*	$5579*	$7939*
See Offers	$3729*	$4389*	$5579*	$7939*
	$3729*	$4389*	$5554*	$7914*

Ports

San Francisco, California
Puerto Vallarta, Mexico
Puerto Quetzal, Guatemala
Puntarenas, Costa Rica
Fuerte Amador, Panama
Panama Canal Transit
Cartagena, Colombia
Ft. Lauderdale (Port Everglades), Florida

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Ports

San Francisco, California - Puerto Vallarta, Mexico - Puerto Quetzal, Guatemala - Puntarenas, Costa Rica - Fuerte Amador, Panama - Panama Canal Transit - Cartagena, Colombia - Ft. Lauderdale (Port Everglades), Florida - View more ports

16 Night Panama Canal - Ocean To Ocean (San Francisco To Fort Lauderdale)

Coral Princess M

4.1

(827 Reviews)

2025 sail dates: Jan 20

$1709*

$107/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1709*	$2008*	$2658*	N/A
See Offers	$1709*	$1854*	$2658*	$3308*
See Offers	$1709*	$1854*	$2658*	$3307*
	$1709*	$1854*	$2658*	$3308*
See Offers	$1709*	$1854*	$2658*	$3307*
See Offers	$1709*	$1854*	$2658*	$3307*
See Offers	$1709*	$1854*	$2658*	$3308*

Ports

Ft. Lauderdale (Port Everglades), Florida
Cartagena, Colombia
Panama Canal Transit
PANAMA CITY (FUERTE AMADOR), PANAMA
Puntarenas, Costa Rica
Puerto Quetzal, Guatemala
Puerto Vallarta, Mexico
San Francisco, California

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Ports

Ft. Lauderdale (Port Everglades), Florida - Cartagena, Colombia - Panama Canal Transit - PANAMA CITY (FUERTE AMADOR), PANAMA - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Puerto Vallarta, Mexico - San Francisco, California - View more ports

16 Night Panama Canal Ocean To Ocean (Ft. Lauderdale To San Francisco)

Coral Princess M

4.1

(827 Reviews)

2025 sail dates: Jan 04

$1299*

$81/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1299*	$1459*	$2459*	N/A
See Offers	$1299*	$1379*	$2459*	$3242*
See Offers	$1299*	$1379*	$2459*	$3242*
	$1299*	$1379*	$2459*	$3242*
See Offers	$1299*	$1379*	$2459*	$3242*
See Offers	$1299*	$1379*	$2459*	$3242*

Ports

Miami, Florida
George Town, Grand Cayman
Cartagena, Colombia
Panama Canal Transit
Puntarenas, Costa Rica
Puerto Corinto, Nicaragua
Puerto Quetzal, Guatemala
Acapulco, Mexico
Cabo San Lucas, Mexico
Ensenada, Mexico
San Pedro (Los Angeles), California

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Ports

Miami, Florida - George Town, Grand Cayman - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Corinto, Nicaragua - Puerto Quetzal, Guatemala - Acapulco, Mexico - Cabo San Lucas, Mexico - Ensenada, Mexico - San Pedro (Los Angeles), California - View more ports

16 Night Tropical Holiday (Miami To Los Angeles)

Seven Seas Grandeur M

4.1

(7 Reviews)

2024 sail dates: Dec 13

$10499*

$656/night*

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Partners	Bonus Offers	Inside	Oceanview	Balcony	Suite
		N/A	N/A	N/A	$10499*
		N/A	N/A	N/A	$10499*

Ports

Miami, Florida
Cartagena, Colombia
Panama Canal Transit
Puntarenas, Costa Rica
Puerto Quetzal, Guatemala
Zihuatanejo/Ixtapa, Mexico
Cabo San Lucas, Mexico
San Diego, California

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Ports

Miami, Florida - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Zihuatanejo/Ixtapa, Mexico - Cabo San Lucas, Mexico - San Diego, California - View more ports

17 Night Panama Canal Holiday Voyage (Miami To San Diego)

Azamara Onward S

4.3

(39 Reviews)

2024 sail dates: Dec 20

$7179*

$422/night*

Balcony

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Partners	Bonus Offers	Inside	Oceanview	Balcony	Suite
		N/A	N/A	$7179*	N/A
		N/A	N/A	$7179*	N/A

Ports

Auckland, New Zealand
Bay Of Islands, New Zealand
Noumea, New Caledonia
Mystery Island, Vanuatu
Port Vila, Efate, Vanuatu
Champagne Bay, Espiritu Santo, Vanuatu
Lautoka, Fiji Islands
Suva, Fiji
Pago Pago, American Samoa
Apia, Samoa
Cross International Dateline
Bora Bora, French Polynesia
Raiatea, French Polynesia
Papeete, Tahiti
Moorea, French Polynesia
Fakarava, Tuamotu Archipelago
Nuku Hiva, Marquesas
Honolulu, Oahu
Hilo, Hawaii
San Diego, California
Ensenada, Mexico
Cabo San Lucas, Mexico
Zihuatanejo/Ixtapa, Mexico
Puerto Quetzal, Guatemala
Puerto Corinto, Nicaragua
Puntarenas, Costa Rica
Panama Canal Transit
Cartagena, Colombia
George Town, Grand Cayman
Miami, Florida
Port Canaveral, Florida
New York, New York

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Ports

Auckland, New Zealand - Bay Of Islands, New Zealand - Noumea, New Caledonia - Mystery Island, Vanuatu - Port Vila, Efate, Vanuatu - Champagne Bay, Espiritu Santo, Vanuatu - Lautoka, Fiji Islands - Suva, Fiji - Pago Pago, American Samoa - Apia, Samoa - Cross International Dateline - Bora Bora, French Polynesia - Raiatea, French Polynesia - Papeete, Tahiti - Moorea, French Polynesia - Fakarava, Tuamotu Archipelago - Nuku Hiva, Marquesas - Honolulu, Oahu - Hilo, Hawaii - San Diego, California - Ensenada, Mexico - Cabo San Lucas, Mexico - Zihuatanejo/Ixtapa, Mexico - Puerto Quetzal, Guatemala - Puerto Corinto, Nicaragua - Puntarenas, Costa Rica - Panama Canal Transit - Cartagena, Colombia - George Town, Grand Cayman - Miami, Florida - Port Canaveral, Florida - New York, New York - View more ports

57 Night Epic Tropical Visits (Auckland To New York)

Insignia S

4.1

(88 Reviews)

2025 sail dates: May 28

$14499*

$254/night*

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Partners	Bonus Offers	Inside	Oceanview	Balcony	Suite
		$14499*	$15799*	$21299*	$26499*

Ports

San Francisco, California
San Pedro (Los Angeles), California
Ensenada, Mexico
Cabo San Lucas, Mexico
Acapulco, Mexico
Puerto Quetzal, Guatemala
Puerto Corinto, Nicaragua
Puntarenas, Costa Rica
Panama Canal Transit
Cartagena, Colombia
George Town, Grand Cayman
Miami, Florida

View more ports

Ports

San Francisco, California - San Pedro (Los Angeles), California - Ensenada, Mexico - Cabo San Lucas, Mexico - Acapulco, Mexico - Puerto Quetzal, Guatemala - Puerto Corinto, Nicaragua - Puntarenas, Costa Rica - Panama Canal Transit - Cartagena, Colombia - George Town, Grand Cayman - Miami, Florida - View more ports

18 Night West Coast Wonders (San Francisco To Miami)

Seven Seas Mariner S

3.9

(100 Reviews)

2025 sail dates: Jun 06

$9730*

$541/night*

Suite

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	N/A	N/A	N/A	$9730*
See Offers	N/A	N/A	N/A	$9730*
	N/A	N/A	N/A	$13399*
	N/A	N/A	N/A	$13399*
See Offers	N/A	N/A	N/A	$13130*

Puerto Quetzal, Guatemala cruises 139 Puerto Quetzal, Guatemala cruises

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