Colon, Panama cruises 225 Colon, Panama cruises

Your search Clear selections

Any Destination
All Sail Months
Any Length
Colon, Panama
Any Cruise Line
Any Ship

Close

225 cruises found

Sort by

Filter by

More

Ports

  • Ft. Lauderdale (Port Everglades), Florida
  • Cartagena, Colombia
  • Colon, Panama
  • Panama Canal (Cruise Into Canal)
  • Kralendijk, Bonaire
  • Oranjestad, Aruba
  • George Town, Grand Cayman
View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Kralendijk, Bonaire - Oranjestad, Aruba - George Town, Grand Cayman - View more ports

Ports

  • Valparaiso (Santiago), Chile
  • Iquique, Chile
  • Callao (Lima), Peru
  • Manta, Ecuador
  • Panama Canal Transit
  • Colon, Panama
  • Cozumel, Mexico
  • Ft. Lauderdale (Port Everglades), Florida
View more ports

Ports

Valparaiso (Santiago), Chile - Iquique, Chile - Callao (Lima), Peru - Manta, Ecuador - Panama Canal Transit - Colon, Panama - Cozumel, Mexico - Ft. Lauderdale (Port Everglades), Florida - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$9995*

$14995*

 

N/A

N/A

$9995*

$14995*

See Offers

N/A

N/A

$9995*

$14995*

Ports

  • Los Angeles, California
  • Cabo San Lucas, Mexico
  • CORINTO (LEON), NICARAGUA
  • Puerto Caldera, Costa Rica
  • Panama Canal Transit
  • Colon, Panama
  • Cartagena, Colombia
  • Cozumel, Mexico
  • Ft. Lauderdale (Port Everglades), Florida
View more ports

Ports

Los Angeles, California - Cabo San Lucas, Mexico - CORINTO (LEON), NICARAGUA - Puerto Caldera, Costa Rica - Panama Canal Transit - Colon, Panama - Cartagena, Colombia - Cozumel, Mexico - Ft. Lauderdale (Port Everglades), Florida - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$5999*

$11999*

 

N/A

N/A

$5999*

$11999*

See Offers

N/A

N/A

$5999*

$11999*

Ports

  • Tampa, Florida
  • George Town, Grand Cayman
  • Cartagena, Colombia
  • Colon, Panama
  • Panama Canal Transit
  • Puerto Quetzal, Guatemala
  • Puerto Vallarta, Mexico
  • Los Angeles, California
View more ports

Ports

Tampa, Florida - George Town, Grand Cayman - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Puerto Quetzal, Guatemala - Puerto Vallarta, Mexico - Los Angeles, California - View more ports

Ports

  • Colon, Panama
  • San Blas Islands, Panama
  • Panama Canal Transit
  • PLAYA MUERTO, DARIEN, PANAMA
  • Fuerte Amador, Panama
  • Puerto Quepos, Costa Rica
  • Puntarenas, Costa Rica
View more ports

Ports

Colon, Panama - San Blas Islands, Panama - Panama Canal Transit - PLAYA MUERTO, DARIEN, PANAMA - Fuerte Amador, Panama - Puerto Quepos, Costa Rica - Puntarenas, Costa Rica - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$18034*

 

N/A

N/A

$7454*

$12164*

See Offers

N/A

N/A

$7454*

$12164*

Ports

  • Ft. Lauderdale (Port Everglades), Florida
  • Cartagena, Colombia
  • Panama Canal (Cruise Into Canal)
  • Colon, Panama
  • Oranjestad, Aruba
  • Willemstad, Curacao
  • Kralendijk, Bonaire
View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Oranjestad, Aruba - Willemstad, Curacao - Kralendijk, Bonaire - View more ports

Ports

  • Colon, Panama
  • Panama Canal Transit
  • Balboa, Panama
  • ISLA PARIDA, PANAMA
  • PUERTO JIMENEZ (GOLFO DULCE), COSTA RICA
  • Puerto Quepos, Costa Rica
  • Puerto Caldera, Costa Rica
View more ports

Ports

Colon, Panama - Panama Canal Transit - Balboa, Panama - ISLA PARIDA, PANAMA - PUERTO JIMENEZ (GOLFO DULCE), COSTA RICA - Puerto Quepos, Costa Rica - Puerto Caldera, Costa Rica - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

$7469*

N/A

N/A

 

N/A

$4969*

N/A

N/A

See Offers

N/A

$4969*

N/A

N/A

Ports

  • Ft. Lauderdale (Port Everglades), Florida
  • Half Moon Cay, Bahamas (Private Island)
  • Oranjestad, Aruba
  • Cartagena, Colombia
  • Panama Canal (Cruise Into Canal)
  • Colon, Panama
  • Puerto Limon, Costa Rica
  • Montego Bay, Jamaica
  • Willemstad, Curacao
  • Kralendijk, Bonaire
View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Half Moon Cay, Bahamas (Private Island) - Oranjestad, Aruba - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - Montego Bay, Jamaica - Willemstad, Curacao - Kralendijk, Bonaire - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
See Offers

$2799*

N/A

N/A

N/A

See Offers

$2799*

N/A

N/A

N/A

See Offers

$2799*

N/A

N/A

N/A

Ports

  • Ft. Lauderdale (Port Everglades), Florida
  • Half Moon Cay, Bahamas (Private Island)
  • Oranjestad, Aruba
  • Cartagena, Colombia
  • Panama Canal (Cruise Into Canal)
  • Colon, Panama
  • Puerto Limon, Costa Rica
  • Montego Bay, Jamaica
View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Half Moon Cay, Bahamas (Private Island) - Oranjestad, Aruba - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - Montego Bay, Jamaica - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Ports

  • Ft. Lauderdale (Port Everglades), Florida
  • Cartagena, Colombia
  • Colon, Panama
  • Panama Canal (Cruise Into Canal)
  • Oranjestad, Aruba
  • Kralendijk, Bonaire
  • Willemstad, Curacao
View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Oranjestad, Aruba - Kralendijk, Bonaire - Willemstad, Curacao - View more ports

All prices are per person based on double occupancy and do not include port/government fees and gratuities.