Panama Canal, Central America Cruises : Best Cruise Prices

Ports

Ft. Lauderdale (Port Everglades), Florida
Oranjestad, Aruba
Kralendijk, Bonaire
Cartagena, Colombia
Colon, Panama
Panama Canal (Cruise Into Canal)
Puerto Limon, Costa Rica
George Town, Grand Cayman

Ports

Ft. Lauderdale (Port Everglades), Florida - Oranjestad, Aruba - Kralendijk, Bonaire - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports

12 Night Panama Canal With Costa Rica & Caribbean (Ft. Lauderdale Roundtrip)

Emerald Princess L

4.0

(1172 Reviews)

2025 sail dates: Jan 11, Jan 23

$847*

$71/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 1172 Emerald Princess reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$847*	$1397*	$1897*	$5078*
See Offers	$849*	$990*	$1899*	$2299*
See Offers	$848*	$989*	$1898*	$2298*
See Offers	$848*	$989*	$1898*	$2298*
See Offers	$848*	$989*	$1898*	$2298*
See Offers	$848*	$989*	$1898*	$2298*
	N/A	N/A	N/A	$2310*
See Offers	$848*	$989*	$1898*	$2298*
See Offers	$848*	$989*	$1898*	$2298*
See Offers	$848*	$989*	$1898*	$2298*
	$848*	$989*	$1898*	$2298*
	$847*	$1397*	$1797*	$4817*
See Offers	$849*	$977*	$1799*	$2399*
See Offers	$848*	$976*	$1798*	$2398*
See Offers	$848*	$976*	$1798*	$2398*
See Offers	$848*	$976*	$1798*	$2398*
	N/A	N/A	N/A	$2001*
See Offers	$848*	$976*	$1798*	$1989*
See Offers	$848*	$976*	$1798*	$1989*
See Offers	$848*	$976*	$1798*	$1989*
	$848*	$976*	$1798*	$2398*

Ports

Ft. Lauderdale (Port Everglades), Florida
Kralendijk, Bonaire
Oranjestad, Aruba
Cartagena, Colombia
Colon, Panama
Panama Canal (Cruise Into Canal)
Puerto Limon, Costa Rica
George Town, Grand Cayman

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Kralendijk, Bonaire - Oranjestad, Aruba - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports

12 Night Panama Canal With Costa Rica & Caribbean (Ft. Lauderdale Roundtrip)

Emerald Princess L

4.0

(1172 Reviews)

2024 sail dates: Dec 06

2025 sail dates: Feb 28

$597*

$50/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 1172 Emerald Princess reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$597*	$979*	$1297*	$3698*
See Offers	$598*	$698*	$1298*	$1798*
See Offers	$598*	$698*	$1298*	$1798*
See Offers	$598*	$698*	$1298*	$1798*
See Offers	$598*	$698*	$1298*	$1798*
	N/A	N/A	N/A	$1810*
See Offers	$598*	$698*	$1298*	$1798*
See Offers	$538*	$628*	$1168*	$1618*
See Offers	$538*	$628*	$1168*	$1618*
	$598*	$698*	$1298*	$1798*
	$697*	$1097*	$1547*	$4696*
See Offers	$698*	$803*	$1548*	$2098*
See Offers	$698*	$803*	$1548*	$2098*
See Offers	$698*	$803*	$1548*	$2098*
See Offers	$698*	$803*	$1548*	$2098*
	N/A	N/A	N/A	$2110*
See Offers	$698*	$803*	$1548*	$2098*
See Offers	$628*	$722*	$1393*	$1888*
See Offers	$628*	$722*	$1393*	$1888*
	$698*	$803*	$1548*	$2098*

Ports

Ft. Lauderdale (Port Everglades), Florida
Cartagena, Colombia
Panama Canal Transit
Puntarenas, Costa Rica
Puerto Quetzal, Guatemala
Puerto Vallarta, Mexico
San Pedro (Los Angeles), California

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Puerto Vallarta, Mexico - San Pedro (Los Angeles), California - View more ports

15 Night World Voyage Segment - Panama Canal Connoisseur (Ft. Lauderdale To Los Angeles)

Island Princess M

4.0

(894 Reviews)

2025 sail dates: Jan 05

$1217*

$81/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 894 Island Princess reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1217*	$1697*	$2127*	N/A
See Offers	$1219*	$1313*	$2082*	$2806*
See Offers	$1218*	$1312*	$2128*	$2805*
See Offers	$1218*	$1312*	$2128*	$2805*
See Offers	$1218*	$1312*	$2128*	$2805*
See Offers	$1218*	$1312*	$2081*	$2805*
	N/A	N/A	N/A	$2817*
See Offers	$1218*	$1312*	$2081*	$2805*
See Offers	$1218*	$1312*	$2081*	$2805*
See Offers	$1218*	$1312*	$2081*	$2805*
	$1218*	$1312*	$2128*	$2805*

Ports

Ft. Lauderdale (Port Everglades), Florida
Oranjestad, Aruba
Willemstad, Curacao
Cartagena, Colombia
Colon, Panama
Panama Canal (Cruise Into Canal)
Puerto Limon, Costa Rica
Ocho Rios, Jamaica

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Oranjestad, Aruba - Willemstad, Curacao - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - Ocho Rios, Jamaica - View more ports

12 Night Panama Canal With Costa Rica & Caribbean (Ft. Lauderdale Roundtrip)

Emerald Princess L

4.0

(1172 Reviews)

2024 sail dates: Dec 30

$697*

$58/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 1172 Emerald Princess reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$697*	$997*	$1397*	$4682*
See Offers	$698*	$793*	$1398*	$2348*
See Offers	$698*	$793*	$1398*	$2348*
See Offers	$698*	$793*	$1398*	$2348*
See Offers	$698*	$793*	$1398*	$2309*
	N/A	N/A	N/A	$2321*
See Offers	$698*	$793*	$1398*	$2309*
See Offers	$698*	$793*	$1398*	$2348*
See Offers	$698*	$793*	$1398*	$2348*
	$698*	$793*	$1398*	$2348*

Ports

Ft. Lauderdale (Port Everglades), Florida
Oranjestad, Aruba
Willemstad, Curacao
Cartagena, Colombia
Panama Canal (Cruise Into Canal)
Cristobal, Panama
Puerto Limon, Costa Rica
George Town, Grand Cayman

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Oranjestad, Aruba - Willemstad, Curacao - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Cristobal, Panama - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports

12 Night Panama Canal With Costa Rica & Caribbean (Ft. Lauderdale Roundtrip)

Emerald Princess L

4.0

(1172 Reviews)

2025 sail dates: Feb 04

$747*

$62/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 1172 Emerald Princess reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$747*	$1277*	$1747*	$4817*
See Offers	$749*	$861*	$1749*	$2299*
See Offers	$748*	$860*	$1748*	$2298*
See Offers	$748*	$860*	$1748*	$2298*
See Offers	$748*	$860*	$1748*	$2298*
See Offers	$674*	$774*	$1574*	$2069*
	N/A	N/A	N/A	$2081*
See Offers	$748*	$860*	$1748*	$2298*
See Offers	$674*	$774*	$1574*	$2069*
See Offers	$674*	$774*	$1574*	$2069*
	$748*	$860*	$1748*	$2298*

Ports

Ft. Lauderdale (Port Everglades), Florida
Kralendijk, Bonaire
Oranjestad, Aruba
Cartagena, Colombia
Panama Canal (Cruise Into Canal)
Colon, Panama
Puerto Limon, Costa Rica
Ocho Rios, Jamaica

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Kralendijk, Bonaire - Oranjestad, Aruba - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - Ocho Rios, Jamaica - View more ports

12 Night Panama Canal With Costa Rica & Caribbean (Ft. Lauderdale Roundtrip)

Emerald Princess L

4.0

(1172 Reviews)

2025 sail dates: Feb 16

$827*

$69/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 1172 Emerald Princess reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$827*	$1447*	$2027*	$4686*
See Offers	$829*	$954*	$1999*	$2499*
See Offers	$828*	$953*	$2028*	$2798*
See Offers	$828*	$953*	$2028*	$2798*
See Offers	$828*	$953*	$2028*	$2798*
See Offers	$828*	$953*	$2028*	$2798*
	N/A	N/A	N/A	$2810*
See Offers	$828*	$953*	$2028*	$2798*
See Offers	$828*	$953*	$2028*	$2798*
See Offers	$828*	$953*	$2028*	$2798*
	$828*	$953*	$2028*	$2798*

Ports

San Pedro (Los Angeles), California
Puerto Vallarta, Mexico
Huatulco, Mexico
San Juan Del Sur, Nicaragua
Puntarenas, Costa Rica
PANAMA CITY (FUERTE AMADOR), PANAMA
Panama Canal Transit
Oranjestad, Aruba
Ft. Lauderdale (Port Everglades), Florida

View more ports

Ports

San Pedro (Los Angeles), California - Puerto Vallarta, Mexico - Huatulco, Mexico - San Juan Del Sur, Nicaragua - Puntarenas, Costa Rica - PANAMA CITY (FUERTE AMADOR), PANAMA - Panama Canal Transit - Oranjestad, Aruba - Ft. Lauderdale (Port Everglades), Florida - View more ports

16 Night Panama Canal - Ocean To Ocean (Los Angeles To Ft. Lauderdale)

Coral Princess M

4.1

(825 Reviews)

2025 sail dates: Feb 21, Mar 25

$1097*

$69/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 825 Coral Princess reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1227*	$1427*	$2297*	N/A
See Offers	$1229*	$1405*	$2251*	$2833*
See Offers	$1228*	$1404*	$2250*	$2832*
See Offers	$1228*	$1404*	$2250*	$2832*
See Offers	$1228*	$1404*	$2250*	$2832*
See Offers	$1228*	$1404*	$2250*	$2832*
	N/A	N/A	N/A	$2844*
See Offers	$1228*	$1404*	$2250*	$2832*
See Offers	$1228*	$1404*	$2250*	$2832*
See Offers	$1228*	$1404*	$2250*	$2832*
	$1228*	$1404*	$2250*	$2832*
	$1097*	$1347*	$1847*	$5198*
See Offers	$1099*	$1256*	$1810*	$2514*
See Offers	$1098*	$1255*	$1809*	$2513*
See Offers	$1098*	$1255*	$1809*	$2513*
See Offers	$1098*	$1255*	$1809*	$2513*
	N/A	N/A	N/A	$2525*
See Offers	$1098*	$1255*	$1809*	$2513*
See Offers	$1098*	$1255*	$1809*	$2513*
See Offers	$1098*	$1255*	$1809*	$2513*
	$1098*	$1255*	$1809*	$2513*

Ports

Ft. Lauderdale (Port Everglades), Florida
George Town, Grand Cayman
Puerto Limon, Costa Rica
Panama Canal (Cruise Into Canal)
Colon, Panama
Oranjestad, Aruba
Willemstad, Curacao

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - George Town, Grand Cayman - Puerto Limon, Costa Rica - Panama Canal (Cruise Into Canal) - Colon, Panama - Oranjestad, Aruba - Willemstad, Curacao - View more ports

12 Night Panama Canal With Costa Rica & Caribbean (Ft. Lauderdale Roundtrip)

Emerald Princess L

4.0

(1172 Reviews)

2024 sail dates: Dec 18

$647*

$54/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 1172 Emerald Princess reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$647*	$927*	$1327*	$4448*
See Offers	$648*	$736*	$1328*	$2398*
See Offers	$648*	$736*	$1328*	$2398*
See Offers	$648*	$736*	$1328*	$2398*
See Offers	$648*	$736*	$1328*	$2284*
See Offers	$648*	$736*	$1328*	$2398*
See Offers	$648*	$736*	$1328*	$2398*
	$648*	$736*	$1328*	$2398*

Ports

Ft. Lauderdale (Port Everglades), Florida
Oranjestad, Aruba
Panama Canal Transit
Fuerte Amador, Panama
Puntarenas, Costa Rica
San Juan Del Sur, Nicaragua
Huatulco, Mexico
Puerto Vallarta, Mexico
San Pedro (Los Angeles), California

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Oranjestad, Aruba - Panama Canal Transit - Fuerte Amador, Panama - Puntarenas, Costa Rica - San Juan Del Sur, Nicaragua - Huatulco, Mexico - Puerto Vallarta, Mexico - San Pedro (Los Angeles), California - View more ports

16 Night Panama Canal - Ocean To Ocean (Ft. Lauderdale To Los Angeles)

Coral Princess M

4.1

(825 Reviews)

2025 sail dates: Feb 05, Mar 09

$1127*

$70/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 825 Coral Princess reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1217*	$1477*	$2347*	N/A
See Offers	$1219*	$1394*	$2300*	$2623*
See Offers	$1218*	$1393*	$2299*	$2622*
See Offers	$1218*	$1393*	$2299*	$2622*
See Offers	$1218*	$1393*	$2299*	$2622*
See Offers	$1218*	$1393*	$2299*	$2622*
	N/A	N/A	N/A	$2634*
See Offers	$1218*	$1393*	$2299*	$2622*
See Offers	$1218*	$1393*	$2299*	$2622*
See Offers	$1218*	$1393*	$2299*	$2622*
	$1218*	$1393*	$2299*	$2622*
	$1127*	$1397*	$1827*	N/A
See Offers	$1129*	$1290*	$1791*	$2598*
See Offers	$1128*	$1289*	$1790*	$2597*
See Offers	$1128*	$1289*	$1790*	$2597*
See Offers	$1128*	$1289*	$1790*	$2597*
See Offers	$1128*	$1289*	$1790*	$2597*
	N/A	N/A	N/A	$2609*
See Offers	$1128*	$1289*	$1790*	$2597*
See Offers	$1128*	$1289*	$1790*	$2597*
See Offers	$1128*	$1289*	$1790*	$2597*
	$1128*	$1289*	$1790*	$2597*

Ports

Ft. Lauderdale (Port Everglades), Florida
Oranjestad, Aruba
Willemstad, Curacao
Cartagena, Colombia
Colon, Panama
Panama Canal (Cruise Into Canal)
Puerto Limon, Costa Rica
George Town, Grand Cayman

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Oranjestad, Aruba - Willemstad, Curacao - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports

12 Night Panama Canal With Costa Rica & Caribbean (Ft. Lauderdale Roundtrip)

Emerald Princess L

4.0

(1172 Reviews)

2024 sail dates: Oct 31, Nov 12, Nov 24

2025 sail dates: Mar 12

$827*

$69/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 1172 Emerald Princess reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$797*	$1450*	$1947*	N/A
See Offers	$799*	$919*	$1949*	$3124*
See Offers	$798*	$918*	$1948*	$5058*
See Offers	$798*	$918*	$1948*	$5058*
See Offers	$798*	$918*	$1948*	$5058*
See Offers	$798*	$918*	$1948*	$2088*
	N/A	N/A	N/A	$2100*
See Offers	$798*	$918*	$1948*	$2088*
See Offers	$798*	$918*	$1948*	$2088*
See Offers	$798*	$918*	$1948*	$2088*
	$798*	$918*	$1948*	$5058*
	$697*	$1124*	$1447*	$4957*
See Offers	$698*	$911*	$1448*	$1848*
See Offers	$698*	$911*	$1448*	$1848*
See Offers	$698*	$911*	$1448*	$1848*
	N/A	N/A	N/A	$1859*
See Offers	$698*	$911*	$1448*	$2065*
See Offers	$698*	$911*	$1448*	$2065*
See Offers	$698*	$911*	$1448*	$2065*
	$698*	$911*	$1448*	$1848*
	$597*	$917*	$1397*	$3598*
See Offers	$598*	$766*	$1398*	$1798*
See Offers	$598*	$766*	$1398*	$1798*
See Offers	$598*	$766*	$1398*	$1798*
See Offers	$598*	$766*	$1398*	$1798*
See Offers	$598*	$766*	$1398*	$1798*
See Offers	$598*	$766*	$1398*	$1798*
	$598*	$766*	$1398*	$1798*
	$827*	$1297*	$1847*	$4269*
See Offers	$829*	$953*	$1849*	$2249*
See Offers	$828*	$952*	$1848*	$2248*
See Offers	$828*	$952*	$1848*	$2248*
See Offers	$828*	$952*	$1848*	$2248*
See Offers	$828*	$952*	$1848*	$2039*
	N/A	N/A	N/A	$2051*
See Offers	$828*	$952*	$1848*	$2039*
See Offers	$828*	$952*	$1848*	$2039*
See Offers	$828*	$952*	$1848*	$2039*
	$828*	$952*	$1848*	$2248*

Panama Canal, Central America cruises 15 Panama Canal, Central America Cruises Found

Your search Clear selections

15 cruises found

Sort by

Filter by

More popular cruise lines sailing to Panama Canal, Central America

More popular departure ports with sailings to Panama Canal, Central America