Panama Canal, Central America cruises 152 Panama Canal, Central America Cruises Found

Your search Clear selections

Panama Canal, Central America

All Sail Months

Any Length

Any Port

Any Cruise Line

Any Ship

152 cruises found

Filters Save search

Sponsored cruise

Ports

Miami, Florida
George Town, Grand Cayman
Cartagena, Colombia
Colon, Panama
Panama Canal (Cruise Into Canal)
Puerto Limon, Costa Rica
Harvest Caye, Belize
Cozumel, Mexico

View more ports

Ports

Miami, Florida - George Town, Grand Cayman - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - Harvest Caye, Belize - Cozumel, Mexico - View more ports

11 Night Panama Canal: Mexico Costa Rica & Belize (Miami Roundtrip)

Norwegian Gem L

3.8

(2493 Reviews)

2024 sail dates:

2025 sail dates: Jan 03

$1091*

$99/night*

Inside

View Deal

Loading itinerary...

Loading reviews...

Read all 2493 Norwegian Gem reviews

Ports

Ft. Lauderdale (Port Everglades), Florida
Half Moon Cay, Bahamas (Private Island)
Willemstad, Curacao
Cartagena, Colombia
Colon, Panama
Panama Canal (Cruise Into Canal)
Puerto Limon, Costa Rica
George Town, Grand Cayman

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Half Moon Cay, Bahamas (Private Island) - Willemstad, Curacao - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports

12 Night Panama Canal Discovery: Costa Rica & Greater Antilles (Ft. Lauderdale Roundtrip)

Rotterdam L

4.4

(254 Reviews)

2025 sail dates: Oct 26, Dec 07

2026 sail dates: Feb 08, Mar 01

$1374*

$115/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 254 Rotterdam reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1469*	$2019*	$2169*	$3519*
See Offers	$1614*	$2164*	$2314*	$3664*
	$1614*	$2164*	$2314*	$3664*
See Offers	$1614*	$2164*	$2314*	$3664*
See Offers	$1614*	$2164*	$2314*	$3664*
See Offers	$1614*	$2164*	$2314*	$3664*
See Offers	$1614*	$2164*	$2314*	$3664*
	$1374*	$1924*	$2074*	$3424*
See Offers	$1519*	$2069*	$2219*	$3569*
	$1519*	$2069*	$2219*	$3569*
See Offers	$1519*	$2069*	$2219*	$3569*
See Offers	$1519*	$2069*	$2219*	$3569*
See Offers	$1519*	$2069*	$2219*	$3569*
See Offers	$1519*	$2069*	$2219*	$3569*
	$1764*	$2314*	$2464*	$3864*
See Offers	$1909*	$2459*	$2609*	$4009*
	$1909*	$2459*	$2609*	$4009*
See Offers	$1909*	$2459*	$2609*	$4009*
See Offers	$1909*	$2459*	$2609*	$4009*
See Offers	$1909*	$2459*	$2609*	$4009*
See Offers	$1909*	$2459*	$2609*	$4009*
	$1654*	$2204*	$2354*	$3964*
See Offers	$1799*	$2349*	$2499*	$3959*
	$1799*	$2349*	$2499*	$3959*
See Offers	$1799*	$2349*	$2499*	$3959*
See Offers	$1799*	$2349*	$2499*	$4109*
See Offers	$1799*	$2349*	$2499*	$4109*
See Offers	$1799*	$2349*	$2499*	$4109*

Ports

Ft. Lauderdale (Port Everglades), Florida
Willemstad, Curacao
Kralendijk, Bonaire
Oranjestad, Aruba
Half Moon Cay, Bahamas (Private Island)
Cartagena, Colombia
Colon, Panama
Panama Canal (Cruise Into Canal)
Puerto Limon, Costa Rica
George Town, Grand Cayman

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Willemstad, Curacao - Kralendijk, Bonaire - Oranjestad, Aruba - Half Moon Cay, Bahamas (Private Island) - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports

21 Night Southern Caribbean & Panama Canal: Abc Islands (Ft. Lauderdale Roundtrip)

Rotterdam L

4.4

(254 Reviews)

2026 sail dates: Jan 30, Feb 20

$2544*

$121/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 254 Rotterdam reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$2554*	$3274*	$3614*	$5444*
See Offers	$2799*	$3519*	$3859*	$5689*
	$2799*	$3519*	$3859*	$5689*
See Offers	$2799*	$3519*	$3859*	$5689*
See Offers	$2799*	$3519*	$3859*	$5689*
See Offers	$2799*	$3519*	$3859*	$5689*
See Offers	$2799*	$3519*	$3859*	$5689*
	$2544*	$3264*	$3564*	$5434*
See Offers	$2789*	$3509*	$3809*	$5679*
	$2789*	$3509*	$3809*	$5679*
See Offers	$2789*	$3509*	$3809*	$5679*
See Offers	$2789*	$3509*	$3809*	$5679*
See Offers	$2789*	$3509*	$3809*	$5679*
See Offers	$2789*	$3509*	$3809*	$5679*

151 - 152 of 152

All prices are per person based on double occupancy and do not include port/government fees and gratuities.

Panama Canal, Central America cruises 152 Panama Canal, Central America Cruises Found

Your search Clear selections

152 cruises found

Sort by

Filter by

More popular cruise lines sailing to Panama Canal, Central America

More popular departure ports with sailings to Panama Canal, Central America