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American Cruise Line Cruises to River Cruises - United States 125 cruises on American Cruise Line found

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125 cruises found

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Ports

  • Memphis, Tennessee
  • RIVER CRUISING
  • Vicksburg, Mississippi
  • Natchez, Mississippi
  • St. Francisville, Louisiana
  • Baton Rouge, Louisiana
  • Houmas House Plantation, Louisiana
  • New Orleans, Louisiana
View more ports

Ports

Memphis, Tennessee - RIVER CRUISING - Vicksburg, Mississippi - Natchez, Mississippi - St. Francisville, Louisiana - Baton Rouge, Louisiana - Houmas House Plantation, Louisiana - New Orleans, Louisiana - View more ports

American Symphony S

4.2
(4 Reviews)

2024 sail dates: Dec 30

2025 sail dates: Jul 16, Aug 27, Nov 05, More

$4415*
$631/night*
Balcony
View Deal
$4415* luxuryonly.com $4415* dreamvacations.com
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Read all 4 American Symphony reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

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$5275*

$7295*

 

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$5995*

$8290*

 

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Ports

  • Memphis, Tennessee
  • RIVER CRUISING
  • Paducah, Kentucky
  • Dover, Tennessee
  • CLARKSVILLE, TENNESSEE
  • Nashville, Tennessee
View more ports

Ports

Memphis, Tennessee - RIVER CRUISING - Paducah, Kentucky - Dover, Tennessee - CLARKSVILLE, TENNESSEE - Nashville, Tennessee - View more ports

American Symphony S

4.2
(4 Reviews)

2025 sail dates: Apr 23, Sep 10

$4915*
$702/night*
Balcony
View Deal
$4915* luxuryonly.com $4915* dreamvacations.com
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Top positive review

Top critical review

Read all 4 American Symphony reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$5275*

$7295*

 

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N/A

$5275*

$7295*

See Offers

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$4915*

$6800*

 

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$4915*

$6800*

 

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$5275*

$7295*

 

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$5275*

$7295*

Ports

  • Nashville, Tennessee
  • CLARKSVILLE, TENNESSEE
  • Paducah, Kentucky
  • Savannah, Tennessee
  • Florence, Alabama
  • Decatur, Alabama
  • Chattanooga, Tennessee
View more ports

Ports

Nashville, Tennessee - CLARKSVILLE, TENNESSEE - Paducah, Kentucky - Savannah, Tennessee - Florence, Alabama - Decatur, Alabama - Chattanooga, Tennessee - View more ports

American Symphony S

4.2
(4 Reviews)

2025 sail dates: Apr 30, May 14, May 28, Jun 11, Sep 17, Oct 01, Oct 15, More

$4415*
$631/night*
Balcony
View Deal
$4415* luxuryonly.com $4415* dreamvacations.com
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Top positive review

Top critical review

Read all 4 American Symphony reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

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$5275*

$7295*

 

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$5275*

$7295*

 

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$4775*

$6795*

 

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$4775*

$6795*

 

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$4775*

$6795*

 

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$4775*

$6795*

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$6795*

 

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$6795*

 

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$4415*

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Ports

  • Baltimore, Maryland
  • Yorktown, Virginia
  • CRISFIELD, MARYLAND
  • CAMBRIDGE, MARYLAND
  • ST. MICHAELS, MARYLAND
  • ANNAPOLIS, MARYLAND
View more ports

Ports

Baltimore, Maryland - Yorktown, Virginia - CRISFIELD, MARYLAND - CAMBRIDGE, MARYLAND - ST. MICHAELS, MARYLAND - ANNAPOLIS, MARYLAND - View more ports

American Independence S

4.6
(8 Reviews)

2025 sail dates: May 03, May 17

2026 sail dates: May 02, May 09, May 16

$4610*
$659/night*
Oceanview
View Deal
$4610* luxuryonly.com $4610* dreamvacations.com
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Read all 8 American Independence reviews

Ports

  • Portland, Oregon
  • HAYDEN ISLAND, PORTLAND, OREGON
  • Astoria, Oregon
  • Mount St. Helens, Washington
  • Cruise Columbia River
  • THE DALLES, OREGON
  • Pendleton, Oregon
  • CRUISE SNAKE RIVER, PACIFIC NORTHWEST, USA
  • Clarkston, Washington
View more ports

Ports

Portland, Oregon - HAYDEN ISLAND, PORTLAND, OREGON - Astoria, Oregon - Mount St. Helens, Washington - Cruise Columbia River - THE DALLES, OREGON - Pendleton, Oregon - CRUISE SNAKE RIVER, PACIFIC NORTHWEST, USA - Clarkston, Washington - View more ports

American West S

5.0
(1 Reviews)

2025 sail dates: May 05, Jun 02, Jun 16, Jun 30, Jul 14, Jul 28, Aug 11, Aug 25, Sep 08, Sep 22, Oct 06 More

$4925*
$704/night*
Oceanview
View Deal
$4925* luxuryonly.com $4925* dreamvacations.com
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Ports

  • Chattanooga, Tennessee
  • Decatur, Alabama
  • Florence, Alabama
  • Savannah, Tennessee
  • Paducah, Kentucky
  • CLARKSVILLE, TENNESSEE
  • Nashville, Tennessee
View more ports

Ports

Chattanooga, Tennessee - Decatur, Alabama - Florence, Alabama - Savannah, Tennessee - Paducah, Kentucky - CLARKSVILLE, TENNESSEE - Nashville, Tennessee - View more ports

American Symphony S

4.2
(4 Reviews)

2025 sail dates: May 07, May 21, Jun 18, Jul 30, Sep 24, Oct 08, Oct 22, More

$4775*
$682/night*
Balcony
View Deal
$4775* luxuryonly.com $4775* dreamvacations.com
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Top positive review

Top critical review

Read all 4 American Symphony reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

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$5275*

$7295*

 

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$5275*

$7295*

 

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$6795*

 

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$6795*

 

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$6795*

 

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$4775*

$6795*

 

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$4915*

$6800*

 

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$4915*

$6800*

See Offers

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$5275*

$7295*

 

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$5275*

$7295*

See Offers

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$7295*

 

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$7295*

 

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Ports

  • Baltimore, Maryland
  • Yorktown, Virginia
  • CRISFIELD, MARYLAND
  • CAMBRIDGE, MARYLAND
  • ST. MICHAELS, MARYLAND
  • ANNAPOLIS, MARYLAND
View more ports

Ports

Baltimore, Maryland - Yorktown, Virginia - CRISFIELD, MARYLAND - CAMBRIDGE, MARYLAND - ST. MICHAELS, MARYLAND - ANNAPOLIS, MARYLAND - View more ports

American Star S

4.5
(9 Reviews)

2025 sail dates:

$4610*
$659/night*
Oceanview
View Deal
$4610* luxuryonly.com $4610* dreamvacations.com
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Loading reviews...

Top positive review

Top critical review

Read all 9 American Star reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

$4610*

$5490*

$7295*

 

N/A

$4610*

$5490*

$7295*

Ports

  • Seattle, Washington
  • ANACORTES, WASHINGTON
  • FRIDAY HARBOR, SAN JUAN ISLAND, WASHINGTON
  • Cruise Inside Passage, Alaska
  • Ketchikan, Alaska
  • Wrangell, Alaska
  • PETERSBURG, ALASKA
  • Cruise Tracy Arm Fjord, Alaska
  • Cruise Glacier Bay
  • Haines, Alaska
  • Skagway, Alaska
  • Juneau, Alaska
View more ports

Ports

Seattle, Washington - ANACORTES, WASHINGTON - FRIDAY HARBOR, SAN JUAN ISLAND, WASHINGTON - Cruise Inside Passage, Alaska - Ketchikan, Alaska - Wrangell, Alaska - PETERSBURG, ALASKA - Cruise Tracy Arm Fjord, Alaska - Cruise Glacier Bay - Haines, Alaska - Skagway, Alaska - Juneau, Alaska - View more ports

American Constitution XL

5.0
(4 Reviews)

2025 sail dates: Sep 07

2026 sail dates: May 09

$9810*
$701/night*
Oceanview
View Deal
$9810* luxuryonly.com $9810* dreamvacations.com
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Top critical review

Read all 4 American Constitution reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

$9810*

$11435*

$15380*

 

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$9810*

$11435*

$15380*

 

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$10310*

$11935*

$15880*

 

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$10310*

$11935*

$15880*

See Offers

N/A

$10810*

$12435*

$16380*

 

N/A

$10810*

$12435*

$16380*

Ports

  • Seattle, Washington
  • ANACORTES, WASHINGTON
  • FRIDAY HARBOR, SAN JUAN ISLAND, WASHINGTON
  • Victoria, British Columbia
  • PORT TOWNSEND, WASHINGTON
  • POULSBO, WA
View more ports

Ports

Seattle, Washington - ANACORTES, WASHINGTON - FRIDAY HARBOR, SAN JUAN ISLAND, WASHINGTON - Victoria, British Columbia - PORT TOWNSEND, WASHINGTON - POULSBO, WA - View more ports

American Spirit S

4.7
(11 Reviews)

2025 sail dates:

$4925*
$704/night*
Oceanview
View Deal
$4925* luxuryonly.com $4925* dreamvacations.com
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Top positive review

Top critical review

Read all 11 American Spirit reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

$4925*

$5865*

$7795*

 

N/A

$4925*

$5865*

$7795*

Ports

  • Clarkston, Washington
  • CRUISE SNAKE RIVER, PACIFIC NORTHWEST, USA
  • Pendleton, Oregon
  • THE DALLES, OREGON
  • Cruise Columbia River
  • Mount St. Helens, Washington
  • Astoria, Oregon
  • Portland, Oregon
View more ports

Ports

Clarkston, Washington - CRUISE SNAKE RIVER, PACIFIC NORTHWEST, USA - Pendleton, Oregon - THE DALLES, OREGON - Cruise Columbia River - Mount St. Helens, Washington - Astoria, Oregon - Portland, Oregon - View more ports

American West S

5.0
(1 Reviews)

2025 sail dates: May 12, Jun 09, Jun 23, Jul 07, Jul 21, Aug 04, Aug 18, Sep 01, Sep 15, Sep 29, Oct 13 More

$4925*
$704/night*
Oceanview
View Deal
$4925* luxuryonly.com $4925* dreamvacations.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

31 - 40 of 125

All prices are per person based on double occupancy and do not include port/government fees and gratuities.

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