1. Home
  2. Find a cruise
  3. Palermo, Sicily cruises

Palermo, Sicily cruises 156 Palermo, Sicily cruises

Your search Clear selections

Any Destination
All Sail Months
Any Length
Palermo, Sicily
Any Cruise Line
Any Ship

Close

156 cruises found

Filters Save search

Sort by

Filter by

More
Save search

Ports

  • FUSINA (VENICE), ITALY
  • Zadar, Croatia
  • Hvar, Croatia
  • Dubrovnik, Croatia
  • Bari, Italy
  • Kotor, Montenegro
  • Valletta, Malta
  • Giardini Di Naxos (Taormina), Sicily
  • Palermo, Sicily
  • Naples, Italy
  • Civitavecchia (Rome), Italy
View more ports

Ports

FUSINA (VENICE), ITALY - Zadar, Croatia - Hvar, Croatia - Dubrovnik, Croatia - Bari, Italy - Kotor, Montenegro - Valletta, Malta - Giardini Di Naxos (Taormina), Sicily - Palermo, Sicily - Naples, Italy - Civitavecchia (Rome), Italy - View more ports

Silver Muse M

4.6
(17 Reviews)

2026 sail dates:

$10800*
$982/night*
Suite
View Deal
$10800* luxurycruiseconnections.com $10800* luxuryonly.com $10800* gotosea.com $10800* dreamvacations.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 17 Silver Muse reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$10800*

See Offers

N/A

N/A

N/A

$10800*

See Offers

N/A

N/A

N/A

$10800*

 

N/A

N/A

N/A

$10800*

Ports

  • Sydney, Australia
  • Brisbane, Australia
  • Benoa, Bali, Indonesia
  • Singapore
  • Colombo, Sri Lanka
  • Aqaba (Petra), Jordan
  • Suez Canal Transit
  • Alexandria (Cairo), Egypt
  • Patmos, Greece
  • Kusadasi (Ephesus), Turkey
  • Piraeus (Athens), Greece
  • Valletta, Malta
  • Palermo, Sicily
  • Cartagena, Spain
  • Leixoes (Oporto), Portugal
  • Cobh (Cork), Ireland
  • Cruise English Channel
  • Zeebrugge (Bruges), Belgium
  • Gdansk (Danzig), Poland
  • Visby, Sweden
  • Helsinki, Finland
  • Tallinn, Estonia
  • Stockholm, Sweden
  • Copenhagen, Denmark
  • Ijmuiden (Amsterdam), Netherlands
  • Dover (London), England
  • Invergordon (Inverness & Loch Ness), Scotland
  • Lerwick, Shetland Islands, Scotland
  • Akureyri, Iceland
  • Isafjordur, Iceland
  • Reykjavik, Iceland
  • Corner Brook, Newfoundland
  • Cruise Gulf Of St. Lawrence
  • Quebec City, Quebec
  • SAGUENAY, QUEBEC, CANADA
  • Charlottetown, Prince Edward Island
  • CAPE BRETON ISLAND, NOVIA SCOTIA, CANADA
  • Halifax, Nova Scotia
  • New York, New York
View more ports

Ports

Sydney, Australia - Brisbane, Australia - Benoa, Bali, Indonesia - Singapore - Colombo, Sri Lanka - Aqaba (Petra), Jordan - Suez Canal Transit - Alexandria (Cairo), Egypt - Patmos, Greece - Kusadasi (Ephesus), Turkey - Piraeus (Athens), Greece - Valletta, Malta - Palermo, Sicily - Cartagena, Spain - Leixoes (Oporto), Portugal - Cobh (Cork), Ireland - Cruise English Channel - Zeebrugge (Bruges), Belgium - Gdansk (Danzig), Poland - Visby, Sweden - Helsinki, Finland - Tallinn, Estonia - Stockholm, Sweden - Copenhagen, Denmark - Ijmuiden (Amsterdam), Netherlands - Dover (London), England - Invergordon (Inverness & Loch Ness), Scotland - Lerwick, Shetland Islands, Scotland - Akureyri, Iceland - Isafjordur, Iceland - Reykjavik, Iceland - Corner Brook, Newfoundland - Cruise Gulf Of St. Lawrence - Quebec City, Quebec - SAGUENAY, QUEBEC, CANADA - Charlottetown, Prince Edward Island - CAPE BRETON ISLAND, NOVIA SCOTIA, CANADA - Halifax, Nova Scotia - New York, New York - View more ports

Crown Princess L

3.9
(1394 Reviews)

2026 sail dates:

$13358*
$173/night*
Inside
View Deal
$13358* princess.com $13360* cruisesonly.com $13358* gotosea.com $13360* dreamvacations.com $13358* directlinecruises.com $13358* americandiscountcruises.com $13360* cruises.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 1394 Crown Princess reviews

Ports

  • Sydney, Australia
  • Brisbane, Australia
  • Benoa, Bali, Indonesia
  • Singapore
  • Colombo, Sri Lanka
  • Aqaba (Petra), Jordan
  • Suez Canal Transit
  • Alexandria (Cairo), Egypt
  • Patmos, Greece
  • Kusadasi (Ephesus), Turkey
  • Piraeus (Athens), Greece
  • Valletta, Malta
  • Palermo, Sicily
  • Cartagena, Spain
  • Leixoes (Oporto), Portugal
  • Cobh (Cork), Ireland
  • Cruise English Channel
  • Zeebrugge (Bruges), Belgium
  • Gdansk (Danzig), Poland
  • Visby, Sweden
  • Helsinki, Finland
  • Tallinn, Estonia
  • Stockholm, Sweden
  • Copenhagen, Denmark
  • Ijmuiden (Amsterdam), Netherlands
  • Dover (London), England
  • Invergordon (Inverness & Loch Ness), Scotland
  • Lerwick, Shetland Islands, Scotland
  • Akureyri, Iceland
  • Isafjordur, Iceland
  • Reykjavik, Iceland
  • Corner Brook, Newfoundland
  • Cruise Gulf Of St. Lawrence
  • Quebec City, Quebec
  • SAGUENAY, QUEBEC, CANADA
  • Charlottetown, Prince Edward Island
  • CAPE BRETON ISLAND, NOVIA SCOTIA, CANADA
  • Halifax, Nova Scotia
  • New York, New York
  • Miami, Florida
  • Cartagena, Colombia
  • Panama Canal Transit
  • Manta, Ecuador
  • Callao (Lima), Peru
  • General San Martin (Pisco), Peru
  • Easter Island
  • Adamstown, Pitcairn Islands
  • Papeete, Tahiti
  • Moorea, French Polynesia
  • Cross International Dateline
  • Auckland, New Zealand
View more ports

Ports

Sydney, Australia - Brisbane, Australia - Benoa, Bali, Indonesia - Singapore - Colombo, Sri Lanka - Aqaba (Petra), Jordan - Suez Canal Transit - Alexandria (Cairo), Egypt - Patmos, Greece - Kusadasi (Ephesus), Turkey - Piraeus (Athens), Greece - Valletta, Malta - Palermo, Sicily - Cartagena, Spain - Leixoes (Oporto), Portugal - Cobh (Cork), Ireland - Cruise English Channel - Zeebrugge (Bruges), Belgium - Gdansk (Danzig), Poland - Visby, Sweden - Helsinki, Finland - Tallinn, Estonia - Stockholm, Sweden - Copenhagen, Denmark - Ijmuiden (Amsterdam), Netherlands - Dover (London), England - Invergordon (Inverness & Loch Ness), Scotland - Lerwick, Shetland Islands, Scotland - Akureyri, Iceland - Isafjordur, Iceland - Reykjavik, Iceland - Corner Brook, Newfoundland - Cruise Gulf Of St. Lawrence - Quebec City, Quebec - SAGUENAY, QUEBEC, CANADA - Charlottetown, Prince Edward Island - CAPE BRETON ISLAND, NOVIA SCOTIA, CANADA - Halifax, Nova Scotia - New York, New York - Miami, Florida - Cartagena, Colombia - Panama Canal Transit - Manta, Ecuador - Callao (Lima), Peru - General San Martin (Pisco), Peru - Easter Island - Adamstown, Pitcairn Islands - Papeete, Tahiti - Moorea, French Polynesia - Cross International Dateline - Auckland, New Zealand - View more ports

Crown Princess L

3.9
(1394 Reviews)

2026 sail dates:

$18008*
$158/night*
Inside
View Deal
$18008* princess.com $18009* cruisesonly.com $18008* gotosea.com $18009* dreamvacations.com $18008* directlinecruises.com $18008* americandiscountcruises.com $18009* cruises.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 1394 Crown Princess reviews

Ports

  • Sydney, Australia
  • Brisbane, Australia
  • Benoa, Bali, Indonesia
  • Singapore
  • Colombo, Sri Lanka
  • Aqaba (Petra), Jordan
  • Suez Canal Transit
  • Alexandria (Cairo), Egypt
  • Patmos, Greece
  • Kusadasi (Ephesus), Turkey
  • Piraeus (Athens), Greece
  • Valletta, Malta
  • Palermo, Sicily
  • Cartagena, Spain
  • Leixoes (Oporto), Portugal
  • Cobh (Cork), Ireland
  • Cruise English Channel
  • Zeebrugge (Bruges), Belgium
  • Gdansk (Danzig), Poland
  • Visby, Sweden
  • Helsinki, Finland
  • Tallinn, Estonia
  • Stockholm, Sweden
  • Copenhagen, Denmark
  • Ijmuiden (Amsterdam), Netherlands
  • Dover (London), England
View more ports

Ports

Sydney, Australia - Brisbane, Australia - Benoa, Bali, Indonesia - Singapore - Colombo, Sri Lanka - Aqaba (Petra), Jordan - Suez Canal Transit - Alexandria (Cairo), Egypt - Patmos, Greece - Kusadasi (Ephesus), Turkey - Piraeus (Athens), Greece - Valletta, Malta - Palermo, Sicily - Cartagena, Spain - Leixoes (Oporto), Portugal - Cobh (Cork), Ireland - Cruise English Channel - Zeebrugge (Bruges), Belgium - Gdansk (Danzig), Poland - Visby, Sweden - Helsinki, Finland - Tallinn, Estonia - Stockholm, Sweden - Copenhagen, Denmark - Ijmuiden (Amsterdam), Netherlands - Dover (London), England - View more ports

Crown Princess L

3.9
(1394 Reviews)

2026 sail dates:

$9548*
$174/night*
Inside
View Deal
$9548* princess.com $9549* cruisesonly.com $9548* gotosea.com $9549* dreamvacations.com $9548* directlinecruises.com $9548* americandiscountcruises.com $9549* cruises.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 1394 Crown Princess reviews

Ports

  • Brisbane, Australia
  • Benoa, Bali, Indonesia
  • Singapore
  • Colombo, Sri Lanka
  • Aqaba (Petra), Jordan
  • Suez Canal Transit
  • Alexandria (Cairo), Egypt
  • Patmos, Greece
  • Kusadasi (Ephesus), Turkey
  • Piraeus (Athens), Greece
  • Valletta, Malta
  • Palermo, Sicily
  • Cartagena, Spain
  • Oporto, Portugal
  • Cobh (Cork), Ireland
  • Zeebrugge (Bruges), Belgium
  • Gdynia (Gdansk), Poland
  • Visby, Sweden
  • Helsinki, Finland
  • Tallinn, Estonia
  • Stockholm, Sweden
  • Copenhagen, Denmark
  • Ijmuiden (Amsterdam), Netherlands
  • Dover (London), England
View more ports

Ports

Brisbane, Australia - Benoa, Bali, Indonesia - Singapore - Colombo, Sri Lanka - Aqaba (Petra), Jordan - Suez Canal Transit - Alexandria (Cairo), Egypt - Patmos, Greece - Kusadasi (Ephesus), Turkey - Piraeus (Athens), Greece - Valletta, Malta - Palermo, Sicily - Cartagena, Spain - Oporto, Portugal - Cobh (Cork), Ireland - Zeebrugge (Bruges), Belgium - Gdynia (Gdansk), Poland - Visby, Sweden - Helsinki, Finland - Tallinn, Estonia - Stockholm, Sweden - Copenhagen, Denmark - Ijmuiden (Amsterdam), Netherlands - Dover (London), England - View more ports

Crown Princess L

3.9
(1394 Reviews)

2026 sail dates:

$9205*
$174/night*
Inside
View Deal
$9205* princess.com $9205* cruisesonly.com $9205* gotosea.com $9205* dreamvacations.com $9205* directlinecruises.com $9204* americandiscountcruises.com $9205* cruises.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 1394 Crown Princess reviews

Ports

  • Brisbane, Australia
  • Benoa, Bali, Indonesia
  • Singapore
  • Colombo, Sri Lanka
  • Aqaba (Petra), Jordan
  • Suez Canal Transit
  • Alexandria (Cairo), Egypt
  • Patmos, Greece
  • Kusadasi (Ephesus), Turkey
  • Piraeus (Athens), Greece
  • Valletta, Malta
  • Palermo, Sicily
  • Cartagena, Spain
  • Oporto, Portugal
  • Cobh (Cork), Ireland
  • Zeebrugge (Bruges), Belgium
  • Gdynia (Gdansk), Poland
  • Visby, Sweden
  • Helsinki, Finland
  • Tallinn, Estonia
  • Stockholm, Sweden
  • Copenhagen, Denmark
  • Ijmuiden (Amsterdam), Netherlands
  • Dover (London), England
  • Invergordon (Inverness & Loch Ness), Scotland
  • Lerwick, Shetland Islands, Scotland
  • Akureyri, Iceland
  • Isafjordur, Iceland
  • Reykjavik, Iceland
  • Corner Brook, Newfoundland
  • Quebec City, Quebec
  • SAGUENAY, QUEBEC, CANADA
  • Charlottetown, Prince Edward Island
  • Sydney, Nova Scotia
  • Halifax, Nova Scotia
  • New York, New York
  • Miami, Florida
  • Cartagena, Colombia
  • Panama Canal Transit
  • Manta, Ecuador
  • Callao (Lima), Peru
  • General San Martin (Pisco), Peru
  • Easter Island
  • Adamstown, Pitcairn Islands
  • Papeete, Tahiti
  • Moorea, French Polynesia
  • Cross International Dateline
  • Auckland, New Zealand
  • Sydney, Australia
View more ports

Ports

Brisbane, Australia - Benoa, Bali, Indonesia - Singapore - Colombo, Sri Lanka - Aqaba (Petra), Jordan - Suez Canal Transit - Alexandria (Cairo), Egypt - Patmos, Greece - Kusadasi (Ephesus), Turkey - Piraeus (Athens), Greece - Valletta, Malta - Palermo, Sicily - Cartagena, Spain - Oporto, Portugal - Cobh (Cork), Ireland - Zeebrugge (Bruges), Belgium - Gdynia (Gdansk), Poland - Visby, Sweden - Helsinki, Finland - Tallinn, Estonia - Stockholm, Sweden - Copenhagen, Denmark - Ijmuiden (Amsterdam), Netherlands - Dover (London), England - Invergordon (Inverness & Loch Ness), Scotland - Lerwick, Shetland Islands, Scotland - Akureyri, Iceland - Isafjordur, Iceland - Reykjavik, Iceland - Corner Brook, Newfoundland - Quebec City, Quebec - SAGUENAY, QUEBEC, CANADA - Charlottetown, Prince Edward Island - Sydney, Nova Scotia - Halifax, Nova Scotia - New York, New York - Miami, Florida - Cartagena, Colombia - Panama Canal Transit - Manta, Ecuador - Callao (Lima), Peru - General San Martin (Pisco), Peru - Easter Island - Adamstown, Pitcairn Islands - Papeete, Tahiti - Moorea, French Polynesia - Cross International Dateline - Auckland, New Zealand - Sydney, Australia - View more ports

Crown Princess L

3.9
(1394 Reviews)

2026 sail dates:

$18005*
$158/night*
Inside
View Deal
$18005* princess.com $18005* cruisesonly.com $18005* gotosea.com $18005* dreamvacations.com $18005* directlinecruises.com $18004* americandiscountcruises.com $18005* cruises.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 1394 Crown Princess reviews

Ports

  • Valletta, Malta
  • Syracuse, Sicily
  • Taormina, Sicily
  • Palermo, Sicily
  • Cagliari, Sardinia
  • Bonifacio, Corsica
  • Portoferraio, Elba
  • Nice, France
View more ports

Ports

Valletta, Malta - Syracuse, Sicily - Taormina, Sicily - Palermo, Sicily - Cagliari, Sardinia - Bonifacio, Corsica - Portoferraio, Elba - Nice, France - View more ports

Le Bougainville S

2026 sail dates:

$7320*
$1046/night*
Balcony
View Deal
$7320* luxurycruiseconnections.com $7380* luxuryonly.com $7380* dreamvacations.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$7320*

$12250*

See Offers

N/A

N/A

$7380*

$12250*

 

N/A

N/A

$7380*

$12250*

Ports

  • Civitavecchia (Rome), Italy
  • Amalfi, Italy
  • Palermo, Sicily
  • Porto Cervo (Olbia), Sardinia
  • Bastia, Corsica
  • Piombino, Italy
  • Livorno (Florence & Pisa), Italy
  • Villefranche-Sur-Mer, France
  • St. Tropez, France
  • Toulon, France
  • Barcelona, Spain
View more ports

Ports

Civitavecchia (Rome), Italy - Amalfi, Italy - Palermo, Sicily - Porto Cervo (Olbia), Sardinia - Bastia, Corsica - Piombino, Italy - Livorno (Florence & Pisa), Italy - Villefranche-Sur-Mer, France - St. Tropez, France - Toulon, France - Barcelona, Spain - View more ports

Nautica S

4.1
(97 Reviews)

2026 sail dates:

$3199*
$320/night*
Inside
View Deal
$3199* luxurycruiseconnections.com $3199* avoyatravel.com $3199* luxuryonly.com $3199* gotosea.com $3199* dreamvacations.com $3199* americandiscountcruises.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 97 Nautica reviews

Ports

  • Civitavecchia (Rome), Italy
  • Salerno (Naples), Italy
  • Palermo, Sicily
  • Cagliari, Sardinia
  • Palma De Mallorca, Balearic Islands
  • Alicante, Spain
  • Gibraltar (U.K.)
  • Cadiz (Seville), Spain
  • Lisbon, Portugal
View more ports

Ports

Civitavecchia (Rome), Italy - Salerno (Naples), Italy - Palermo, Sicily - Cagliari, Sardinia - Palma De Mallorca, Balearic Islands - Alicante, Spain - Gibraltar (U.K.) - Cadiz (Seville), Spain - Lisbon, Portugal - View more ports

Oosterdam M

4.1
(889 Reviews)

2026 sail dates:

$1764*
$176/night*
Inside
View Deal
$1764* hollandamerica.com $1752* cruisesonly.com $1809* americandiscountvacations.com $1809* gotosea.com $1752* dreamvacations.com $1809* cruisehub.com $1809* americandiscountcruises.com $1752* cruises.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 889 Oosterdam reviews

Ports

  • Civitavecchia (Rome), Italy
  • Salerno (Naples), Italy
  • Palermo, Sicily
  • Cagliari, Sardinia
  • Palma De Mallorca, Balearic Islands
  • Alicante, Spain
  • Gibraltar (U.K.)
  • Cadiz (Seville), Spain
  • Lisbon, Portugal
  • Tangier, Morocco
  • Valencia, Spain
  • Valletta, Malta
  • Cruise Strait Of Messina
  • Cruise Stromboli Volcano
View more ports

Ports

Civitavecchia (Rome), Italy - Salerno (Naples), Italy - Palermo, Sicily - Cagliari, Sardinia - Palma De Mallorca, Balearic Islands - Alicante, Spain - Gibraltar (U.K.) - Cadiz (Seville), Spain - Lisbon, Portugal - Tangier, Morocco - Valencia, Spain - Valletta, Malta - Cruise Strait Of Messina - Cruise Stromboli Volcano - View more ports

Oosterdam M

4.1
(889 Reviews)

2026 sail dates:

$3549*
$169/night*
Inside
View Deal
$3549* hollandamerica.com $3599* cruisesonly.com $3599* americandiscountvacations.com $3599* gotosea.com $3599* dreamvacations.com $3599* cruisehub.com $3599* americandiscountcruises.com $3599* cruises.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 889 Oosterdam reviews
131 - 140 of 156

All prices are per person based on double occupancy and do not include port/government fees and gratuities.