Colon, Panama cruises 225 Colon, Panama cruises

Your search Clear selections

Any Destination
All Sail Months
Any Length
Colon, Panama
Any Cruise Line
Any Ship

Close

225 cruises found

Sort by

Filter by

More

Ports

  • Colon, Panama
  • FORT SAN LORENZO, PANAMA
  • San Blas Islands, Panama
  • Panama Canal Transit
  • ISLA PACHECA, PEARL ISLANDS, PANAMA
  • Cruise & Explore Pearl Islands
  • PLAYA MUERTO, DARIEN, PANAMA
  • CEBACO ISLAND, PANAMA
  • RIO ESQUINAS, COSTA RICA
  • CORCOVADO NATIONAL PARK, COSTA RICA
  • Curu (Reserve), Costa Rica
  • Puntarenas, Costa Rica
View more ports

Ports

Colon, Panama - FORT SAN LORENZO, PANAMA - San Blas Islands, Panama - Panama Canal Transit - ISLA PACHECA, PEARL ISLANDS, PANAMA - Cruise & Explore Pearl Islands - PLAYA MUERTO, DARIEN, PANAMA - CEBACO ISLAND, PANAMA - RIO ESQUINAS, COSTA RICA - CORCOVADO NATIONAL PARK, COSTA RICA - Curu (Reserve), Costa Rica - Puntarenas, Costa Rica - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$9790*

$24930*

See Offers

N/A

N/A

$9620*

$16730*

 

N/A

N/A

$9620*

$16730*

 

N/A

N/A

$10350*

$23720*

See Offers

N/A

N/A

$9340*

$15930*

 

N/A

N/A

$9340*

$15930*

Ports

  • Puntarenas, Costa Rica
  • Curu (Reserve), Costa Rica
  • CORCOVADO NATIONAL PARK, COSTA RICA
  • RIO ESQUINAS, COSTA RICA
  • CEBACO ISLAND, PANAMA
  • PLAYA MUERTO, DARIEN, PANAMA
  • Cruise & Explore Pearl Islands
  • ISLA PACHECA, PEARL ISLANDS, PANAMA
  • Panama Canal Transit
  • San Blas Islands, Panama
  • FORT SAN LORENZO, PANAMA
  • Colon, Panama
View more ports

Ports

Puntarenas, Costa Rica - Curu (Reserve), Costa Rica - CORCOVADO NATIONAL PARK, COSTA RICA - RIO ESQUINAS, COSTA RICA - CEBACO ISLAND, PANAMA - PLAYA MUERTO, DARIEN, PANAMA - Cruise & Explore Pearl Islands - ISLA PACHECA, PEARL ISLANDS, PANAMA - Panama Canal Transit - San Blas Islands, Panama - FORT SAN LORENZO, PANAMA - Colon, Panama - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$10860*

$15930*

See Offers

N/A

N/A

$9340*

$15930*

 

N/A

N/A

$9340*

$15930*

 

N/A

N/A

$12030*

$23770*

See Offers

N/A

N/A

$9790*

$16730*

 

N/A

N/A

$9790*

$16730*

Ports

  • Ft. Lauderdale (Port Everglades), Florida
  • Willemstad, Curacao
  • Kralendijk, Bonaire
  • Oranjestad, Aruba
  • Half Moon Cay, Bahamas (Private Island)
  • Cartagena, Colombia
  • Colon, Panama
  • Panama Canal (Cruise Into Canal)
  • Puerto Limon, Costa Rica
  • Key West, Florida
View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Willemstad, Curacao - Kralendijk, Bonaire - Oranjestad, Aruba - Half Moon Cay, Bahamas (Private Island) - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - Key West, Florida - View more ports

Ports

  • Buenos Aires, Argentina
  • Ushuaia, Tierra Del Fuego, Argentina
  • Cruise Drake Passage
  • Antarctic Experience
  • Cruise Cape Horn
  • Cruise Garibaldi Glacier
  • CRUISE & EXPLORE CHILEAN GLACIERS
  • Punta Arenas, Chile
  • Cruise Chilean Fjords
  • Puerto Chacabuco, Chile
  • Castro, Isla Chiloe, Chile
  • Valparaiso (Santiago), Chile
  • Iquique, Chile
  • Callao (Lima), Peru
  • Manta, Ecuador
  • Panama Canal Transit
  • Colon, Panama
  • Cozumel, Mexico
  • Ft. Lauderdale (Port Everglades), Florida
View more ports

Ports

Buenos Aires, Argentina - Ushuaia, Tierra Del Fuego, Argentina - Cruise Drake Passage - Antarctic Experience - Cruise Cape Horn - Cruise Garibaldi Glacier - CRUISE & EXPLORE CHILEAN GLACIERS - Punta Arenas, Chile - Cruise Chilean Fjords - Puerto Chacabuco, Chile - Castro, Isla Chiloe, Chile - Valparaiso (Santiago), Chile - Iquique, Chile - Callao (Lima), Peru - Manta, Ecuador - Panama Canal Transit - Colon, Panama - Cozumel, Mexico - Ft. Lauderdale (Port Everglades), Florida - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$33985*

N/A

See Offers

N/A

N/A

$33985*

N/A

 

N/A

N/A

$33985*

N/A

 

N/A

N/A

$32885*

$48885*

See Offers

N/A

N/A

$32885*

$48885*

 

N/A

N/A

$32885*

$48885*

Ports

  • Buenos Aires, Argentina
  • Ushuaia, Tierra Del Fuego, Argentina
  • Cruise Drake Passage
  • Antarctic Experience
  • South Georgia Island
  • Port Stanley, Falkland Islands
  • West Point Island, Falkland Islands
  • Cruise Cape Horn
  • Cruise Garibaldi Glacier
  • Cruise Chilean Fjords
  • Punta Arenas, Chile
  • Puerto Chacabuco, Chile
  • Valparaiso (Santiago), Chile
  • Iquique, Chile
  • Callao (Lima), Peru
  • Manta, Ecuador
  • Panama Canal Transit
  • Colon, Panama
  • Cozumel, Mexico
  • Ft. Lauderdale (Port Everglades), Florida
  • Charleston, South Carolina
  • Norfolk, Virginia
  • Lunenburg, Nova Scotia
  • CAPE BRETON ISLAND, NOVIA SCOTIA, CANADA
  • Cap-Aux-Meules, Quebec
  • Cruise St. Lawrence River
  • Quebec City, Quebec
  • Trois-Rivieres, Quebec
  • Toronto, Ontario
  • NIAGARA FALLS, ONTARIO, CANADA
  • POINT PELEE, ONTARIO, CANADA
  • DETROIT, MICHIGAN
  • ALPENA, MICHIGAN
  • MACKINAC ISLAND, MI
  • MILWAUKEE, WI
View more ports

Ports

Buenos Aires, Argentina - Ushuaia, Tierra Del Fuego, Argentina - Cruise Drake Passage - Antarctic Experience - South Georgia Island - Port Stanley, Falkland Islands - West Point Island, Falkland Islands - Cruise Cape Horn - Cruise Garibaldi Glacier - Cruise Chilean Fjords - Punta Arenas, Chile - Puerto Chacabuco, Chile - Valparaiso (Santiago), Chile - Iquique, Chile - Callao (Lima), Peru - Manta, Ecuador - Panama Canal Transit - Colon, Panama - Cozumel, Mexico - Ft. Lauderdale (Port Everglades), Florida - Charleston, South Carolina - Norfolk, Virginia - Lunenburg, Nova Scotia - CAPE BRETON ISLAND, NOVIA SCOTIA, CANADA - Cap-Aux-Meules, Quebec - Cruise St. Lawrence River - Quebec City, Quebec - Trois-Rivieres, Quebec - Toronto, Ontario - NIAGARA FALLS, ONTARIO, CANADA - POINT PELEE, ONTARIO, CANADA - DETROIT, MICHIGAN - ALPENA, MICHIGAN - MACKINAC ISLAND, MI - MILWAUKEE, WI - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$79995*

See Offers

N/A

N/A

N/A

$79995*

 

N/A

N/A

N/A

$79995*

Ports

  • Ft. Lauderdale (Port Everglades), Florida
  • Half Moon Cay, Bahamas (Private Island)
  • Oranjestad, Aruba
  • Cartagena, Colombia
  • Colon, Panama
  • Panama Canal (Cruise Into Canal)
  • Puerto Limon, Costa Rica
  • George Town, Grand Cayman
  • Willemstad, Curacao
  • Kralendijk, Bonaire
View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Half Moon Cay, Bahamas (Private Island) - Oranjestad, Aruba - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - George Town, Grand Cayman - Willemstad, Curacao - Kralendijk, Bonaire - View more ports

Ports

  • Ft. Lauderdale (Port Everglades), Florida
  • Half Moon Cay, Bahamas (Private Island)
  • Oranjestad, Aruba
  • Cartagena, Colombia
  • Panama Canal (Cruise Into Canal)
  • Colon, Panama
  • Puerto Limon, Costa Rica
  • George Town, Grand Cayman
View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Half Moon Cay, Bahamas (Private Island) - Oranjestad, Aruba - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports

Ports

  • Puerto Caldera, Costa Rica
  • Puerto Quepos, Costa Rica
  • PUERTO JIMENEZ (GOLFO DULCE), COSTA RICA
  • ISLA PARIDA, PANAMA
  • Fuerte Amador, Panama
  • Panama Canal Transit
  • Colon, Panama
  • Cartagena, Colombia
  • Santa Marta, Colombia
  • Oranjestad, Aruba
  • Willemstad, Curacao
  • Kralendijk, Bonaire
  • St. George's, Grenada
  • Mayreau, Grenadines
  • Bridgetown, Barbados
View more ports

Ports

Puerto Caldera, Costa Rica - Puerto Quepos, Costa Rica - PUERTO JIMENEZ (GOLFO DULCE), COSTA RICA - ISLA PARIDA, PANAMA - Fuerte Amador, Panama - Panama Canal Transit - Colon, Panama - Cartagena, Colombia - Santa Marta, Colombia - Oranjestad, Aruba - Willemstad, Curacao - Kralendijk, Bonaire - St. George's, Grenada - Mayreau, Grenadines - Bridgetown, Barbados - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

$9600*

N/A

N/A

 

N/A

$9569*

N/A

N/A

See Offers

N/A

$9569*

N/A

N/A

Ports

  • Colon, Panama
  • Panama Canal Transit
  • Balboa, Panama
  • ISLA PARIDA, PANAMA
  • PUERTO JIMENEZ (GOLFO DULCE), COSTA RICA
  • Puerto Quepos, Costa Rica
  • Puerto Caldera, Costa Rica
View more ports

Ports

Colon, Panama - Panama Canal Transit - Balboa, Panama - ISLA PARIDA, PANAMA - PUERTO JIMENEZ (GOLFO DULCE), COSTA RICA - Puerto Quepos, Costa Rica - Puerto Caldera, Costa Rica - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

$3969*

N/A

N/A

 

N/A

$4799*

N/A

$7569*

 

N/A

$4569*

N/A

N/A

See Offers

N/A

$4569*

N/A

N/A

Ports

  • Ft. Lauderdale (Port Everglades), Florida
  • Cartagena, Colombia
  • Colon, Panama
  • Panama Canal (Cruise Into Canal)
  • Oranjestad, Aruba
  • Kralendijk, Bonaire
  • George Town, Grand Cayman
View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Oranjestad, Aruba - Kralendijk, Bonaire - George Town, Grand Cayman - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

$1410*

N/A

N/A

N/A

See Offers

$1410*

N/A

N/A

N/A

See Offers

$1410*

N/A

N/A

N/A

See Offers

$1410*

N/A

N/A

N/A

See Offers

$1410*

N/A

N/A

N/A

 

$1410*

N/A

N/A

N/A

See Offers

$1410*

N/A

N/A

N/A

See Offers

$1410*

N/A

N/A

N/A

All prices are per person based on double occupancy and do not include port/government fees and gratuities.