Colon, Panama cruises 228 Colon, Panama cruises

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Colon, Panama

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228 cruises found

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Ports

Ft. Lauderdale (Port Everglades), Florida
Cartagena, Colombia
Colon, Panama
Panama Canal (Cruise Into Canal)
Oranjestad, Aruba
Willemstad, Curacao
Kralendijk, Bonaire

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Ports

Ft. Lauderdale (Port Everglades), Florida - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Oranjestad, Aruba - Willemstad, Curacao - Kralendijk, Bonaire - View more ports

11 Night Panama Canal & Southern Caribbean (Ft. Lauderdale Roundtrip)

Celebrity Ascent L

4.6

(73 Reviews)

2026 sail dates: Nov 23

2027 sail dates: Mar 08

$2211*

$201/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$2211*	$2411*	$2751*	$7277*
See Offers	$2211*	$2411*	$2751*	$7276*
	$2211*	$2411*	$2751*	$7276*
See Offers	$2211*	$2411*	$2751*	$7277*
See Offers	$2211*	$2411*	$2751*	$7277*
See Offers	$2211*	$2411*	$2751*	$7276*
See Offers	$2211*	$2411*	$2751*	$7277*
See Offers	$2211*	$2411*	$2751*	$7277*
	$2212*	$2412*	$2752*	$7278*
See Offers	$2212*	$2412*	$2752*	$7277*
	$2212*	$2412*	$2752*	$7277*
See Offers	$2212*	$2412*	$2752*	$7278*
See Offers	$2212*	$2412*	$2752*	$7278*
See Offers	$2212*	$2412*	$2752*	$7277*
See Offers	$2212*	$2412*	$2752*	$7278*
See Offers	$2212*	$2412*	$2752*	$7278*

Ports

Tampa, Florida
George Town, Grand Cayman
Cartagena, Colombia
Colon, Panama
Panama Canal (Cruise Into Canal)
Puerto Limon, Costa Rica
Harvest Caye, Belize
Cozumel, Mexico

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Ports

Tampa, Florida - George Town, Grand Cayman - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - Harvest Caye, Belize - Cozumel, Mexico - View more ports

11 Night Panama Canal Partial Transit: Mexico Costa Rica & Belize (Tampa Roundtrip)

Norwegian Sky M

3.7

(3375 Reviews)

2026 sail dates: Nov 30

2027 sail dates: Mar 08

$1432*

$130/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1432*	$1632*	$2932*	$5932*
See Offers	$1432*	$1632*	$2932*	$5932*
	$1432*	$1632*	$2932*	$5932*
See Offers	$1432*	$1632*	$2932*	$5932*
See Offers	$1432*	$1632*	$2932*	$5932*
See Offers	$1432*	$1632*	$2932*	$5932*
See Offers	$1432*	$1632*	$2932*	$5932*
See Offers	$1432*	$1632*	$2932*	$5932*
See Offers	$1432*	$1632*	$2932*	$5932*
See Offers	$1434*	$1634*	$3134*	$5134*
See Offers	$1434*	$1634*	$3134*	$5134*
	$1434*	$1634*	$3134*	$5134*
See Offers	$1434*	$1634*	$3134*	$5134*
See Offers	$1434*	$1634*	$3134*	$5134*
See Offers	$1434*	$1634*	$3134*	$5134*
See Offers	$1434*	$1634*	$3134*	$5134*
See Offers	$1434*	$1634*	$3134*	$5134*
See Offers	$1434*	$1634*	$3134*	$5134*

Ports

Tampa, Florida
Cozumel, Mexico
Harvest Caye, Belize
Puerto Limon, Costa Rica
Panama Canal (Cruise Into Canal)
Colon, Panama
Willemstad, Curacao
Oranjestad, Aruba
CABO ROJO, DOMINICAN REPUBLIC
Great Stirrup Cay (Cruise Line Private Island), Bahamas

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Ports

Tampa, Florida - Cozumel, Mexico - Harvest Caye, Belize - Puerto Limon, Costa Rica - Panama Canal (Cruise Into Canal) - Colon, Panama - Willemstad, Curacao - Oranjestad, Aruba - CABO ROJO, DOMINICAN REPUBLIC - Great Stirrup Cay (Cruise Line Private Island), Bahamas - View more ports

14 Night Panama Canal: Mexico Bahamas & Costa Rica (Tampa Roundtrip)

Norwegian Sky M

3.7

(3375 Reviews)

2026 sail dates: Dec 21

$2456*

$175/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$2456*	$3106*	$4506*	$9006*
See Offers	$2428*	$3106*	$4498*	$9006*
	$2428*	$3106*	$4498*	$9006*
See Offers	$2456*	$3106*	$4506*	$9006*
See Offers	$2428*	$3106*	$4498*	$9006*
See Offers	$2456*	$3106*	$4506*	$9006*
See Offers	$2456*	$3106*	$4506*	$9006*
See Offers	$2428*	$3106*	$4498*	$9006*
See Offers	$2456*	$3106*	$4506*	$9006*

Ports

Miami, Florida
Costa Maya (Mahahual), Mexico
Harvest Caye, Belize
Coxen Hole, Roatan, Bay Islands, Honduras
George Town, Grand Cayman
Ocho Rios, Jamaica
Puerto Limon, Costa Rica
Cartagena, Colombia
Colon, Panama
Panama City, Panama
Panama Canal Transit

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Ports

Miami, Florida - Costa Maya (Mahahual), Mexico - Harvest Caye, Belize - Coxen Hole, Roatan, Bay Islands, Honduras - George Town, Grand Cayman - Ocho Rios, Jamaica - Puerto Limon, Costa Rica - Cartagena, Colombia - Colon, Panama - Panama City, Panama - Panama Canal Transit - View more ports

14 Night Exotic Coasts & Casco Viejo (Miami To Panama City)

Seven Seas Grandeur M

4.1

(7 Reviews)

2027 sail dates: Feb 23

$8799*

$629/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	N/A	N/A	N/A	$8799*
See Offers	N/A	N/A	N/A	$8799*
	N/A	N/A	N/A	$8799*
See Offers	N/A	N/A	N/A	$8799*

Ports

Miami, Florida
Ocho Rios, Jamaica
Oranjestad, Aruba
Cartagena, Colombia
Colon, Panama
Puerto Limon, Costa Rica
Coxen Hole, Roatan, Bay Islands, Honduras
Kralendijk, Bonaire
Willemstad, Curacao
CABO ROJO, DOMINICAN REPUBLIC

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Ports

Miami, Florida - Ocho Rios, Jamaica - Oranjestad, Aruba - Cartagena, Colombia - Colon, Panama - Puerto Limon, Costa Rica - Coxen Hole, Roatan, Bay Islands, Honduras - Kralendijk, Bonaire - Willemstad, Curacao - CABO ROJO, DOMINICAN REPUBLIC - View more ports

21 Night Caribbean & Bahamas (Miami Roundtrip)

MSC Divina XL

3.8

(1527 Reviews)

2025 sail dates: Nov 09

$2514*

$120/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$2514*	$2864*	$3274*	$4654*
	$2502*	$2852*	$3262*	$4642*
See Offers	$2514*	$2864*	$3274*	$4654*
	$2514*	$2864*	$3274*	$4654*
See Offers	$2515*	$2865*	$3275*	$4655*
See Offers	$2515*	$2865*	$3275*	$4655*
See Offers	$2514*	$2864*	$3274*	$4654*

Ports

Miami, Florida
CRUISE SOUTH ATLANTIC OCEAN
Cozumel, Mexico
George Town, Grand Cayman
Ocho Rios, Jamaica
Oranjestad, Aruba
Cartagena, Colombia
Colon, Panama
Coxen Hole, Roatan, Bay Islands, Honduras

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Ports

Miami, Florida - CRUISE SOUTH ATLANTIC OCEAN - Cozumel, Mexico - George Town, Grand Cayman - Ocho Rios, Jamaica - Oranjestad, Aruba - Cartagena, Colombia - Colon, Panama - Coxen Hole, Roatan, Bay Islands, Honduras - View more ports

18 Night Caribbean & Bahamas (Miami Roundtrip)

MSC Divina XL

3.8

(1527 Reviews)

2026 sail dates: Mar 22

$1748*

$97/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1748*	$2048*	$2398*	$3588*
	$1736*	$2036*	$2386*	$3576*
See Offers	$1748*	$2048*	$2398*	$3588*
	$1748*	$2048*	$2398*	$3588*
See Offers	$1748*	$2048*	$2398*	$3588*
See Offers	$1748*	$2048*	$2398*	$3588*
See Offers	$1748*	$2048*	$2398*	$3588*

Ports

Miami, Florida
Ocho Rios, Jamaica
Cartagena, Colombia
Colon, Panama
Puerto Limon, Costa Rica
Coxen Hole, Roatan, Bay Islands, Honduras
CRUISE SOUTH ATLANTIC OCEAN

View more ports

Ports

Miami, Florida - Ocho Rios, Jamaica - Cartagena, Colombia - Colon, Panama - Puerto Limon, Costa Rica - Coxen Hole, Roatan, Bay Islands, Honduras - CRUISE SOUTH ATLANTIC OCEAN - View more ports

11 Night Caribbean & Bahamas (Miami Roundtrip)

MSC Divina XL

3.8

(1527 Reviews)

2026 sail dates: Mar 01

$1156*

$105/night*

Inside

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1156*	$1346*	$1526*	$2296*
	$1144*	$1334*	$1514*	$2284*
See Offers	$1156*	$1346*	$1526*	$2288*
	$1156*	$1346*	$1526*	$2288*
See Offers	$1157*	$1347*	$1527*	$2297*
See Offers	$1157*	$1347*	$1527*	$2297*
See Offers	$1156*	$1346*	$1526*	$2288*
See Offers	$1157*	$1347*	$1527*	$2297*

Ports

Miami, Florida
Montego Bay, Jamaica
Cartagena, Colombia
Colon, Panama
Panama Canal (Cruise Into Canal)
Puerto Limon, Costa Rica
Coxen Hole, Roatan, Bay Islands, Honduras
Costa Maya (Mahahual), Mexico

View more ports

Ports

Miami, Florida - Montego Bay, Jamaica - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - Coxen Hole, Roatan, Bay Islands, Honduras - Costa Maya (Mahahual), Mexico - View more ports

11 Night Panama Canal: Mexico Costa Rica & Belize (Miami Roundtrip)

Norwegian Pearl L

3.8

(2051 Reviews)

2025 sail dates: Jan 20

$1166*

$106/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
See Offers	$1166*	$1516*	$3016*	$6606*
See Offers	$1166*	$1516*	$3016*	$3316*
	$1166*	$1516*	$3016*	$3316*
See Offers	$1084*	$1382*	$2657*	$2912*
See Offers	$1166*	$1516*	$3016*	$3316*
See Offers	$1084*	$1382*	$2657*	$2912*
See Offers	$1084*	$1382*	$2657*	$2912*
See Offers	$1166*	$1516*	$3016*	$3316*
See Offers	$1084*	$1382*	$2657*	$2912*

Ports

Miami, Florida
CRUISE SOUTH ATLANTIC OCEAN
Cozumel, Mexico
George Town, Grand Cayman
Ocho Rios, Jamaica
Oranjestad, Aruba
Cartagena, Colombia
Colon, Panama
Puerto Limon, Costa Rica
Coxen Hole, Roatan, Bay Islands, Honduras

View more ports

Ports

Miami, Florida - CRUISE SOUTH ATLANTIC OCEAN - Cozumel, Mexico - George Town, Grand Cayman - Ocho Rios, Jamaica - Oranjestad, Aruba - Cartagena, Colombia - Colon, Panama - Puerto Limon, Costa Rica - Coxen Hole, Roatan, Bay Islands, Honduras - View more ports

18 Night Caribbean & Bahamas (Miami Roundtrip)

MSC Divina XL

3.8

(1527 Reviews)

2025 sail dates: Nov 30

$1698*

$94/night*

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1698*	$1998*	$2348*	$3538*
	$1686*	$1986*	$2336*	$3526*
See Offers	$1698*	$1998*	$2348*	$3538*
	$1698*	$1998*	$2348*	$3538*
See Offers	$1699*	$1999*	$2349*	$3539*
See Offers	$1699*	$1999*	$2349*	$3539*
See Offers	$1698*	$1998*	$2348*	$3538*
See Offers	$1699*	$1999*	$2349*	$3539*

Ports

Miami, Florida
Ocho Rios, Jamaica
Oranjestad, Aruba
Cartagena, Colombia
Colon, Panama
Puerto Limon, Costa Rica
Coxen Hole, Roatan, Bay Islands, Honduras
Philipsburg, St. Maarten
Charlotte Amalie, St. Thomas
Basseterre, St. Kitts
St. John's, Antigua
San Juan, Puerto Rico
Puerto Plata, Dominican Republic

View more ports

Ports

Miami, Florida - Ocho Rios, Jamaica - Oranjestad, Aruba - Cartagena, Colombia - Colon, Panama - Puerto Limon, Costa Rica - Coxen Hole, Roatan, Bay Islands, Honduras - Philipsburg, St. Maarten - Charlotte Amalie, St. Thomas - Basseterre, St. Kitts - St. John's, Antigua - San Juan, Puerto Rico - Puerto Plata, Dominican Republic - View more ports

Caribbean from Miami

MSC Divina XL

3.8

(1527 Reviews)

2025 sail dates: Dec 07

2026 sail dates: Jan 04

$2319*

$110/night*

Inside

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Bonus Offers	Inside	Oceanview	Balcony	Suite
	$2518*	$2868*	$3278*	$4658*
	$2506*	$2856*	$3266*	$4646*
See Offers	$2518*	$2868*	$3278*	$4658*
	$2518*	$2868*	$3278*	$4658*
See Offers	$2519*	$2869*	$3279*	$4659*
See Offers	$2519*	$2869*	$3279*	$4659*
See Offers	$2518*	$2868*	$3278*	$4658*
	$2319*	$2669*	$3079*	$4459*
	$2307*	$2657*	$3067*	$4447*
See Offers	$2319*	$2669*	$3079*	$4459*
	$2319*	$2669*	$3079*	$4459*
See Offers	$2319*	$2669*	$3079*	$4459*
See Offers	$2319*	$2669*	$3079*	$4459*
See Offers	$2319*	$2669*	$3079*	$4459*

91 - 100 of 228

All prices are per person based on double occupancy and do not include port/government fees and gratuities.

Colon, Panama cruises 228 Colon, Panama cruises

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