Cruises to Panama Canal, Central America leaving Miami, Florida cruise port 66 Panama Canal, Central America Cruises Found

Your search Clear selections

Panama Canal, Central America
All Sail Months
Any Length
Miami, Florida
Any Cruise Line
Any Ship

Close

66 cruises found

Sort by

Filter by

More

Ports

  • Miami, Florida
  • Kralendijk, Bonaire
  • Willemstad, Curacao
  • Cartagena, Colombia
  • Fuerte Amador, Panama
  • Panama Canal Transit
  • Puntarenas, Costa Rica
  • Puerto Chiapas (Tapachula), Mexico
  • Puerto Vallarta, Mexico
  • Honolulu, Oahu
  • Nawiliwili, Kauai
  • Cross International Dateline
  • Tokyo, Japan
View more ports

Ports

Miami, Florida - Kralendijk, Bonaire - Willemstad, Curacao - Cartagena, Colombia - Fuerte Amador, Panama - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Chiapas (Tapachula), Mexico - Puerto Vallarta, Mexico - Honolulu, Oahu - Nawiliwili, Kauai - Cross International Dateline - Tokyo, Japan - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$12239*

 

N/A

N/A

N/A

$12239*

See Offers

N/A

N/A

N/A

$12239*

See Offers

N/A

N/A

N/A

$12239*

Ports

  • Miami, Florida
  • Kralendijk, Bonaire
  • Willemstad, Curacao
  • Cartagena, Colombia
  • Panama Canal Transit
  • Fuerte Amador, Panama
View more ports

Ports

Miami, Florida - Kralendijk, Bonaire - Willemstad, Curacao - Cartagena, Colombia - Panama Canal Transit - Fuerte Amador, Panama - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$3779*

 

N/A

N/A

N/A

$3779*

See Offers

N/A

N/A

N/A

$3779*

See Offers

N/A

N/A

N/A

$3779*

Ports

  • Miami, Florida
  • Kralendijk, Bonaire
  • Willemstad, Curacao
  • Cartagena, Colombia
  • Fuerte Amador, Panama
  • Panama Canal Transit
  • Puntarenas, Costa Rica
  • Puerto Chiapas (Tapachula), Mexico
  • Puerto Vallarta, Mexico
  • Honolulu, Oahu
  • Nawiliwili, Kauai
  • Cross International Dateline
  • Tokyo, Japan
  • Osaka, Japan
  • Kochi, Japan
  • Keelung (Taipei), Taiwan
  • Hong Kong
View more ports

Ports

Miami, Florida - Kralendijk, Bonaire - Willemstad, Curacao - Cartagena, Colombia - Fuerte Amador, Panama - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Chiapas (Tapachula), Mexico - Puerto Vallarta, Mexico - Honolulu, Oahu - Nawiliwili, Kauai - Cross International Dateline - Tokyo, Japan - Osaka, Japan - Kochi, Japan - Keelung (Taipei), Taiwan - Hong Kong - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$16199*

 

N/A

N/A

N/A

$16199*

See Offers

N/A

N/A

N/A

$16199*

See Offers

N/A

N/A

N/A

$16199*

Ports

  • Miami, Florida
  • Kralendijk, Bonaire
  • Willemstad, Curacao
  • Cartagena, Colombia
  • Fuerte Amador, Panama
  • Panama Canal Transit
  • Puntarenas, Costa Rica
  • Puerto Chiapas (Tapachula), Mexico
  • Puerto Vallarta, Mexico
  • Honolulu, Oahu
View more ports

Ports

Miami, Florida - Kralendijk, Bonaire - Willemstad, Curacao - Cartagena, Colombia - Fuerte Amador, Panama - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Chiapas (Tapachula), Mexico - Puerto Vallarta, Mexico - Honolulu, Oahu - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$8639*

 

N/A

N/A

N/A

$8639*

See Offers

N/A

N/A

N/A

$8639*

See Offers

N/A

N/A

N/A

$8639*

Ports

  • Miami, Florida
  • Port Royal
  • Santa Marta, Colombia
  • Cartagena, Colombia
  • Panama Canal Transit
  • Puntarenas, Costa Rica
  • San Juan Del Sur, Nicaragua
  • Acajutla
  • Puerto Quetzal, Guatemala
  • Huatulco, Mexico
  • Puerto Vallarta, Mexico
  • San Pedro (Los Angeles), California
View more ports

Ports

Miami, Florida - Port Royal - Santa Marta, Colombia - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - San Juan Del Sur, Nicaragua - Acajutla - Puerto Quetzal, Guatemala - Huatulco, Mexico - Puerto Vallarta, Mexico - San Pedro (Los Angeles), California - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$5795*

$9975*

See Offers

N/A

N/A

$5795*

$9975*

 

N/A

$6099*

$6699*

$10499*

See Offers

N/A

N/A

$5795*

$9975*

See Offers

N/A

N/A

$5795*

$9975*

See Offers

N/A

$6099*

$6699*

$10499*

Ports

  • Miami, Florida
  • George Town, Grand Cayman
  • Ocho Rios, Jamaica
  • Kralendijk, Bonaire
  • Willemstad, Curacao
  • Oranjestad, Aruba
  • Cartagena, Colombia
  • Puerto Limon, Costa Rica
  • Panama Canal Transit
  • Panama City, Panama
  • Puntarenas, Costa Rica
  • Puerto Corinto, Nicaragua
  • Puerto Vallarta, Mexico
  • Cabo San Lucas, Mexico
  • Ensenada, Mexico
  • Los Angeles, California
View more ports

Ports

Miami, Florida - George Town, Grand Cayman - Ocho Rios, Jamaica - Kralendijk, Bonaire - Willemstad, Curacao - Oranjestad, Aruba - Cartagena, Colombia - Puerto Limon, Costa Rica - Panama Canal Transit - Panama City, Panama - Puntarenas, Costa Rica - Puerto Corinto, Nicaragua - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - Ensenada, Mexico - Los Angeles, California - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$14599*

See Offers

N/A

N/A

N/A

$14599*

 

N/A

N/A

N/A

$14599*

See Offers

N/A

N/A

N/A

$14599*

See Offers

N/A

N/A

N/A

$14599*

Ports

  • Miami, Florida
  • George Town, Grand Cayman
  • Ocho Rios, Jamaica
  • Kralendijk, Bonaire
  • Willemstad, Curacao
  • Oranjestad, Aruba
  • Cartagena, Colombia
  • Puerto Limon, Costa Rica
  • Panama Canal Transit
  • Panama City, Panama
View more ports

Ports

Miami, Florida - George Town, Grand Cayman - Ocho Rios, Jamaica - Kralendijk, Bonaire - Willemstad, Curacao - Oranjestad, Aruba - Cartagena, Colombia - Puerto Limon, Costa Rica - Panama Canal Transit - Panama City, Panama - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$8499*

See Offers

N/A

N/A

N/A

$8499*

 

N/A

N/A

N/A

$8499*

See Offers

N/A

N/A

N/A

$8499*

See Offers

N/A

N/A

N/A

$8499*

Ports

  • Miami, Florida
  • Progreso (Merida), Mexico
  • Puerto Limon, Costa Rica
  • Panama Canal Transit
  • PANAMA CITY (FUERTE AMADOR), PANAMA
  • Manta, Ecuador
  • Guayaquil, Equador
  • Salaverry (Trujillo), Peru
  • Callao (Lima), Peru
View more ports

Ports

Miami, Florida - Progreso (Merida), Mexico - Puerto Limon, Costa Rica - Panama Canal Transit - PANAMA CITY (FUERTE AMADOR), PANAMA - Manta, Ecuador - Guayaquil, Equador - Salaverry (Trujillo), Peru - Callao (Lima), Peru - View more ports

Ports

  • Miami, Florida
  • Cartagena, Colombia
  • Panama Canal Transit
  • Puntarenas, Costa Rica
  • Puerto Corinto, Nicaragua
  • Puerto Quetzal, Guatemala
  • Acapulco, Mexico
  • Cabo San Lucas, Mexico
  • Hilo, Hawaii
  • Kahului, Maui
  • Honolulu, Oahu
  • Nawiliwili, Kauai
  • Lahaina, Maui
  • Cross International Dateline
  • Fanning Island, Kiribati
  • Rangiroa, French Polynesia
  • Raiatea, French Polynesia
  • Bora Bora, French Polynesia
  • Papeete, Tahiti
View more ports

Ports

Miami, Florida - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Corinto, Nicaragua - Puerto Quetzal, Guatemala - Acapulco, Mexico - Cabo San Lucas, Mexico - Hilo, Hawaii - Kahului, Maui - Honolulu, Oahu - Nawiliwili, Kauai - Lahaina, Maui - Cross International Dateline - Fanning Island, Kiribati - Rangiroa, French Polynesia - Raiatea, French Polynesia - Bora Bora, French Polynesia - Papeete, Tahiti - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

N/A

$25999*

See Offers

N/A

N/A

N/A

$25999*

 

N/A

N/A

N/A

$25999*

See Offers

N/A

N/A

N/A

$25999*

See Offers

N/A

N/A

N/A

$25999*

Ports

  • Miami, Florida
  • Cozumel, Mexico
  • Costa Maya (Mahahual), Mexico
  • Belize City, Belize
  • Coxen Hole, Roatan, Bay Islands, Honduras
  • Puerto Limon, Costa Rica
  • Colon, Panama
  • Panama Canal Transit
  • PANAMA CITY (FUERTE AMADOR), PANAMA
View more ports

Ports

Miami, Florida - Cozumel, Mexico - Costa Maya (Mahahual), Mexico - Belize City, Belize - Coxen Hole, Roatan, Bay Islands, Honduras - Puerto Limon, Costa Rica - Colon, Panama - Panama Canal Transit - PANAMA CITY (FUERTE AMADOR), PANAMA - View more ports

All prices are per person based on double occupancy and do not include port/government fees and gratuities.