Panama Canal, Central America Cruises 136 Panama Canal, Central America Cruises Found

Your Search Clear Selections

Panama Canal, Central America
All Sail Months
Any Length
Any Port
Any Cruise Line
Any Ship

Close

136 Cruises Found

Sort By

Filter By

More
More

Ports

  • Ft. Lauderdale (Port Everglades), Florida
  • Falmouth, Jamaica
  • Cartagena, Colombia
  • Panama Canal (Cruise Into Canal)
  • Colon, Panama
  • Puerto Limon, Costa Rica
  • George Town, Grand Cayman
View More Ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Falmouth, Jamaica - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - George Town, Grand Cayman - View More Ports

Loading itinerary...
Loading reviews...

Top Positive Review

Top Critical Review

Ports

  • San Diego, California
  • Cabo San Lucas, Mexico
  • Puerto Vallarta, Mexico
  • Puerto Quetzal, Guatemala
  • Puntarenas, Costa Rica
  • Panama Canal Transit
  • Colon, Panama
  • Cartagena, Colombia
  • Ft. Lauderdale (Port Everglades), Florida
View More Ports

Ports

San Diego, California - Cabo San Lucas, Mexico - Puerto Vallarta, Mexico - Puerto Quetzal, Guatemala - Puntarenas, Costa Rica - Panama Canal Transit - Colon, Panama - Cartagena, Colombia - Ft. Lauderdale (Port Everglades), Florida - View More Ports

Ports

  • Miami, Florida
  • Cartagena, Colombia
  • Panama Canal Transit
  • Puntarenas, Costa Rica
  • Puerto Corinto, Nicaragua
  • Puerto Quetzal, Guatemala
  • Acapulco, Mexico
  • Cabo San Lucas, Mexico
  • San Pedro (Los Angeles), California
View More Ports

Ports

Miami, Florida - Cartagena, Colombia - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Corinto, Nicaragua - Puerto Quetzal, Guatemala - Acapulco, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - View More Ports

Ports

  • Miami, Florida
  • Cartagena, Colombia
  • Colon, Panama
  • Cruise Gatun Lake And Panama Canal
  • Puerto Limon, Costa Rica
  • Coxen Hole, Roatan, Bay Islands, Honduras
  • Harvest Caye, Belize
  • Costa Maya (Mahahual), Mexico
View More Ports

Ports

Miami, Florida - Cartagena, Colombia - Colon, Panama - Cruise Gatun Lake And Panama Canal - Puerto Limon, Costa Rica - Coxen Hole, Roatan, Bay Islands, Honduras - Harvest Caye, Belize - Costa Maya (Mahahual), Mexico - View More Ports

Ports

  • Ft. Lauderdale (Port Everglades), Florida
  • Princess Cays (Cruise Line Private Island)
  • Charlotte Amalie, St. Thomas
  • Roseau, Dominica
  • St. George's, Grenada
  • Bonaire, Netherlands Special Municipality
  • Willemstad, Curacao
  • George Town, Grand Cayman
  • Cartagena, Colombia
  • Colon, Panama
  • Panama Canal (Cruise Into Canal)
  • Puerto Limon, Costa Rica
  • Falmouth, Jamaica
View More Ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Princess Cays (Cruise Line Private Island) - Charlotte Amalie, St. Thomas - Roseau, Dominica - St. George's, Grenada - Bonaire, Netherlands Special Municipality - Willemstad, Curacao - George Town, Grand Cayman - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - Falmouth, Jamaica - View More Ports

Ports

  • San Pedro (Los Angeles), California
  • Cabo San Lucas, Mexico
  • Acapulco, Mexico
  • Puerto Quetzal, Guatemala
  • San Juan Del Sur, Nicaragua
  • Puntarenas, Costa Rica
  • Panama Canal Transit
  • Cartagena, Colombia
  • Miami, Florida
View More Ports

Ports

San Pedro (Los Angeles), California - Cabo San Lucas, Mexico - Acapulco, Mexico - Puerto Quetzal, Guatemala - San Juan Del Sur, Nicaragua - Puntarenas, Costa Rica - Panama Canal Transit - Cartagena, Colombia - Miami, Florida - View More Ports

Ports

  • Ft. Lauderdale (Port Everglades), Florida
  • Cartagena, Colombia
  • Panama Canal Transit
  • Fuerte Amador, Panama
  • Puntarenas, Costa Rica
  • San Juan Del Sur, Nicaragua
  • Huatulco, Mexico
  • Puerto Vallarta, Mexico
  • San Pedro (Los Angeles), California
View More Ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Cartagena, Colombia - Panama Canal Transit - Fuerte Amador, Panama - Puntarenas, Costa Rica - San Juan Del Sur, Nicaragua - Huatulco, Mexico - Puerto Vallarta, Mexico - San Pedro (Los Angeles), California - View More Ports

Ports

  • Tampa, Florida
  • Cozumel, Mexico
  • Puerto Limon, Costa Rica
  • Cartagena, Colombia
  • Oranjestad, Aruba
  • Willemstad, Curacao
  • Ocho Rios, Jamaica
View More Ports

Ports

Tampa, Florida - Cozumel, Mexico - Puerto Limon, Costa Rica - Cartagena, Colombia - Oranjestad, Aruba - Willemstad, Curacao - Ocho Rios, Jamaica - View More Ports

Loading itinerary...
Loading reviews...

Top Positive Review

Top Critical Review

Sail Date Inside Oceanview Balcony Suite
Dec 01, 2018

Inside

N/A

Oceanview

N/A

Balcony

N/A

Suite

N/A

Dec 02, 2018

Inside

$1249*

expedia.com

Oceanview

$1569*

expedia.com

Balcony

$1869*

expedia.com

Suite

$3620*

directlinecruises.com

Ports

  • San Pedro (Los Angeles), California
  • Huatulco, Mexico
  • Puerto Chiapas (Tapachula), Mexico
  • Puerto Quetzal, Guatemala
  • Cruise Gatun Lake (Inside Panama Canal)
  • Puntarenas, Costa Rica
  • San Juan Del Sur, Nicaragua
  • Manzanillo, Mexico
View More Ports

Ports

San Pedro (Los Angeles), California - Huatulco, Mexico - Puerto Chiapas (Tapachula), Mexico - Puerto Quetzal, Guatemala - Cruise Gatun Lake (Inside Panama Canal) - Puntarenas, Costa Rica - San Juan Del Sur, Nicaragua - Manzanillo, Mexico - View More Ports

Ports

  • San Francisco, California
  • Cabo San Lucas, Mexico
  • San Juan Del Sur, Nicaragua
  • Puntarenas, Costa Rica
  • Fuerte Amador, Panama
  • Panama Canal Transit
  • Cartagena, Colombia
  • Ft. Lauderdale (Port Everglades), Florida
View More Ports

Ports

San Francisco, California - Cabo San Lucas, Mexico - San Juan Del Sur, Nicaragua - Puntarenas, Costa Rica - Fuerte Amador, Panama - Panama Canal Transit - Cartagena, Colombia - Ft. Lauderdale (Port Everglades), Florida - View More Ports

All prices are per person based on double occupancy and do not include port / government fees and gratuities.