Holland America Line to Panama Canal, Central America

Ports

Ft. Lauderdale (Port Everglades), Florida
Half Moon Cay, Bahamas (Private Island)
Willemstad, Curacao
Cartagena, Colombia
Colon, Panama
Panama Canal (Cruise Into Canal)
Puerto Limon, Costa Rica
George Town, Grand Cayman

Ports

Ft. Lauderdale (Port Everglades), Florida - Half Moon Cay, Bahamas (Private Island) - Willemstad, Curacao - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports

12 Night Panama Canal Discovery: Costa Rica & Greater Antilles (Ft. Lauderdale Roundtrip)

Rotterdam L

4.4

(266 Reviews)

2025 sail dates: Oct 26, Dec 07

2026 sail dates: Feb 08, Mar 01

$1219*

$102/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 266 Rotterdam reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1319*	$1919*	$2119*	$3419*
See Offers	$1319*	$1919*	$2119*	$3419*
See Offers	$1319*	$1919*	$2119*	$3419*
See Offers	$1319*	$1919*	$2119*	$3419*
	$1319*	$1919*	$2119*	$3419*
See Offers	$1319*	$1919*	$2119*	$3419*
	$1319*	$1919*	$2119*	$3419*
See Offers	$1319*	$1919*	$2119*	$3419*
	$1219*	$1819*	$2019*	$3319*
See Offers	$1219*	$1819*	$2019*	$3319*
See Offers	$1219*	$1819*	$2019*	$3319*
See Offers	$1219*	$1819*	$2019*	$3319*
See Offers	$1219*	$1819*	$2019*	$3319*
	$1219*	$1819*	$2019*	$3319*
See Offers	$1219*	$1819*	$2019*	$3319*
	$1219*	$1819*	$2019*	$3319*
See Offers	$1219*	$1819*	$2019*	$3319*
	$1719*	$2319*	$2519*	$3869*
See Offers	$1719*	$2319*	$2519*	$3869*
See Offers	$1719*	$2319*	$2519*	$3869*
See Offers	$1719*	$2319*	$2519*	$3869*
See Offers	$1719*	$2319*	$2519*	$3869*
	$1719*	$2319*	$2519*	$3869*
See Offers	$1719*	$2319*	$2519*	$3869*
	$1719*	$2319*	$2519*	$3869*
See Offers	$1719*	$2319*	$2519*	$3869*
	$1679*	$2219*	$2479*	$3979*
See Offers	$1679*	$2219*	$2479*	$3959*
See Offers	$1679*	$2219*	$2479*	$3979*
See Offers	$1679*	$2219*	$2479*	$3979*
See Offers	$1679*	$2219*	$2479*	$3959*
	$1679*	$2219*	$2479*	$3959*
See Offers	$1679*	$2219*	$2479*	$3979*
	$1679*	$2219*	$2479*	$3979*
See Offers	$1679*	$2219*	$2479*	$3979*

Ports

Ft. Lauderdale (Port Everglades), Florida
Willemstad, Curacao
Kralendijk, Bonaire
Oranjestad, Aruba
Half Moon Cay, Bahamas (Private Island)
Cartagena, Colombia
Colon, Panama
Panama Canal (Cruise Into Canal)
Puerto Limon, Costa Rica
George Town, Grand Cayman

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Willemstad, Curacao - Kralendijk, Bonaire - Oranjestad, Aruba - Half Moon Cay, Bahamas (Private Island) - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports

21 Night Southern Caribbean & Panama Canal: Abc Islands (Ft. Lauderdale Roundtrip)

Rotterdam L

4.4

(266 Reviews)

2026 sail dates: Jan 30, Feb 20

$2583*

$123/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 266 Rotterdam reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$2584*	$3384*	$3754*	$5644*
See Offers	$2584*	$3384*	$3754*	$5644*
See Offers	$2584*	$3384*	$3754*	$5644*
See Offers	$2584*	$3384*	$3754*	$5644*
See Offers	$2584*	$3384*	$3754*	$5644*
	$2584*	$3384*	$3754*	$5644*
See Offers	$2584*	$3384*	$3754*	$5644*
	$2584*	$3384*	$3754*	$5644*
See Offers	$2584*	$3384*	$3754*	$5644*
	$2583*	$3423*	$3753*	$5823*
See Offers	$2583*	$3423*	$3753*	$5823*
See Offers	$2583*	$3423*	$3753*	$5823*
See Offers	$2583*	$3423*	$3753*	$5823*
See Offers	$2583*	$3423*	$3753*	$5823*
	$2583*	$3423*	$3753*	$5823*
See Offers	$2583*	$3423*	$3753*	$5823*
	$2583*	$3423*	$3753*	$5823*
See Offers	$2583*	$3423*	$3753*	$5823*

Ports

Ft. Lauderdale (Port Everglades), Florida
Half Moon Cay, Bahamas (Private Island)
Willemstad, Curacao
Cartagena, Colombia
Colon, Panama
Panama Canal (Cruise Into Canal)
Puerto Limon, Costa Rica
George Town, Grand Cayman
Kralendijk, Bonaire
Oranjestad, Aruba

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Half Moon Cay, Bahamas (Private Island) - Willemstad, Curacao - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - George Town, Grand Cayman - Kralendijk, Bonaire - Oranjestad, Aruba - View more ports

21 Night Panama Canal & Southern Caribbean: Abc Islands (Ft. Lauderdale Roundtrip)

Rotterdam L

4.4

(266 Reviews)

2025 sail dates: Oct 26

2026 sail dates: Feb 08, Mar 01

$1935*

$92/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 266 Rotterdam reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1935*	$2665*	$3015*	$4535*
See Offers	$1935*	$2665*	$3015*	$4535*
See Offers	$1935*	$2665*	$3015*	$4535*
See Offers	$1935*	$2665*	$3015*	$4535*
See Offers	$1935*	$2665*	$3015*	$4535*
	$1935*	$2665*	$3015*	$4535*
See Offers	$1935*	$2665*	$3015*	$4535*
	$1935*	$2665*	$3015*	$4535*
See Offers	$1935*	$2665*	$3015*	$4535*
	$2674*	$3514*	$3844*	$5779*
See Offers	$2674*	$3514*	$3844*	$5779*
See Offers	$2674*	$3514*	$3844*	$5779*
See Offers	$2674*	$3514*	$3844*	$5779*
See Offers	$2674*	$3514*	$3844*	$5779*
	$2674*	$3514*	$3844*	$5779*
See Offers	$2674*	$3514*	$3844*	$5779*
	$2674*	$3514*	$3844*	$5779*
See Offers	$2674*	$3514*	$3844*	$5779*
	$2578*	$3418*	$3748*	$5818*
See Offers	$2578*	$3418*	$3748*	$5818*
See Offers	$2578*	$3418*	$3748*	$5818*
See Offers	$2578*	$3418*	$3748*	$5818*
See Offers	$2578*	$3418*	$3748*	$5818*
	$2578*	$3418*	$3748*	$5818*
See Offers	$2578*	$3418*	$3748*	$5818*
	$2578*	$3418*	$3748*	$5818*
See Offers	$2578*	$3418*	$3748*	$5818*

Ports

Buenos Aires, Argentina
Montevideo, Uruguay
Port Stanley, Falkland Islands
Cruise Cape Horn
Cruise Beagle Channel
Cruise Glacier Alley
Ushuaia, Tierra Del Fuego, Argentina
Cruise Strait Of Magellan
Punta Arenas, Chile
Cruise Cockburn Channel
Puerto Montt, Chile
San Antonio, Chile
Coquimbo (La Serena), Chile
General San Martin (Pisco), Peru
Callao (Lima), Peru
Salaverry (Trujillo), Peru
Manta, Ecuador
Fuerte Amador, Panama
Panama Canal Transit
George Town, Grand Cayman
Ft. Lauderdale (Port Everglades), Florida

View more ports

Ports

Buenos Aires, Argentina - Montevideo, Uruguay - Port Stanley, Falkland Islands - Cruise Cape Horn - Cruise Beagle Channel - Cruise Glacier Alley - Ushuaia, Tierra Del Fuego, Argentina - Cruise Strait Of Magellan - Punta Arenas, Chile - Cruise Cockburn Channel - Puerto Montt, Chile - San Antonio, Chile - Coquimbo (La Serena), Chile - General San Martin (Pisco), Peru - Callao (Lima), Peru - Salaverry (Trujillo), Peru - Manta, Ecuador - Fuerte Amador, Panama - Panama Canal Transit - George Town, Grand Cayman - Ft. Lauderdale (Port Everglades), Florida - View more ports

31 Night South America Inca & Panama Canal Discovery (Buenos Aires To Ft. Lauderdale)

Oosterdam M

4.1

(890 Reviews)

2025 sail dates: Mar 05

2026 sail dates: Mar 08

$3289*

$106/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 890 Oosterdam reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$3289*	$3739*	$6439*	$8229*
See Offers	$3289*	$3739*	$6439*	$8229*
See Offers	$3289*	$3739*	$6439*	$8229*
See Offers	$3289*	$3739*	$6439*	$8229*
See Offers	$3289*	$3739*	$6439*	$8229*
	$3289*	$3739*	$6439*	$8229*
See Offers	$3289*	$3739*	$6439*	$8229*
	$3289*	$3739*	$6439*	$8229*
See Offers	$3289*	$3739*	$6439*	$8229*
	$4149*	$4349*	$6349*	$8989*
See Offers	$4149*	$4349*	$6349*	$8989*
See Offers	$4149*	$4349*	$6349*	$8989*
See Offers	$4149*	$4349*	$6349*	$8989*
See Offers	$4149*	$4349*	$6349*	$8989*
	$4149*	$4349*	$6349*	$8989*
See Offers	$4149*	$4349*	$6349*	$8989*
	$4149*	$4349*	$6349*	$8989*
See Offers	$4149*	$4349*	$6349*	$8989*

Ports

Ft. Lauderdale (Port Everglades), Florida
Half Moon Cay, Bahamas (Private Island)
Oranjestad, Aruba
Cartagena, Colombia
Colon, Panama
Panama Canal (Cruise Into Canal)
Puerto Limon, Costa Rica
George Town, Grand Cayman
Willemstad, Curacao
Kralendijk, Bonaire

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Half Moon Cay, Bahamas (Private Island) - Oranjestad, Aruba - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - George Town, Grand Cayman - Willemstad, Curacao - Kralendijk, Bonaire - View more ports

21 Night Panama Canal Sunfarer/Southern Caribbean Seafarer (Ft. Lauderdale Roundtrip)

Rotterdam L

4.4

(266 Reviews)

2025 sail dates: Feb 23

$2019*

$96/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 266 Rotterdam reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$2019*	$3099*	$4359*	$5889*
See Offers	$2594*	$3674*	$4934*	$6464*
See Offers	$2019*	$3099*	$4359*	$5889*
See Offers	$2019*	$3099*	$4359*	$5889*
See Offers	$2594*	$3674*	$4934*	$6464*
	$2594*	$3674*	$4934*	$6464*
See Offers	$2019*	$3099*	$4359*	$5889*
	$2019*	$3099*	$4359*	$5889*
See Offers	$2019*	$3099*	$4359*	$5889*

Ports

Ft. Lauderdale (Port Everglades), Florida
Half Moon Cay, Bahamas (Private Island)
Oranjestad, Aruba
Cartagena, Colombia
Panama Canal (Cruise Into Canal)
Colon, Panama
Puerto Limon, Costa Rica
Montego Bay, Jamaica

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Half Moon Cay, Bahamas (Private Island) - Oranjestad, Aruba - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - Montego Bay, Jamaica - View more ports

12 Night Panama Canal Sunfarer (Ft. Lauderdale Roundtrip)

Rotterdam L

4.4

(266 Reviews)

2025 sail dates: Feb 02

$1499*

$125/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 266 Rotterdam reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1499*	N/A	N/A	$4439*
See Offers	$2004*	N/A	N/A	$4944*
See Offers	$1499*	N/A	N/A	$4439*
See Offers	$1499*	N/A	N/A	$4439*
See Offers	$2004*	N/A	N/A	$4944*
	$2004*	N/A	N/A	$4944*
See Offers	$1499*	N/A	N/A	$4439*
	$1499*	N/A	N/A	$4439*
See Offers	$1499*	N/A	N/A	$4439*

Ports

Ft. Lauderdale (Port Everglades), Florida
Half Moon Cay, Bahamas (Private Island)
Oranjestad, Aruba
Cartagena, Colombia
Panama Canal (Cruise Into Canal)
Colon, Panama
Puerto Limon, Costa Rica
George Town, Grand Cayman

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Half Moon Cay, Bahamas (Private Island) - Oranjestad, Aruba - Cartagena, Colombia - Panama Canal (Cruise Into Canal) - Colon, Panama - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports

12 Night Panama Canal Sunfarer (Ft. Lauderdale Roundtrip)

Rotterdam L

4.4

(266 Reviews)

2025 sail dates: Feb 23

$1299*

$108/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 266 Rotterdam reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1299*	$2099*	$3399*	$4199*
See Offers	$789*	$1589*	$2254*	$3689*
See Offers	$1299*	$2099*	$3399*	$4199*
See Offers	$1234*	$1954*	$2764*	$3844*
See Offers	$789*	$1589*	$2254*	$3689*
	$789*	$1589*	$2254*	$3689*
See Offers	$1234*	$1954*	$3124*	$3844*
	$1234*	$1954*	$3124*	$3844*
See Offers	$1234*	$1954*	$2764*	$3844*

Ports

Ft. Lauderdale (Port Everglades), Florida
Half Moon Cay, Bahamas (Private Island)
Oranjestad, Aruba
Cartagena, Colombia
Colon, Panama
Panama Canal (Cruise Into Canal)
Puerto Limon, Costa Rica
Ocho Rios, Jamaica

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Half Moon Cay, Bahamas (Private Island) - Oranjestad, Aruba - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - Ocho Rios, Jamaica - View more ports

12 Night Panama Canal Sunfarer (Ft. Lauderdale Roundtrip)

Rotterdam L

4.4

(266 Reviews)

2025 sail dates: Mar 16

$1179*

$98/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 266 Rotterdam reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1179*	$1849*	$2449*	$3399*
See Offers	$1199*	$1899*	$2499*	$3499*
See Offers	$1179*	$1849*	$2449*	$3399*
See Offers	$1199*	$1899*	$2499*	$3499*
See Offers	$1199*	$1899*	$2499*	$3499*
	$1199*	$1899*	$2499*	$3499*
See Offers	$1199*	$1899*	$2499*	$3499*
	$1199*	$1899*	$2499*	$3499*
See Offers	$1199*	$1899*	$2499*	$3499*

Ports

Ft. Lauderdale (Port Everglades), Florida
Half Moon Cay, Bahamas (Private Island)
Oranjestad, Aruba
Cartagena, Colombia
Colon, Panama
Panama Canal (Cruise Into Canal)
Puerto Limon, Costa Rica
Falmouth, Jamaica
Willemstad, Curacao
Kralendijk, Bonaire

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Half Moon Cay, Bahamas (Private Island) - Oranjestad, Aruba - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - Falmouth, Jamaica - Willemstad, Curacao - Kralendijk, Bonaire - View more ports

21 Night Panama Canal & Southern Caribbean: Abc Islands (Ft. Lauderdale Roundtrip)

Rotterdam L

4.4

(266 Reviews)

2025 sail dates: Nov 16

$1818*

$87/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 266 Rotterdam reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1818*	$2588*	$2938*	$4458*
See Offers	$1818*	$2588*	$2938*	$4458*
See Offers	$1818*	$2588*	$2938*	$4458*
See Offers	$1818*	$2588*	$2938*	$4458*
See Offers	$1818*	$2588*	$2938*	$4458*
	$1818*	$2588*	$2938*	$4458*
See Offers	$1818*	$2588*	$2938*	$4458*
	$1818*	$2588*	$2938*	$4458*
See Offers	$1818*	$2588*	$2938*	$4458*

Ports

Ft. Lauderdale (Port Everglades), Florida
Half Moon Cay, Bahamas (Private Island)
CABO ROJO, DOMINICAN REPUBLIC
Cartagena, Colombia
Cruise Gatun Lake And Panama Canal
Cruise Gatun Lake (Inside Panama Canal)
Colon, Panama
Enter Panama Canal At Cristobal
Exit Panama Canal At Cristobal
Puerto Limon, Costa Rica
George Town, Grand Cayman

View more ports

Ports

Ft. Lauderdale (Port Everglades), Florida - Half Moon Cay, Bahamas (Private Island) - CABO ROJO, DOMINICAN REPUBLIC - Cartagena, Colombia - Cruise Gatun Lake And Panama Canal - Cruise Gatun Lake (Inside Panama Canal) - Colon, Panama - Enter Panama Canal At Cristobal - Exit Panama Canal At Cristobal - Puerto Limon, Costa Rica - George Town, Grand Cayman - View more ports

12 Night Panama Canal Sunfarer Holiday (Ft. Lauderdale Roundtrip)

Rotterdam L

4.4

(266 Reviews)

2024 sail dates: Dec 29

$1299*

$108/night*

Inside

View Deal

Compare

Loading itinerary...

Loading reviews...

Read all 266 Rotterdam reviews

Compare Prices

Bonus Offers	Inside	Oceanview	Balcony	Suite
	$1299*	$1749*	N/A	N/A
See Offers	$1154*	$1604*	N/A	N/A
See Offers	$1299*	$1749*	$2559*	N/A
See Offers	$1154*	$1604*	N/A	N/A
	$1154*	$1604*	N/A	N/A
See Offers	$1299*	$1749*	N/A	N/A
See Offers	$1299*	$1749*	$2559*	N/A

Holland America Line Cruises to Panama Canal, Central America 62 cruises on Holland America Line found

Your search Clear selections

62 cruises found

Sort by

Filter by

More popular destinations for Holland America Line

More popular cruise lines that sail to Panama Canal, Central America

More popular departure ports with sailings to Panama Canal, Central America