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Cruises on American Cruise Line 162 cruises on American Cruise Line found

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162 cruises found

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Ports

  • Jacksonville, Florida
  • Amelia Island, Florida
  • JEKYLL ISLAND, GEORGIA
  • Savannah, Georgia
  • HILTON HEAD ISLAND, SOUTH CAROLINA
  • BEAUFORT, SOUTH CAROLINA
  • Charleston, South Carolina
View more ports

Ports

Jacksonville, Florida - Amelia Island, Florida - JEKYLL ISLAND, GEORGIA - Savannah, Georgia - HILTON HEAD ISLAND, SOUTH CAROLINA - BEAUFORT, SOUTH CAROLINA - Charleston, South Carolina - View more ports

American Independence S

4.6
(8 Reviews)

2024 sail dates:

2025 sail dates: Apr 05,

$4110*
$587/night*
Oceanview
View Deal
$4110* luxuryonly.com $4110* dreamvacations.com
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Top critical review

Read all 8 American Independence reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

$4110*

$4990*

$6795*

 

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$4110*

$4990*

$6795*

 

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$4425*

$5365*

$7295*

 

N/A

$4425*

$5365*

$7295*

Ports

  • ST. PETERSBURG, FLORIDA
  • FORT MYERS, FLORIDA
  • Key West, Florida
  • MARCO ISLAND, FLORIDA
  • PUNTA GORDA, FLORIDA
View more ports

Ports

ST. PETERSBURG, FLORIDA - FORT MYERS, FLORIDA - Key West, Florida - MARCO ISLAND, FLORIDA - PUNTA GORDA, FLORIDA - View more ports

American Legend S

2024 sail dates:

2025 sail dates: Jan 06, Jan 13, Jan 20, Jan 27, Feb 03, Feb 10, Feb 17, More

$6995*
$999/night*
Balcony
View Deal
$6995* luxuryonly.com $6995* dreamvacations.com
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Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

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$6995*

$9315*

 

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Ports

  • Memphis, Tennessee
  • RIVER CRUISING
  • Vicksburg, Mississippi
  • Natchez, Mississippi
  • St. Francisville, Louisiana
  • Baton Rouge, Louisiana
  • Houmas House Plantation, Louisiana
  • New Orleans, Louisiana
View more ports

Ports

Memphis, Tennessee - RIVER CRUISING - Vicksburg, Mississippi - Natchez, Mississippi - St. Francisville, Louisiana - Baton Rouge, Louisiana - Houmas House Plantation, Louisiana - New Orleans, Louisiana - View more ports

American Melody S

5.0
(8 Reviews)

2024 sail dates:

2025 sail dates: Apr 05, Apr 19, May 03, May 17, More

$5275*
$754/night*
Balcony
View Deal
$5275* luxuryonly.com $5275* dreamvacations.com
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Read all 8 American Melody reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

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$5495*

$7790*

 

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$5495*

$7790*

 

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$5275*

$7295*

Ports

  • ST. PETERSBURG, FLORIDA
  • FORT MYERS, FLORIDA
  • Key West, Florida
  • MARCO ISLAND, FLORIDA
  • PUNTA GORDA, FLORIDA
View more ports

Ports

ST. PETERSBURG, FLORIDA - FORT MYERS, FLORIDA - Key West, Florida - MARCO ISLAND, FLORIDA - PUNTA GORDA, FLORIDA - View more ports

American Glory S

5.0
(1 Reviews)

2024 sail dates:

2025 sail dates: Jan 11, Jan 18, Jan 25, Feb 08, Feb 15, Feb 22, Mar 01, Mar 08, Mar 15, More

$5990*
$856/night*
Oceanview
View Deal
$5990* luxuryonly.com $5990* dreamvacations.com
Loading itinerary...
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Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

$5990*

$6995*

$9315*

 

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$5990*

$6995*

$9315*

 

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Ports

  • Jacksonville, Florida
  • Amelia Island, Florida
  • JEKYLL ISLAND, GEORGIA
  • Savannah, Georgia
  • HILTON HEAD ISLAND, SOUTH CAROLINA
  • BEAUFORT, SOUTH CAROLINA
  • Charleston, South Carolina
View more ports

Ports

Jacksonville, Florida - Amelia Island, Florida - JEKYLL ISLAND, GEORGIA - Savannah, Georgia - HILTON HEAD ISLAND, SOUTH CAROLINA - BEAUFORT, SOUTH CAROLINA - Charleston, South Carolina - View more ports

American Liberty XL

5.0
(1 Reviews)

2024 sail dates: Dec 28

2025 sail dates: Feb 15, Mar 01, Mar 15, Mar 29, Apr 12, May 10, Nov 15, Nov 29, Dec 13, Dec 27, More

$6245*
$892/night*
Balcony
View Deal
$6245* luxuryonly.com $6245* dreamvacations.com
Loading itinerary...
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Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

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$6575*

$8755*

 

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Ports

  • Clarkston, Washington
  • CRUISE SNAKE RIVER, PACIFIC NORTHWEST, USA
  • Pendleton, Oregon
  • THE DALLES, OREGON
  • Cruise Columbia River
  • Mount St. Helens, Washington
  • Astoria, Oregon
  • Portland, Oregon
View more ports

Ports

Clarkston, Washington - CRUISE SNAKE RIVER, PACIFIC NORTHWEST, USA - Pendleton, Oregon - THE DALLES, OREGON - Cruise Columbia River - Mount St. Helens, Washington - Astoria, Oregon - Portland, Oregon - View more ports

American Harmony S

5.0
(6 Reviews)

2024 sail dates:

2025 sail dates: May 03, May 31, Jun 14, Jun 28, Jul 12, Jul 26, Aug 09, Aug 23, Sep 20, Oct 04, Oct 18, Nov 01, More

$5595*
$799/night*
Balcony
View Deal
$5595* luxuryonly.com $5595* dreamvacations.com
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Top positive review

Top critical review

Read all 6 American Harmony reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

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$5595*

$7890*

 

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$5595*

$7890*

 

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$5955*

$8385*

 

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$6355*

$8785*

 

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$9780*

 

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$8985*

 

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$5855*

$8285*

 

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$9285*

Ports

  • Charleston, South Carolina
  • BEAUFORT, SOUTH CAROLINA
  • HILTON HEAD ISLAND, SOUTH CAROLINA
  • Savannah, Georgia
  • JEKYLL ISLAND, GEORGIA
  • Amelia Island, Florida
  • Jacksonville, Florida
View more ports

Ports

Charleston, South Carolina - BEAUFORT, SOUTH CAROLINA - HILTON HEAD ISLAND, SOUTH CAROLINA - Savannah, Georgia - JEKYLL ISLAND, GEORGIA - Amelia Island, Florida - Jacksonville, Florida - View more ports

American Eagle S

5.0
(2 Reviews)

2024 sail dates: Dec 29

2025 sail dates: Mar 31, Apr 14, Apr 28, May 12, Dec 12, More

$4880*
$697/night*
Oceanview
View Deal
$4880* luxuryonly.com $4880* dreamvacations.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

$5630*

$6575*

$8755*

 

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$5630*

$6575*

$8755*

 

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$4880*

$5825*

$8005*

 

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$4880*

$5825*

$8005*

 

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$5630*

$6575*

$8755*

 

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$5630*

$6575*

$8755*

 

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$5240*

$6245*

$8565*

 

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$5240*

$6245*

$8565*

 

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$5990*

$6995*

$9315*

 

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$6995*

$9315*

 

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$6995*

$9315*

 

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$6995*

$9315*

 

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$5630*

$6575*

$8755*

 

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$5630*

$6575*

$8755*

 

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$5630*

$6575*

$8755*

 

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$5630*

$6575*

$8755*

 

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$5990*

$6995*

$9315*

 

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$6995*

$9315*

 

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$6995*

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$6995*

$9315*

 

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$5990*

$6995*

$9315*

 

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$5990*

$6995*

$9315*

Ports

  • Memphis, Tennessee
  • RIVER CRUISING
  • Vicksburg, Mississippi
  • Natchez, Mississippi
  • St. Francisville, Louisiana
  • Baton Rouge, Louisiana
  • Houmas House Plantation, Louisiana
  • New Orleans, Louisiana
View more ports

Ports

Memphis, Tennessee - RIVER CRUISING - Vicksburg, Mississippi - Natchez, Mississippi - St. Francisville, Louisiana - Baton Rouge, Louisiana - Houmas House Plantation, Louisiana - New Orleans, Louisiana - View more ports

American Symphony S

4.2
(4 Reviews)

2024 sail dates: Dec 30

2025 sail dates: Jul 02, Aug 27, Nov 05, More

$4415*
$631/night*
Balcony
View Deal
$4415* luxuryonly.com $4415* dreamvacations.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 4 American Symphony reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$5275*

$7295*

 

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N/A

$5275*

$7295*

 

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$4415*

$6300*

 

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$4415*

$6300*

 

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$6300*

 

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$4415*

$6300*

 

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$4915*

$6800*

 

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$4915*

$6800*

 

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$5275*

$7295*

 

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$5275*

$7295*

 

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$5995*

$8290*

 

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$8290*

 

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$7295*

 

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$7295*

Ports

  • Charleston, South Carolina
  • BEAUFORT, SOUTH CAROLINA
  • HILTON HEAD ISLAND, SOUTH CAROLINA
  • Savannah, Georgia
  • JEKYLL ISLAND, GEORGIA
  • Amelia Island, Florida
  • Jacksonville, Florida
View more ports

Ports

Charleston, South Carolina - BEAUFORT, SOUTH CAROLINA - HILTON HEAD ISLAND, SOUTH CAROLINA - Savannah, Georgia - JEKYLL ISLAND, GEORGIA - Amelia Island, Florida - Jacksonville, Florida - View more ports

American Independence S

4.6
(8 Reviews)

2024 sail dates:

2025 sail dates: Apr 12,

$4110*
$587/night*
Oceanview
View Deal
$4110* luxuryonly.com $4110* dreamvacations.com
Loading itinerary...
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Top positive review

Top critical review

Read all 8 American Independence reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

$4110*

$4990*

$6795*

 

N/A

$4110*

$4990*

$6795*

 

N/A

$4625*

$5565*

$7495*

 

N/A

$4625*

$5565*

$7495*

Ports

  • New Orleans, Louisiana
  • Houmas House Plantation, Louisiana
  • Baton Rouge, Louisiana
  • St. Francisville, Louisiana
  • Natchez, Mississippi
  • Vicksburg, Mississippi
  • RIVER CRUISING
  • Memphis, Tennessee
View more ports

Ports

New Orleans, Louisiana - Houmas House Plantation, Louisiana - Baton Rouge, Louisiana - St. Francisville, Louisiana - Natchez, Mississippi - Vicksburg, Mississippi - RIVER CRUISING - Memphis, Tennessee - View more ports

American Symphony S

4.2
(4 Reviews)

2024 sail dates:

2025 sail dates: Sep 03,

$4415*
$631/night*
Balcony
View Deal
$4415* luxuryonly.com $4415* dreamvacations.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 4 American Symphony reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$4415*

$6300*

 

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N/A

$4415*

$6300*

 

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$5275*

$7295*

 

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$5275*

$7295*

 

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$8290*

 

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$5995*

$8290*

 

N/A

N/A

$5995*

$8290*

 

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$5995*

$8290*

 

N/A

N/A

$5995*

$8290*

 

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$5275*

$7295*

1 - 10 of 162

All prices are per person based on double occupancy and do not include port/government fees and gratuities.

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