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Cruises on American Cruise Line 160 cruises on American Cruise Line found

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Ports

  • Portland, Oregon
  • HAYDEN ISLAND, PORTLAND, OREGON
  • Astoria, Oregon
  • Mount St. Helens, Washington
  • Cruise Columbia River
  • THE DALLES, OREGON
  • Pendleton, Oregon
  • CRUISE SNAKE RIVER, PACIFIC NORTHWEST, USA
  • Clarkston, Washington
View more ports

Ports

Portland, Oregon - HAYDEN ISLAND, PORTLAND, OREGON - Astoria, Oregon - Mount St. Helens, Washington - Cruise Columbia River - THE DALLES, OREGON - Pendleton, Oregon - CRUISE SNAKE RIVER, PACIFIC NORTHWEST, USA - Clarkston, Washington - View more ports

American Harmony S

5.0
(6 Reviews)

2024 sail dates:

2025 sail dates: Apr 26, May 10, May 24, Jun 07, Jun 21, Jul 05, Jul 19, Aug 02, Aug 16, Aug 30, Sep 13, Sep 27, Oct 11, Oct 25, More

$5995*
$856/night*
Balcony
View Deal
$5995* luxuryonly.com $5995* dreamvacations.com
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Top positive review

Top critical review

Read all 6 American Harmony reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

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Ports

  • Memphis, Tennessee
  • RIVER CRUISING
  • Vicksburg, Mississippi
  • Natchez, Mississippi
  • St. Francisville, Louisiana
  • Baton Rouge, Louisiana
  • Houmas House Plantation, Louisiana
  • New Orleans, Louisiana
View more ports

Ports

Memphis, Tennessee - RIVER CRUISING - Vicksburg, Mississippi - Natchez, Mississippi - St. Francisville, Louisiana - Baton Rouge, Louisiana - Houmas House Plantation, Louisiana - New Orleans, Louisiana - View more ports

American Symphony S

4.2
(4 Reviews)

2024 sail dates: Dec 07, Dec 30

2025 sail dates: Jul 02, Jul 16, Nov 05, More

$4915*
$702/night*
Balcony
View Deal
$4915* luxuryonly.com $4915* dreamvacations.com
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Top positive review

Top critical review

Read all 4 American Symphony reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

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$5275*

$7295*

 

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Ports

  • New Orleans, Louisiana
  • OAK ALLEY PLANTATION, VACHERIE, LOUISIANA
  • Baton Rouge, Louisiana
  • Natchez, Mississippi
  • St. Francisville, Louisiana
View more ports

Ports

New Orleans, Louisiana - OAK ALLEY PLANTATION, VACHERIE, LOUISIANA - Baton Rouge, Louisiana - Natchez, Mississippi - St. Francisville, Louisiana - View more ports

American Melody S

5.0
(8 Reviews)

2024 sail dates:

2025 sail dates: Mar 11, Mar 17, Mar 23,

$4255*
$709/night*
Balcony
View Deal
$4255* luxuryonly.com $4255* dreamvacations.com
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Top positive review

Top critical review

Read all 8 American Melody reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

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$4565*

$6315*

 

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Ports

  • Charleston, South Carolina
  • BEAUFORT, SOUTH CAROLINA
  • HILTON HEAD ISLAND, SOUTH CAROLINA
  • Savannah, Georgia
  • JEKYLL ISLAND, GEORGIA
  • Amelia Island, Florida
  • Jacksonville, Florida
View more ports

Ports

Charleston, South Carolina - BEAUFORT, SOUTH CAROLINA - HILTON HEAD ISLAND, SOUTH CAROLINA - Savannah, Georgia - JEKYLL ISLAND, GEORGIA - Amelia Island, Florida - Jacksonville, Florida - View more ports

American Liberty XL

5.0
(1 Reviews)

2024 sail dates: Dec 07, Dec 21

2025 sail dates: Feb 08, Feb 22, Mar 08, Mar 22, Apr 05, Apr 19, May 03, May 17, Nov 22, Dec 06, Dec 20 More

$6575*
$939/night*
Balcony
View Deal
$6575* luxuryonly.com $6575* dreamvacations.com
Loading itinerary...
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Partners Bonus Offers Inside Oceanview Balcony Suite
 

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$8755*

 

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Ports

  • ST. PETERSBURG, FLORIDA
  • MARCO ISLAND, FLORIDA
  • Key West, Florida
  • PUNTA GORDA, FLORIDA
View more ports

Ports

ST. PETERSBURG, FLORIDA - MARCO ISLAND, FLORIDA - Key West, Florida - PUNTA GORDA, FLORIDA - View more ports

American Glory S

5.0
(1 Reviews)

2024 sail dates:

2025 sail dates: Feb 01

$5630*
$804/night*
Oceanview
View Deal
$5630* luxuryonly.com $5630* dreamvacations.com
Loading itinerary...
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Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

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$6350*

$7415*

$9875*

 

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Ports

  • Jacksonville, Florida
  • Amelia Island, Florida
  • JEKYLL ISLAND, GEORGIA
  • Savannah, Georgia
  • HILTON HEAD ISLAND, SOUTH CAROLINA
  • BEAUFORT, SOUTH CAROLINA
  • Charleston, South Carolina
View more ports

Ports

Jacksonville, Florida - Amelia Island, Florida - JEKYLL ISLAND, GEORGIA - Savannah, Georgia - HILTON HEAD ISLAND, SOUTH CAROLINA - BEAUFORT, SOUTH CAROLINA - Charleston, South Carolina - View more ports

American Eagle S

5.0
(2 Reviews)

2024 sail dates: Dec 08, Dec 22

2025 sail dates: Mar 24, Apr 07, Apr 21, May 05, Dec 05, More

$5630*
$804/night*
Oceanview
View Deal
$5630* luxuryonly.com $5630* dreamvacations.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

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$5630*

$6575*

$8755*

 

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Ports

  • ST. PETERSBURG, FLORIDA
  • FORT MYERS, FLORIDA
  • Key West, Florida
  • MARCO ISLAND, FLORIDA
  • PUNTA GORDA, FLORIDA
View more ports

Ports

ST. PETERSBURG, FLORIDA - FORT MYERS, FLORIDA - Key West, Florida - MARCO ISLAND, FLORIDA - PUNTA GORDA, FLORIDA - View more ports

American Legend S

2024 sail dates: Dec 09, Dec 16, Dec 23, Dec 30 More

2025 sail dates: Jan 13, Jan 20, Jan 27, Feb 03, Feb 10, Feb 17, More

$6995*
$999/night*
Balcony
View Deal
$6995* luxuryonly.com $6995* dreamvacations.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

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$9315*

 

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Ports

  • Charleston, South Carolina
  • BEAUFORT, SOUTH CAROLINA
  • HILTON HEAD ISLAND, SOUTH CAROLINA
  • Savannah, Georgia
  • JEKYLL ISLAND, GEORGIA
  • Amelia Island, Florida
  • Jacksonville, Florida
View more ports

Ports

Charleston, South Carolina - BEAUFORT, SOUTH CAROLINA - HILTON HEAD ISLAND, SOUTH CAROLINA - Savannah, Georgia - JEKYLL ISLAND, GEORGIA - Amelia Island, Florida - Jacksonville, Florida - View more ports

American Independence S

4.6
(8 Reviews)

2024 sail dates:

2025 sail dates: Apr 12,

$4610*
$659/night*
Oceanview
View Deal
$4610* luxuryonly.com $4610* dreamvacations.com
Loading itinerary...
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Top positive review

Top critical review

Read all 8 American Independence reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

$4610*

$5490*

$7295*

 

N/A

$4610*

$5490*

$7295*

 

N/A

$4925*

$5865*

$7795*

 

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$4925*

$5865*

$7795*

Ports

  • Clarkston, Washington
  • CRUISE SNAKE RIVER, PACIFIC NORTHWEST, USA
  • Pendleton, Oregon
  • THE DALLES, OREGON
  • Cruise Columbia River
  • Mount St. Helens, Washington
  • Astoria, Oregon
  • Portland, Oregon
View more ports

Ports

Clarkston, Washington - CRUISE SNAKE RIVER, PACIFIC NORTHWEST, USA - Pendleton, Oregon - THE DALLES, OREGON - Cruise Columbia River - Mount St. Helens, Washington - Astoria, Oregon - Portland, Oregon - View more ports

American Harmony S

5.0
(6 Reviews)

2024 sail dates:

2025 sail dates: Apr 19, May 03, May 17, May 31, Jun 14, Jun 28, Jul 12, Jul 26, Aug 09, Aug 23, Sep 20, Oct 04, Oct 18, Nov 01, More

$5995*
$856/night*
Balcony
View Deal
$5995* luxuryonly.com $5995* dreamvacations.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 6 American Harmony reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

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N/A

$5995*

$8290*

 

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Ports

  • Jacksonville, Florida
  • Amelia Island, Florida
  • JEKYLL ISLAND, GEORGIA
  • Savannah, Georgia
  • HILTON HEAD ISLAND, SOUTH CAROLINA
  • BEAUFORT, SOUTH CAROLINA
  • Charleston, South Carolina
View more ports

Ports

Jacksonville, Florida - Amelia Island, Florida - JEKYLL ISLAND, GEORGIA - Savannah, Georgia - HILTON HEAD ISLAND, SOUTH CAROLINA - BEAUFORT, SOUTH CAROLINA - Charleston, South Carolina - View more ports

American Liberty XL

5.0
(1 Reviews)

2024 sail dates: Dec 14, Dec 28

2025 sail dates: Feb 15, Mar 01, Mar 15, Mar 29, Apr 12, Apr 26, May 10, Nov 15, Nov 29, Dec 27, More

$6575*
$939/night*
Balcony
View Deal
$6575* luxuryonly.com $6575* dreamvacations.com
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Partners Bonus Offers Inside Oceanview Balcony Suite
 

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61 - 70 of 160

All prices are per person based on double occupancy and do not include port/government fees and gratuities.

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