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American Cruise Line Cruises to River Cruises - United States 125 cruises on American Cruise Line found

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Ports

  • Portland, Oregon
  • HAYDEN ISLAND, PORTLAND, OREGON
  • Astoria, Oregon
  • Mount St. Helens, Washington
  • Cruise Columbia River
  • THE DALLES, OREGON
  • Pendleton, Oregon
  • CRUISE SNAKE RIVER, PACIFIC NORTHWEST, USA
  • Clarkston, Washington
View more ports

Ports

Portland, Oregon - HAYDEN ISLAND, PORTLAND, OREGON - Astoria, Oregon - Mount St. Helens, Washington - Cruise Columbia River - THE DALLES, OREGON - Pendleton, Oregon - CRUISE SNAKE RIVER, PACIFIC NORTHWEST, USA - Clarkston, Washington - View more ports

American West S

5.0
(1 Reviews)

2025 sail dates: May 05, Jun 02, Jun 16, Jun 30, Jul 14, Jul 28, Aug 11, Aug 25, Sep 08, Sep 22, Oct 06 More

$4925*
$704/night*
Oceanview
View Deal
$4925* dreamvacations.com $4925* luxuryonly.com
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Ports

  • Chattanooga, Tennessee
  • Decatur, Alabama
  • Florence, Alabama
  • Savannah, Tennessee
  • Paducah, Kentucky
  • CLARKSVILLE, TENNESSEE
  • Nashville, Tennessee
View more ports

Ports

Chattanooga, Tennessee - Decatur, Alabama - Florence, Alabama - Savannah, Tennessee - Paducah, Kentucky - CLARKSVILLE, TENNESSEE - Nashville, Tennessee - View more ports

American Symphony S

4.2
(4 Reviews)

2025 sail dates: May 07, May 21, Jun 18, Jul 30, Sep 24, Oct 08, Oct 22, More

$4775*
$682/night*
Balcony
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$4775* dreamvacations.com $4775* luxuryonly.com
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Read all 4 American Symphony reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

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$5275*

$7295*

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$4915*

$6800*

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Ports

  • Baltimore, Maryland
  • Yorktown, Virginia
  • CRISFIELD, MARYLAND
  • CAMBRIDGE, MARYLAND
  • ST. MICHAELS, MARYLAND
  • ANNAPOLIS, MARYLAND
View more ports

Ports

Baltimore, Maryland - Yorktown, Virginia - CRISFIELD, MARYLAND - CAMBRIDGE, MARYLAND - ST. MICHAELS, MARYLAND - ANNAPOLIS, MARYLAND - View more ports

American Star S

4.5
(9 Reviews)

2025 sail dates:

$4610*
$659/night*
Oceanview
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$4610* dreamvacations.com $4610* luxuryonly.com
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Read all 9 American Star reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

$4610*

$5490*

$7295*

See Offers

N/A

$4610*

$5490*

$7295*

Ports

  • Seattle, Washington
  • ANACORTES, WASHINGTON
  • FRIDAY HARBOR, SAN JUAN ISLAND, WASHINGTON
  • Cruise Inside Passage, Alaska
  • Ketchikan, Alaska
  • Wrangell, Alaska
  • PETERSBURG, ALASKA
  • Cruise Tracy Arm Fjord, Alaska
  • Cruise Glacier Bay
  • Haines, Alaska
  • Skagway, Alaska
  • Juneau, Alaska
View more ports

Ports

Seattle, Washington - ANACORTES, WASHINGTON - FRIDAY HARBOR, SAN JUAN ISLAND, WASHINGTON - Cruise Inside Passage, Alaska - Ketchikan, Alaska - Wrangell, Alaska - PETERSBURG, ALASKA - Cruise Tracy Arm Fjord, Alaska - Cruise Glacier Bay - Haines, Alaska - Skagway, Alaska - Juneau, Alaska - View more ports

American Constitution XL

5.0
(4 Reviews)

2025 sail dates: Sep 07

2026 sail dates: May 09

$9810*
$701/night*
Oceanview
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$9810* dreamvacations.com $9810* luxuryonly.com
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Read all 4 American Constitution reviews

Ports

  • Seattle, Washington
  • ANACORTES, WASHINGTON
  • FRIDAY HARBOR, SAN JUAN ISLAND, WASHINGTON
  • Victoria, British Columbia
  • PORT TOWNSEND, WASHINGTON
  • POULSBO, WA
View more ports

Ports

Seattle, Washington - ANACORTES, WASHINGTON - FRIDAY HARBOR, SAN JUAN ISLAND, WASHINGTON - Victoria, British Columbia - PORT TOWNSEND, WASHINGTON - POULSBO, WA - View more ports

American Spirit S

4.7
(11 Reviews)

2025 sail dates:

$4925*
$704/night*
Oceanview
View Deal
$4925* dreamvacations.com $4925* luxuryonly.com
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Read all 11 American Spirit reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

$4925*

$5865*

$7795*

See Offers

N/A

$4925*

$5865*

$7795*

Ports

  • Clarkston, Washington
  • CRUISE SNAKE RIVER, PACIFIC NORTHWEST, USA
  • Pendleton, Oregon
  • THE DALLES, OREGON
  • Cruise Columbia River
  • Mount St. Helens, Washington
  • Astoria, Oregon
  • Portland, Oregon
View more ports

Ports

Clarkston, Washington - CRUISE SNAKE RIVER, PACIFIC NORTHWEST, USA - Pendleton, Oregon - THE DALLES, OREGON - Cruise Columbia River - Mount St. Helens, Washington - Astoria, Oregon - Portland, Oregon - View more ports

American West S

5.0
(1 Reviews)

2025 sail dates: May 12, Jun 09, Jun 23, Jul 07, Jul 21, Aug 04, Aug 18, Sep 01, Sep 15, Sep 29, Oct 13 More

$4925*
$704/night*
Oceanview
View Deal
$4925* dreamvacations.com $4925* luxuryonly.com
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Ports

  • Seattle, Washington
  • ANACORTES, WASHINGTON
  • FRIDAY HARBOR, SAN JUAN ISLAND, WASHINGTON
  • CRUISE SAN JUAN ISLANDS
  • Victoria, British Columbia
  • PORT TOWNSEND, WASHINGTON
  • POULSBO, WA
View more ports

Ports

Seattle, Washington - ANACORTES, WASHINGTON - FRIDAY HARBOR, SAN JUAN ISLAND, WASHINGTON - CRUISE SAN JUAN ISLANDS - Victoria, British Columbia - PORT TOWNSEND, WASHINGTON - POULSBO, WA - View more ports

American Spirit S

4.7
(11 Reviews)

2025 sail dates: May 17, May 24, May 31, Jun 07, Jun 14, Jun 21, Jun 28, Jul 05, Jul 12, Jul 19, Jul 26, Aug 02, Aug 09, Aug 16, Aug 23, Aug 30, Sep 06, Sep 13, Sep 20 More

2026 sail dates: Jun 06, Jun 13, Jun 20, Jun 27, Jul 04, Jul 11, Jul 18, Jul 25, Aug 01, Aug 08, Aug 15, Aug 22, Sep 05, Sep 12, Sep 19, More

$4925*
$704/night*
Oceanview
View Deal
$4925* dreamvacations.com $4925* luxuryonly.com
Loading itinerary...
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Top positive review

Top critical review

Read all 11 American Spirit reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

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$5865*

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Ports

  • Amelia Island, Florida
  • JEKYLL ISLAND, GEORGIA
  • ST. SIMONS ISLAND, GEORGIA
  • Savannah, Georgia
  • HILTON HEAD ISLAND, SOUTH CAROLINA
  • BEAUFORT, SOUTH CAROLINA
  • RIVER CRUISING
  • Charleston, South Carolina
  • Wilmington, North Carolina
  • BEAUFORT, NORTH CAROLINA
  • KITTY HAWK, NORTH CAROLINA
  • Norfolk, Virginia
  • ST. MICHAELS, MARYLAND
  • Baltimore, Maryland
View more ports

Ports

Amelia Island, Florida - JEKYLL ISLAND, GEORGIA - ST. SIMONS ISLAND, GEORGIA - Savannah, Georgia - HILTON HEAD ISLAND, SOUTH CAROLINA - BEAUFORT, SOUTH CAROLINA - RIVER CRUISING - Charleston, South Carolina - Wilmington, North Carolina - BEAUFORT, NORTH CAROLINA - KITTY HAWK, NORTH CAROLINA - Norfolk, Virginia - ST. MICHAELS, MARYLAND - Baltimore, Maryland - View more ports

American Eagle S

5.0
(2 Reviews)

2025 sail dates:

2026 sail dates:

$10585*
$756/night*
Oceanview
View Deal
$10585* dreamvacations.com $10585* luxuryonly.com
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Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

$10585*

$12360*

$16325*

See Offers

N/A

$10585*

$12360*

$16325*

Ports

  • Amelia Island, Florida
  • JEKYLL ISLAND, GEORGIA
  • ST. SIMONS ISLAND, GEORGIA
  • Savannah, Georgia
  • HILTON HEAD ISLAND, SOUTH CAROLINA
  • BEAUFORT, SOUTH CAROLINA
  • RIVER CRUISING
  • Charleston, South Carolina
  • Wilmington, North Carolina
  • BEAUFORT, NORTH CAROLINA
  • KITTY HAWK, NORTH CAROLINA
  • Norfolk, Virginia
  • ST. MICHAELS, MARYLAND
  • Baltimore, Maryland
View more ports

Ports

Amelia Island, Florida - JEKYLL ISLAND, GEORGIA - ST. SIMONS ISLAND, GEORGIA - Savannah, Georgia - HILTON HEAD ISLAND, SOUTH CAROLINA - BEAUFORT, SOUTH CAROLINA - RIVER CRUISING - Charleston, South Carolina - Wilmington, North Carolina - BEAUFORT, NORTH CAROLINA - KITTY HAWK, NORTH CAROLINA - Norfolk, Virginia - ST. MICHAELS, MARYLAND - Baltimore, Maryland - View more ports

American Liberty XL

5.0
(1 Reviews)

2025 sail dates:

2026 sail dates: May 23

$11360*
$811/night*
Balcony
View Deal
$11360* dreamvacations.com $11360* luxuryonly.com
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Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$11360*

$15325*

See Offers

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$11360*

$15325*

 

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$12360*

$16325*

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$12360*

$16325*

Ports

  • Juneau, Alaska
  • Haines, Alaska
  • Cruise Glacier Bay
  • PETERSBURG, ALASKA
  • Wrangell, Alaska
  • Cruise Tracy Arm Fjord, Alaska
View more ports

Ports

Juneau, Alaska - Haines, Alaska - Cruise Glacier Bay - PETERSBURG, ALASKA - Wrangell, Alaska - Cruise Tracy Arm Fjord, Alaska - View more ports

American Constitution XL

5.0
(4 Reviews)

2025 sail dates: May 24, May 31, Jul 07, Jul 14, Jul 21, Aug 04, Aug 11 More

$6125*
$875/night*
Oceanview
View Deal
$6125* dreamvacations.com $6125* luxuryonly.com
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Read all 4 American Constitution reviews
91 - 100 of 125

All prices are per person based on double occupancy and do not include port/government fees and gratuities.

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