Colon, Panama cruises 224 Colon, Panama cruises

Your search Clear selections

Any Destination
All Sail Months
Any Length
Colon, Panama
Any Cruise Line
Any Ship

Close

224 cruises found

Sort by

Filter by

More

Ports

  • Miami, Florida
  • Cartagena, Colombia
  • Colon, Panama
  • Panama Canal Transit
  • Puerto Caldera, Costa Rica
  • Puerto Quetzal, Guatemala
  • Acapulco, Mexico
  • Cabo San Lucas, Mexico
  • San Pedro (Los Angeles), California
View more ports

Ports

Miami, Florida - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Puerto Caldera, Costa Rica - Puerto Quetzal, Guatemala - Acapulco, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - View more ports

Ports

  • Tampa, Florida
  • George Town, Grand Cayman
  • Cartagena, Colombia
  • Colon, Panama
  • Puerto Limon, Costa Rica
  • Cozumel, Mexico
View more ports

Ports

Tampa, Florida - George Town, Grand Cayman - Cartagena, Colombia - Colon, Panama - Puerto Limon, Costa Rica - Cozumel, Mexico - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Ports

  • Tampa, Florida
  • George Town, Grand Cayman
  • Puerto Limon, Costa Rica
  • Colon, Panama
  • Oranjestad, Aruba
  • Willemstad, Curacao
  • Amber Cove (Puerto Plata), Dominican Republic
View more ports

Ports

Tampa, Florida - George Town, Grand Cayman - Puerto Limon, Costa Rica - Colon, Panama - Oranjestad, Aruba - Willemstad, Curacao - Amber Cove (Puerto Plata), Dominican Republic - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Ports

  • Miami, Florida
  • George Town, Grand Cayman
  • Cartagena, Colombia
  • Colon, Panama
  • Panama Canal (Cruise Into Canal)
  • Puerto Limon, Costa Rica
  • Harvest Caye, Belize
  • Cozumel, Mexico
View more ports

Ports

Miami, Florida - George Town, Grand Cayman - Cartagena, Colombia - Colon, Panama - Panama Canal (Cruise Into Canal) - Puerto Limon, Costa Rica - Harvest Caye, Belize - Cozumel, Mexico - View more ports

Ports

  • Galveston, Texas
  • Cozumel, Mexico
  • Puerto Limon, Costa Rica
  • Colon, Panama
  • George Town, Grand Cayman
View more ports

Ports

Galveston, Texas - Cozumel, Mexico - Puerto Limon, Costa Rica - Colon, Panama - George Town, Grand Cayman - View more ports

Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

$1319*

N/A

$1839*

N/A

Ports

  • Miami, Florida
  • Cartagena, Colombia
  • Colon, Panama
  • Panama Canal Transit
  • Puntarenas, Costa Rica
  • Puerto Quetzal, Guatemala
  • Acapulco, Mexico
  • Cabo San Lucas, Mexico
  • San Pedro (Los Angeles), California
View more ports

Ports

Miami, Florida - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Acapulco, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - View more ports

Ports

  • Colon, Panama
  • Cartagena, Colombia
  • Oranjestad, Aruba
  • Kralendijk, Bonaire
View more ports

Ports

Colon, Panama - Cartagena, Colombia - Oranjestad, Aruba - Kralendijk, Bonaire - View more ports

Ports

  • Miami, Florida
  • Puerto Limon, Costa Rica
  • Colon, Panama
  • Cartagena, Colombia
  • Oranjestad, Aruba
  • Willemstad, Curacao
View more ports

Ports

Miami, Florida - Puerto Limon, Costa Rica - Colon, Panama - Cartagena, Colombia - Oranjestad, Aruba - Willemstad, Curacao - View more ports

Ports

  • Cartagena, Colombia
  • Kralendijk, Bonaire
  • Oranjestad, Aruba
  • Colon, Panama
View more ports

Ports

Cartagena, Colombia - Kralendijk, Bonaire - Oranjestad, Aruba - Colon, Panama - View more ports

Ports

  • Miami, Florida
  • Cartagena, Colombia
  • Colon, Panama
  • Panama Canal Transit
  • Puntarenas, Costa Rica
  • Puerto Quetzal, Guatemala
  • Acapulco, Mexico
  • Cabo San Lucas, Mexico
  • San Pedro (Los Angeles), California
View more ports

Ports

Miami, Florida - Cartagena, Colombia - Colon, Panama - Panama Canal Transit - Puntarenas, Costa Rica - Puerto Quetzal, Guatemala - Acapulco, Mexico - Cabo San Lucas, Mexico - San Pedro (Los Angeles), California - View more ports

All prices are per person based on double occupancy and do not include port/government fees and gratuities.