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Cruises on American Cruise Line 160 cruises on American Cruise Line found

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Ports

  • Nashville, Tennessee
  • RIVER CRUISING
  • Paducah, Kentucky
  • Savannah, Tennessee
  • Florence, Alabama
  • Decatur, Alabama
  • Chattanooga, Tennessee
View more ports

Ports

Nashville, Tennessee - RIVER CRUISING - Paducah, Kentucky - Savannah, Tennessee - Florence, Alabama - Decatur, Alabama - Chattanooga, Tennessee - View more ports

American Symphony S

4.2
(4 Reviews)

2026 sail dates: Apr 29, May 13, May 27, Jun 10, Sep 16, Sep 30, Oct 14 More

$4915*
$702/night*
Balcony
View Deal
$4915* luxuryonly.com $4915* dreamvacations.com
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Partners Bonus Offers Inside Oceanview Balcony Suite
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$5275*

$7295*

 

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$7295*

 

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$5275*

$7295*

 

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$4915*

$6800*

 

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$4915*

$6800*

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$5275*

$7295*

 

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Ports

  • Portland, Oregon
  • Astoria, Oregon
  • KALAMA, WASHINGTON
  • THE DALLES, OREGON
  • Cruise Columbia River
  • Pendleton, Oregon
  • Clarkston, Washington
View more ports

Ports

Portland, Oregon - Astoria, Oregon - KALAMA, WASHINGTON - THE DALLES, OREGON - Cruise Columbia River - Pendleton, Oregon - Clarkston, Washington - View more ports

American West S

5.0
(1 Reviews)

2026 sail dates: May 18, Jun 01, Jun 15, Jun 29, Jul 13, Jul 27, Aug 10, Aug 24, Sep 07, Sep 21, Oct 05 More

$4925*
$704/night*
Oceanview
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$4925* luxuryonly.com $4925* dreamvacations.com
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Ports

  • Seattle, Washington
  • ANACORTES, WASHINGTON
  • FRIDAY HARBOR, SAN JUAN ISLAND, WASHINGTON
  • Cruise Inside Passage, Alaska
  • Ketchikan, Alaska
  • Wrangell, Alaska
  • PETERSBURG, ALASKA
  • Cruise Tracy Arm Fjord, Alaska
  • Cruise Glacier Bay
  • Haines, Alaska
  • Skagway, Alaska
  • Juneau, Alaska
View more ports

Ports

Seattle, Washington - ANACORTES, WASHINGTON - FRIDAY HARBOR, SAN JUAN ISLAND, WASHINGTON - Cruise Inside Passage, Alaska - Ketchikan, Alaska - Wrangell, Alaska - PETERSBURG, ALASKA - Cruise Tracy Arm Fjord, Alaska - Cruise Glacier Bay - Haines, Alaska - Skagway, Alaska - Juneau, Alaska - View more ports

American Constitution XL

5.0
(4 Reviews)

2026 sail dates:

$10810*
$772/night*
Oceanview
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$10810* luxuryonly.com $10810* dreamvacations.com
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N/A

$10810*

$12435*

$16380*

 

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$10810*

$12435*

$16380*

Ports

  • Clarkston, Washington
  • Pendleton, Oregon
  • Cruise Columbia River
  • THE DALLES, OREGON
  • KALAMA, WASHINGTON
  • Astoria, Oregon
  • RIVER CRUISING
  • Portland, Oregon
View more ports

Ports

Clarkston, Washington - Pendleton, Oregon - Cruise Columbia River - THE DALLES, OREGON - KALAMA, WASHINGTON - Astoria, Oregon - RIVER CRUISING - Portland, Oregon - View more ports

American West S

5.0
(1 Reviews)

2026 sail dates: May 11, Jun 08, Jun 22, Jul 06, Jul 20, Aug 03, Aug 17, Aug 31, Sep 14, Sep 28, Oct 12 More

$4925*
$704/night*
Oceanview
View Deal
$4925* luxuryonly.com $4925* dreamvacations.com
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Ports

  • New York, New York
  • OLD SAYBROOK, CONNECTICUT
  • New London, Connecticut
  • Newport, Rhode Island
  • Plymouth, Massachusetts
  • Boston, Massachusetts
View more ports

Ports

New York, New York - OLD SAYBROOK, CONNECTICUT - New London, Connecticut - Newport, Rhode Island - Plymouth, Massachusetts - Boston, Massachusetts - View more ports

American Glory S

5.0
(1 Reviews)

2026 sail dates:

$6350*
$907/night*
Oceanview
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$6350* luxuryonly.com $6350* dreamvacations.com
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Partners Bonus Offers Inside Oceanview Balcony Suite
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$6350*

$7415*

$9875*

 

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$6350*

$7415*

$9875*

Ports

  • Boston, Massachusetts
  • Portland, Maine
  • BATH, MAINE
  • Boothbay, Maine
  • Bar Harbor, Maine
  • BANGOR, MAINE
  • Rockland, Maine
  • PORTSMOUTH, NEW HAMPSHIRE
  • Gloucester, Massachusetts
  • Provincetown, Massachusetts
  • Newport, Rhode Island
  • Martha's Vineyard, Massachusetts
  • Plymouth, Massachusetts
View more ports

Ports

Boston, Massachusetts - Portland, Maine - BATH, MAINE - Boothbay, Maine - Bar Harbor, Maine - BANGOR, MAINE - Rockland, Maine - PORTSMOUTH, NEW HAMPSHIRE - Gloucester, Massachusetts - Provincetown, Massachusetts - Newport, Rhode Island - Martha's Vineyard, Massachusetts - Plymouth, Massachusetts - View more ports

American Pioneer S

2026 sail dates: May 17, May 31, Jun 14, Aug 09, Aug 23, Sep 06, Sep 20 More

$13940*
$996/night*
Balcony
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$13940* luxuryonly.com $13940* dreamvacations.com
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Partners Bonus Offers Inside Oceanview Balcony Suite
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$13940*

$16380*

 

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$13940*

$16380*

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$13940*

$16380*

 

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$13940*

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$13940*

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$14730*

$17310*

 

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$14730*

$17310*

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$14730*

$17310*

 

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$15515*

$18235*

 

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$15515*

$18235*

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$15515*

$18235*

 

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Ports

  • New York, New York
  • OLD SAYBROOK, CONNECTICUT
  • New London, Connecticut
  • Newport, Rhode Island
  • Plymouth, Massachusetts
  • Boston, Massachusetts
View more ports

Ports

New York, New York - OLD SAYBROOK, CONNECTICUT - New London, Connecticut - Newport, Rhode Island - Plymouth, Massachusetts - Boston, Massachusetts - View more ports

American Patriot S

2026 sail dates: May 31

$7415*
$1059/night*
Balcony
View Deal
$7415* luxuryonly.com $7415* dreamvacations.com
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Partners Bonus Offers Inside Oceanview Balcony Suite
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$7415*

$9875*

 

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$7415*

$9875*

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$7415*

$9875*

 

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$7415*

$9875*

Ports

  • Juneau, Alaska
  • Haines, Alaska
  • Cruise Glacier Bay
  • PETERSBURG, ALASKA
  • Wrangell, Alaska
  • Cruise Tracy Arm Fjord, Alaska
View more ports

Ports

Juneau, Alaska - Haines, Alaska - Cruise Glacier Bay - PETERSBURG, ALASKA - Wrangell, Alaska - Cruise Tracy Arm Fjord, Alaska - View more ports

American Constitution XL

5.0
(4 Reviews)

2026 sail dates: May 30, Jul 06, Jul 13, Jul 20, Jul 27, Aug 03, Aug 10 More

$6725*
$961/night*
Oceanview
View Deal
$6725* luxuryonly.com $6725* dreamvacations.com
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Ports

  • New Orleans, Louisiana
  • Houmas House Plantation, Louisiana
  • Baton Rouge, Louisiana
  • St. Francisville, Louisiana
  • Natchez, Mississippi
  • Vicksburg, Mississippi
  • Memphis, Tennessee
View more ports

Ports

New Orleans, Louisiana - Houmas House Plantation, Louisiana - Baton Rouge, Louisiana - St. Francisville, Louisiana - Natchez, Mississippi - Vicksburg, Mississippi - Memphis, Tennessee - View more ports

American Heritage S

4.8
(7 Reviews)

2026 sail dates: Sep 26,

$4610*
$659/night*
Oceanview
View Deal
$4610* luxuryonly.com $4610* dreamvacations.com
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Partners Bonus Offers Inside Oceanview Balcony Suite
See Offers

N/A

$4610*

$5275*

$7295*

 

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$4610*

$5275*

$7295*

See Offers

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$4925*

$5635*

$7795*

 

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$4925*

$5635*

$7795*

Ports

  • Boston, Massachusetts
  • Portland, Maine
  • Rockland, Maine
  • Bar Harbor, Maine
  • Boothbay, Maine
  • BATH, MAINE
  • Gloucester, Massachusetts
  • RIVER CRUISING
  • Newport, Rhode Island
  • Martha's Vineyard, Massachusetts
View more ports

Ports

Boston, Massachusetts - Portland, Maine - Rockland, Maine - Bar Harbor, Maine - Boothbay, Maine - BATH, MAINE - Gloucester, Massachusetts - RIVER CRUISING - Newport, Rhode Island - Martha's Vineyard, Massachusetts - View more ports

American Patriot S

2026 sail dates: Jun 07, Jun 17, Jun 27, Jul 17, Jul 27, Aug 06, Aug 16, Aug 26 More

$10745*
$1075/night*
Balcony
View Deal
$10745* luxuryonly.com $10745* dreamvacations.com
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Partners Bonus Offers Inside Oceanview Balcony Suite
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$10745*

$14310*

 

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$10745*

$14310*

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$10745*

$14310*

 

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$14310*

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$10745*

$14310*

 

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$14310*

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$10745*

$14310*

 

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$11320*

$15075*

 

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$15075*

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$11320*

$15075*

 

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41 - 50 of 160

All prices are per person based on double occupancy and do not include port/government fees and gratuities.

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