1. Home
  2. Find a cruise
  3. American Cruise Line cruises

American Cruise Line Cruises to River Cruises - United States 125 cruises on American Cruise Line found

Your search Clear selections

Any Destination
All Sail Months
Any Length
Any Port
American Cruise Line
Any Ship

Close

125 cruises found

Filters Save search

Sort by

Filter by

More
Save search

Ports

  • Charleston, South Carolina
  • BEAUFORT, SOUTH CAROLINA
  • HILTON HEAD ISLAND, SOUTH CAROLINA
  • Savannah, Georgia
  • JEKYLL ISLAND, GEORGIA
  • Amelia Island, Florida
  • Jacksonville, Florida
View more ports

Ports

Charleston, South Carolina - BEAUFORT, SOUTH CAROLINA - HILTON HEAD ISLAND, SOUTH CAROLINA - Savannah, Georgia - JEKYLL ISLAND, GEORGIA - Amelia Island, Florida - Jacksonville, Florida - View more ports

American Glory S

5.0
(1 Reviews)

2026 sail dates: Apr 11, Nov 25, Dec 09, Dec 23 More

$5630*
$804/night*
Oceanview
View Deal
$5630* dreamvacations.com $5630* luxuryonly.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

$5630*

$6575*

$8755*

 

N/A

$5630*

$6575*

$8755*

 

N/A

$5990*

$6995*

$9315*

 

N/A

$5990*

$6995*

$9315*

 

N/A

$5630*

$6575*

$8755*

 

N/A

$5630*

$6575*

$8755*

 

N/A

$5630*

$6575*

$8755*

 

N/A

$5630*

$6575*

$8755*

 

N/A

$5630*

$6575*

$8755*

 

N/A

$5630*

$6575*

$8755*

Ports

  • New Orleans, Louisiana
  • Houmas House Plantation, Louisiana
  • Baton Rouge, Louisiana
  • St. Francisville, Louisiana
  • Natchez, Mississippi
  • Vicksburg, Mississippi
  • RIVER CRUISING
  • Memphis, Tennessee
View more ports

Ports

New Orleans, Louisiana - Houmas House Plantation, Louisiana - Baton Rouge, Louisiana - St. Francisville, Louisiana - Natchez, Mississippi - Vicksburg, Mississippi - RIVER CRUISING - Memphis, Tennessee - View more ports

American Serenade S

2026 sail dates:

$5995*
$856/night*
Balcony
View Deal
$5995* dreamvacations.com $5995* luxuryonly.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$5995*

$8290*

 

N/A

N/A

$5995*

$8290*

Ports

  • HAYDEN ISLAND, PORTLAND, OREGON
  • Portland, Oregon
  • Astoria, Oregon
  • Mount St. Helens, Washington
  • Cruise Columbia River
  • THE DALLES, OREGON
  • Pendleton, Oregon
  • CRUISE SNAKE RIVER, PACIFIC NORTHWEST, USA
  • Clarkston, Washington
View more ports

Ports

HAYDEN ISLAND, PORTLAND, OREGON - Portland, Oregon - Astoria, Oregon - Mount St. Helens, Washington - Cruise Columbia River - THE DALLES, OREGON - Pendleton, Oregon - CRUISE SNAKE RIVER, PACIFIC NORTHWEST, USA - Clarkston, Washington - View more ports

American Jazz S

4.7
(8 Reviews)

2026 sail dates: May 02, May 16, May 30, Jun 13, Jun 27, Jul 11, Jul 25, Aug 08, Aug 22, Sep 05, Sep 19, Oct 03, Oct 17, Oct 31, More

$5995*
$856/night*
Balcony
View Deal
$5995* dreamvacations.com $5995* luxuryonly.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 8 American Jazz reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$5995*

$8290*

 

N/A

N/A

$5995*

$8290*

 

N/A

N/A

$6355*

$8785*

 

N/A

N/A

$6355*

$8785*

 

N/A

N/A

$6355*

$8785*

 

N/A

N/A

$6355*

$8785*

 

N/A

N/A

$6355*

$8785*

 

N/A

N/A

$6355*

$8785*

 

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$7075*

$9780*

 

N/A

N/A

$7075*

$9780*

 

N/A

N/A

$7075*

$9780*

 

N/A

N/A

$7075*

$9780*

 

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$6715*

$9285*

 

N/A

N/A

$6715*

$9285*

Ports

  • Clarkston, Washington
  • Pendleton, Oregon
  • Cruise Columbia River
  • THE DALLES, OREGON
  • KALAMA, WASHINGTON
  • Astoria, Oregon
  • RIVER CRUISING
  • Portland, Oregon
View more ports

Ports

Clarkston, Washington - Pendleton, Oregon - Cruise Columbia River - THE DALLES, OREGON - KALAMA, WASHINGTON - Astoria, Oregon - RIVER CRUISING - Portland, Oregon - View more ports

American Pride S

4.4
(7 Reviews)

2026 sail dates: May 04, May 18, Jun 01, Jun 15, Jun 29, Jul 13, Jul 27, Aug 10, Aug 24, Sep 07, Sep 21, Oct 05, Oct 19, Nov 02, More

$4925*
$704/night*
Oceanview
View Deal
$4925* dreamvacations.com $4925* luxuryonly.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 7 American Pride reviews

Ports

  • Portland, Oregon
  • Astoria, Oregon
  • KALAMA, WASHINGTON
  • THE DALLES, OREGON
  • Cruise Columbia River
  • Pendleton, Oregon
  • Clarkston, Washington
View more ports

Ports

Portland, Oregon - Astoria, Oregon - KALAMA, WASHINGTON - THE DALLES, OREGON - Cruise Columbia River - Pendleton, Oregon - Clarkston, Washington - View more ports

American Pride S

4.4
(7 Reviews)

2026 sail dates: Apr 27, May 11, May 25, Jun 08, Jun 22, Jul 06, Jul 20, Aug 03, Aug 17, Aug 31, Sep 14, Sep 28, Oct 12, Oct 26, More

$4925*
$704/night*
Oceanview
View Deal
$4925* dreamvacations.com $4925* luxuryonly.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 7 American Pride reviews

Ports

  • Nashville, Tennessee
  • RIVER CRUISING
  • Paducah, Kentucky
  • Savannah, Tennessee
  • Florence, Alabama
  • Decatur, Alabama
  • Chattanooga, Tennessee
View more ports

Ports

Nashville, Tennessee - RIVER CRUISING - Paducah, Kentucky - Savannah, Tennessee - Florence, Alabama - Decatur, Alabama - Chattanooga, Tennessee - View more ports

American Symphony S

4.2
(4 Reviews)

2026 sail dates: Apr 29, May 13, May 27, Jun 10, Sep 16, Sep 30, Oct 14 More

$4915*
$702/night*
Balcony
View Deal
$4915* dreamvacations.com $4915* luxuryonly.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 4 American Symphony reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$4915*

$6800*

 

N/A

N/A

$4915*

$6800*

 

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$5275*

$7295*

 

N/A

N/A

$5275*

$7295*

Ports

  • Portland, Oregon
  • Astoria, Oregon
  • KALAMA, WASHINGTON
  • THE DALLES, OREGON
  • Cruise Columbia River
  • Pendleton, Oregon
  • Clarkston, Washington
View more ports

Ports

Portland, Oregon - Astoria, Oregon - KALAMA, WASHINGTON - THE DALLES, OREGON - Cruise Columbia River - Pendleton, Oregon - Clarkston, Washington - View more ports

American West S

5.0
(1 Reviews)

2026 sail dates: May 04, Jun 01, Jun 15, Jun 29, Jul 13, Jul 27, Aug 10, Aug 24, Sep 07, Sep 21, Oct 05 More

$4925*
$704/night*
Oceanview
View Deal
$4925* dreamvacations.com $4925* luxuryonly.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Ports

  • Portland, Maine
  • BATH, MAINE
  • Bar Harbor, Maine
  • PORTSMOUTH, NEW HAMPSHIRE
  • Gloucester, Massachusetts
  • Boston, Massachusetts
  • Martha's Vineyard, Massachusetts
  • Newport, Rhode Island
  • RIVER CRUISING
  • OLD SAYBROOK, CONNECTICUT
  • New London, Connecticut
  • New York, New York
View more ports

Ports

Portland, Maine - BATH, MAINE - Bar Harbor, Maine - PORTSMOUTH, NEW HAMPSHIRE - Gloucester, Massachusetts - Boston, Massachusetts - Martha's Vineyard, Massachusetts - Newport, Rhode Island - RIVER CRUISING - OLD SAYBROOK, CONNECTICUT - New London, Connecticut - New York, New York - View more ports

American Independence S

4.6
(8 Reviews)

2025 sail dates:

$11030*
$788/night*
Oceanview
View Deal
$11030* dreamvacations.com $11030* luxuryonly.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 8 American Independence reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

$11030*

$13140*

$17310*

 

N/A

$11030*

$13140*

$17310*

Ports

  • New York, New York
  • SLEEPY HOLLOW, NEW YORK
  • WEST POINT, NEW YORK
  • KINGSTON, NY
  • CATSKILL, NEW YORK
  • RIVER CRUISING
  • Albany, New York
View more ports

Ports

New York, New York - SLEEPY HOLLOW, NEW YORK - WEST POINT, NEW YORK - KINGSTON, NY - CATSKILL, NEW YORK - RIVER CRUISING - Albany, New York - View more ports

American Eagle S

5.0
(2 Reviews)

2025 sail dates: Oct 08, Oct 22

$7070*
$1010/night*
Oceanview
View Deal
$7070* dreamvacations.com $7070* luxuryonly.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

$7070*

$8255*

$10990*

 

N/A

$7070*

$8255*

$10990*

 

N/A

$7430*

$8575*

$11550*

 

N/A

$7430*

$8575*

$11550*

 

N/A

$7430*

$8575*

$11550*

 

N/A

$7430*

$8575*

$11550*

Ports

  • New York, New York
  • CATSKILL, NEW YORK
  • Albany, New York
  • KINGSTON, NY
  • WEST POINT, NEW YORK
  • SLEEPY HOLLOW, NEW YORK
View more ports

Ports

New York, New York - CATSKILL, NEW YORK - Albany, New York - KINGSTON, NY - WEST POINT, NEW YORK - SLEEPY HOLLOW, NEW YORK - View more ports

American Star S

4.5
(9 Reviews)

2025 sail dates:

$5555*
$794/night*
Oceanview
View Deal
$5555* dreamvacations.com $5555* luxuryonly.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Read all 9 American Star reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

$5555*

$6615*

$8785*

 

N/A

$5555*

$6615*

$8785*

21 - 30 of 125

All prices are per person based on double occupancy and do not include port/government fees and gratuities.

More popular destinations for American Cruise Line

More popular cruise lines that sail to River Cruises - United States

More popular departure ports with sailings to River Cruises - United States