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Ports

  • New Orleans, Louisiana
  • DARROW, LOUISIANA
  • St. Francisville, Louisiana
  • Natchez, Mississippi
  • Vicksburg, Mississippi
  • RIVER CRUISING
  • Memphis, Tennessee
View more ports

Ports

New Orleans, Louisiana - DARROW, LOUISIANA - St. Francisville, Louisiana - Natchez, Mississippi - Vicksburg, Mississippi - RIVER CRUISING - Memphis, Tennessee - View more ports

Viking Mississippi S

4.0
(11 Reviews)

2025 sail dates: Mar 08, Mar 22, Apr 05, Apr 19, May 03, May 17, May 31, Oct 25, Nov 08, Dec 06, More

2026 sail dates: Feb 21, Mar 07, Mar 21, Apr 04, Apr 18, May 02, May 16, May 30, Sep 19, Oct 03, Dec 01 More

$3999*
$571/night*
Balcony
View Deal
$3999* luxurycruiseconnections.com $3999* luxuryonly.com $3999* dreamvacations.com $3999* directlinecruises.com
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Partners Bonus Offers Inside Oceanview Balcony Suite
 

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Ports

  • Memphis, Tennessee
  • RIVER CRUISING
  • Paducah, Kentucky
  • Dover, Tennessee
  • CLARKSVILLE, TENNESSEE
  • Nashville, Tennessee
View more ports

Ports

Memphis, Tennessee - RIVER CRUISING - Paducah, Kentucky - Dover, Tennessee - CLARKSVILLE, TENNESSEE - Nashville, Tennessee - View more ports

American Splendor S

4.1
(4 Reviews)

2025 sail dates: Jun 11, Jun 25, Jul 23, Sep 03, Sep 17, Oct 01, Oct 15 More

2026 sail dates: Jun 10, Jun 24, Sep 02, Sep 30, Oct 14 More

$4295*
$614/night*
Oceanview
View Deal
$4295* dreamvacations.com $4295* luxuryonly.com
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Read all 4 American Splendor reviews

Ports

  • New Orleans, Louisiana
  • OAK ALLEY PLANTATION, VACHERIE, LOUISIANA
  • Houmas House Plantation, Louisiana
  • Baton Rouge, Louisiana
  • St. Francisville, Louisiana
  • Natchez, Mississippi
  • Vicksburg, Mississippi
  • Greenville, Mississippi
  • Memphis, Tennessee
  • New Madrid, Missouri
  • Cape Girardeau, Missouri
  • CHESTER, ILLINOIS
  • St. Louis, Missouri
  • RIVER CRUISING
  • Hannibal, Missouri
  • FORT MADISON, IOWA
  • DAVENPORT, IOWA
  • Dubuque, Iowa
  • Winona, Minnesota
  • Red Wing, Minnesota
  • St. Paul, Minnesota
View more ports

Ports

New Orleans, Louisiana - OAK ALLEY PLANTATION, VACHERIE, LOUISIANA - Houmas House Plantation, Louisiana - Baton Rouge, Louisiana - St. Francisville, Louisiana - Natchez, Mississippi - Vicksburg, Mississippi - Greenville, Mississippi - Memphis, Tennessee - New Madrid, Missouri - Cape Girardeau, Missouri - CHESTER, ILLINOIS - St. Louis, Missouri - RIVER CRUISING - Hannibal, Missouri - FORT MADISON, IOWA - DAVENPORT, IOWA - Dubuque, Iowa - Winona, Minnesota - Red Wing, Minnesota - St. Paul, Minnesota - View more ports

American Serenade S

2025 sail dates:

2026 sail dates: Jun 13

$15890*
$757/night*
Balcony
View Deal
$15890* dreamvacations.com $15890* luxuryonly.com
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Partners Bonus Offers Inside Oceanview Balcony Suite
 

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$15890*

$21790*

 

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$21790*

 

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Ports

  • Nashville, Tennessee
  • CLARKSVILLE, TENNESSEE
  • Dover, Tennessee
  • RIVER CRUISING
  • Paducah, Kentucky
  • Memphis, Tennessee
View more ports

Ports

Nashville, Tennessee - CLARKSVILLE, TENNESSEE - Dover, Tennessee - RIVER CRUISING - Paducah, Kentucky - Memphis, Tennessee - View more ports

American Splendor S

4.1
(4 Reviews)

2025 sail dates: Jun 18, Sep 10, Sep 24, Oct 08, Oct 22 More

$4295*
$614/night*
Oceanview
View Deal
$4295* dreamvacations.com $4295* luxuryonly.com
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Top positive review

Top critical review

Read all 4 American Splendor reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

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$4610*

$5275*

$7295*

 

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$4610*

$5275*

$7295*

 

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$4295*

$4915*

$6800*

 

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$6800*

 

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$4925*

$5635*

$7795*

 

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$5635*

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Ports

  • St. Louis, Missouri
  • Cape Girardeau, Missouri
  • RIVER CRUISING
  • Paducah, Kentucky
  • EVANSVILLE, INDIANA
  • Henderson, Kentucky
  • Louisville, Kentucky
  • Cincinnati, Ohio
  • MAYSVILLE, KENTUCKY
  • MARIETTA, OHIO
  • Pittsburgh, Pennsylvania
View more ports

Ports

St. Louis, Missouri - Cape Girardeau, Missouri - RIVER CRUISING - Paducah, Kentucky - EVANSVILLE, INDIANA - Henderson, Kentucky - Louisville, Kentucky - Cincinnati, Ohio - MAYSVILLE, KENTUCKY - MARIETTA, OHIO - Pittsburgh, Pennsylvania - View more ports

American Melody S

5.0
(8 Reviews)

2025 sail dates:

2026 sail dates: Aug 01

$9015*
$644/night*
Balcony
View Deal
$9015* dreamvacations.com $9015* luxuryonly.com
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Top positive review

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Read all 8 American Melody reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

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$9015*

$12365*

 

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$9015*

$12365*

 

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$9015*

$12365*

 

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$9015*

$12365*

Ports

  • Nashville, Tennessee
  • CLARKSVILLE, TENNESSEE
  • Dover, Tennessee
  • RIVER CRUISING
  • Paducah, Kentucky
  • Memphis, Tennessee
View more ports

Ports

Nashville, Tennessee - CLARKSVILLE, TENNESSEE - Dover, Tennessee - RIVER CRUISING - Paducah, Kentucky - Memphis, Tennessee - View more ports

American Symphony S

4.2
(4 Reviews)

2025 sail dates: Jun 25, Aug 20, Oct 29 More

$4915*
$702/night*
Balcony
View Deal
$4915* dreamvacations.com $4915* luxuryonly.com
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Read all 4 American Symphony reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

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N/A

$5275*

$7295*

 

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$5275*

$7295*

 

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$4915*

$6800*

 

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$6800*

 

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$6800*

 

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$6800*

 

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$5275*

$7295*

 

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$5275*

$7295*

Ports

  • Pittsburgh, Pennsylvania
  • RIVER CRUISING
  • MARIETTA, OHIO
  • MAYSVILLE, KENTUCKY
  • Cincinnati, Ohio
  • Louisville, Kentucky
  • Henderson, Kentucky
  • EVANSVILLE, INDIANA
  • Paducah, Kentucky
  • Cape Girardeau, Missouri
  • St. Louis, Missouri
View more ports

Ports

Pittsburgh, Pennsylvania - RIVER CRUISING - MARIETTA, OHIO - MAYSVILLE, KENTUCKY - Cincinnati, Ohio - Louisville, Kentucky - Henderson, Kentucky - EVANSVILLE, INDIANA - Paducah, Kentucky - Cape Girardeau, Missouri - St. Louis, Missouri - View more ports

American Melody S

5.0
(8 Reviews)

2025 sail dates:

2026 sail dates:

$9015*
$644/night*
Balcony
View Deal
$9015* dreamvacations.com $9015* luxuryonly.com
Loading itinerary...
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Top positive review

Top critical review

Read all 8 American Melody reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$9015*

$12365*

 

N/A

N/A

$9015*

$12365*

Ports

  • St. Louis, Missouri
  • Hannibal, Missouri
  • RIVER CRUISING
  • MUSCATINE, IOWA
  • Dubuque, Iowa
  • Winona, Minnesota
  • Red Wing, Minnesota
  • St. Paul, Minnesota
View more ports

Ports

St. Louis, Missouri - Hannibal, Missouri - RIVER CRUISING - MUSCATINE, IOWA - Dubuque, Iowa - Winona, Minnesota - Red Wing, Minnesota - St. Paul, Minnesota - View more ports

American Serenade S

2025 sail dates:

2026 sail dates: Aug 22

$5635*
$805/night*
Balcony
View Deal
$5635* dreamvacations.com $5635* luxuryonly.com
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Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$5635*

$7795*

 

N/A

N/A

$5635*

$7795*

 

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$5635*

$7795*

 

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$5635*

$7795*

Ports

  • St. Paul, Minnesota
  • Winona, Minnesota
  • Dubuque, Iowa
  • DAVENPORT, IOWA
  • FORT MADISON, IOWA
  • Hannibal, Missouri
  • St. Louis, Missouri
  • RIVER CRUISING
  • Memphis, Tennessee
  • Vicksburg, Mississippi
  • Natchez, Mississippi
  • Baton Rouge, Louisiana
  • New Orleans, Louisiana
View more ports

Ports

St. Paul, Minnesota - Winona, Minnesota - Dubuque, Iowa - DAVENPORT, IOWA - FORT MADISON, IOWA - Hannibal, Missouri - St. Louis, Missouri - RIVER CRUISING - Memphis, Tennessee - Vicksburg, Mississippi - Natchez, Mississippi - Baton Rouge, Louisiana - New Orleans, Louisiana - View more ports

American Melody S

5.0
(8 Reviews)

2025 sail dates:

2026 sail dates:

$11945*
$853/night*
Balcony
View Deal
$11945* dreamvacations.com $11945* luxuryonly.com
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Top positive review

Top critical review

Read all 8 American Melody reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$11945*

$16380*

 

N/A

N/A

$11945*

$16380*

Ports

  • WASHINGTON, D.C. USA
  • ANNAPOLIS, MARYLAND
  • ST. MICHAELS, MARYLAND
  • CAMBRIDGE, MARYLAND
  • RIVER CRUISING
  • Norfolk, Virginia
  • Williamsburg, Virginia
  • Mt Vernon, Virginia
View more ports

Ports

WASHINGTON, D.C. USA - ANNAPOLIS, MARYLAND - ST. MICHAELS, MARYLAND - CAMBRIDGE, MARYLAND - RIVER CRUISING - Norfolk, Virginia - Williamsburg, Virginia - Mt Vernon, Virginia - View more ports

American Patriot S

2025 sail dates:

2026 sail dates: Oct 19, Oct 29,

$9020*
$902/night*
Balcony
View Deal
$9020* dreamvacations.com $9020* luxuryonly.com
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Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
 

N/A

N/A

$9595*

$12775*

 

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N/A

$9595*

$12775*

 

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$9595*

$12775*

 

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$9595*

$12775*

 

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$9020*

$12010*

 

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$9020*

$12010*

1 - 10 of 67

All prices are per person based on double occupancy and do not include port/government fees and gratuities.