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16 cruises found

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Ports

  • New Orleans, Louisiana
  • OAK ALLEY PLANTATION, VACHERIE, LOUISIANA
  • Houmas House Plantation, Louisiana
  • Baton Rouge, Louisiana
  • St. Francisville, Louisiana
  • Natchez, Mississippi
  • Vicksburg, Mississippi
  • Greenville, Mississippi
  • Memphis, Tennessee
  • New Madrid, Missouri
  • Cape Girardeau, Missouri
  • CHESTER, ILLINOIS
  • St. Louis, Missouri
  • RIVER CRUISING
  • Hannibal, Missouri
  • FORT MADISON, IOWA
  • DAVENPORT, IOWA
  • Dubuque, Iowa
  • Winona, Minnesota
  • Red Wing, Minnesota
  • St. Paul, Minnesota
View more ports

Ports

New Orleans, Louisiana - OAK ALLEY PLANTATION, VACHERIE, LOUISIANA - Houmas House Plantation, Louisiana - Baton Rouge, Louisiana - St. Francisville, Louisiana - Natchez, Mississippi - Vicksburg, Mississippi - Greenville, Mississippi - Memphis, Tennessee - New Madrid, Missouri - Cape Girardeau, Missouri - CHESTER, ILLINOIS - St. Louis, Missouri - RIVER CRUISING - Hannibal, Missouri - FORT MADISON, IOWA - DAVENPORT, IOWA - Dubuque, Iowa - Winona, Minnesota - Red Wing, Minnesota - St. Paul, Minnesota - View more ports

American Serenade S

2025 sail dates:

2026 sail dates: Jun 13

$15890*
$757/night*
Balcony
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$15890* luxuryonly.com $15890* dreamvacations.com
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$15890*

$21790*

 

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$15890*

$21790*

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$21790*

 

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$15890*

$21790*

Ports

  • New Orleans, Louisiana
  • Houmas House Plantation, Louisiana
  • Baton Rouge, Louisiana
  • St. Francisville, Louisiana
  • Natchez, Mississippi
  • Vicksburg, Mississippi
  • RIVER CRUISING
  • Memphis, Tennessee
View more ports

Ports

New Orleans, Louisiana - Houmas House Plantation, Louisiana - Baton Rouge, Louisiana - St. Francisville, Louisiana - Natchez, Mississippi - Vicksburg, Mississippi - RIVER CRUISING - Memphis, Tennessee - View more ports

American Serenade S

2026 sail dates:

$5995*
$856/night*
Balcony
View Deal
$5995* luxuryonly.com $5995* dreamvacations.com
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$5995*

$8290*

 

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$5995*

$8290*

Ports

  • Memphis, Tennessee
  • RIVER CRUISING
  • Vicksburg, Mississippi
  • Natchez, Mississippi
  • St. Francisville, Louisiana
  • Baton Rouge, Louisiana
  • Houmas House Plantation, Louisiana
  • New Orleans, Louisiana
View more ports

Ports

Memphis, Tennessee - RIVER CRUISING - Vicksburg, Mississippi - Natchez, Mississippi - St. Francisville, Louisiana - Baton Rouge, Louisiana - Houmas House Plantation, Louisiana - New Orleans, Louisiana - View more ports

American Symphony S

4.2
(4 Reviews)

2024 sail dates: Dec 07, Dec 30,

2025 sail dates: Jul 02, Jul 16, Nov 05, More

$4915*
$702/night*
Balcony
View Deal
$4915* luxuryonly.com $4915* dreamvacations.com
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$7295*

 

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Ports

  • New Orleans, Louisiana
  • Houmas House Plantation, Louisiana
  • Baton Rouge, Louisiana
  • St. Francisville, Louisiana
  • Natchez, Mississippi
  • Vicksburg, Mississippi
  • RIVER CRUISING
  • Memphis, Tennessee
View more ports

Ports

New Orleans, Louisiana - Houmas House Plantation, Louisiana - Baton Rouge, Louisiana - St. Francisville, Louisiana - Natchez, Mississippi - Vicksburg, Mississippi - RIVER CRUISING - Memphis, Tennessee - View more ports

American Melody S

5.0
(8 Reviews)

2024 sail dates:

2025 sail dates: Mar 29, Apr 12, Apr 26, May 10, More

$5275*
$754/night*
Balcony
View Deal
$5275* luxuryonly.com $5275* dreamvacations.com
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Read all 8 American Melody reviews
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$5635*

$7795*

 

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Ports

  • New Orleans, Louisiana
  • Houmas House Plantation, Louisiana
  • Baton Rouge, Louisiana
  • St. Francisville, Louisiana
  • Natchez, Mississippi
  • Vicksburg, Mississippi
  • RIVER CRUISING
  • Memphis, Tennessee
View more ports

Ports

New Orleans, Louisiana - Houmas House Plantation, Louisiana - Baton Rouge, Louisiana - St. Francisville, Louisiana - Natchez, Mississippi - Vicksburg, Mississippi - RIVER CRUISING - Memphis, Tennessee - View more ports

American Symphony S

4.2
(4 Reviews)

2024 sail dates: Nov 30, Dec 22

2025 sail dates: Sep 03,

$4915*
$702/night*
Balcony
View Deal
$4915* luxuryonly.com $4915* dreamvacations.com
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Read all 4 American Symphony reviews
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$5275*

$7295*

 

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$7295*

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Ports

  • Memphis, Tennessee
  • RIVER CRUISING
  • Vicksburg, Mississippi
  • Natchez, Mississippi
  • St. Francisville, Louisiana
  • Baton Rouge, Louisiana
  • Houmas House Plantation, Louisiana
  • New Orleans, Louisiana
View more ports

Ports

Memphis, Tennessee - RIVER CRUISING - Vicksburg, Mississippi - Natchez, Mississippi - St. Francisville, Louisiana - Baton Rouge, Louisiana - Houmas House Plantation, Louisiana - New Orleans, Louisiana - View more ports

American Melody S

5.0
(8 Reviews)

2024 sail dates:

2025 sail dates: Apr 05, Apr 19, May 03, May 17, More

$5275*
$754/night*
Balcony
View Deal
$5275* luxuryonly.com $5275* dreamvacations.com
Loading itinerary...
Loading reviews...

Top positive review

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Read all 8 American Melody reviews
Partners Bonus Offers Inside Oceanview Balcony Suite
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$5995*

$8290*

 

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Ports

  • Memphis, Tennessee
  • RIVER CRUISING
  • Vicksburg, Mississippi
  • Natchez, Mississippi
  • St. Francisville, Louisiana
  • Baton Rouge, Louisiana
  • Houmas House Plantation, Louisiana
  • New Orleans, Louisiana
View more ports

Ports

Memphis, Tennessee - RIVER CRUISING - Vicksburg, Mississippi - Natchez, Mississippi - St. Francisville, Louisiana - Baton Rouge, Louisiana - Houmas House Plantation, Louisiana - New Orleans, Louisiana - View more ports

American Serenade S

2025 sail dates: Mar 01, Mar 15, Mar 29, Apr 12, Apr 26, May 10, May 24, Jun 07, Sep 06, Sep 20, More

2026 sail dates: Feb 14, Mar 14, Mar 28, Apr 11, Apr 25, May 09, May 23, Jun 06, Sep 05, Sep 19, More

$5275*
$754/night*
Balcony
View Deal
$5275* luxuryonly.com $5275* dreamvacations.com
Loading itinerary...
Loading reviews...

Top positive review

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Partners Bonus Offers Inside Oceanview Balcony Suite
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$5635*

$7795*

 

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Ports

  • Memphis, Tennessee
  • RIVER CRUISING
  • Vicksburg, Mississippi
  • Natchez, Mississippi
  • St. Francisville, Louisiana
  • Baton Rouge, Louisiana
  • Houmas House Plantation, Louisiana
  • New Orleans, Louisiana
View more ports

Ports

Memphis, Tennessee - RIVER CRUISING - Vicksburg, Mississippi - Natchez, Mississippi - St. Francisville, Louisiana - Baton Rouge, Louisiana - Houmas House Plantation, Louisiana - New Orleans, Louisiana - View more ports

American Splendor S

4.1
(4 Reviews)

2025 sail dates: Mar 05, Mar 19, Apr 02, Apr 16, Apr 30, May 14, May 28, Jul 09, Oct 29, Nov 12, More

2026 sail dates: Mar 04, Mar 18, Apr 01, Apr 15, Apr 29, May 13, May 27, Jul 08, Nov 11, More

$4295*
$614/night*
Oceanview
View Deal
$4295* luxuryonly.com $4295* dreamvacations.com
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$4610*

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Ports

  • New Orleans, Louisiana
  • Houmas House Plantation, Louisiana
  • Baton Rouge, Louisiana
  • St. Francisville, Louisiana
  • Natchez, Mississippi
  • Vicksburg, Mississippi
  • RIVER CRUISING
  • Memphis, Tennessee
View more ports

Ports

New Orleans, Louisiana - Houmas House Plantation, Louisiana - Baton Rouge, Louisiana - St. Francisville, Louisiana - Natchez, Mississippi - Vicksburg, Mississippi - RIVER CRUISING - Memphis, Tennessee - View more ports

American Serenade S

2025 sail dates: Feb 22, Mar 08, Mar 22, Apr 05, Apr 19, May 03, May 17, May 31, Aug 30, Sep 13, More

2026 sail dates: Mar 07, Mar 21, Apr 18, May 02, May 16, May 30, Aug 29, Sep 12, More

$5275*
$754/night*
Balcony
View Deal
$5275* luxuryonly.com $5275* dreamvacations.com
Loading itinerary...
Loading reviews...

Top positive review

Top critical review

Partners Bonus Offers Inside Oceanview Balcony Suite
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$5275*

$7295*

 

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$5995*

$8290*

 

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$5995*

$8290*

 

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$5635*

$7795*

 

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$5635*

$7795*

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$7795*

 

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Ports

  • New Orleans, Louisiana
  • Houmas House Plantation, Louisiana
  • Baton Rouge, Louisiana
  • St. Francisville, Louisiana
  • Natchez, Mississippi
  • Vicksburg, Mississippi
  • RIVER CRUISING
  • Memphis, Tennessee
View more ports

Ports

New Orleans, Louisiana - Houmas House Plantation, Louisiana - Baton Rouge, Louisiana - St. Francisville, Louisiana - Natchez, Mississippi - Vicksburg, Mississippi - RIVER CRUISING - Memphis, Tennessee - View more ports

American Splendor S

4.1
(4 Reviews)

2025 sail dates: Mar 12, Mar 26, Apr 09, Apr 23, May 07, May 21, Jun 04, Jul 16, Nov 05 More

2026 sail dates: Feb 25, Mar 11, Mar 25, Apr 08, Apr 22, May 06, May 20, Jun 03 More

$4295*
$614/night*
Oceanview
View Deal
$4295* luxuryonly.com $4295* dreamvacations.com
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Top positive review

Top critical review

Read all 4 American Splendor reviews
1 - 10 of 16

All prices are per person based on double occupancy and do not include port/government fees and gratuities.