Cruises on American Cruise Line 160 cruises on American Cruise Line found
Your search Clear selections
160 cruises found
Sort by
Filter by
Ports
- Clarkston, Washington
- CRUISE SNAKE RIVER, PACIFIC NORTHWEST, USA
- Pendleton, Oregon
- THE DALLES, OREGON
- Cruise Columbia River
- Mount St. Helens, Washington
- Astoria, Oregon
- Portland, Oregon
Ports
Clarkston, Washington - CRUISE SNAKE RIVER, PACIFIC NORTHWEST, USA - Pendleton, Oregon - THE DALLES, OREGON - Cruise Columbia River - Mount St. Helens, Washington - Astoria, Oregon - Portland, Oregon - View more ports
Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
---|---|---|---|---|---|---|
|
See Offers |
N/A |
N/A |
$5995* |
$8290* |
|
|
N/A |
N/A |
$5995* |
$8290* |
||
|
See Offers |
N/A |
N/A |
$6355* |
$8785* |
|
|
N/A |
N/A |
$6355* |
$8785* |
||
|
See Offers |
N/A |
N/A |
$6355* |
$8785* |
|
|
N/A |
N/A |
$6355* |
$8785* |
||
|
See Offers |
N/A |
N/A |
$6715* |
$9285* |
|
|
N/A |
N/A |
$6715* |
$9285* |
||
|
See Offers |
N/A |
N/A |
$6715* |
$9285* |
|
|
N/A |
N/A |
$6715* |
$9285* |
||
|
See Offers |
N/A |
N/A |
$6715* |
$9285* |
|
|
N/A |
N/A |
$6715* |
$9285* |
||
|
See Offers |
N/A |
N/A |
$6715* |
$9285* |
|
|
N/A |
N/A |
$6715* |
$9285* |
||
|
See Offers |
N/A |
N/A |
$6715* |
$9285* |
|
|
N/A |
N/A |
$6715* |
$9285* |
||
|
See Offers |
N/A |
N/A |
$6715* |
$9285* |
|
|
N/A |
N/A |
$6715* |
$9285* |
||
|
See Offers |
N/A |
N/A |
$6715* |
$9285* |
|
|
N/A |
N/A |
$6715* |
$9285* |
||
|
See Offers |
N/A |
N/A |
$7075* |
$9780* |
|
|
N/A |
N/A |
$7075* |
$9780* |
||
|
See Offers |
N/A |
N/A |
$7075* |
$9780* |
|
|
N/A |
N/A |
$7075* |
$9780* |
||
|
See Offers |
N/A |
N/A |
$6715* |
$9285* |
|
|
N/A |
N/A |
$6715* |
$9285* |
||
|
See Offers |
N/A |
N/A |
$6715* |
$9285* |
|
|
N/A |
N/A |
$6715* |
$9285* |
||
|
See Offers |
N/A |
N/A |
$6355* |
$8785* |
|
|
N/A |
N/A |
$6355* |
$8785* |
Ports
- Boston, Massachusetts
- Gloucester, Massachusetts
- Plymouth, Massachusetts
- Martha's Vineyard, Massachusetts
- Newport, Rhode Island
- NEW BEDFORD, MASSACHUSETTS
- Provincetown, Massachusetts
Ports
Boston, Massachusetts - Gloucester, Massachusetts - Plymouth, Massachusetts - Martha's Vineyard, Massachusetts - Newport, Rhode Island - NEW BEDFORD, MASSACHUSETTS - Provincetown, Massachusetts - View more ports
Top positive review
Top critical review
Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
---|---|---|---|---|---|---|
|
See Offers |
N/A |
N/A |
$7835* |
$10435* |
|
|
N/A |
N/A |
$7835* |
$10435* |
Ports
- Boston, Massachusetts
- Plymouth, Massachusetts
- New London, Connecticut
- OLD SAYBROOK, CONNECTICUT
- New York, New York
Ports
Boston, Massachusetts - Plymouth, Massachusetts - New London, Connecticut - OLD SAYBROOK, CONNECTICUT - New York, New York - View more ports
Ports
- Nashville, Tennessee
- CLARKSVILLE, TENNESSEE
- Paducah, Kentucky
- Savannah, Tennessee
- Florence, Alabama
- Decatur, Alabama
- Chattanooga, Tennessee
Ports
Nashville, Tennessee - CLARKSVILLE, TENNESSEE - Paducah, Kentucky - Savannah, Tennessee - Florence, Alabama - Decatur, Alabama - Chattanooga, Tennessee - View more ports
Ports
- Chattanooga, Tennessee
- Decatur, Alabama
- Florence, Alabama
- Savannah, Tennessee
- Paducah, Kentucky
- CLARKSVILLE, TENNESSEE
- Nashville, Tennessee
Ports
Chattanooga, Tennessee - Decatur, Alabama - Florence, Alabama - Savannah, Tennessee - Paducah, Kentucky - CLARKSVILLE, TENNESSEE - Nashville, Tennessee - View more ports
7 Night The Tennessee Rivers (Chattanooga To Nashville)
2025 sail dates: Aug 13,
Ports
- St. Louis, Missouri
- Hannibal, Missouri
- RIVER CRUISING
- MUSCATINE, IOWA
- Dubuque, Iowa
- Winona, Minnesota
- Red Wing, Minnesota
- St. Paul, Minnesota
Ports
St. Louis, Missouri - Hannibal, Missouri - RIVER CRUISING - MUSCATINE, IOWA - Dubuque, Iowa - Winona, Minnesota - Red Wing, Minnesota - St. Paul, Minnesota - View more ports
Top positive review
Top critical review
Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
---|---|---|---|---|---|---|
|
See Offers |
N/A |
N/A |
$5635* |
$7795* |
|
|
N/A |
N/A |
$5635* |
$7795* |
||
|
See Offers |
N/A |
N/A |
$5635* |
$7795* |
|
|
N/A |
N/A |
$5635* |
$7795* |
Ports
- Amelia Island, Florida
- JEKYLL ISLAND, GEORGIA
- Savannah, Georgia
- HILTON HEAD ISLAND, SOUTH CAROLINA
- BEAUFORT, SOUTH CAROLINA
- Charleston, South Carolina
Ports
Amelia Island, Florida - JEKYLL ISLAND, GEORGIA - Savannah, Georgia - HILTON HEAD ISLAND, SOUTH CAROLINA - BEAUFORT, SOUTH CAROLINA - Charleston, South Carolina - View more ports
7 Night Historic South & Golden Isles (Jacksonville To Charleston)
2025 sail dates: Dec 27
Top positive review
Top critical review
Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
---|---|---|---|---|---|---|
|
See Offers |
N/A |
$5270* |
$6155* |
$8195* |
|
|
N/A |
$5270* |
$6155* |
$8195* |
||
|
See Offers |
N/A |
$5270* |
$6155* |
$8195* |
|
|
N/A |
$5270* |
$6155* |
$8195* |
||
|
See Offers |
N/A |
$5630* |
$6575* |
$8755* |
|
|
N/A |
$5630* |
$6575* |
$8755* |
||
|
See Offers |
N/A |
$5990* |
$6995* |
$9315* |
|
|
N/A |
$5990* |
$6995* |
$9315* |
||
|
See Offers |
N/A |
$5990* |
$6995* |
$9315* |
|
|
N/A |
$5990* |
$6995* |
$9315* |
||
|
See Offers |
N/A |
$5990* |
$6995* |
$9315* |
|
|
N/A |
$5990* |
$6995* |
$9315* |
Ports
- WASHINGTON, D.C. USA
- ANNAPOLIS, MARYLAND
- ST. MICHAELS, MARYLAND
- CAMBRIDGE, MARYLAND
- RIVER CRUISING
- Norfolk, Virginia
- Williamsburg, Virginia
- Mt Vernon, Virginia
Ports
WASHINGTON, D.C. USA - ANNAPOLIS, MARYLAND - ST. MICHAELS, MARYLAND - CAMBRIDGE, MARYLAND - RIVER CRUISING - Norfolk, Virginia - Williamsburg, Virginia - Mt Vernon, Virginia - View more ports
10 Night American Revolution (Washington D.C. Roundtrip)
2025 sail dates:
Top positive review
Top critical review
Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
---|---|---|---|---|---|---|
|
See Offers |
N/A |
N/A |
$9595* |
$12775* |
|
|
N/A |
N/A |
$9595* |
$12775* |
||
|
See Offers |
N/A |
N/A |
$9595* |
$12775* |
|
|
N/A |
N/A |
$9595* |
$12775* |
||
|
See Offers |
N/A |
N/A |
$9020* |
$12010* |
|
|
N/A |
N/A |
$9020* |
$12010* |
Ports
- Jacksonville, Florida
- Amelia Island, Florida
- RIVER CRUISING
- ST. AUGUSTINE, FLORIDA
- Port Canaveral, Florida
- West Palm Beach, Florida
- KEY BISCAYNE, FLORIDA
- Key West, Florida
- MARCO ISLAND, FLORIDA
- PUNTA GORDA, FLORIDA
- ST. PETERSBURG, FLORIDA
Ports
Jacksonville, Florida - Amelia Island, Florida - RIVER CRUISING - ST. AUGUSTINE, FLORIDA - Port Canaveral, Florida - West Palm Beach, Florida - KEY BISCAYNE, FLORIDA - Key West, Florida - MARCO ISLAND, FLORIDA - PUNTA GORDA, FLORIDA - ST. PETERSBURG, FLORIDA - View more ports
14 Night Grand Florida Coast & Keys (Jacksonville To St. Petersburg)
2025 sail dates: Nov 01
2026 sail dates:
Top positive review
Top critical review
Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
---|---|---|---|---|---|---|
|
See Offers |
N/A |
N/A |
$12380* |
$14530* |
|
|
N/A |
N/A |
$12380* |
$14530* |
||
|
See Offers |
N/A |
N/A |
$12360* |
$14530* |
|
|
N/A |
N/A |
$12360* |
$14530* |
Ports
- Baltimore, Maryland
- ST. MICHAELS, MARYLAND
- Norfolk, Virginia
- KITTY HAWK, NORTH CAROLINA
- Morehead City, North Carolina
- Wilmington, North Carolina
- Charleston, South Carolina
- BEAUFORT, SOUTH CAROLINA
- HILTON HEAD ISLAND, SOUTH CAROLINA
- Savannah, Georgia
- ST. SIMONS ISLAND, GEORGIA
- JEKYLL ISLAND, GEORGIA
- FERNANDINA BEACH, FL
- Amelia Island, Florida
- Jacksonville, Florida
Ports
Baltimore, Maryland - ST. MICHAELS, MARYLAND - Norfolk, Virginia - KITTY HAWK, NORTH CAROLINA - Morehead City, North Carolina - Wilmington, North Carolina - Charleston, South Carolina - BEAUFORT, SOUTH CAROLINA - HILTON HEAD ISLAND, SOUTH CAROLINA - Savannah, Georgia - ST. SIMONS ISLAND, GEORGIA - JEKYLL ISLAND, GEORGIA - FERNANDINA BEACH, FL - Amelia Island, Florida - Jacksonville, Florida - View more ports
14 Night East Coast Inland Passage (Baltimore To Jacksonville)
2025 sail dates:
2026 sail dates: Oct 27
Top positive review
Top critical review
Partners | Bonus Offers | Inside | Oceanview | Balcony | Suite | |
---|---|---|---|---|---|---|
|
See Offers |
N/A |
N/A |
$12360* |
$16325* |
|
|
N/A |
N/A |
$12360* |
$16325* |
||
|
See Offers |
N/A |
N/A |
$12360* |
$16325* |
|
|
N/A |
N/A |
$12360* |
$16325* |
All prices are per person based on double occupancy and do not include port/government fees and gratuities.