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American Cruise Line Cruises to River Cruises - United States 125 cruises on American Cruise Line found

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Ports

  • ST. PETERSBURG, FLORIDA
  • FORT MYERS, FLORIDA
  • Key West, Florida
  • MARCO ISLAND, FLORIDA
  • PUNTA GORDA, FLORIDA
View more ports

Ports

ST. PETERSBURG, FLORIDA - FORT MYERS, FLORIDA - Key West, Florida - MARCO ISLAND, FLORIDA - PUNTA GORDA, FLORIDA - View more ports

American Legend S

2024 sail dates: Dec 23,

2025 sail dates: Jan 06, Jan 13, Jan 20, Jan 27, Feb 03, Feb 10, Feb 17, More

$6995*
$999/night*
Balcony
View Deal
$6995* luxuryonly.com $6995* dreamvacations.com
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Ports

  • Memphis, Tennessee
  • RIVER CRUISING
  • Vicksburg, Mississippi
  • Natchez, Mississippi
  • St. Francisville, Louisiana
  • Baton Rouge, Louisiana
  • Houmas House Plantation, Louisiana
  • New Orleans, Louisiana
View more ports

Ports

Memphis, Tennessee - RIVER CRUISING - Vicksburg, Mississippi - Natchez, Mississippi - St. Francisville, Louisiana - Baton Rouge, Louisiana - Houmas House Plantation, Louisiana - New Orleans, Louisiana - View more ports

American Melody S

5.0
(8 Reviews)

2024 sail dates:

2025 sail dates: Apr 05, Apr 19, May 03, May 17, More

$5275*
$754/night*
Balcony
View Deal
$5275* luxuryonly.com $5275* dreamvacations.com
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$5495*

$7790*

 

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Ports

  • Jacksonville, Florida
  • Amelia Island, Florida
  • JEKYLL ISLAND, GEORGIA
  • Savannah, Georgia
  • HILTON HEAD ISLAND, SOUTH CAROLINA
  • BEAUFORT, SOUTH CAROLINA
  • Charleston, South Carolina
View more ports

Ports

Jacksonville, Florida - Amelia Island, Florida - JEKYLL ISLAND, GEORGIA - Savannah, Georgia - HILTON HEAD ISLAND, SOUTH CAROLINA - BEAUFORT, SOUTH CAROLINA - Charleston, South Carolina - View more ports

American Liberty XL

5.0
(1 Reviews)

2024 sail dates: Dec 28

2025 sail dates: Feb 15, Mar 01, Mar 15, Mar 29, Apr 26, May 10, Nov 15, Nov 29, Dec 13, Dec 27, More

$6245*
$892/night*
Balcony
View Deal
$6245* luxuryonly.com $6245* dreamvacations.com
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Ports

  • Clarkston, Washington
  • CRUISE SNAKE RIVER, PACIFIC NORTHWEST, USA
  • Pendleton, Oregon
  • THE DALLES, OREGON
  • Cruise Columbia River
  • Mount St. Helens, Washington
  • Astoria, Oregon
  • Portland, Oregon
View more ports

Ports

Clarkston, Washington - CRUISE SNAKE RIVER, PACIFIC NORTHWEST, USA - Pendleton, Oregon - THE DALLES, OREGON - Cruise Columbia River - Mount St. Helens, Washington - Astoria, Oregon - Portland, Oregon - View more ports

American Harmony S

5.0
(6 Reviews)

2024 sail dates:

2025 sail dates: May 03, May 31, Jun 14, Jun 28, Jul 12, Jul 26, Aug 09, Aug 23, Sep 20, Oct 04, Oct 18, Nov 01, More

$5595*
$799/night*
Balcony
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$5595* luxuryonly.com $5595* dreamvacations.com
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$7890*

 

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Ports

  • Charleston, South Carolina
  • BEAUFORT, SOUTH CAROLINA
  • HILTON HEAD ISLAND, SOUTH CAROLINA
  • Savannah, Georgia
  • JEKYLL ISLAND, GEORGIA
  • Amelia Island, Florida
  • Jacksonville, Florida
View more ports

Ports

Charleston, South Carolina - BEAUFORT, SOUTH CAROLINA - HILTON HEAD ISLAND, SOUTH CAROLINA - Savannah, Georgia - JEKYLL ISLAND, GEORGIA - Amelia Island, Florida - Jacksonville, Florida - View more ports

American Eagle S

5.0
(2 Reviews)

2024 sail dates: Dec 29

2025 sail dates: Mar 31, Apr 14, Apr 28, May 12, Dec 12, More

$4880*
$697/night*
Oceanview
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$4880* luxuryonly.com $4880* dreamvacations.com
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Ports

  • Memphis, Tennessee
  • RIVER CRUISING
  • Vicksburg, Mississippi
  • Natchez, Mississippi
  • St. Francisville, Louisiana
  • Baton Rouge, Louisiana
  • Houmas House Plantation, Louisiana
  • New Orleans, Louisiana
View more ports

Ports

Memphis, Tennessee - RIVER CRUISING - Vicksburg, Mississippi - Natchez, Mississippi - St. Francisville, Louisiana - Baton Rouge, Louisiana - Houmas House Plantation, Louisiana - New Orleans, Louisiana - View more ports

American Symphony S

4.2
(4 Reviews)

2024 sail dates: Dec 30

2025 sail dates: Jul 16, Aug 27, Nov 05, More

$4415*
$631/night*
Balcony
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$4415* luxuryonly.com $4415* dreamvacations.com
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Ports

  • WASHINGTON, D.C. USA
  • ANNAPOLIS, MARYLAND
  • ST. MICHAELS, MARYLAND
  • CAMBRIDGE, MARYLAND
  • RIVER CRUISING
  • Norfolk, Virginia
  • Williamsburg, Virginia
  • Mt Vernon, Virginia
View more ports

Ports

WASHINGTON, D.C. USA - ANNAPOLIS, MARYLAND - ST. MICHAELS, MARYLAND - CAMBRIDGE, MARYLAND - RIVER CRUISING - Norfolk, Virginia - Williamsburg, Virginia - Mt Vernon, Virginia - View more ports

American Legend S

2025 sail dates: Mar 15, Mar 25, Apr 04, Apr 14, Apr 24, May 04, May 14, More

2026 sail dates: May 22,

$8995*
$900/night*
Balcony
View Deal
$8995* luxuryonly.com $8995* dreamvacations.com
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Ports

  • Seattle, Washington
  • ANACORTES, WASHINGTON
  • FRIDAY HARBOR, SAN JUAN ISLAND, WASHINGTON
  • CRUISE SAN JUAN ISLANDS
  • Victoria, British Columbia
  • PORT TOWNSEND, WASHINGTON
  • POULSBO, WA
View more ports

Ports

Seattle, Washington - ANACORTES, WASHINGTON - FRIDAY HARBOR, SAN JUAN ISLAND, WASHINGTON - CRUISE SAN JUAN ISLANDS - Victoria, British Columbia - PORT TOWNSEND, WASHINGTON - POULSBO, WA - View more ports

American Constellation S

4.9
(7 Reviews)

2025 sail dates: Apr 07, Apr 14, Apr 28, May 05, Sep 30, Oct 07, Oct 21, More

$4700*
$671/night*
Oceanview
View Deal
$4700* luxuryonly.com $4700* dreamvacations.com
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Read all 7 American Constellation reviews

Ports

  • Seattle, Washington
  • ANACORTES, WASHINGTON
  • FRIDAY HARBOR, SAN JUAN ISLAND, WASHINGTON
  • Victoria, British Columbia
  • PORT TOWNSEND, WASHINGTON
  • POULSBO, WA
View more ports

Ports

Seattle, Washington - ANACORTES, WASHINGTON - FRIDAY HARBOR, SAN JUAN ISLAND, WASHINGTON - Victoria, British Columbia - PORT TOWNSEND, WASHINGTON - POULSBO, WA - View more ports

American Constitution XL

5.0
(4 Reviews)

2025 sail dates: Apr 12, Apr 19, Apr 26, May 03, Sep 21, Sep 28, Oct 05, Oct 12, More

2026 sail dates: Mar 28, Apr 04, Apr 11, Apr 18, Apr 25, May 02, Sep 20, Sep 27, Oct 04, Oct 11, Oct 18, More

$4600*
$657/night*
Oceanview
View Deal
$4600* luxuryonly.com $4600* dreamvacations.com
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Read all 4 American Constitution reviews
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$5490*

$7295*

 

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$6240*

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$5425*

$6240*

$8290*

 

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$5425*

$6240*

$8290*

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$5100*

$5865*

$7795*

 

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$5100*

$5865*

$7795*

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$5100*

$5865*

$7795*

 

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$5100*

$5865*

$7795*

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$5100*

$5865*

$7795*

 

N/A

$5100*

$5865*

$7795*

Ports

  • WASHINGTON, D.C. USA
  • Norfolk, Virginia
  • Williamsburg, Virginia
  • Yorktown, Virginia
  • Mt Vernon, Virginia
  • RIVER CRUISING
  • CAMBRIDGE, MARYLAND
  • ST. MICHAELS, MARYLAND
  • ANNAPOLIS, MARYLAND
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Ports

WASHINGTON, D.C. USA - Norfolk, Virginia - Williamsburg, Virginia - Yorktown, Virginia - Mt Vernon, Virginia - RIVER CRUISING - CAMBRIDGE, MARYLAND - ST. MICHAELS, MARYLAND - ANNAPOLIS, MARYLAND - View more ports

American Legend S

2025 sail dates:

2026 sail dates: Apr 12, May 02, May 12, More

$9020*
$902/night*
Balcony
View Deal
$9020* luxuryonly.com $9020* dreamvacations.com
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Partners Bonus Offers Inside Oceanview Balcony Suite
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$9020*

$12010*

 

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$9020*

$12010*

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$9020*

$12010*

 

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$9020*

$12010*

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$9595*

$12775*

 

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$9595*

$12775*

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$9595*

$12775*

 

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$9595*

$12775*

51 - 60 of 125

All prices are per person based on double occupancy and do not include port/government fees and gratuities.

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